!!UK version:
* Creator/StephenFry (yes, that one) has a very unique way of playing ''Number of Words'' (normally one of the harder games) [[http://www.youtube.com/watch?v=v6gC62iwo7A here.]] You even see him counting off on his fingers a few times.
-->'''Fry''': I'm going to count... to six.
** "Well, I'm sorry, but it gets." ({{Beat}}) "My goat to hear her talking."
* [[http://www.youtube.com/watch?v=hH2gaCZmEtA&t=1m48s A game of Expert]] (obviously from the show's early years) had "taxidermist" as the suggestion for what Ryan was an expert on. Greg is then faced with the task of interviewing an unresponsive Ryan, who spends the entire game ''[[BlackComedy completely motionless.]]'' He doesn't flinch. He doesn't blink. He never once cracked a smile until the buzzer sounded. Even on repeat viewings, it's a mesmerizing, awesome performance.
* See the Josie Lawrence "faux-Albanian" clip. That was Jim's very first time on the show, where he got the idea to follow the trend of taking potshots at [[ButtMonkey Josie]]. ''And he pulled it off.''
--> "Sheep come in lots of different sizes. Little, middle and big. [[BestialityIsDepraved I like stroking the big ones... Some of those sheep play really hard-to-get...]]"
* Caroline Quentin's Song Styles [[http://www.youtube.com/watch?v=qtLEEYp8gX0 duet with Josie]], from the incredible pipes she unleashed to Colin and Ryan's ''standing ovation''. To think the song was supposed to be about [[LyricalDissonance a beached whale.]]
** On the last season of the British version of the show, Colin makes an awesome crack at Clive in World's Worst.
---> [[http://www.youtube.com/watch?v=kBs3XkG5fS4&t=1m33s "I'm Clive Anderson and I used to have no neck. But with new Neck Insert...Look! (rotates neck to the left and right)]]"
* In one of his first British appearances, Ryan is chosen to be the host of Party Quirks. He immediately guesses every quirk mere seconds after the guest walks in the door, and never has to be the host ever again.

!!First US version:
* [[http://www.youtube.com/watch?v=sbrlAeKqz9U One episode]] had Oscar-winner Creator/WhoopiGoldberg as special guest. Colin went toe-to-toe with her on "Questions Only," and ''managed to buzz her out''.
* One of Colin's best must have been during the "Going Bald" hoedown, after both Drew Carey and Brad Sherwood had riffed on Colin's distinct lack of hair. The look on his face as he is about to deliver it just cements it:
--->'''Colin''': ''People always kid me 'cause I'm losing all my hair / I can't really help it that I'm follically impaired! / It really is quite horrible, but my life is not through / I still get '''way''' more sex than either Brad or Drew!''[[note]]Colin is married. Brad and Drew were not at the time.[[/note]]
* [[http://www.youtube.com/watch?v=qXT6foyWZCw This]] Newsflash game is widely considered the show's single funniest game and the most awesome and heartwarming for Mochrie, if only for the line:
--->'''Colin''': It all started with a badly-timed bald joke!
** Which ironically makes it the best timed bald joke ever. Also, you can calculate to the second where it dawns on him.
* [[http://www.youtube.com/watch?v=rjETPB_q_h0 "We're watching animal porn!"]] Colin says something stupid, realizes how stupid it was, and delivers a spectacular punchline to his own stupid statement... all in less than ''seven seconds''.
* And from that same episode, we have Wayne and Jeff performing a jaw-dropping operatic song about motorcycles. It has to be seen to be [[https://www.youtube.com/watch?v=w3GweJDW8tE believed]].
* Considering the unscripted nature of this show, a few Moments stem from the genuine unplanned accidents that take place. Special mention must be made here of Ryan Stiles, who accidentally shattered the neon light on Drew's desk ''with his head, [[http://www.youtube.com/watch?v=v6Qtlfd9ul4 and refused to break character until the scene had ended]]''. Less damaging but equally Awesome 'accidents' include:
** Colin turning around an impossible rhyme in ''Irish Drinking Song (Slept With An Ugly Woman)'', ending the song with an apparently random, but [[CrossesTheLineTwice horribly sexist and yet fitting line]]. [[http://www.youtube.com/watch?v=xglZ8UTq5Fg 'She looked like someone had beat her'...]]
