Painkiller Jane is a SuperHero character that originated in a comic book series, made a brief B-movie appearance, then migrated to a short-lived TV series on the [[Creator/{{Syfy}} Sci Fi Channel]].

All the three versions have in common are that they are virtually immortal, ass-kicking hot women. The names, backgrounds, occupations and hair color all mutate wildly in transition.

Not related in any way to the ([[VideoGame/BrutalLegend Second]]) '''[[VideoGame/{{Painkiller}} MOST METAL VIDEOGAME EVER.]]'''


The ComicBook started with Event Comics and is now at Dynamite Comics. Jane Vasko (with a "k") was an undercover cop investigating TheMafia, when she got [[StuffBlowingUp exploded]] by a rival gangster known only as Adam, who was at ground zero without a scratch. Somehow, Adam revives her, makes her unkillable, and then disappears. She drops off the force and becomes a vigilante, [[NotWearingTights eschewing spandex]] in favor of lots of bandages ([[BringMyRedJacket 'cause she bleeds a while]] before healing up), a BadassLongcoat and CoolShades. She is an expert at close-combat and normally carries [[GunsAkimbo twin automatics]].

The MadeForTVMovie was a [[Creator/{{Syfy}} Sci Fi Channel]] [[Film/SyfyChannelOriginalMovie Original]], [[BrutalHonesty meaning it sucked]]. Still, it had Emmanuelle Vaugier, even if she spent half the film in a cheap wig.

This version is radically different from the original. Captain Jane Browning, a U.S. Special Forces soldier (never mind that they don't have any female members) is hit by TheVirus and becomes a SuperSoldier. She then tries to discover who to seek revenge against (not just for being CursedWithAwesome, but because her squadmates didn't share her good luck, and died from the bioweapon instead).

The TV series was another new direction. Former [[Film/Terminator3RiseOfTheMachines Terminatrix]] Creator/KristannaLoken was Jane Vasco (with a "c"), once again a cop (this time in the DEA), recruited for a special quasigovernmental FiveManBand to hunt down "Neuro"s, neurological abberants with [[SuperpowerfulGenetics mutations that gave them superpowers]], and stick a microchip in their brains to [[BroughtDownToNormal depower them]]. Jane discovers [[ContrivedCoincidence quite by accident]] that she has a HealingFactor. From then on it's MonsterOfTheWeek, with every episode [[GoodThingYouCanHeal having Jane find some reason]] to get mauled, mutilated, shot, poisoned or given brain cancer. And [[{{Wangst}} not knowing if she'll get better]], even if the audience has no doubt.
!!Tropes hit in all three:
* AppliedPhlebotinum
* BandageBabe
* BiTheWay
* EnemyWithin
* GoodThingYouCanHeal
* HealingFactor
* MonsterOfTheWeek
* NotWearingTights

!!Tropes in the comic
* IntercontinuityCrossover: With ''Franchise/{{Terminator}}'' and ''Comicbook/ThePunisher''.