'''Dr. Caroline Todd'''
* AlwaysSomeoneBetter: First it was Angela, then briefly Holly until she showed her true colours.
* BelligerentSexualTension: With Mac, before they get to know each other.
* BornUnlucky: Her first day at the hospital sums this up nicely. She is locked out of her brother's house and has to sleep in her car, Joanna pulls her hair (to "see how well she deals with stress"), everyone keeps asking her why she smells funny, "Have you been to a festival?", "What's that smell? Is that...is that mini-cabs?" Sue gropes her arse, she hears Angela telling Martin to do horrible things to "the new girl" ([[ItMakesSenseInContext because Mac told her to try being jealous]]) Guy persuades her to come stay at his flat and so everyone assumes she slept with him when she didn't. And then there's what happens to her during the rest of the series...
* BoyishShortHair
* {{Buttmonkey}}
* DeadpanSnarker
* DidIJustSayThatOutLoud
* DudeMagnet: Despite her social awkwardness, 70's clothes and [[BoyishShortHair masculine haircut]], manages to attract Mac, Guy, Martin and Jake, although it's obvious she is only truly interested in Mac.
* INeedAFreakingDrink
* ImplausibleDeniability: Tends to lie, then awkwardly attempts to bluff her way through it, which rarely works. Her worst attempt was claiming the, ahem, ''outfit'' she had on to "surprise" Mac with when Mac came home with Holly and Mackenzie in tow was what she planned on wearing for dinner with her "Uncle".
* ItsAllAboutMe: Mac views her as this when she first arrives at the hospital. While it's certainly nowhere near that extreme, she can be quite self-centered, like when Martin was trying to tell her [[spoiler: He has a half-brother]], she's more interested in finding a way to stop Mac from moving to Sheffield.
* LooseLips: Probably shouldn't have told Sue White that she had feelings for Mac.
* [[NiceGuy NiceGirl]]: Despite occasional moments of stubbornness or self-centeredness, she's one of the nicer characters on the show and tries to be helpful towards others.
* TomboyAndGirlyGirl: She's the tomboy to Angela's girlygirl.
* [[spoiler: UnbalancedByRivalsKid]]: [[spoiler: Subverted- Holly tries her damndest, but Mackenzie is not actually Mac's kid.]]

'''Dr. "Mac" Macartney'''
* BadassBiker: Has a motorbike, which he keeps in one of the lifts in the hospital. He also likes to drive around on it naked.
* BelligerentSexualTension: With Caroline, at least when they first meet.
* BewareTheNiceOnes: Do NOT piss him off, as Guy found out the hard way.
* ChickMagnet: He is universally adored, admired, and lusted after by almost everybody at the hospital with little-to-no effort on his behalf. He spends the series being chased down by Caroline, Emmy, Holly and of course, Sue White.
* DeadpanSnarker
* DuckSeasonRabbitSeason: Mostly used on Guy and Alan, but he sometimes does this to Caroline.
* TheGadfly: He really likes to mildly annoy people, although they are usually people who need their ego bruising a bit, mainly [[SmallNameBigEgo Guy]], [[BadBoss Joanna]] and [[OldWindbag Alan.]]
** Does it to Caroline too, although it's more flirting than aggravating.
* GratuitousFrench: [[MundaneUtility Mostly uses it to annoy Guy]].
* HeterosexualLifePartners: With Guy.
* HospitalHottie
* InsistentTerminology: He is not ginger, he is blonde.
* LiteralMinded: Often pretends to be to confuse/irritate people.
* MenDontCry: Mac successfully restrains himself from turning on the waterworks, even in the full knowledge that [[spoiler:he's dying of an incurable disease and that he'll never marry, have children and live a full life]], as a sobbing Martin Dear blubbers out to him.
* NervesOfSteel: Mac is usually very composed in dangerous situations, the best example being when he tries calming down a hysterical Guy in the Season One finale.
* NiceGuy: His habit of irritating people aside, he is a genuinely kind, compassionate person. He looks after a very-drunk Caroline, constantly steps in when Guy's bullying of Martin goes too far and is generally pretty friendly.
* NiceToTheWaiter: Mac seduces the dinner ladies with genuine charm and compliments, and effortlessly strikes good friendships and rapport with the janitors.
* NoNameGiven: Dr. 'Mac' Macartney. Lampshaded and [[TheUnreveal unrevealed]] variously throughout the series, especially when he is looking at his medical test results:
--->'''Dr. Macartney''': Sometimes I forget I have a first name.
* NoSparks: With Emmy.
* OnlySaneMan
* TranquilFury: Casually stabs Guy in the arm when he teases him one too many times about Holly.
* VitriolicBestBuds : With Guy.
* WhatTheHellHero: Invoked by Caroline, when she eventually confronts him about his mixed messages.