** Wayne and Chip are tasked with making up a Police song, and somehow both men get the idea to mimic [[http://www.youtube.com/watch?v=uRqG4kO9lck early Sting's signature 'Eeee-yoooh!']] ''at the exact same moment''.
** At the end of one ''Newsflash'' game. involving footage of [[http://www.youtube.com/watch?v=_Qpr4fpvAUQ numerous rats]], Drew admits that he didn't get Ryan's reference to the early MichaelJackson song 'Ben', upon which Ryan and Colin start singing one line of the song. Again, at the exact same time. Crosses into CrowningMomentOfHeartwarming in a way.
** In one ''Film Dub'' game, Wayne makes the assumption that one person in the film is about to get violent. [[http://www.youtube.com/watch?v=xiJNNM76cuU It pays off.]]
*** Even better, this follows a line from Ryan suggesting that the characters' outfits make them look gay. Right after he says it the other characters take off their suit jackets.
** In this [[http://www.youtube.com/watch?v=eAgqgfKgGpI classic "Song Styles" segment]], Wayne sang to Samantha, an aerobics instructor, in the style of Riverdance (Irish step-dancing). Wayne was suitably impressed to find out that Samantha actually could step-dance [[KneelBeforeFrodo he gave her a standing ovation afterwards]].
* A not-as-accidental one: Ryan, Wayne and Chip find out during one ''Hollywood Director'' game that the ''Stomp'' style of musicals actually fit perfectly into the show's improvised format. [[http://www.youtube.com/watch?v=KfCk3oxiN6M&t=3m25s The fact that the whole audience is clapping along by the end says it all.]]
** In a similar vein, this ''[[http://www.youtube.com/watch?v=J5-MNw1jzgo Sound Effects]]'' involves Colin as a monk who sneaks out of a monastery for a night on the town, so Ryan sort-of-beatboxes a club theme with Gregorian chanting thrown in. It works.
** And of course the infamous [[http://www.youtube.com/watch?v=8rcytPxviJk Y.M.C.A parody]] where Wayne and the others sing to a crowd member named "Howard". The tempo on the keyboard malfuctions, and the song suddenly speeds up, with the whole troupe trying to keep up.
*** And in the same game, Wayne manages to misspell Howard ("H-O-R-W-A-R-D!"). Throw in Howard's profession (designing closures for hazardous waste sites), Howard's enthusiasm and lack of rhythm, and the [[NiceHat silly hats]], and you have a perfect storm of hilarity.
* The ''Newsflash'' game is known for its use of increasingly obscure footage that most people wouldn't even believe existed - yet Colin has not only guessed very closely each time, but in one case, gave [[Film/TheValleyOfGwangi the movie's exact name.]]
--> [[http://www.youtube.com/watch?v=3CjZ_YE73oI "Oh, it's so horrible!... right here, in the Valley!... of... the Gwangi!"]]
* Chip's killer Snagglepuss impression during a [[http://www.youtube.com/watch?v=cHCSGRuxXtU Weird Newscasters]], finishing by running off and leaving his stool rocking just like in a Hanna Barbera cartoon. It's pretty much impossible to tell if that was deliberate. The only way it could have been better is if he actually got Colin to crack up afterwards; as it is he still needs a few seconds to regain his composure, something he's usually doing to everyone else.
* Awesome for Wayne and for the show's musicians - watch the back and forth between Wayne (singing in the style of Louis Armstrong) and the trumpet player [[http://www.youtube.com/watch?v=qYExbSA1EjY here]].
* One round of ''Weird Newscasters'' had Chip, as a gameshow announcer, inadvertently sabotaging Colin's ThemeNaming shtick by calling out his actual name. ''[[http://www.youtube.com/watch?v=sfwfXXCV9XE It doesn't stop him]]''.
--> "Iiiiiiintroducing COOOOLIIIIINN!!!!"
--> ({{Beat}}) "...Welcome to the 6 o'clock news, I'm Colin Themarines."
