[[center: [-[[Characters/TengenToppaGurrenLagann Main Character Index]] | [[Characters/TengenToppaGurrenLagannMainCharacters Main Characters]] | [[Characters/TengenToppaGurrenLagannMecha Mecha]] | '''Antagonists''' | [[Characters/TengenToppaGurrenLagannSecondaryCharacters Secondary characters]]]]-]

This page is for the Antagonists in Gurren Lagann.


[[folder:Thymilph the Raging Wave]]
->Voiced by: Creator/KiyoyukiYanada (JP), Creator/PaulStPeter (EN)

The first General Team Dai-Gurren faces. Thymilph is a ferocious and none too bright ape man. He's the most respectable of the generals, but also the deadliest. He pilots the Byakko, a powerful Gunmen that fires massive energy blasts, and owns the Dai-Gunzan, a massive walking fortress. Oh, and he's [[MinionShipping sleeping with]] [[TheVamp Adiane]].
* AFatherToHisMen: Was genuinely worried when Viral was sent flying.
** [[https://pp.vk.me/c614830/v614830493/a3b2/zklL7m1S-O4.jpg This image from one of the artbooks]] also suggests that Thymilph was this type of leader.
* AuthorityEqualsAsskicking: More powerful than grunts and Viral, he's the best at his introduction.
* BladeOnAStick: His Gunmen's weapon.
* TheBrute: Strong, big and a devil in a fight.
* CovertPervert: Watch carefully in episode 7 as Thymilph looks through six cameras. The very last one has an extreme closeup of [[AbsoluteCleavage Kiyoh's breasts.]] That [[Franchise/PlanetOfTheApes damn dirty ape!]]
* DropTheHammer: His personal side arm.
* FatBastard: A glutton with a mean streak as big as his battleship.
* EmergingFromTheShadows: His formal introduction.
* EverythingsBetterWithMonkeys: Not for Kamina, it isn't.
* HeroKiller: [[spoiler:He deals a fatal blow to Kamina.]]
* ImpaledWithExtremePrejudice: [[spoiler:Kamina and Simon GIGA DRILL BREAKER him.]]
* KarmicDeath: [[spoiler:Kamina stays alive just long enough to pay Thymilph back ''tenfold'' for spearing him- he ''purees'' him with his first (and only) Giga Drill Break.]]
* KnightOfCerebus: [[spoiler:Kills Kamina, which begins the series' more serious turn. Also to show that the Generals were tough as hell!]]
* LargeAndInCharge: The largest physically, and implied to the leader and strongest of the Four Generals.
* MeaningfulName: Thymilph is mix of thymine and sylph. Despite his girth he is ''very'' nimble and his Byakko can fly (though he isn't wind-themed, being the general of fire).
* OhCrap: His reaction to seeing Kamina deflecting his Condemn Glaize.
* PlayingWithFire: The General of Fire.
* PromotionToOpeningTitles: [[spoiler:Subverted. He appears in the new opening sequence of the Beastmen War Arc... which starts with the very episode following his death.]]
* ShoutOut: [[Franchise/PlanetOfTheApes "YOU DAMN DIRTY HUMANS!!!"]]
* UnholyMatrimony: There is implication that there may have been something intimate between him and Adiane. The manga of the series flat out states that the two were lovers.
* WakeUpCallBoss: [[spoiler:Kills Kamina and forces Simon to [[TakeUpMySword take up his sword]].]]

[[folder:Adiane the Elegant]]
->Voiced by: Creator/MichikoNeya (JP), Creator/MeganHollingshead (EN)

