!!Stanley Ipkiss / The Mask (JimCarrey \ RobPaulsen)
* ActingUnnatural - Once he gets ahold of the Mask, it happens a lot.
* AdaptationalHeroism: In the comic, Ipkiss gradually turns into a psychopath undr the influence of the Mask. In the movie, he is a much nicer guy, and his only "crimes" as the Mask are robbing a bank, messing with the police and eliminating the BigBad. In the Animated Series, he is still not above trolling authority and people as a whole, but Stanley otherwise tries to use the Mask's power as a force of good, with relative success.
* AdaptationDistillation: Though much of Ipkiss' personality is the same in the beginning of both the comics and the movie. In the comics Stanley becomes more psychotic and abusive whenever he doesn't have the mask on.
* BadLiar - Somebody stole his pajamas!
* BecomingTheMask: literally.
* BeneathTheMask
* ButtMonkey: whether it's the comic, the movie or the animated series, Stanley tends to get treated like crap by almost everyone other than his closest friends, though he learns to stand up for himself as the film goes on. In the comic, that serves as his motive for revenge.
* ChekhovsGag - Stanley's favorite cartoons become the traits of the Mask (for starters, he spins like [[WesternAnimation/LooneyTunes Taz]]).
** His head even morphs into the Tex Avery wolf from ''RedHotRidingHood''.
* {{Cloudcuckoolander}} - The Mask personality.
* ComicallyInvincibleHero - Again, with the powers of the Mask.
* ExtremeDoormat: Before he TookALevelInBadass in the film.
* FusionDance: Kinda. There is no dance involved, but in the animated episode "Split Personality", the Mask is split in two. In an attempt to see if it works, Stanley puts the half on. It works to say the least, resulting in a literal fusion of the two. One half Stanley, one half the Mask.
-->'''Stanley Half''': So this is what I do as you...
-->'''The Mask Half''': It's the voodoo I do!
* HeroicComedicSociopath - Except in the comics, where he's a straight-up VillainProtagonist.
* IHaveThisFriend - Stanley claims to be old college buddies with "The Mask".
* LargeHam: both as the Stanley and the Mask in the movie. In the animated series, Stanley is portrayed as a bit less hammy and more shy, but the Mask is still incredibly hammy.
* SexierAlterEgo - Note that he's not more physically attractive (unless you're into that sort of thing), but more confident and impulsive (and gets RealityWarper powers), and that's why he gets the LoveInterest in the end.
* SlasherSmile
* SubmissiveBadass
* {{Troll}}: As the Mask, especially in the Animated Series.
* WeaksauceWeakness: Common cold in the Animated Series.

!!Milo
* ActionPet
* {{Badass}}
* CanineCompanion
* Creator/FrankWelker: His voice actor on the cartoon series.
* EvilDetectingDog - While not evil (at least in the right hands) Milo could tell from the start that their was something strange about the Mask.
* NonHumanSidekick
* TeamPet - To an extent.

!!Tina Carlyle (CameronDiaz)
* ChuckCunninghamSyndrome - When the movie was adapted into a Saturday morning cartoon, Tina was never seen and her existence was not acknowledged.
* DefrostingIceQueen - Not cold, just a little aloof at first
* DistressedDamsel
* {{Expy}}: Of Kathy, Stanley's girlfriend, from the comics.
* FemmeFatale
* MsFanservice
* ReformedCriminal
* SilkHidingSteel

!!Charlie Schumaker (Richard Jeni \ Mark L. Taylor)
* JerkassFacade - Comes across as ''really'' selfish at first, but he helps Stanley when he really needs him.
* TheLancer
* OnlyFriend - Charlie does appear to be Stanley's only friend.
* TookALevelInBadass - "Officers, arrest those men! ...I've always wanted to say that."
* TookALevelInJerkass - His redeeming qualities disappear in the animated series.
* WhoNeedsEnemies - He'll drop a conversation with Stanley to talk to a pretty girl.
* WithFriendsLikeThese - He's not always good at being there for Stanley, see above.

!!Lieutenant Kellaway (Peter Riegert \ Neil Ross)
* ButtMonkey / TheChewToy: ''Especially'' in the Animated Series.
* TheComicallySerious
* HeroAntagonist
* InspectorJavert: In the cartoon, he's got a grudge. In the comics though, it's justified.
* NoSenseOfHumor - See below.
** Moreso in the comics, where he's trying to hunt down and stop an artifact that turns anyone who wears it into an unstoppable, psychotic mass-murderer.
* ShoutOut - In the cartoon, he wears a brown raincoat, much like another TV police lieutenant with no first name given.
* StraightMan - With almost no sense of humor.
* TookALevelInJerkass: His dislike of the Mask is completely justified in the comic, and while he is misguided HeroAntagonist in the movie, he overall does nothing the could be considered unreasonable. In the Animated Series, on the other hand, he keeps treating the Mask like a criminal and chasing him, not matter how many times he saw him save the day or arrest actually dangerous criminals.

!!Detective Doyle (Jim Doughan \ JimCummings)
* ButtMonkey
* CaptainObvious
* CluelessDetective - Don't bother trying to give him a hint in Pig Latin.
** He's even more clueless in the cartoon, making one wonder how the hell could he have passed the police academy exams.
* FriendlyEnemy - Tried to shake Stanley's hand after he saved the day.
* PluckyComicRelief
* TookALevelInDumbass: Both a film-wise and adaptation wise. In his initial scene at the bank, he seems to be quite intelligent and competent. By the time we see him at the park, he's suddenly a ditz and by the film's end he's a certified idiot (though some of that may have been him being influenced by the Mask's power). The cartoon made him even dumber.

