[[folder:Pearl Jones]]
!Pearl Jones
A young girl living in LA during the 1920s with dreams of stardom... until she's invited to the wrong party.
* ActionGirl: After being converted into a vampire.
* BattleCouple: With Henry.
* BreakTheCutie: Pearl was just a rising starlet until she ran into a party hosted by vampires who nearly drained her dry. And to make matters worse, the person who arranged for her death was her ''own best friend''.
* EeriePaleSkinnedBrunette: Not as pale as the European vampires since she can walk in the sunlight so she got a nice tan, but whenever she enters in [[GameFace vampire mode]], her skin becomes extra pasty.
* FriendToAllChildren: In ''Second Cycle'', she turned her family household into a safe haven for vampire children.
* FromNobodyToNightmare: While she is [[BewareTheNiceOnes a nice and sweet woman]], she certainly qualifies for this trope from the Euro-Vamps' perspective: like many girls before her, she was given as "prey" for the Hollywood Coven to feed on, and after they were done they dumped her body into a ditch to be forgotten. However, she survived long enough to be found by Skinner Sweet, who gave her an EmergencyTransformation and turned her into another American Vampire and proceeded to hunt down those responsible.
* TheHeroine: She is the closest thing the comic has to one, in stark contrast to [[VillainProtagonist Skinner Sweet]].
* HunterOfHerOwnKind: Pearl occasionally works with [[VampireHunter the Vassals of the Morning Star]] to fight other vampires, specially American ones just like her.
* OurVampiresAreDifferent: The american vampire has elongated finger-claws, rattlesnake fangs, and are powered by sunlight, only becoming vulnerable during the nights of the new moon and can only be killed by gold.
* MamaBear: To the vampire children in her care in ''Second Cycle''.
* NiceGirl: Even after being turned into a vampire, she tries to live morally.
* RoaringRampageOfRevenge: Against the Hollywood Coven for nearly killing her.
* TookALevelInBadass: After becoming a vampire.
* UnstoppableRage: Pearl. After the Hollywood Coven does bad things to her, her rage is only stopped when they're corpses.
* ViolentlyProtectiveGirlfriend: While Henry's usually able to handle himself, if he's in over his head, particularly against vampires, Pearl's right there and ready to rumble.