The psychotic [[TokenGirl female member]] of the Four Generals. Adiane is a scorpion-tailed temptress who tries avenging Thymilph's death. Viral has a secret crush on her, but she's such a violent monster that she doesn't acknowledge these feelings. She pilots Sayrune, a Gunmen that transforms into a scorpion, and uses an aquatic centipede flagship named the Dai-Gunkai. Unlike her fellow generals, she has the ability to make water appear out of thin air- and tons of it, at that.
* ArmorPiercingSlap: Viciously bitch-slaps Viral's face into a bloody pulp with her scorpion tail because she's angry he couldn't protect [[spoiler: Thymilph]].
* AuthorityEqualsAsskicking: Beats down the entire brigade, ''on land''!
** And effortlessly blocks all of Yoko's shots in the first movie.
* AvengingTheVillain: [[spoiler:Adiane used Thymilph as part of a plan to gain status amongst the generals, but it backfired when he died, and she's forced to take matters into her own hands.]]
* AwLookTheyReallyDoLoveEachOther: Adiane angrily declares she was sleeping with Thymilph to manipulate him. [[spoiler:But when she dies, she seems genuinely sad she didn't avenge him. Not the response of a manipulater.]]
** In the manga, as she is [[spoiler:about to die, she sees an apparition of Thymilph. She smiles, and the two hold hands until she's killed.]]
* AxCrazy: Kills people for shits and giggles.
* BeautyIsBad: The hottest of the Four Generals, and the bitchiest.
* BewareMyStingerTail: She is apparently a scorpion Beastman, though no other features appear.
* BloodKnight: Like other Beastmen, she loves fighting.
* CatFight: With Yoko in the first movie.
* DarkActionGirl: A very violent one.
* DarkChick: The most unstable of the four, she prefers to run into combat by herself, leaving her ship behind.
* DeathByIrony: She tried to avenge Thymilph's death, and was killed by his personal battleship.
* DualityMotif: The reason she wears an eyepatch. Her left eye is gold, while her right eye is red. She switches the patch around every now and then depending on whether she wants to look seductive or menacing.
* EyepatchOfPower: For no revealed reasons. See above. It also wraps around her entire body.
* HoistByHerOwnPetard: [[spoiler:Captures Nia and tells Team Dai-Gurren to point all of Dai-Gurren's cannons at Nia and open fire. Instead, Yoko shoots Nia free from Sayrune (after two Close Call Haircuts). Now all that firepower is aimed right at her. She tries to convince herself her enemy won't shoot... then Attenborough proves her VERY WRONG.]]
* HyperspaceArsenal: She can conjure up water inexplicably, in outrageous amounts to boot, whenever she wants.
* {{Irony}}: Like Viral, she's one of the more human looking Beastmen (seriously, remove the scorpion tail and she could easily pass for human), but is far more vocal about her anti-human beliefs.
* {{Jerkass}}: Not to the extremes of Cytomander, though.
* LadyOfWar: Shows herself to be a graceful fighter with her FemmeFatalons and scorpion tail. She's called [[LampshadedTrope Adiane the Elegant]] for a reason.
* MakingASplash: The General of Water.
** According to Parallel Works ''Kittan Zero'', Adiane actually has the unexplained ability to create obscene amounts of water out of thin air. That would explain the terrestrial locomotion of her Dai-Gunkai.
* MeaningfulName: Adiane is a combination of adenine and undine. Any guess why she shared a bond with Thymilph?
* MoralMyopia: Happily throws herself into this trope when Nia tries to get her to connect her rage over [[spoiler:Thylimph's]] death with Team Dai-Gurren losing [[spoiler:Kamina]], to no avail.
* MoreDeadlyThanTheMale: Much more violent and psychotic compared to the male Generals.
* NiceJobFixingItVillain: When Team Dai-Gurren first finds Nia, and after it comes out that she is the daughter of the Spiral King, they are distrustful of her. Then Adiane shows up and tries to break Nia's spirit before killing her by publicly announcing that Lordgenome thought of Nia as a doll and has cast her out and discarded her, ordering Adiane to kill her along with the rest of the humans. But when Team Dai-Gurren hears this, this causes them to trust Nia as Nia is now firmly on their side, and they're enraged at Nia being abandoned, to boot.
* PsychoForHire: A little unstable.
* ScaryScorpions: A tail, to be more exact.
* TheSmurfettePrinciple: The only female member of the Four Generals.
* SorryThatImDying: [[spoiler:In her final moments, Adiane regretfully asks Thymilph to forgive her for not being able to avenge him, and then gets torn to pieces by a gunfire.]]
* StatuesqueStunner: Adiane is ''enormous'', and completely towers over even Viral, who's over 6 feet tall already.
* {{Tsundere}}: A very dark version. She insists to Viral that she was playing Thymilph and gets angry at Guame for making insinuations about their relationship. However, there are several hints that she did care about him. [[spoiler:Her last words are an apology to him for failing to avenge his death.]]
* UngratefulBastard: Viral puts himself in harm's way to save her. She thanks him by beating him bloody. This is apparently par for the course for the Four Generals.
* UnholyMatrimony: With Thymilph.
* VaginaDentata: Her Gunman. It looks like a woman's torso as well.
* YouGottaHaveBlueHair: Though you could mistake it for black.

[[folder:Guame the Immovable]]
->Voiced by: Kiyoshi Kawakubo (JP), Doug Stone (EN)

