!!Wendy Watson
-> '''Played By:''' Creator/NatalieMorales

The POV character, she was a temp working at [[FunWithAcronyms A.N.D. Labratories]] when a genetic abomination reminiscent of a {{hentai}} tentacle monster attacked her and the Middleman stepped in. Now she's his apprentice/sidekick/partner.
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* ActionGirl: After her training with Sensei Ping.
%%* AlliterativeName
* BirdsOfAFeather: With Tyler.
%%* BrainyBrunette
%%* DeadpanSnarker
%%* DisappearedDad
%%* GenreSavvy
* IHaveManyNames: Lacey calls her "Dub-Dub" while the Middleman calls her "Dubbie." Tyler calls her "Dubs" and Noser always uses her full name. Ida uses a variety of sarcastic and/or insulting nicknames.
* JumpedAtTheCall: Her reaction to the knowledge that ghosts exist? "Oh cool!"
** "Cool!" is also Wendy's reaction to Zombies. And Vampires, and... you get the point.
** RefusedTheCall: At first. But it was mostly due to The Middleman and Ida framing her for the destruction of her last workplace that freaked her out. But then Ben decided to break-up with her and film it and the rest is history.
** Her accepting the giant monster's existence and leaping at it with a letter opener instead or running and screaming is what got her the job in the first place. She jumped at the call before there was even a call.
%%* MartialPacifist: Parodied.
* OrphansPlotTrinket: Her dad's lighter (though she's technically not an orphan).
%%* OtakuSurrogate
* RaceLift: She was a red-haired caucasian in the original comic. This leads to a bit of AdaptationExpansion in "The Sino-Mexican Revelation", which was adapted from the second volume of the comic, since now Wendy speaks Spanish.
* SpicyLatina: Invoked by Middleman '69, who refers to Wendy as "a hot and spicy Spanish girl."
* TechnicalPacifist: Wendy hates guns, but has a bit of a geeky affection for the sci-fi weapons the Middle organization uses. She also loves training with Sensei Ping, and she frequently protests the Middleman's tendencies toward violence. But she had no problem whatsoever beating a venomous Peruvian Pike to death.
* UnfazedEveryman: Her reaction to the lab explosion is how she got the job.
* YouNeedToGetLaid: Well, at least Lacey thinks so.

!!The Middleman
-> '''Played By:''' Creator/MattKeeslar

The titular character, he's a LegacyCharacter who fights comic book type monsters and {{Mad Scientist}}s with an array of gadgetry and good old fashioned fisticuffs. Works for [[HeroesRUs O2STK]], the Organization 2 Secret To Know.
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* AllergicToLove: A mild case.
* AlliterativeName: [[spoiler: Clarence Colton]].
%%* BadassInANiceSuit
%%* BadassNormal
* BigBrotherInstinct: Stated himself that thinks of Wendy like a little sister.
* {{Deuteragonist}}: While his name is the show's title and Matt Keeslar has top billing, this is Wendy's story much more than it is his.
* EveryoneCallsHimBarkeep: He is only ever addressed by variations on his title and job description, such as "Middleman", "MM", "Double-M", "Wendy's Boss".
* DiscoDan: He acts like a GoldenAge square jawed super hero.
* GenreSavvy: He's been around the block enough to understand that the universe operates on genre work rules; it's a key part of his initial pitch to Wendy.
%%* GoshdangItToHeck
* NoNameGiven: He never gives out his real name. Even under the effects of a truth gas, all he'll divulge is that he shares the same name as his father.
* StarCrossedLovers: With Lacey.


!!Ida
-> '''Played By:''' Mary Pat Gleeson

The Middleman's robot assistant stuck in the form of a snarky middle-aged schoolmarm. Is constantly saying that Wendy Watson is a stoner.
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%%* AIIsACrapshoot
%%* DeadpanSnarker
* DisneyDeath: The one from the series' first half actually does die, but [=O2STK=] promptly sends an identical replacement.
%%* {{Jerkass}}
%%* RidiculouslyHumanRobot

!!Lacey Thornfield
-> '''Played By:''' Creator/BritMorgan

Wendy's roommate in their illegal sublet, she's an animal rights activist as well as another young, photogenic artist. She's also got the hots for the Middleman.
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* GranolaGirl: A fairly sympathetic example.
* MissingMom: Dr. Barbara Thornfield, MD, PHD.
* StarCrossedLovers: With the Middleman, but she has no idea why.
* TwoLinesNoWaiting: Usually there's a A-plot with MM and WW and a B-plot with Lacey and Noser/Pip/someone else. Sometimes they converge.