'''Dr. Guilaume "Guy" Secretan'''
* AllMenArePerverts
* AnalogyBackfire
* AnimalMotifs: Several people reference the fact he looks like a donkey. (Specifically the one from Shrek.)
* BigOlEyebrows
* TheBully/[[spoiler: BigBrotherBully]]: Mainly to Martin, but he's also seen harassing other members of staff if he's bored.
* TheCasanova: He blurs the line between Casanova and KavorkaMan but is more of the former.
** Parodied when he reels off a long-winded, sorrowful cock-and-bull story in an attempt to hit on Joanna, who laughs at him for it (but still sleeps with him anyway).
** Subverted with his later undying love and failed attempts for Caroline, which drops him down to a CasanovaWannabe.
* CharacterDevelopment: One of the most prominent examples in the series.
* DoesNotKnowHowToSayThanks
* EmbarrassingMiddleName: [[spoiler:Valerie]].
* TheFriendNobodyLikes: On occasion.
* HilariouslyAbusiveChildhood: Implied, especially as he apparently went to a boarding school at a young age and the memory reduces him to snivelling to himself in the cloakroom.
* HeterosexualLifePartners: With Mac.
* HospitalHottie
* InferioritySuperiorityComplex: If you look underneath his arrogant alpha male bravado, it's clear he's actually quite insecure and pathetic.
* JerkWithAHeartOfGold: Eventually.
* MenDontCry: Subverted and lampshaded by Sue White when she catches Guy crying like a sissy in the cloakroom.
* TheNicknamer
* ReallyGetsAround: [[UpToEleven Even Naughty Rachel calls him a slag.]]
* UnresolvedSexualTension: With Sue White.
* StrongFamilyResemblance: [[spoiler: Guy and Martin, since they are half-brothers.]]
* UnsympatheticComedyProtagonist
* VitriolicBestBuds : With Mac.

'''Dr. Alan Statham'''
* AxCrazy: He psychotically [[spoiler: beat a dwarf to death with a stuffed heron]].
* BadLiar: Most of the time he can't even get to the actual lying stage, and ends up blurting out the truth instead.
* BiTheWay: He clearly has a [[BelligerentSexualTension crush]] on Boyce, despite the fact that he is simultaneously infuriated by him.
* CrazyJealousGuy: Becomes very antagonistic towards Lyndon because Joanna flirts outrageously with him, but he seems oblivious to the fact that Lyndon finds Joanna "disturbing". [[FridgeLogic Or maybe he just doesn't want to acknowledge Joanna doesn't really like him that much.]]
* GeniusDitz: He is totally useless at basic social interactions and doesn't understand at first what Joanna means when she tells him she's "late" and offers to call her a taxi, but he does work in a hospital and is a consultant.
* HeroicBSOD: Has one after Joanna dumps him, leading to him stealing a milkvan.
* KavorkaMan: He is known to have had several sexually-charged conquests throughout his lifetime, despite being completely and utterly devoid of personality, looks, charm and even the most basic social skills.
--->'''Dr. Alan Statham''': Surreptitiously however, I was bringing her to climax with a breadstick...
** The woman he stalks at the hospital chapel is obviously repulsed by him.
* LargeHam
* MotorMouth: Particularly when upset.
* ScreamsLikeALittleGirl
* SesquipedalianLoquaciousness: He often speaks in ridiculously complicated sentences and vocabulary, and sometimes even resorts to French and Latin just to express himself.
* TheUnintelligible: One episode has Alan deciding he wants to be part of a council, so asks Sue White for advice. She promptly tells him to get a voice coach because he "sounds like a hysterical child that's swallowed a conker!"
* OldWindbag
* OutlawCouple: With Joanna in the special. Most of the crimes they commit, though, are really due to their own stupidity.
* UnsympatheticComedyProtagonist