Guame is the eldest of the four generals. The closest to the Spiral King, Guame doesn't worship him like the other Beastmen, and in fact was willing to disobey the man. Part alligator and part armadillo.
* AntiVillain: He was in on Lordgenome's agenda.
* BadassGrandpa: In a manner of speaking. He's about as old as Lordgenome, and thinks 200 years is still young.
* TheBattleDidntCount: Manages to survive a Giga Drill Break(er) in his first direct battle with Simon.
* BlindIdiotTranslation: The subtitles refer to him as "Guame the ''Immobile''".
* CoolOldGuy
* DeathIsDramatic: [[spoiler:Gave Lordgenome a farewell speech speared on Simon's drill, then got blown up in his crumbling battleship.]]
* TheDragon: To Lordgenome.
* DishingOutDirt: The General of Earth.
* DirtyOldMan: A highly disturbing one at the too. His actions with Nia are especially telling. He slobbers when he laughs.
* EverythingsBetterWithSpinning: [[spoiler:He summons a weird tornado of pink energy to guard Teppelin by rolling around on his shell.]]
* EvilCounterpart: Of Boota. [[spoiler:It's heavily implied Guame was Lordgenome's pet after going through Spiral Evolution.]]
* FallenHero: [[spoiler:Lost his resolve when Lordgenome lost his, and turned bitter and cruel.]]
* GoodSmokingEvilSmoking: The man smokes a rather ornate pipe, guess what? He's morally ambiguous!
* HoistByHisOwnPetard: First, he broadcasts his battle with Team Dai-Gurren to MakeAnExampleOfThem to the rest of humanity, only to lose in front of the whole world and fill other rebels with hope. [[spoiler:And in his fortress Gunmen, trying to crush Gurren Lagann only causes it to drill through faster, leading to his death]].
* ImpaledWithExtremePrejudice: [[spoiler:Simon drilled straight through his battleship from below, and the drill gored him right through his own shell and out the abdomen.]]
* MeaningfulName: Guame is a combination of guanine and gnome.
* NighInvulnerable: His battleship [[spoiler:survived a crash with Cytomander's and came out unscathed.]]
* NonActionGuy: He doesn't have Viral's skill in a fight, Thymilph's strength, Adiane's balls-out craziness, or Cytomander's willingness to cheat. He is the smartest of the four, however.
* TheStrategist: Relies on his brains rather then his Gunmen.
* TeamPet: Was once this to Lordgenome, until evolution turned him into a snobbish and revolting codger.
* UpliftedAnimal: [[spoiler: If it really was him in the Parallel Works that reveals Lordgenome's backstory, then he's not even actually a Beastman and is instead an animal that evolved rapidly due to excess exposure to Spiral Power. He may even ''have Spiral Power himself''.]]
* VaguenessIsComing: Makes references to humanity's "true" enemy and how Spiral power will doom them, but never provides specifics. Somewhat in that he's speaking either to himself or Lordgenome, so the details aren't actually needed.

[[folder:Cytomander the Swift]]
->Voiced by: Akio Suyama (JP), Creator/SteveStaley (EN)

The incredibly fey air general. Cytomander is a bird man with a serious ego. Guame chastises him for being too brash, and when he's on the losing side of a battle, the guy [[AxCrazy ''really'' flips his lid.]] His personal Gunmen is Shuzack, and his flagship is the Dai-Gunten.
* AgentPeacock: He is incredibly fabulous but he owns perhaps the most powerful General fortress in the series. Also literally a peacock man.
* AxCrazy: The moment he loses his edge in battle, his sanity wears down to vapor-thin until, finally, he's LaughingMad.
* {{Bishonen}}: He's very pretty.
* BlowYouAway: The General of Air. He even seems to be able to teleport using air.
* CurseCutShort: [[spoiler:When he sees the massive Dai-Gurren thundering right towards his Shuzack.]]
* BreakTheHaughty: His calm behavior turns less and less calmer as he begins to lose.
* CombatPragmatist: Captures Yoko so Viral could kill Simon. It [[HonorBeforeReason doesn't work]].
* ChainsawGood: Uses a buzzsaw as his weapon.
* EvilGenius: Notices Team Dai-Gurren's weakness, and capitalizes on it.
* FeatheredFiend: He appears to be a peafowl-man hybrid.
* {{Jerkass}}: The biggest among the Four Generals, and arguably the biggest in the series.
* LaughingMad: When the tide of battle turns against him it drives him crazy and this happens. It's bad enough that it almost ''mirrors'' a trollface.
* MeaningfulName: Cytomander is a combination of cytosine and salamander. Him being a flashy peacock parodying Japanese glam rock has more to do with his mecha's theme; it's named Shuzack, after ''Suzaku'', a mythical bird in Japanese folklore.
* NonActionGuy: Only wins fights through cheating.
* SissyVillain: Gigantic boa? Rainbow colored lights? Stands on a stage wearing a [[PaintedOnPants body suit]]? Yes.
* SmallNameBigEgo: "Maybe it's not that they're so weak, it's that I'm too powerful!" *laughs manically* [[spoiler:Now, watch as I get my ass handed to me, go insane, and die!]]
* SmugSnake: Spends his time insinuating that the other generals are incompetent, it doesn't work out.
* SpellMyNameWithAnS: His name is pronounced "Cytomandra" in the English dub.
* SuicidalOverconfidence: [[spoiler:His brimming overconfidence finally gets him killed when Team Dai-Gurren rams him with their battleship prow, sending him crashing into the Dai-Gunten, where both it and he are obliterated in the carnage.]]
* UngratefulBastard: As with Adiane, Viral saves his life, and as with Adiane, Cytomander declares he's going to horribly punish Viral, who just seems to take it in stride by now. Unlike Adiane, Cytomander is rather understandably pissed at Viral for putting [[HonourBeforeReason his honour before Cytomander's victory.]]
* VillainousBreakdown: When his ass is getting kicked he laughs crazily. [[spoiler:At the point of his death, he's pretty much gone completely insane.]]
* WeHaveReserves: Horrifies Simon with his willingness to get his own men killed. [[EvenEvilHasStandards This makes even the other three generals hate him.]]