!!Noser
-> '''Played By:''' Jake Smollett

Another tenant in Wendy's building, he usually stands out in the hall with his guitar and speaks [[WaxingLyrical mostly in pop culture references]]. [[InformedAbility We never actually see him play.]]
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%%* {{Cloudcuckoolander}}
* TheDreaded: Noser's talent and reputation as a ventriloquist are so great that the mere mention of his name causes one contestant in a competition to drop out, leave and quite possibly quit competing all together.
* InformedAbility: Not only his guitar playing skills, but his skills as a ventriloquist.
* OldShame: His childhood career as a ventriloquist.
%%* OnlyOneName
* ThePiratesWhoDontDoAnything: Noser spends an awful lot of time not playing the guitar. He also has an incidental sideline in not riding a motorcycle, and an entire episode built around his not being a ventriloquist.
* WaxingLyrical: He loves speaking in song lyrics.

!!Roxy Wasserman
-> '''Played By:''' Creator/ElaineHendrix

A reformed succubus who works as a fashion designer and fronts a modeling agency, she helps MM with mystical problems.
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* DarkIsNotEvil: The whole point of her fashion agency actually. It gives Succubi and Incubi a place to work and get reformed like she did.
%%* ForHalloweenIAmGoingAsMyself

!!Sensei Ping
-> '''Played By:''' Creator/MarkDacascos
Trainer for both the Middleman and Wendy. Possibly awesome incarnate. Knows the [[TouchOfDeath Wu-Han Thumb of Death]].
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%%* BadassNormal
* HeWhoMustNotBeSeen: Though mentioned a lot, he's seen in a total of one episode.
%%* JerkAss
%%* LargeHam: He's played by Mark Dacascos. Nuff said.%%Zero-context example, Word Cruft.
%%* MickeyMousing: His ''every move''.%%Zero-context example.
%%* OlderThanTheyLook
%%* ThirdPersonPerson

!!Tyler Ford
-> '''Played By:''' Brendan Hines

A prior candidate for the Middleman's apprentice, instead he met Wendy, forgot her with [[EasyAmnesia two day amnesia]], then met her again and became her boyfriend.
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* EasyAmnesia: Knocked on the head once and has two day amnesia. Yeah, just go with it.
* MissedTheCall: His roommate mislaid his job offer letter.
%%* ThePeteBest

!!Interrodroid 3000 through 7000
A training robot that helps around the Middleman HQ.
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* TheChewToy: It tends to get its head ripped off. A lot.

!!Pip
-> '''Played By:''' Drew Tyler Bell
Son of the owner of the apartment building Wendy and Lacey live in, he's a really big {{jerkass}}.
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* BadassPreacher: In the Mirror-Middleverse.
* ContemplateOurNavels: His one man act was called "Hey, Mr. God, What About Me?"
* JerkAss: A really, really big one, and a plagiarist on top of that.

!!Joe 90
-> '''Played By:'''
Another resident of Wendy's and Lacey's apartment, a failed law school student who makes very phallic sculptures.
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!!Manservant Neville
-> '''Played By:''' Creator/MarkSheppard

The CEO of FATBOY Industries, which makes everything from coffee to ice cream to the uMaster, a virtually featureless cube that just happens to be ''the'' cool gadget that every young, creative artistic type just has to have.
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* AGodAmI: The Doomsday Armageddon Apocalypse.
* BlandNameProduct: The uMaster, which is treated as a synthesis of every cool i-gadget Apple has ever made (but only to the extent that everyone has to have one, as we are never shown what, if anything, the uMaster actually does.)
* CorruptCorporateExecutive: Maybe. In the altUniverse, he was good, so he might be evil in this universe. Confirmed by the Doomsday Armageddon Apocalypse. He ends up very nearly taking over the world.
* EvilIsHammy: Mark Sheppard has ''way'' too much fun at the live reading, even overacting his death.
* InkSuitActor: The comic incarnation of the character was very different to the TV version, but was deliberately drawn to resemble Creator/MarkSheppard long before the chance to actually cast him came along.
* WellIntentionedExtremist: His plan to [[spoiler: become a Living God]] is environmentally motivated.

!!Ben
Wendy's boyfriend of over a year, breaks up with her for a film school project.
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* {{Jerkass}}: Granted he feels terrible about the whole "breaking up with Wendy for a project" thing at first, he still did something so selfish in the first place and later posted it online.
* TrueArtIsAngsty: [[invoked]] The reason he breaks up with Wendy; his professor didn't think he had enough pain in his life.

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