'''Dr. Martin Dear'''
* [[spoiler: AnnoyingYoungerSibling]]: To Guy.
* BiggerIsBetterInBed: Sue discovers this about Martin in one episode, complete with oil painting.
** Although she never actually sleeps with him.
* BumblingSidekick
* {{Buttmonkey}}
* CasanovaWannabe: Martin is the polar opposite of Guy in every way, a relatively unpopular, socially awkward and rather dumb individual who spends the series in totally unrequited love with Caroline. Rachel's pet nickname for him is "Martin Dear, he's so queer!"
* ClarkKentOutfit: In the episode where he poses for a life drawing class we see that he's actually rather ripped.
* TheDitherer
* DoggedNiceGuy: Shows elements of this to Caroline, even when he takes her on a date and all she can do is talk about Mac.
* EmbarrassingNickname: Common nickname for Martin is "Fartin." He also goes into a very lengthy anecdote to Caroline about how he came to be known as "Titbrain" at high school. And Rachel and Kim refer to him as "queer".
* ExtremeDoormat: He lets Guy boss him around, belittle him and casually insult his girlfriend with feeble attempts to prevent it. Guy even manages to convince him to [[{{Squick}} drink his piss]] in one episode.
* HilariouslyAbusiveChildhood: He is hinted at having this. It's not surprising with a mother like [[spoiler: Joanna]].
* HeterosexualLifePartners: With Boyce.
* InnocentlyInsensitive: In his racist comments to Lyndon.
** He does unintentionally insult people, like pointing out in one episode Caroline's boobs look uneven in her top.
* LiteralMinded: When he whines to Karen that no woman has ever fancied him, she asks, "What about me?" and he replies, "What, has no woman ever fancied you either?"
* SensitiveGuyAndManlyMan: He's the Sensitive Guy to...Guy.
* StrongFamilyResemblance: [[spoiler: Guy and Martin, since they are half-brothers.]]
* VerbalTic: Stutters when particularly riled up.

'''Dr. Angela Hunter'''
* TheAce: Seems to be this in the first episode, but her more unsavoury personality quirks come into light as the show goes on.
* BitchInSheepsClothing: Often subtly undermining towards Caroline and likes being the centre of attention. Her bitchiness gets turned up to eleven after she becomes the face of a TV documentary set at the hospital.
** Interestingly, in a deleted scene with Sue White, Angela even lampshades it, saying she is ambitious, driven and will do ''anything'' to get ahead. The "niceness" is all a front. It's hard to tell if she meant it or if she was trying to big herself up to Sue, however.
* ControlFreak: She ''irons'' her pants.
* CovertPervert: Acts all perky and squeaky-clean, but also claims she gets off on "sticking [her] hand up women and delivering babies" and she finds jealousy, "Exhilerating! In-in a dirty sort of way..."
* HelloNurse: The director for the TV documentary becomes instantly smitten with her.
* HospitalHottie
* ICantDance: Angela's boyfriend comments, "She really is the perfect girlfriend...although...she does dance a bit like a wolf." Queue the camera panning to Angela doing just that.
* PerpetualSmiler
* PutOnABus: Dr. Angela Hunter gets what is probably the most generous bus-sendoff ever. That is, until she is later [[spoiler:killed off-screen in an unexplained incident with a moose, constituting a BusCrash.]]
* ParodySue
* TheThingThatWouldNotLeave: Irritates Caroline in hospital, then ends up becoming her flatmate.
* YouWouldntLikeMeWhenImAngry: Threatens Caroline with "don't make me get cross!" when she thinks [[ItMakesSenseInContext Caroline has stolen her pants.]]