[[folder:Skinner Sweet]]
!Skinner Sweet

A psychotic outlaw in the Wild West who runs afoul of the Pinkerton Detective Agency and a group of European vampires. Becomes the first American Vampire.
* ArchEnemy: Sweet has the tendency to become this for a lot of people: Jim Book, Abilena and her daughter Felicia, Travis Kidd, Cash [=McGogan=], the entire Carpathian coven, etc...
* AxCrazy: Whenever he shows up, there's a very good chance a lot of people are going to end up dead.
* BackFromTheDead: [[spoiler:As of #23.]]
* BuriedAlive: For 20 years.
* BroughtDownToNormal: [[spoiler: Skinner is cured of his vampirism at the end of ''Second Cycle'' and to his distress he learns that he can't be infected again.]]
* CharacterTics: He likes to chew or suck on candy. Readers can always identify Sweet whenever he is disguised or taking another identity by his yellow eyes and him always chewing on candy.
* ChronicBackstabbingDisorder: If you ally with him... watch your back.
-->'''Skinner Sweet''': ''"Everyone who meets me knows I am just plain pitiful at keeping deals... And I always got to be the last man standing."''
* EvilFormerFriend: Formerly Jim Book's best friend and adopted brother.
* FauxAffablyEvil: Sure he seems like a friendly guy, but don't let that fool you. He'll rip you to shreds without a moment's hesitation, just for a laugh.
* FirstOfItsKind: The first American Vampire.
* FromNobodyToNightmare: From an orphan adopted by Jim Book's family to a notorious outlaw that by pure chance becomes the first American vampire, even stronger and more dangerous than the common bloodline.
* JokerImmunity: Has a knack for evading death several times.
* ManipulativeBastard
* OurVampiresAreDifferent: The american vampire has elongated finger-claws, rattlesnake fangs, and are powered by sunlight, only becoming vulnerable during the nights of the new moon and can only be killed by gold.
* PetTheDog: Skinner saving Pearl's life may count (though it is possible he has ulterior motives or simply wanted to screw up the Hollywood Coven's plans).
** In ''Second Cycle'', [[spoiler: he attempts to pull off a HeroicSacrifice to save Calvin's life when Sweet is about to be possessed by the Beast influence]].
** Skinner's interaction with Kitty at the ending of 'Strange Frontiers'.
* RedemptionEarnsLife: A literal and surprisingly dark variant for this trope. [[spoiler:After a lifetime of crimes, betrayals and atrocities, he decides to sacrifice his live to save Calvin by manually directing their spacepod from outside to enter Earth's atmosphere, while burning during re-entry. He wants to do this because the Beast is currently inside his body and he wants to take it out while still being himself... He manages to survive the process and find out he has been cured of his vampirism, making him technically alive again.]]
* SlasherSmile: Seems to be his preferred expression.
* SweetTooth: He retains this trait even after becoming a vampire.
* ReforgedIntoAMinion: [[spoiler:A heroic example: he is found and resurrected by the Vassals of the Morning Star just to serve as their agent.]]
* VillainProtagonist: While Pearl is TheHeroine, Skinner carries the plot a great more deal.
* TheWildWest
* WorthyOpponent: Skinner sees Jim Book as this, as seen in 'Strange Frontiers' when he murders the actor who is playing the part of Book in a Wild West show.
-->'''Skinner:''' You don't deserve to wear Jim Book's name! *tears off head*

[[folder:Henry Preston]]
!Henry Preston
A Marine who served in World War I before becoming a traveling musician who crosses paths with Pearl in Los Angeles and falls in love with her.
* BadassNormal: Otherwise, a normal human next to his wife, who is an American vampire.
* BattleCouple: With Pearl.

[[folder:Hattie Hargrove]]
!Hattie Hargrove
Pearl's best friend and roommate, also an aspiring actress.
* AxCrazy: [[spoiler:When she comes back from her near-death experience, she becomes much more wantonly murderous and bloodthirsty.]]
* EvilFormerFriend: Goes from Pearl's best friends to one of her greatest enemies.
* EvilIsPetty: Set her best friend up to be vampire-chow just so she can become a famous actress.
* EvilRedhead: An AxCrazy vampire with bright orange hair.
* GlasgowGrin: As the result of having the gold star from her dressing room shoved down her throat.
* IHaveYourWife: Pearl is lured into an ambush when Hattie gets kidnapped by vampires. Unfortunately for Pearl, Hattie is in on the whole thing.
* NotQuiteDead: [[spoiler:Pearl appears to kill her near the end of volume one, only for it to eventually be revealed that she was merely put into a death-like state. Other vampires recovered her body from the morgue and used her as a guinea pig to find out the weakness of American Vampires.]]

[[folder:James Book]]
!James Book
A veteran of the Civil War, he becomes a detective in the Pinkerton Detective Agency and hunts down Skinner Sweet.
* HeroicWillpower: Jim manage to go on without feeding for ''three years''. Sure, he was tormented the whole time, but that is damn impressive.
* ICannotSelfTerminate: [[spoiler:Asks his best friend's daughter to kill him rather than live as a vampire.]]
* MayDecemberRomance: His best friend's daughter has a crush on him despite possibly having at least 20 to 40 years on her. [[spoiler: Taken to an extreme degree when she only agrees to kill him if he slept with her and gave her a child to remember him by.]]
* PinkertonDetective: A rare example of one played purely heroically.
* TragicMonster: [[spoiler:Gets turned into an American Vampire when Skinner Sweet's blood enters his body.]]

