* In ''Manga/DeathNote'', L decides to keep Light under supervision by handcuffing himself to Light. Although L still suspects Light of being Kira, they become friends over this time, mainly because a type of LaserGuidedAmnesia has erased Light's memories of being Kira. Once the memories return and the handcuffs are off, however, [[MagnificentBastard Light continues to act as L's friend while plotting his death]].
* There are no literal chains in ''DoubleArts''--just the simple awareness that if [[HealingHands Kiri]] lets go of her hand for more than a few seconds, [[IllGirl Ellie]] will go into a horrific seizure and die. Needless to say, they are, for all practical purposes, just as good as chained together.
** Although they were able to take advantage of it not being ''exactly'' the same in the first chapter to win a fight by switching hands to get an advantage.
* In the ''Manga/{{Gintama}}'' anime, Hijikata and Okita are chained together at the neck with exploding collars as a parody of the ''{{Saw}}'' franchise. They spend the next few days foiling each other's attempts at escape.
** Hijikata got handcuffed to ''Gintoki'' and had to request his help in taking down some bad guys. HilarityEnsues.
* In Seo Kouji's oneshot manga ''HalfAndHalf'', the male and female protagonists are both involved in an accident and die together. Then a rather generic Kami-Sama gives them a chance to live again, for 7 more days; the catch is that after the time limit, one of them must die again. They're forced to stay together until they decide, else they both die.
* In a side story of ''KamichamaKarin'', Karin and [[JerkWithAHeartOfGold Kazune's]] [[TransformationTrinket magic rings]] ends up stuck together, and by extension their hands. Instead of having to make excuses for cuffs, they have to avoid being seen with their hands stuck together or face the wrath of Kazune's {{Fangirl}}s. This leads to some [[HilarityEnsues rather funny]] moments where Kazune has to go to the bathroom and where they have to change for gym. The latter leads to a CrowningMomentOfFunny where their enemy walks in on them in a... [[NotWhatItLooksLike compromising position]].
* Has happened a couple of times in ''Franchise/LupinIII'', when Zenigata actually manages to cuff Lupin. And quickly learns that the downside to cuffing yourself to Lupin, is that you are now cuffed to Lupin. [[EscapeArtist And he isn't chained to anyone.]]
* A ''Manga/{{Naruto}}'' filler episode recounts an instance where the original Team Kakashi faced a gang of thieves lead by [[CaptainErsatz Ninja Spiderman]](the guy even webswings in one scene). Naruto and Sasuke wind up with their hands webbed together for the remainder of the flashback. During the HilarityEnsues scene of trying to seperate themselves, [[HoYay they accidentally kiss...]] again.
--> '''Sasuke''': "[[LampshadeHanging Why is it always you?]]"
* Happens accidentally to Usopp and Zoro in ''Manga/OnePiece''. It culminates in [[spoiler: [[GrievousHarmWithABody Zoro using Usopp as a sword.]]]]
* Done in the ''Anime/{{Pokemon}}'' anime, in which Ash's Pikachu and Team Rocket's Meowth are tied together for an episode.
** Also in the ''PokemonSpecial'' manga with Blue[[spoiler:'s Ditto]] and Sabrina during a battle. Hilariously, Sabrina was ''furious'' to find out [[spoiler:that they weren't even chained together at all.]]
* In the manga as well as an episode of ''PrincessResurrection''. Reiri and Riza, a vampire and a half-werewolf respectively, end up getting handcuffed together by Hime as she needs them for a rescue mission knowing full well they would object to it if they had to work together.
* Having two characters chained together actually happens fairly often in ''[[RanmaOneHalf Ranma ]]''. Somewhat subverted in that they very seldom get along and generally find some way of using the other as the weighted end of a chained weapon.
** Such as Ranma using P-chan as both a shield and blunt object in a Martial Arts Gymnastics match with Kodachi.
*** "Pig is a valid weapon."
* Happened to Tsukune and Ruby in ''RosarioToVampire'', with the twist that every time Tsukune used his powers, Ruby would get electrocuted. [[TooKinkyToTorture She didn't mind]].
* ''Anime/SailorMoon'': An attack by a Daimon handcuffs Sailor Moon and Sailor Uranus together for an episode. This serves as a plot device since they'd been at odds since they ran into each other and have avoided contact. Being stuck together helps each to understand how the other thinks.
* In the manga ''TrainPlusTrain'', average everynerd Reiichi Sakasuka ends up handcuffed to fugitive Arena Pendleton. The cuffs are indestructible, but time-released. They just had to wait ''99 hours'', which meant that Reiichi had to cancel all his plans and go on the run with her. This was just the beginning of the tension between them.
* In Manga/DetectiveConan, when Heiji Hattori and Kazuha Touyama were kids, they got handcuffed while playing with a pair that belonged to Heiji's policeman dad. They spent a whole a day like that, and when they were released Heiji kept an amulet made with a piece of said 'cuffs. [[spoiler: Which would later become a PocketProtector, and save Conan from being stabbed to death.]]
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