'''Boyce'''
* BiTheWay: There are a few hints that he is.
* TheDeterminator: In a weird way, but he really goes above and beyond to annoy Alan.
* DuckSeasonRabbitSeason: Pulls this on Alan countless times.
* {{Dude Looks Like A Lady}}: He is referred to as a "porcelain ladyboy".
* TheGadfly: Mainly to Alan, but he sometimes playfully annoys Martin, Guy and Caroline, too.
* GayBravado: He does far too much of this in the company of Dr. Alan Statham, despite his sexual conquests with Kim.
* HeterosexualLifePartners: With Martin.
* HospitalHottie
* IcyBlueEyes: "Chipped-ice blue eyes", to be exact.
* LastNameBasis
* OnlyOneName
* ThePrankster
* ShipperOnDeck: He seems to support Mac and Caroline. It is he who tells Mac the truth about their relationship when Mac loses his memory.

'''Sue White'''
* AxCrazy
* {{Cloudcuckoolander}}
* ComedicSociopathy: Her hobbies including stalking people, molesting people, threatening to put SPELLS on people and shooting at people with a bow and arrow. She also gives birth to a lion cub, which raises a whole lot of questions that don't need to be answered.
* CrazyCatLady: She inexplicably has a few scenes in Season 1 riding a camel. She often barks like a dog and once says she will only answer Alan's questions, "In the language of a crow!"
* DeadpanSnarker: Like everyone else on this show, mostly towards Guy, Alan and Martin.
* GagBoobs: Constructs some out of newspapers once when she's bored, then throws one at Caroline.
* ImAHumanitarian: Non-violent example: she eats umbilical cord sushi.
* LargeHam: She actually wears a large ham costume as well in 2x01, though that's Mac's dream sequence.
* KickTheSonOfABitch: Frequently manages to one-up Joanna, which isn't something just anybody manages.
** She really doesn't like Holly. [[EnemyMine She even seems to put aside her hostility towards Caroline while Holly's around.]]
* MoodSwinger
* TheNicknamer
* SirSwearsALot: Swears frequently and pretty casually.
* StalkerWithACrush: She ''is'' this trope. The scene in which she makes a clay statue of Dr. Mac and considers differently sized genitalia is but one shining example. She even steals some of his genetic material [[ADateWithRosiePalms while he's comatose]] to try to impregnate herself with his child. All PlayedForLaughs, of course.
* {{Stalker With A Test Tube}}
* TheTease: To Guy.
* TomboyishPonytail: She calls it "The Squirrel".
* UnresolvedSexualTension: With Guy.
** She does sleep with him after the Slave Auction, but she makes him put on a blonde wig.
* ViolentGlaswegian: Not so much violent as outright mental, but still qualifies.
** She even lampshades it at one point when Mac suspects she's the one who sabotaged his other job offer by telling the hospital he was dead, "Oh, well, you've caught me there, I must be the only Scottish woman in creation, it must have been me, lock me up!"
* {{Yandere}}: For Mac, BIG TIME.
** Also, towards Caroline. When Holly is her main rival for Mac's affections, [[EnemyMine she cuddles Caroline at one point]].