[[folder:Abilena Carmino]]
!Abilena Carmino
The daughter of Jim Book's partner Felix Carmino.
* ActionGirl: She was willing to jump into the fray along with the men when Skinner re-emerged.
* ActionMom: Abilena joined the Vassals of the Morning Star following Felicia's birth and became a top agent.
* MayDecemberRomance: Abilena always loved Jim, who was old enough to be her father.
* NeverMessWithGranny: She served the order way past the 60s before resigning.
* StakingTheLovedOne: Not really staking, but she did gun Jim Book down during the New Moon at his own request to end his suffering.
* TeethClenchedTeamwork: [[spoiler:She was forced to fight alongside Skinner Sweet, the man who ruined the love of her life.]]
* VampireHunter: As a member of the Vassals of the Morning Star.

[[folder:Felicia Book]]
!Felicia Book
Jim Book's daughter (born after [[spoiler:his death]]). Is seeking vengeance on Skinner Sweet and becomes an agent of the Vassals of the Morning Star.
* ActionGirl: She is a top member of the Vassals of the Morning Star and proficient vampire hunter.
* ActionMom: [[spoiler:Ends up raising Gus [=McGogan=] as her own son]].
* BigGood: Following [[spoiler:Linden Hobbes' sacrifice]], she leads the Vassals and takes the order into a new direction: to fight against evil, instead of merely hunting vampires.
* TheChosenOne: One of the Ancients Vampires that were awakened in ''Survival of the Fittest'' refer to one as one, but to what purpose its not said.
* {{Dhampyr}}: Her father was an American vampire and her mother was a human. While she doesn't necessarily show any obvious vampiric traits, she is not completely human either. In ''Second Cycle'', she has shown no obvious signs of aging despite her being over 50 years old.
* EvenTheGirlsWantHer: In ''Survival of the Fittest'' a group of female VMS agents {{Squee}} as she passes by.
* ItsPersonal: Skinner turned her father Jim into a vampire, who was so tormented by his state he begged Abilena to kill him after [[SomeoneToRememberHimBy providing her with a child]].
* MsFanservice: While Felicia doesn't usually play this role and dresses modestly, she had a completely gratuitous nude scene in ''Survival of the Fittest'', being the only female character to feature one in the comic so far. Pearl was nude in her introduction, but the circumstances were [[FanDisservice disturbing rather than titillating]].
* NoSell: One Carpathian vampire tried to bite her, only to recoil away in disgust from drinking her blood.
* PromotedToParent: [[spoiler: She pretty much raises Gus following his father's passing]].
* SomeoneToRememberHimBy: Felicia was conceived by her parents as part of an agreement that her mother would end her father's suffering if he gave her a child.
* VampireHunter: The HunterOfHisOwnKind variant of {{Dhampyr}}, and a member of the Vassals of the Morning Star.

[[folder:Cash McCogan]]
!Cash [=McCogan=]
The police chief of Las Vegas in 1935 who is drawn into a string of mysterious deaths that bring him into the world of vampires.
* ActionDad: He joins the Vassals of the Morning Star after his son's birth.
* DyingMomentOfAwesome: [[spoiler:Cash goes out in a true blaze as he makes his last stand against the Nazi vampires, singing "The Star-Spangled Banner" and then detonating several grenades]].
* FindTheCure: His goal in ''Survival of the Fittest'' is to find the cure of vampirism to his son. [[spoiler:He does at the cost of his own life]].
* HappilyAdopted: His father was a sheriff who adopted him when no other couple would.
* HeroicSacrifice: [[spoiler:In order to ensure Felicia's escape and takes the cure to his son, he performs a final stand against the pursuing vampires detonating several grenades strapped to his body.]]
* MoralityPet: To his father Gus, who was a Gaelic-Prime vampire.
* TraumaCongaLine: Cash's investigation leads him to lose his adoptive father and his wife, both of them victims to Skinner Sweet, and his unborn son being turned into a vampire by Skinner's blood injection.
* VampireHunter: A member of the Vassals of the Morning Star.

