!!Kaitlin "Katie" Greenbriar

The protagonist of Gone Home, Kaitlin is a 21-year-old college student who returns to her family home after a year abroad in the middle of a stormy night to find the house empty, apparently ransacked, and filled with mysterious notes from her younger sister. The game details Katie's investigation of the house and what happened to her family in the year she's been gone.

* CoolBigSis: How Sam sees her
* DecoyProtagonist: The story begins with the impression it's about her returning home, immediately it becomes clear she's not the real star.
* TheGenericGirl: While we get a few glimpses of her personality through postcards and such, she's basically a cipher.
* OnlySaneWoman: Seems to be the only member of her family who isn't screwed up in one way or another.
* PluckyGirl: The impression one gets of her from her phone call to her parents and the various postcards found around the house. We don't get to know Katie as well as Sam, but from what we can tell she's adventurous and responsible, but with a slight goofy streak.

!!Samantha "Sam" Greenbriar

Katie's 17-year-old sister. Unlike the apparently more popular and conventional Katie, Sam's always been a bit of a loner and an outcast. Much of the story revolves around Sam's struggles in the year Katie was away, as revealed in the many journal entries Katie finds throughout the house.

* CharacterDevelopment: [[spoiler:Her relationship with Lonnie inspires her to increasingly come of her shell and take more risks, culminating in her running off with Lonnie.]]
* NonPOVProtagonist: While the player plays as Katie, the story itself is really about Sam's life over the last year.
* TheSnarkKnight: Perhaps the best example being the health class assignment of hers you can find, which reads like a spot on pastiche of the glimpses we get of things [[WesternAnimation/{{Daria}} the former trope namer]] wrote in the show (cf. the ''Melody Powers'' stories).
* StraightGay: [[spoiler:Characterized as being bookish and socially withdrawn, Sam doesn't fit traditional lesbian stereotypes as much as the tough, army-focused Lonnie.]]
* TheUnfavorite: One of the very first things you see in exploring the house is Kaitlin's prominently displayed trophies in the foyer, on the flip side Sam seems to be frequently marginalized and her interests/feelings ignored. One possible reason for this is that she takes after her father more, and he doesn't like himself much.

!!Terrence "Terry" Greenbriar

Katie and Sam's father, a failed author who now writes mindless reviews of hi-fi equipment for a magazine.

* {{Adorkable}}: Lonnie notices how he was rather awkward during the Thanksgiving Dinner she visited Sam for, and she actually found it rather funny and endearing.
* TheAlcoholic: Irish Whiskey and Vodka being his preferred methods of self-medication.
* EarnYourHappyEnding: [[spoiler:After struggling with his novels selling poorly for years, frequently driving him to the brink of depression and entirely giving up on writing, his move to a new publisher leads to a breakthrough in sales, and the newfound demand even inspires him to write a sequel.]]
* ParentalObliviousness: Like Jan, he is clueless for a long time about [[spoiler:Sam's sexuality and the fact that she is in love with Lonnie]]. Though judging from their reaction when they do find out, it is hinted that an element of SelectiveObliviousness is also in play.
* WellDoneSonGuy: [[spoiler: A lot of his issues seem to stem from his author father's decided lack of approval or respect for his son as a writer. Interestingly, this seems to carry on to his relationship with Sam with whom he shares a distant relationship despite having a great deal in common with her.]]

!!Janice "Jan" Greenbriar

Katie and Sam's mother, an ecologist struggling with an unhappy marriage and a daughter she doesn't understand.

* LoveMakesYouDumb: [[spoiler:Gets seduced by an attractive male subordinate into recommending him for a promotion only to find out he was doing it so he could afford to marry his girlfriend and start a family.]]
* ParentalObliviousness: Like Terry, she is clueless for a long time about [[spoiler:Sam's sexuality and the fact that she is in love with Lonnie]]. Though judging from their reaction when they do find out, it is hinted that an element of SelectiveObliviousness is also in play.
* YourCheatingHeart: Most of her plot revolves around her attraction to a park ranger on loan to her station.

!!Richard Greenbriar

Terry's father, an English teacher, philosopher and published author.

* InsufferableGenius: Richard is a pompous dick with a high opinion of himself and a low opinion of his son.
* JerkWithAHeartOfGold: It's ultimately shown that Richard ''does'' want the best for his son -- he's just not very good at expressing it.
* SciFiGhetto: In-universe, what he thinks of Terry's time-travel novels.

!!Yolanda "Lonnie" [=DeSoto=]

A girl at Sam's new school, Lonnie is a social misfit and punk and Sam finds herself captivated by her.

* ButchLesbian: A member of the Junior Reserve Officers' Training Corps, an organization for youths who wish to train to join the army before they are of legal age.
* MilitaryBrat: Her father was apparently a soldier and she desires to follow in his footsteps.
* RiotGrrrl: Introduces Sam (and a goodly portion of the audience) to the joys of Bratmobile.
* RuleAbidingRebel: As pointed out InUniverse by Sam through one of her journal entries, her career choice clashes pretty badly with everything else about her.
* WrenchWench: Works on motorcycles with her dad and her desired MOS is tank mechanic.

!!Oscar Masan

Terry's recently-deceased uncle who willed him the mansion in which the Greenbriar family newly resides. His mysterious reputation in Boon County has caused the mansion to be labeled "The Psycho House"

* TheAtoner: It's implied that leaving his sprawling house to Terry after his death is a belated attempt to atone for his [[spoiler:sexual abuse of Terry when he was twelve years old]].
* BigBad: Most of the bad stuff that happens in the game can be laid directly at his feet, though it takes some digging to figure out exactly why.
* CoolUncle: Subverted InUniverse. As Terry's father, Richard, was a rather cold and demanding parent, he found it much easier to bond with Oscar and was evidently very fond of him, paying him frequent visits through his childhood, until [[spoiler: Oscar made "[[CreepyUncle the transgression]]" on him]].
* CreepyUncle: Everyone in ''town'' thought he was creepy. Along with all the secret passageways in his home, the alleged ghost sightings in the house, and the dark implications of his actions, he seems downright sinister. And that's not even mentioning [[spoiler:what he did to Terry when he was twelve years old]].
* MaybeMagicMaybeMundane: Sam and Lonnie believe his ghost is haunting the house and claim to have seen some weird stuff going on, but it's just as likely that the house's screwy electrical systems are to blame.
* TheHermit: Closed his business in 1965, and there's no evidence he even left his house between 1972 and 1993 (when he died).