'''Joanna Clore'''
* AbusiveParents: She is clearly the worst mother in the universe, [[spoiler: but it never stops Martin from declaring his undying love for her.]]
** [[spoiler: Her interactions with Guy after Season One are horrendously awkward, but she does at least ask (if incredibly grudgingly) after his wellbeing.]]
* AllWomenAreLustful: It says something that she was desperate enough to start a sexual relationship with Alan Statham, and there's her relentless pursuit of Lyndon and [[WhatDoYouMeanItsNotHeinous actually getting annoyed when builders don't wolf-whistle at her.]]
* BadBoss: She physically and verbally abuses not just her regular HR underlings, but also various doctors and surgeons around the building.
* BerserkButton: If you want an easy life, don't make references to her age.
* BlondesAreEvil
* BitchAlert: She's needlessly sarcastic, bitter and insulting to pretty much everyone (especially Alan), but she sometimes tries to put on a syrupy, pleasant fašade in front of Lyndon. [[GenreSavvy Naturally, she's not fooling anyone.]] Amusingly, Alan even subtly makes fun of her for this. (Albeit not to her face).
* ChristmasCake: She ''knows'' she's this, but refuses to admit it, to the extent where she won't let [[spoiler: Martin tell anybody he's her son]] in case they figure out how old she is.
* DeadpanSnarker
* ItsAllAboutMe: She shows very little concern for anyone aside from herself (and Lyndon).
* Jerkass
* KickTheDog: Constantly. The biggest example is probably rubbing Harriet's face in it when the latter becomes pregnant again, knowing full well Harriet doesn't want another child.
* NakedInMink: Tries to seduce Lyndon this way. It doesn't work.
* ReallyGetsAround
* OutlawCouple: With Alan in the special.
* PetTheDog: She does at least send Martin a post-card when she goes on the run, and it's implied it's because of her he's allowed to keep his job despite failing his exams.
* VillainousBreakdown: [[spoiler: After figuring out Guy is her son...just after they've had sex.]]

'''Karen Ball'''
* ACupAngst
* BitchInSheepsClothing: She spends the first series as a bullied, self-loathing, friendless ButtMonkey. By the time the Special rolls around, she is a flashy, arrogant, domineering bitch who eclipses Rachel in social status and positively terrifies the rest. Granted, the last appearance of her before the special, she got knocked out of a window and nobody even noticed.
* {{Buttmonkey}}
* TheChewToy
* ExtremeDoormat: The HR staff walk all over her (Joanna forgets her name half the time), Kim and Rachel give her stupid advice on how to win Martin (like telling her she "looks better crouched down", leading her to spend an entire day crawling around the office.) and she generally seems to be the only one who actually does any work.
* GranolaGirl: One episode has her coming in wearing vegan shoes. However, she is informed by Rachel and Kim that gecko is a kind of small lizard.
* PlainJane: Type C.

'''Harriet Schulenburg'''
* BadLiar: She goes into involuntary spasms of blinking and facial twitching whenever she lies.
* BewareTheNiceOnes: She can be pretty assertive when pushed too far.
* TheDitz: She manages to forget either her kids or an article of clothing in about every episode. She once arrived at work and a cat jumped out of her bag.
* ComicallyMissingThePoint: Often.
* CovertPervert: She seems sexually frustrated, as her husband "hasn't slept with her since Oscar was born" and almost cries when she gets a "twinge down there."
** She also asks Lyndon to call her "Giselle" when they have sex.
* SympatheticAdulterer: Given what we hear about her home life, Ian doesn't treat her very well and she has four very annoying children to deal with.
* [[TeamMom Team Mum]]: Sort of. She does help Caroline get a pen top out of her nose.
* YourCheatingHeart: It's implied her husband is cheating on her with Rosy "pin-legs, slitty-eyed" Kendall, but she also has an affair with Lyndon.

'''Kim Alabaster'''
* DeadpanSnarker
* EyeScream: Gets sperm in her eye in episode one.
* SeriousBusiness: Minestrone is ''not'' a flavour.
* ThoseTwoGuys: With Rachel.
* {{Troll}}: To Joanna, but she really does deserve it.
** Also to [[TheChewToy Karen.]]