->Voiced by: Narushi Ikeda (JP), Creator/JamiesonPrice (EN)

Lordgenome is the ominous Spiral King who rules the planet from his capital city, Teppelin. An immortal human who lived for more than 1,000 years so far, he cares little for people, treating the strange girls he surrounds himself with as dolls to be cast aside when they've outlived their interest to him.
* AGoodWayToDie: [[spoiler:The second time.]]
* AbusiveParent: Just from his treatment of Nia and implications that he let all of his other daughters die on a whim. Outright confirmed in the anime when a whole graveyard of similar capsules is found by Team Gurren. [[spoiler:If not for the presence of the Anti-Spiral, his trying to kill Nia could be considered a MoralEventHorizon if he hadn't crossed that already with all the other children he's had killed.]]
* AmbiguouslyBrown: Though his outfit and facial features suggest he might be of Turkish or Middle Eastern ancestry. His Parallel Works, however, show that he was light-skinned when he was younger.
* AntiVillain: [[spoiler:While his methods can be pretty brutal, the fact is that Lordgenome oppresses the human race to ''preserve'' it. Having faced the Anti-Spiral before, Lordgenome knows that, if unchecked and left to develop and reproduce, the human race would once again get noticed by the Anti-Spiral, which would spell its complete and utter destruction, and even if they beat the Anti-Spiral, they will cause the universe to implode. He keeps the humans backward and living in fear because the alternative is much, much worse. And after the TimeSkip, his worst fears become realized... except the human race will not be getting annihilated, because the heroes are just that awesome.]]
* AuthorityEqualsAsskicking: And don't you forget it! There's a reason all the militant beastmen obey him without question.
* AwesomenessIsVolatile: It makes you head catch fire!
* BackFromTheDead: [[spoiler:Kinda. Sorta.]]
* BadassArmFold: ''Never'' uncrosses his arms while fighting in Lazengann (unless he's doing a LimitBreak).
* BadassBaritone: Especially in the dub.
%%* BaldOfAwesome
%%* BaldOfEvil
%%* BadassBeard
%%* BeardOfEvil
* BigBad: [[spoiler:For the first arc.]]
* BrainInAJar: [[spoiler:Spends most of the time following his death this way, but briefly regains his body just before the ending.]]
* BloodKnight: If making one of your servants strong enough to test your number one enemy doesn't count, then coming out of your Gunman just to beat with your fists while laughing maniacally does.
* CarpetOfVirility: Starts out normal, but when Lordgenome [[HotBlooded gets really fired up]] it becomes a spiral shaped one!
* ColorCodedWizardry: His Spiral Power glows red as opposed to the usual green. What this exactly entails is the source of much debate.
* ADayInTheLimelight: The last Parallel Works video, which serves as a prequel telling his StartOfDarkness.
* DarthVaderClone: [[spoiler:They were once heroic knights fighting for justice, but were driven by the BigBad to make a FaceHeelTurn and become [[AntiVillain Anti-Villains]]. Oh, and they both make a HeroicSacrifice to save TheHero from the BigBad]]. To drive the point home, Lazengann is covered in black armor, just like Vader, and he's the ArchnemesisDad to Nia.
* DidntSeeThatComing: He's ''very'' surprised that Simon has a Core Drill [[spoiler:which he uses to kill him]].
* DiscOneFinalBoss: [[spoiler:After the first arc, the Anti-Spirals take his place.]]
* DyingMomentOfAwesome: [[spoiler:Twice!]]
* EleventhHourRanger: [[spoiler:He regains his body and joins the Tengen Toppa Gurren Lagann in the climax.]]
* EmperorScientist: Presumably how he took over the world. He knows how to create Beastmen and their gunmen.
* EvilCounterpart: To [[spoiler:Simon, which is pointed out when Viral calls him "usurper of Lordgenome's throne"]].
* ExoticEyeDesigns: They're spiral-shaped, a trait shared by the Lagann in one instance, [[spoiler:Kittan in his Heroic Sacrifice]], the Super Tengen Toppa Gurren Lagann, and [[spoiler:Simon in the epilogue]].
* TheExtremistWasRight: Thanks to his actions, [[spoiler:Earth was kept safe from the Anti-Spiral for nearly a millennium]]. Yes, his rule was oppressive, but it was better than [[spoiler:the planet's destruction]].
* FallenHero: [[spoiler:Tried to overthrow the Anti-Spirals pre-series but was vanquished and became an oppressor of mankind like the Anti-Spirals he fought against.]]
* FlamingHair: That's sheer spiral power there.
* HeelFaceRevolvingDoor: [[spoiler:Starts out as a Spiral Warrior fighting the Anti-Spirals, does a FaceHeelTurn and]] takes the role of the BigBad at the beginning, [[spoiler:takes a neutral role as the Biocomputer, and finishes how he started]].
* HeelFaceTurn: [[spoiler:After he is brought back to life.]]
* HeroicSacrifice: [[spoiler:LAZENGANN! OVERLOAD!!!]]
* GeniusBruiser: Genetic engineer, master computer hacker, really beefy ''and'' able to beat up a mecha with his bare hands. Definitely qualifies.
* HotBlooded: So much so that he ''ignites his own head''.
* IAmNotLeftHanded: [[spoiler:After Lazengann is defeated, he starts overpowering Gurren Lagann by beating it using raw strength alone]].
* IncendiaryExponent: Tends to catch on fire when he does awesome things, [[spoiler:such as beating up a mecha with his bare hands, or doing interstellar travel by foot]].
* IWasQuiteALooker: We see in the last Parallel Works video that he used to basically be a male version of Nia.
* TheLastDance: [[spoiler:Twice!]]
* MeaningfulName: Lord'''genome''' genetically engineered the Beastmen. Including the Four Generals, which adds another layer of logic to their "DNA base + alchemical spirit" based names.
** Also, [[spoiler: he was one Spiral Knight and the DNA helix, where the genes are localized, is in spiral format]]
* MrExposition: He becomes this after becoming the Bio-Computer for Team Dai-Gurren. Any information involving Spiral Energy, the Anti-Spirals, the War against the Anti-Spirals, and scientific phenomenon is explained by him.