!!Detective Lionel
* AngryBlackMan - Lionel turned into one when Kellaway/Big Head started fighting the police, and challenged Big Head to a fist fight. [[spoiler: Big Head almost killed him, and would have if Kellaway hadn't regained control of himself.]]
* BlackBestFriend - Oh hell, Lionel is Kellaway's ONLY friend.
* BlackDudeDiesFirst - Subverted, as Lionel is one of the few people Big Head doesn't end up killing.
* IdiotBall - Lionel challenged Big Head to a fist fight. This went as well as one would expect...
* TokenMinority - Lionel is the only member of the named main cast who's black.
* TheWatson - He's not only Kellaway's partner, but one of the few people in the police force that Kellaway even trusts.
* WhiteDudeBlackDude - Subverted. With Kellaway and Lionel it's more "angry dude, calm dude"., respectively.

!!Mrs. Peenman (Nancy Fish \ TressMacNeille)
* ButtMonkey: And how! Especially in the animated series (though, given how much of a mean old lady she is, Peenman is more of an AssholeVictim).
* [[GrumpyOldMan Grumpy Old Woman]]
* HairTriggerTemper
* JerkAss

!!Peggy Brandt (Amy Yasbeck \ Heidi Shannon)
* FaceHeelTurn: In the movie, she turns Stanley over to Tyrell for money.
* GoingForTheBigScoop: In the cartoon.
* HotScoop
* IntrepidReporter: In the cartoon.
* KarmaHoudini: In the movie, since [[spoiler:the scene of Peggy getting shoved in the printing press by Dorian and coming out as a bloodied newspaper that has her death on the front page]] was cut. She and Stanley became friends in the cartoon, on the other hand. But he never got over her selling him out.
* MsFanservice: In the cartoon.
* SparedByTheAdaptation: Since [[spoiler:her death was removed from the theatrical cut of the movie]], she is featured as still alive in the animated series.
* TookALevelInKindness: In the cartoon; she is still constantly trying to exploit the Mask to get a scoop, but she at least no longer acts antagonistic toward Stanley.
* WhatHappenedToTheMouse: She disappears after Dorian puts on the mask and was presumably allowed by Tyrell and his men to walk away unharmed. Originally, [[spoiler:he would follow up by tossing her [[CruelAndUnusualDeath into a newspaper printing press.]]]]

!!Dorian Tyrell (Peter Greene)
* BerserkButton - DON'T COME ANYWHERE NEAR HIS GIRL!
* BigBad: In the movie.
* DomesticAbuser - Don't see too much in the movie, but it seems pretty obvious anyway.
* EvilMakesYouUgly: [[spoiler:While the Mask makes Stanley bald and cartoonish, Dorian instead gets a demonic GameFace that even retains the hair.]]
* HairTriggerTemper
* LawOfDisproportionateResponse - Get pushed around by the "Big Boss"... Blow up his Casino and everyone in it.
* RedEyesTakeWarning: [[spoiler:Wearing the Mask]].
* TheStarscream: To Niko.
* UnstoppableRage - When [[spoiler:he wears the Mask]].

!!Dr. Pretorius (TimCurry)
* ArchEnemy / BigBad: in the animated series.
* {{Cyborg}}
* {{Expy}}: He looks a lot like Eugene Rapaz, a drug dealer from the comics. Tone down the mohawk and replace the eye lenses with glasses...
* HammerSpace: The tiny circular base of his head has the mechanisms to drive six small legs, a computer interface jack, various tools, a neural interface and circuitry, and one would assume a complex life support system to keep him alive without a body (albeit such a system may be meant for short term use as he's almost always attached to his robotic body).
* LosingYourHead: When it happens, it grows spider legs!
* MadScientist
* ShoutOut: He shares his name with the mad scientist from ''Film/BrideOfFrankenstein''.
* TimCurry: His voice actor on the cartoon.
* VillainDecay: In his first appearance, he was a more or less serious and dangerous antagonist who came up with a relatively credible plan and almost killed Stanley. In later episodes, while he would still turn out to be a threat occasionally, his plans became more cartoonish, and he starts becoming more of a ButtMonkey like other villains.

!!Walter
* ArchEnemy: In the comics.
* BadAss: Both in the comics and the animated series, he is one of the few guys who can actually give the Mask/Big Head a run for his money.
** AdaptationalBadass: In the comic, he was incredibly strong and durable, but could eventually be taken down with enough beating. In the animated series, he is flat-out NighInvulnerable even to the Mask's supernatural powers, and can only be defeated by being sent away of trapt somewhere).
* TheBrute: More so in the comics than the cartoon, where he was a mob hitman and enforcer.
* TheDragon: To Dr. Pretorius in the cartoon, to the mob in the comics.
* ImplacableMan
* NighInvulnerable: In the cartoon. In the comics he could be taken down with enough of a beating.
* PresidentEvil: A comic (likely based on the cartoon) had him running for Mayor of Edge City.
* SelfMutilationDemonstration: Just to be clear here- comic Walter can bleed, though it doesn't seem to really hurt him. Cartoon Walter is impervious to wounds. That said... in the comics he had a disgusting habit of cutting himself just to mess with people's heads.
* TheVoiceless