'''"Naughty" Rachel'''
* BuxomIsBetter
* DeadpanSnarker: Mainly towards Karen and Martin.
* HelloNurse: Ollie seems to have a bit of a thing about her, and she's implied to have slept with Guy.
* OnlyOneName
* ReallyGetsAround: She takes pride in it.
* ThoseTwoGuys: With Kim.
* {{Troll}}: To [[BadBoss Joanna]] and Karen.

'''Lyndon'''
* BaldofAwesome
* BewareTheNiceOnes: Lyndon finally snaps after Joanna buys him in the Slave Auction and gives her a TheReasonYouSuckSpeech, calling her "tedious, disturbing and desperate".
* BlackAndNerdy: He's the IT guy, though he doesn't really seem like a stereotypical nerd.
* ChickMagnet: a handsome, sweet-natured IT consultant who is regularly called out to perform mundane, bullshit tasks by regular nurses and clerks who find themselves besotted with him.
* DeadpanSnarker: Usually toward either Guy or Alan, both of whom are jealous of his effortless ability to attract women.
* EvenTheGuysWantHim
* HeteroSexualLifePartners: Implied this is the direction his friendship with Jake might go.
* HospitalHottie
* OnlySaneMan: Even to Mac.
* OppositesAttract: He could get any woman in the hospital he wanted, but he likes Harriet.
* TheScapegoat: He has zero interest in Joanna and merely tries to politely rebuff her advances, but it doesn't stop Alan from threatening/harassing/stalking him to try and keep him away from her.
* TokenMinority

'''Holly'''
* BabyTrap
* BlondesAreEvil
* BitchInSheepsClothing: She claims she wants to be friends with Caroline and is very touchy-feely with her, but immediately calls her "that weirdo Todd" when Mac pretends to choose her over Caroline.
* TheGhost: In Season One.
* ImplausibleDeniability: Ironically a trait she shares with Caroline. But she keeps trying to maintain that [[spoiler: Mackenzie is Mac's son]], even when he produces not only orange hair-dye (she claims it's for a friend who is [[BlatantLies "phobic, for some reason, about buying hair-dye"]]), but also [[spoiler: a DNA test.]]
* ManipulativeBitch
* NoSenseOfPersonalSpace: Which makes Caroline very uncomfortable.
* RomanticFalseLead: She happens to appear just as Mac and Caroline are about to lock lips. And when that isn't enough to put the brakes on, she pulls a small child out of her sleeve. Caroline often fantasizes about shooting her.
* TooDumbToLive: Kinda, but leaving orange hair-dye in her locker wasn't a particularly smart move with Sue White around.

'''Jake Leaf'''
* DeadpanSnarker
* HeterosexualLifePartners: His last scene implies he and Lyndon will develop into this.
* LongHairIsFeminine: It's only about shoulder-length, but it doesn't stop Joanna referring to him as "Alice."
* TheShrink
* SuddenlyShouting
* RomanticFalseLead: Works well as this because he's likable enough in his own right, it's just that Caroline and Mac have a strong connection despite Holly's interference. He comes off a bit like a ThirdOptionLoveInterest for Caroline (compared to Guy and Mac), but things don't work out.
* TranquilFury: He does a very good job of keeping calm when Caroline accidentally drops his twelve-year-old Tamagochi into a wine glass on a date.
* WhatTheHellHero: Passive-aggressively calls out Caroline for dating him when it's obvious she's still in love with Mac, but they do mainly part on amicable terms.

'''Emily "Emmy" Louise Westbrooke'''

* DumbBlonde
* NamesTheSame: To another Emily Louise Westbrooke, who is merely pretending to be a physiotherapist and is actually a con artist. Caroline is rather dismayed to learn she's got the wrong Emily Louise Westbrooke.
* ParodySue
* RomanticFalseLead: Briefly dates Mac in Season One, just to make things more frustrating for Caroline, but she clearly doesn't really "get" Mac's sense of humour.