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[[folder: ''Axis Powers Hetalia'' ]]

* ''[[http://www.fanfiction.net/s/5855349/1/Global-Inflation Global Inflation]]'' has [[AxisPowersHetalia all the nations at a meeting]] starting massively gaining weight as a result of economic inflation.

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[[folder: ''Comic Strip/Calvin And Hobbes'' ]]

* PlayedForLaughs in ''Fanfic/CalvinAndHobbesTheSeries'', where Calvin uses the Transmogrifier Gun to ''fuse ComicBook/TheRiddler's hands and feet together.''

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[[folder: Cross Over ]]

* Happens on a disturbingly regular basis in ''FanFic/FalloutEquestriaProjectHorizons''. Limbs melt and fall off, leg bones melt into jelly (forcing the victim to walk with a set of metal braces), an eye gets crushed in its socket by a rapidly-growing tumor, another character mutates into a writhing mass of tentacles, eyes, and mouths, Blackjack is forced to relive the experience of a pony being [[FusionDance forcibly merged]] with [[MixAndMatchCritters a cockatrice]], and a character is hit in the face with a burst of DeadlyGas, melting his eyes and sealing his nose and mouth shut forcing TheMedic to [[InstantDramaJustAddTracheotomy cut his trachea open to allow him to breathe.]]
* In ''[[http://azeira.deviantart.com/art/A-Madman-s-Circus-Part-1-314368512 A Madman's Circus]]'' is a ''Manga/DeathNote'' FusionFic with [[Music/{{Vocaloid}} Vocoloid's Dark Woods Circus]] the "attractions" at [[LightNovel/AnotherNote Beyond Birthday's]] CircusOfFear are a boy with his face half-blown off forced to dress as a girl, a girl with her eyes gouged out, and a woman nailed to a pole, burned alive and fitted with some sort of torture device in her neck so she screams on command. All of them were at one point just children and visitors stolen by the circus.

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[[folder: ''Manga/Death Note'' ]]

* The SlashFic ''[[http://archiveofourown.org/works/210760/chapters/315442 Not An Angel]]'' has a slightly more realistic (or rather {{Squick}}y) take on [[FreakinessShame WingFic]] that goes into detail about the organic processes involved of growing new appendages out of one's back.

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[[folder: ''Manga/Detective Conan'' ]]

* In ''FanFic/{{Experiment}}'', Haibara implants a strange metal into Conan to get him permanently back to his old self. However, after Shinichi realises [[GoneHorriblyWrong he has wires on his back]]...

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[[folder: ''Manga/Elfen Lied'' ]]

* In ''Fanfic/RoboBando'' Hdoug is constantly burned and tortured by Robo Bando to the point his body is a unrecognizable decaying, dying lump of flesh.

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[[folder: ''Web Comic/Homestuck'' ]]

* The Kin in ''FanFic/{{Hivefled}}''verse are the ghosts of young trolls who died in the Grand Highblood's torture chamber. Of the two most prominently featured, Laneen had the flesh stripped off her arms and an extra pair of horns surgically installed to make her look more like the [[{{Yandere}} Condesce's]] Helmsman, then had her throat cut when she [[DrivenToSuicide clawed out her own tongue to render herself boring]]. Her partner Sennir has [[TwoFaced half the flesh stripped off his head and neck]] and a gaping gutwound (though he was lucky in that [[spoiler:[[{{Transsexual}} his dead self is appropriately male]]).]] Gamzee escaped alive, but now has a broken horn and a GlasgowGrin. Various other ghosts have appeared, including a [[{{Squick}} twelve-year-old]] with a broken neck, a boy with crushed legs, a girl with a severed arm which floats beside her shoulder stump and another girl whose arm is missing completely, and a boy who died from drinking dirty water in a manner the authors tried to be subtle about ([[spoiler:most of his guts exited his body in an insalubrious manner]]).

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[[folder: ''Disney/Lilo And Stitch'' ]]

* The experiments' fates after Dr. Hamsterveil captures them in ''FanFic/WrathOfTheDamned''.