* NonstandardCharacterDesign: Unlike most of the characters, he's given a more... Let's call it ''traditional'' Anime Muscular Man look.
** Doubles as UncannyValley.
* OffhandBackhand: When Simon ejects Lagann to use just it against Lazengann, Lordgenome gives Rossiu an annoyed "go away" before slapping Gurren to the ground with his tail.
* OhCrap: [[spoiler: When he realizes that Simon has just slammed the [[CoolKey Core Drill]] into his chest. You know, the thing filled with enough spiral energy to power Gurren Lagann.]]
* OneManArmy: [[spoiler:Goes against the entire Spiral Army and ''wins''.]]
* OneManIndustrialRevolution: As shown in the last Parallel Works Video, Lordgenome was the forerunner and inventor of a number of scientific marvels utilized by humanity in their war against the Anti-Spiral. These achievements ranged from aerospace engineering and spacial-temporal travel to genetic engineering.
%%* OracularHead
* RatedMForManly: Probably the manliest of all the characters, and [[WorldOfBadass that is really saying something]]. Just an "M" might not even cut it.
** To put it simply: He pilots a jet black mecha, [[spoiler:which is weaker than him]]. [[spoiler:He considers using it ''holding back'']]. His idea of [[spoiler:hacking is running through cyberspace and bashing boxes with his head]]. He [[spoiler:''eats an attack with the power of '''the Big Bang''' and uses it to turn into a drill'']].
* RoyalHarem: One of the many ways he passes the time is having sex with his personal harem made of young girls kidnapped and trained for servitude in Beauty Village and sent by Guame. From these concubines, Lordgenome has spawned countless children (Nia included) that he raises and later discards on a whim. The concubines also act as a BattleHarem by becoming drills for his Lazengann.
* ReallySevenHundredYearsOld: He doesn't look like it, but he's at least over 1,000 years old.
* RedemptionEqualsDeath: [[spoiler:Becomes a good guy and then dies to provide an opening for the rest.]]
* SocialDarwinist: [[spoiler:Subverted at least at the end.]]
* SpellMyNameWithAnS: Is it Lord Genome or Lordgenome? Or even Lord Lordgenome?
* SpiritualAntithesis: To [[Anime/NeonGenesisEvangelion Gendo Ikari]]. Both {{Tragic Villain}}s are older males who serve as the ArchnemesisDad to one of the series' protagonists, engineered the life of a blue-haired MysteriousWaif,[[note]]the same character as the child in Lordgenome's case,[[/note]] have [[DarthVaderClone loose similarities to Darth Vader]] of ''Franchise/StarWars'', [[spoiler:and secretly have WellIntentionedExtremist motives]]. However, while Gendo was more of TheChessmaster and never engaged in direct combat, Lordgenome puts up a spectacular fight once Simon reaches his stronghold. Both characters also reflect the protagonists of their respective series, reinforcing their opposite nature: Gendo, while masculine with an air of coolness, isn't notably manly [[spoiler:because he's essentially what his cowardly son Shinji would be if he grew up]], while Lordgenome is one of the manliest characters in the show [[spoiler:and was a lot like adult Simon in his youth]]. Furthermore, in the end, [[spoiler:Lordgenome pulls a HeroicSacrifice, while Gendo continues trying to go through with his plan only for Rei to betray him]].
* StartOfDarkness: The last Parallel Works video, which is also the only canon one.
* StatusQuoIsGod: [[spoiler:A literal example. He lost his own war against the Anti-Spiral, so he had to put himself in a position to ensure that they don't exterminate humanity. He forced the human race underground and kept them under a safe number so the probes of the Anti-Spiral don't react to exterminate the race. He then got rid of the probes as soon as they start to gain sentience and killed every human that tried to go to the surface. It's implied that he did this for hundreds if not thousands of years]].
* StrongFamilyResemblance: to [[spoiler:Nia]] [[IWasQuiteALooker At least when he was younger.]]
* StrongFleshWeakSteel: During his fight Simon, [[spoiler:he ends up breaking Gurren and turns Lagann into a broken mess. He's ultimately killed when Simon impales him with his Core Drill.]]
* TechnoBabble: Once he was so incomprehensible that even [[TheSmartGuy Leeron]] didn't understand him.
* TorsoWithAView: [[spoiler:After being impaled by Simon's Core Drill. This somehow doesn't prevent him from talking.]]
* TragicHero: [[spoiler:Was originally the heroic Spiral Knight of the Galaxy, before the Anti-Spiral showed him the truth of the Spiral Nemesis. After that, and also realizing the undefeatable nature of the Anti-Spirals, he cuts his losses and becomes a WellIntentionedExtremist, slays all of his Spiral comrades, and becomes a brutal tyrant to keep the human race alive.]]
* TranquilFury: During his fight against Gurren Lagann, he attacks quite ferociously, yet maintains a stoic face and voice, as well as his BadassArmFold. [[spoiler:He only starts to show hamminess when he activates Lazengann's LimitBreak; after that, during his fistfight with Lagann, he goes into full BloodKnight mode.]]
* UseYourHead: In the second compilation movie. When it comes to hacking, there's the realistic way, there's the HollywoodHacking way, and then there's the Lordgenome way, in which one plugs in and physically beats the security system into submission with one's forehead.
* VillainTeamUp: He [[http://www.youtube.com/watch?v=O1lzW2zP71E meets with Gaiou before Scenario 44]] on the Earth route and receives two Dino DAMON in exchange.
* VillainousBreakdown: Subverted, instead of having a freak out, he begins to enjoy the hot blooded excitement of his battle with Simon, as he once experienced [[spoiler:when he fought the Anti-Spirals.]]
* WalkingShirtlessScene: He has nothing on under his robe to cover his uber-muscular physique.
* WellIntentionedExtremist: Maybe. [[spoiler:He enjoys his fight with Simon a little too much.]]
* ZenSurvivor: Made bitter by [[spoiler:his defeat at the hands of the Anti-Spirals]], he doesn't tell anyone what he's learned and warns them only in a cryptic sense.