[[folder:Linden Hobbes]]
!Linden Hobbes
A mysterious agent who is the leader of the Vassals of the Morning Star.
* BigGood: He leads the Vassals of the Morning Star at the time of the series.
* CoolOldGuy
* DyingMomentOfAwesome: [[spoiler:Dies in a MutualKill with Dracula.]]
* KnightTemplar: Surprisingly averted. In his first appearance, he seems to be obsessed with destroying all vampires, no matter how harmless, however, by the 'Lord of Nightmares' arc, he's mellowed out a lot, allying himself with Pearl and Felicia, two known vampires, as well as allowing The Firsts, a group of surviving vampires who are out to kill Dracula to live.
* ReasonableAuthorityFigure
* VampireHunter: The leader of the Vassals of the Morning Star.

[[folder:Calvin Poole]]
!Calvin Poole
An African-American VMS agent, he is part of Henry Preston's team in ''Ghost War''. He becomes an American Vampire at the end of that arc.
* BewareTheNiceOnes: He is harassed by a couple of racists and he even gives them one last chance to apologize. Had they known they were MuggingTheMonster.
* BlackDudeDiesFirst: Inverted; he is the only African-American member of the team and survives the ''Ghost War'' ordeal, but emerged as an American Vampire.
* NiceGuy: Very mild-mannered and comforting to his friends.

[[folder:Travis Kidd]]
!Travis Kidd
A young, rebellious vampire hunter in the 1950s who is... extremely talented at killing vampires.
* BadassNormal: Possibly the series's greatest example, lacking any powers, allies or decades of expierence, but still taking on scores of vampires on his own and fighting Skinner Sweet to a standstill.
* GreaserDelinquents
* VampireHunter: He's very good at what he does, despite being a BadassNormal.

[[folder:Gus McGogan]]
!Gus [=McGogan=]
The son of Cash and [=Lilly McCogan=] who due to tragic circumstances was born a vampire thanks to the notorious Skinner Sweet.
* TheChosenOne: [[spoiler: By {{Dracula}} to become his vessel.]]
* CreepyChild: When we first see the poor kid, he is a small and disfigured vampire baby trapped inside a cage and being fed small animals by his father.
* DeadGuyJunior: Gus was named after his grandfather, who was a ancient Celtic vampire.
* GenerationXerox: His story tragically mirrors his father's as both of them were [[spoiler:orphaned at early age and adopted by someone else]]. He is also a vampire like his grandfather and namesake, although Gus the Elder was a Gaelic-Prime, while little Gus is an American Vampire.
* FetusTerrible: He was born twisted and disfigured as result of Skinner injecting Lilly with his blood while she was pregnant with Gus.
* TragicMonster: Poor kid was just another victim to Skinner.

The first Carpathian vampire, the originator of the European strain.
* ANaziByAnyOtherName: While the comparisons are not flat out stated, Dracula and by proxy, his progeny, shares some subtle characteristics with them such as racial supremacism and carrying out a genocide against other vampire bloodlines for considering them "inferior" like the humans. While Dracula himself was locked up in a prison by the time of World War II and did not see the Nazis himself, his followers sided with them due to sharing their same MasterRace beliefs and going as far as experimenting on other vampires.
* TheDreaded: He is always referred to in a ominous manner and with good reason. The prospect of him being released into the world terrifies Hobbes.
* {{Dracula}}: Its stated that the fictional character were inspired by him.
* FromNobodyToNightmare: Its speculated that rather than [[UsefulNotes/VladTheImpaler a nobleman]], he is also believed to have been a mere pig farmer before rising up as vampire. At the time he was created, his bloodline wasn't particularly powerful or virulent and went by largely ignored by the Vassals until the 1700s, when they became the most populous vampire species in Europe and nearly wiped out the every other species in the world in the following century.
* HumanoidAbomination: Rather frighteningly, he is depicted as a being made of shadows than anything close to a human.
* MindRape: He is capable of causing this: when Albert, Duke of Clarence requested to see Dracula in person, he was driven insane.
* MonsterProgenitor: To the Carpathian bloodline.
* MultipleChoicePast: Naturally, UsefulNotes/VladTheImpaler is among his many identities speculated by the Vassals of the Morning Star.
* NoNameGiven: "Dracula" is not really his actual name, merely how he is referred by characters because how he inspired the book.
* SealedEvilInACan: At some point while attempting to reach America by sea, he was captured by the Vassals and trapped inside a vault
* TheSpook: Besides him being of Romanian origin, his true identity and how he became a vampire in the first place are unknown.
* StrongerWithAge: One thing that makes him so much dangerous than Skinner is that Dracula is so much stronger and powerful than any of his progeny.
* UltimateEvil: His body is almost always covered in shadow.
* VampireMonarch: The European vampires started with him and its stated he has absolute control over all of them.
* VillainOfAnotherStory: While he is part of the setting's background and his influence affects them, he is never faced by the protagonists in the main series. Rather, he is the BigBad in the limited minisseries ''Lord of Nightmares''.