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[[folder: ''Western Animation/My Little Pony Friendship Is Magic'' ]]

* Two examples from ''FanFic/AsTwilightFalls''. First we have Luna [[PainfulTransformation changing Spike into adult dragon]] to fight a Discord's minion called Calamity. Then, we have Calamity himself a skeleton covered with mass of various creatures' bodies sewn together while they're still (mostly) alive.
* TD's Ponification in ''[[Fanfic/TheNonBronyverse Don't Go In the Everfree Forest, TD]]''. The change is initiated by stepping in a puddle that acts like [[FanFic/TheConversionBureau Conversion Potion]] cut with HollywoodAcid. When he gets home, he notices his leg's itchy. to quote; "I looked down at my leg. The skin was peeling. Not like 'few-day-old sunburn'. More like 'You can see your muscles.'" As it turns out, as more of his flesh sloughs off, the more ponified he becomes. Twilight has a freak out when she sees him [[HalfHumanHybrid in-between,]] fingers and toes fusing into hooves, one eye massively bigger than the other, rotting skin dripping off new fur. At one point, convinced he's always been a pony, he peels what's left of his human scalp off.
* The "[[WesternAnimation/MyLittlePonyFriendshipIsMagic Human in Equestria]]" story ''[[http://www.fimfiction.net/story/23095/you-do-not-belong You Do (Not) Belong]]'' has its protagonist begin [[spoiler:growing a unicorn horn after a few days in Equestria. The scene where it begins ripping a hole through the skin of his forehead, which he is then forced to tear off, is ''Film/{{Poltergeist}}''-level disturbing, and it looks like it will only get worse from here]].

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[[folder: ''Franchise/Sonic The Hedgehog'' ]]

* ''FanFic/SonicXDarkChaos'' is filled to the brim with this. One character gets ''their face melted off'' in a ruptured fuel line. Another is graphically [[ImpaledWithExtremePrejudice impaled]] by thorn-covered vines. [[TheVirus The Shroud]] take it UpToEleven, considering they're pretty much the lovechild of [[{{Halo}} the Flood]] and [[Film/TheThing1982 The Thing]]. And then there's [[TheCorruption Dark Chaos Energy]] and its {{Squick}}y effects on the body.

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[[folder: ''Franchise/Star Wars'' ]]

* In the ''[[FanFic/StarWarsParanormalitiesTrilogy Star Wars: Paranormalities]]'' trilogy, this is a common side-effect of Forceless possession for the victims. Aside from gaining a dark appearance and developing glowing red, crystal ball-like eyes, they may also have other mutations depending on the species of the host and intent of the Forceless symbiote. Such mutations may include {{ExtraEyes}} [[{{EyesDoNotBelongThere}} (sometimes in places they shouldn't be)]], extra body parts, an extra layer of skin, or having their internal organs shifted around in a way that makes the host dependent on the Forceless for survival. Also, the host is consciously aware of the mutations, and they are usually painful.

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[[folder: ''Comic Book/The Transformers'' ]]

* ''FanFic/{{Eugenesis}}'' gives us a [[SarcasmMode lovely]] description of a Cybertronian "budding" (I.E. their equivalent of giving birth). It happens quite immediately, without the subject being aware they were able to do that, hurts more than anything the subject has ever experienced or imagined, and very quickly involves various parts of their "biology" radically altering themselves simply to ensure the process is successful. Then, once it's done, it happens to them five more times. What's worse is that this is happening to the normally unflappable Soundwave.

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[[folder: [[Mega Ten Shin Megami Tensei ]]

* The Cambions and Guardians of ''FanFic/GoddessRebornChronicle'' can have this happen to them, as angels are most commonly [[NightmareFuel Cthulhu-like monstrosities and demons are often no better]]. Even worse, [[HumanoidAbomination the human inside is utterly gone when some fail their transformation]], leaving [[TheHeartless only the angel or demon in charge]]. There is [[AndIMustScream a refusal to think about if the human mind is still inside the 'husks' or 'abominations' by a Guardian]].