!!The Anti-Spiral
[[folder:The Anti-Spiral]]
-> Voiced by: Takaya Kamikawa (JP), Dave Mallow (EN)

-> ''"You seek beauty in struggling to the bitter end- a trait instinctive to those bewitched by the power of the Spiral... Nevertheless, that is an act which has been repeated time and time again. Now, follow the same fate as those Spiral Warriors... WHO CAME BEFORE YOU!!"''

The ultimate BigBad of the series. This bizarre being appears to be the embodiment of the collective mind and will of the Anti-Spiral race. As he resides in AnotherDimension created by the Anti-Spirals, he has near-infinite levels of power, up to and including manipulation of the very laws of nature.
* AbsoluteXenophobe: [[spoiler: Wants ALL forms of life gone or at least incapable of evolving to prevent the Spiral Nemesis from coming to pass, and by hell or high water, he makes sure of it.]]
* AFormYouAreComfortableWith: Sort of. He agrees to fight the protagonists [[LetsFightLikeGentlemen "on your own terms"]], meaning the EvilKnockoff [[spoiler: mecha]] mentioned below. His reason for doing so, however, is not to relate to them, but rather to humiliate his opponents by defeating them in a MirrorMatch rather than simply [[RealityWarper Reality Warping]] them into nonexistence. He does this because if he assumed a form more powerful than them, they would simply Spiral Power their way up to his level, so limiting his own power in effect limits theirs as well. Additionally, he considers that defeating an opponent slowly and on their own terms generates more despair, which is what he's after.
* AliensAreBastards: To borderline monstrous extremes. And the worst part is [[spoiler: he's convinced [[KnightTemplar he's the good guy]] even after crossing the MoralEventHorizon over and over and over again]].
* ArtShift: In TheMovie, [[spoiler: he shifts from "Skinny" to "Uber Muscular" a few times, also gaining a more versatile expression range that borders on NightmareFuel when he smiles deviously]].
* BaldOfEvil: Lacks hair, but then again, he lacks pretty much any other features as well aside from vague eyes and a mouth, pretty much doing the bare minimum to even resemble a human being.
* BlankWhiteEyes: His ''default'' expression.
* BigBad: Of the entire series, although it doesn't show up until after the TimeSkip. During the Beastmen Arc, it was effectively TheManBehindTheMan, since Lordgenome's plan to keep humans living underground also benefited its goal.
* BigNo: Along with RapidFireNo and BigNever [[spoiler: During the final battle.]]
* BoomerangBigot: [[spoiler:The Anti-Spirals use to be Spiral beings themselves.]]
* CombatTentacles: They are typically drill-shaped, similar to the Lazengann's drills.
* DeityOfHumanOrigin: Sort of. [[spoiler:A HumanoidAbomination created by someone, instead of more traditional cosmic god.]]
* DesperationAttack: [[spoiler:Uses his tentacles to shred Lagann as it descends on him, but cannot stop it in time. In '''Lagann-Hen''', he does, but Simon himself begins a one-on-one fistfight moments later.]]
* CreepyMonotone: Speaks with an unnerving calm, at times making him sound like a scientist who is merely conducting an experiment rather than [[spoiler:a SufficientlyAdvancedAlien with incredible power.]] By the final battle, [[spoiler:however, he's ranting a mile a minute and shouting attack names just like everyone else.]]
* DickDastardlyStopsToCheat: [[spoiler:Being a RealityWarper, he could probably have erased the Spiral team in seconds when they entered his realm. However, his modus operandi has it that to inflict absolute despair, he has to first provide a glimmer of hope, meaning that he '''wants''' to defeat the team on their own terms.]]
* DimensionLord: He resides in his own universe.
* EvilCannotComprehendGood: "We have no need to understand. We only need to know." [[spoiler: Rather suspect considering the Anti-Spiral itself is a Spiral Race, meaning it shares too much in common with the heroes to truly be unable to understand them.]]
* EvilFeelsGood: Despite claiming he/they have no emotions, they seem to enjoy inflicting [[DespairEventHorizon Absolute Despair]] on their enemies.
* EvilKnockoff: [[spoiler:In response to the heroes' advance, he creates a twisted version of their own mecha, and even fights using drills during the climax. In the second movie, this includes his own version of the Giga Drill Breaker.]]