[[folder:The Gray Trader]]
!The Gray Trader
A mysterious and enigmatic figure who is one of the most feared and dangerous threats to the Vassals of the Morning Star.
* ColdBloodedTorture: He is shown interrogating a native by ''dismembering very slowly''.
* TheDragon: Originally thought to be a strong contender for BigBad in the series, he is actually serving the will of the Beast.
* TheDreaded: Anyone who knows him sweats and trembles in fear from just hearing his name.
* TheFaceless: His face is always covered in darkness, his eyes being little white dots.
* FallenHero: He was not just a VMS member, but the order's actual founder.
* HumanoidAbomination: One even more horrifying than ''Dracula''.
* IHaveManyNames: Hurin, the Great Protector, the Great Traitor, the Grey Trader, the latter is a bastardization of his Great Traitor from over the years.
* TheParagonAlwaysRebels: Originally, the Vassals of the Morning Star were united under his banner to fight the Beast. They ultimately succeeded in defeating it, but their leader suckled on the monster's teats, gaining its power and becoming his champion. His actual name is supposed to be the Great Traitor, but it has been bastardized to its current form.
* SatanicArchetype: Calvin calls him the actual Devil. He is actually not quite, but as Felicia explains his backstory he fits the archetype regardless, see TheParagonAlwaysRebels.
* SharpDressedMan: He wears an old gentleman's costume.
* WasOnceAMan: A normal human at first, but then he became the Beast's champion, he was elevated into... [[HumanoidAbomination something else entirely]].

[[folder:The Beast]]
!The Beast
An ancient entity that plagued the Mesopotamic world with its demonic offspring, the Vassals of the Morning Star were created to defeat her. They succeeded in doing so, but it was not destroyed, since it managed to successfully corrupt the order's founder Hurin into becoming its protector and champion.
* AncientEvil: It was released on Earth in 13.000 BC and for a thousand years reigned supreme until the Vassals challenged it.
* BigBad: Quite possibly the greatest example in the series, bigger than [[VillainProtagonist Skinner]] and [[VampireMonarch Dracula]].
* TheCorrupter: Its "[[TheCorruption milk]]" turned [[TheParagon Hurin]] into [[TheParagonAlwaysRebels the Great Traitor]]. Its also capable of turning other beings - and yes, including vampires - into its servants.
* EldritchAbomination: This thing used to walk the Earth when mankind was still young, terrorizing mortals with its demonic spawn. Its a force of nature beyond human and vampire comprehension.
* IHaveManyNames: Tiamat, the Mother of Beasts, the Dragon, the Worm.
* MotherOfAThousandYoung: It had spawned countless demons upon the world and can turn her human minions into monsters.
* OutsideContextProblem: While the Vassals were founded specifically to fight it and its minions, this thing is a whole new can of worms seemingly unrelated to vampires and belonging to a CosmicHorrorStory instead of this one. The heroes also are poorly equipped to take care of it.