* TheEvilsOfFreeWill: Though that's a ''little'' bit more justified when the force that is and is created by free will and makes free will possible is what is fueling entropy.
* FaceDeathWithDignity: [[spoiler:When he's killed, his last words are "If this is how it must be, [[TakeUpMySword protect the universe at all costs]]."]]
* FantasticRacism: [[spoiler:[[WellIntentionedExtremist Well Intentioned Extremism]] not withstanding, he absolutely deplores and hates other spiral races, considering them reckless fools who need to be restrained. See AbsoluteXenophobe. However, he does seem to have relented in this in his final moments, having asked Simon to protect the universe.]]
* FatalFlaw: [[spoiler:{{Pride}}. He is so confident that he toys with enemies instead of crushing them with his full godlike power, which proves to be his downfall.]]
* FinalExamBoss: Fighting him involves attacks and weapons used by multiple Spiral Warriors, as well as every version of Gurren Lagann (with Lagann, by itself, delivering the final blow).
* GoodOldFisticuffs: Believe it or not, unlike most [[PhysicalGod divine-level]] aliens he's ''not at all'' above getting down and dirty with his bare fists.
* GreaterScopeVillain: Of the Lordgenome arc
* HeroKiller: Part of the Anti-Spiral's backstory is that he's killed countless Spiral warriors before. He tries to break Team Dai-Gurren by rubbing in their face the fact that making it to his dimension does not make them special. He fails, of course. Of the main group, he does kill [[spoiler:Kittan]] and possibly many minor characters who were all heroes in their own right (depending on whether you're watching TheMovie or not). Also, while he didn't kill Lordgenome, he did '''break''' him.
* [[HiveQueen Hive King]]: Subverted. Although often known in fandom as the Anti-Spiral King, he's not actually a ruler but a [[HiveMind collective avatar]] of the entire Anti-Spiral race.
* HopeCrusher: His main method of eliminating spiral energy (which is derived from hope and courage) by destroying their opponents HopeSpot before snatching victory in the cruelest and unfair way possible to destroy their will to fight.[[spoiler: He does this because he knows that despair is the only way to truly stamp out Spiral Power and thus the Spiral Nemesis.]]
* HotBlooded: [[spoiler:He can claim that the Anti-Spirals discarded all of their emotions all he wants; he nearly matches Simon in this respect during the final battle.]]
* HumanoidAbomination: [[spoiler:His NonstandardCharacterDesign gives him this vibe, rather than seeming human in his own right, he ends up looking like something from the game Videogame/EarthBound, not as frightening as Giygas, but the way the Anti-Spiral looks makes it seem as if he's "Out of Sync" with reality, which, in a manner of speaking, he is.]].
* {{Hypocrite}}: [[spoiler:As noted above, the Anti-Spiral is quick to abandon his vaunted stoicism in the final battle.]]
* JumpingOffTheSlipperySlope: When the Anti-Spiral race discovered the possibility of the Spiral Nemesis, rather than theorize on ways to slow it or lessen Spiral Energy consumption they instead jumped straight to removing their own capacity for it and then to ''genociding literally every other Spiral Race in existence.''
* KamehameHadoken: [[spoiler:Uses a Big Bang this way... [[NotMakingThisUpDisclaimer No, you did not misread that.]]]]
* KnightOfCerebus: Even when Thymilph and Lordgenome darkened the show, there was still enough lighthearted and playful humor. Come the timeskip and ''this guy'', things become even less amusing and [[DarkerAndEdgier much darker]].
* KnightTemplar: [[spoiler:His goal is to prevent TheEndOfTheWorldAsWeKnowIt from occurring. All fine and well, if not for the fact that his means of doing so are so draconian [[FateWorseThanDeath that they defeat the purpose]].]]
* LargeHam: [[spoiler:Yes, even in his more quiet moments, he's still a ham.]]
* LetsFightLikeGentlemen: [[spoiler:Despite having almost enough power to curb-stomp the heroes (the exact limits of his power are unknown, and may even be infinite), he always takes the form of his enemy, with just a ''tad'' more power, to demoralize his enemies and make them lose spiral power. When the heroes take the form of the Super Tengen Toppa Gurren Lagann with the help of a Big Bang, the Anti-Spiral matches it by ''breathing'']].
* LossOfIdentity: Purging themselves of Spiral power and stopping their own evolution resulted in their entire race becoming blank beings with no clear identity.
* MasterRace: Deconstructed: [[spoiler:They conquer the universe for the sake of their own existence]].
* MindHive: [[spoiler:The so-called "Anti-Spiral King" is the collective psychic embodiment of the Anti-Spiral Race.]]
* NonstandardCharacterDesign: He is drawn as a vaguely-human black silhouette, with very simple white eyes and mouth. This helps illustrate his alien nature.
* NotSoDifferent: Inverted. Anti-Spiral Nia says that nobody could suppress the Spiral Instinct (read: LargeHam {{Hotblooded}}-ness) indefinitely, and she was right.
* OrderVersusChaos: The Order to Team Dai-Gurren's Chaos. Showcased in it's rather bland and lifeless mechs it sends against the group as well as the fact they're all interchangable from each other. Even Lordgenome's forces had more personality and a bit of fun to them.
* OmnicidalManiac: Deconstructed: [[spoiler:The Anti-Spiral are paranoid of a mother-of-all-apocalyptic nightmare erasing all creation ever known and decided to suppress all other lifeforms to ensure it will never happen.]]
* TheOmnipotent: He has complete control of his pocket universe, even able to manipulate probability. The only reason he doesn't just annihilate the heroes is due to gaps of information.
* RealityWarper: Can alter probability: the force of nature that sets forth the laws of reality. That would make the Anti-Spirals the equivalent of first-order beings. The next step up from that is ''{{God}}.''
* RedEyesTakeWarning: [[spoiler:His eyes have flickering splotches of red as he anaylzes Nia.]]
* RoyalWe: Justified, as he's a MindHive speaking for his entire species.
* SlasherSmile: [[spoiler:A very sickening one whips across his face as Simon dashes toward him with a drill arm in ''Lagann-Hen''.]]
* SufficientlyAdvancedAlien: Perhaps even Perfectly Advanced Alien. Ironically, [[spoiler:Anti-Spirals have evolved so far, they stopped out of fear it would unravel creation itself.]]
* ShadowArchetype: [[spoiler:Just as the protagonists are trying to keep their race alive and are very determined to do so, the same is true for the Anti-Spiral race, which he [[LampshadeHanging points out]] as part of his BreakingSpeech during the final battle.]]
* TechnoBabble: Has a few shades of this.
* UnmovingPlaid: Adding to his inhuman feel.
* VillainousBreakdown: [[spoiler: He really blows his stack when Team Dai-Gurren refuse to give up and keep getting stronger, to the point of [[GodzillaThreshold using more Spiral Power to compensate]] despite knowing how dangerous that is.]]
* WalkingSpoiler: His appearance reveals the cryptic warning that Lordgenome left the heroes, which reveals much of his motivations, as well as the existence of the Beastmen and the reason he oppressed humanity.
* WellIntentionedExtremist: [[spoiler: In the end, what he is trying to do is ensure the universe's survival, however, he's totally freaking NUTS in the way he goes about it. However, one could [[AlternativeCharacterInterpretation interpret]] his actions as not coming out of a desire to protect the universe, but to protect ''[[ItsAllAboutMe himself]]''. It would certainly fit with how much of an AbsoluteXenophobe the guy shows himself to be, and how he's willing to [[OmnicidalManiac kill every other living thing in the universe]] to do so. After all, what good is a universe without any life existing in it? Still, he accepts defeat well, and did let a very, very, very limited humanity survive for a time (so it is not ALL life).]]

!!The Spiral Nemesis
[[folder:The Spiral Nemesis]]

An apocalyptic force that is said to occur when the universe's Spiral Power goes out of control.
* AmbiguousSituation: One of the greatest questions spawned by debates over it is "Does it even exist?" The answer will most likely never be revealed.
* ApocalypseHow: a Universal one at that. If it ever occurs, that's it, everything's done.
* GreaterScopeVillain: If it is [[SentientCosmicForce sentient]] then it is this, though it's equally possible that the Spiral Nemesis is simply a naturally occurring event, in response to overuse of Spiral Power.