* After the director stops a sketch from being about Hitler, all the performers run with it for the rest of the show, [[GodwinsLaw sneaking references to Hitler into almost every sketch]]. Drew gets into the act by keeping a list of [[AcceptableTargets all the things it's apparently more okay to make fun of than Hitler]].
** Apparently the list includes Native Americans and bouncing boobs.
*** Video [[http://www.youtube.com/watch?v=FJfeTAm65NE here]] - the "up yours" to the director at the end is great.
* The crowner for Colin could have been that one game of ''Greatest Hits'' where he joined in on all of the dancing.
** Seen [[http://www.youtube.com/watch?v=dotjkFEaVd0 here.]] Impressively, he keeps up with ''[[TheCastShowOff Wayne.]]''
* Ryan said that his best time on the show was when he gave a passionate kiss to [[TheBradyBunch Florence Henderson.]]
* Creator/SidCaesar's [[http://www.youtube.com/watch?v=_dlr8fj4Y00 guest appearance.]] It's great to pay tribute to a comedy legend, but when he came on stage, he looked a little worse for wear. Then he breaks out into the greatest round of Dubbing the show has ever seen.
* Brad finds words that rhyme with the name [[http://www.youtube.com/watch?v=S4LU_2jHHc0 Naroshi.]]
** Even funnier when Drew jokingly dares Brad "try rhyming that!" As you can see, ''he does.''
* Wayne working the word ''[[http://www.youtube.com/watch?v=AJEiDukXtEc pachyderm]]'' into a song.
* One game of Greatest Hits featured Wayne and Josie having to sing in the style of GILBERT AND SULLIVAN. But really, all of the songs are just [[http://www.youtube.com/watch?v=0b6ZUwFvDVo awesome.]]
** And of course, who can forget this incredible rendition of [[http://www.youtube.com/watch?v=2otQnXXeI0Q#t=0m32s The Harley of Seville.]]
* Colin Mochrie is Captain Hair!
* Wayne's absurdly high note at the end of [[http://www.youtube.com/watch?v=9ybCvgxMlrk this]] game of Greatest Hits.
* Once when Wayne, Ryan, and Chip were playing Motown Group: Wayne and Chip turned in their usual brilliant musical performances; Ryan, who's usually so-so at the musical games, busts out w/ a ''phenomenal'' [[http://www.youtube.com/watch?v=1PiY9cq7NRQ bass verse]], stealing the scene from Wayne and Chip.
* Stephen Colbert's appearance. He was hilarious throughout but his CMOA was probably [[http://www.youtube.com/watch?v=1Bf769rvds4 Foreign Film.]] The fake language was German and since Colbert actually speaks German [[BilingualBonus every line he said was an actual German phrase]] including a line from one of Hitler's speeches ("Heute Deutschland, morgen die Welt!"/"Today Germany, tomorrow the world!").
** Wow, good thing the director didn't speak German...
* A nice pair of [[http://www.youtube.com/watch?v=qeGXUyGYu78&feature=related zingers between Colin and Wayne during a game of World's Worst TV Advertisements]].
-->'''Wayne:''' Order Colin Mochrie's guide to dialects in different countries! You get French, "HALLO!", Spanish, "HALLO!", Indonesian, "HALLO!"
-->'''Colin:''' Order the Wayne Brady surfboard- with a butt big enough to sit on!
* The episode with Creator/RobinWilliams as a whole. Awesome for Robin because he fit the show's format like a glove, and awesome for Ryan, Wayne and Colin because they managed to hold their own with ''Robin freakin' Williams,'' one of the most manic improvisors ever.
* One episode ended with Drew participating in a ''World's Worst'' "[[http://www.youtube.com/watch?v=0QnsaE9VjHQ priest or rabbi]]"; his impression of JerryLewis as a rabbi practically brought down the house.
* Denny Siegel makes the best Let's Make A Date guess of all time. You know you've scored one when you can get a reaction from Colin AND Ryan.
-->'''Denny (guessing Wayne, who's actually [[Film/StarWarsEpisodeIThePhantomMenace Jar Jar Binks]]):''' Wait a minute, bachelor number one, are you dating Creator/WoodyAllen?
-->'''Drew (after everyone else ''finally'' stops laughing):''' No, but that's a great guess, though.
* For Kathy Greenwood:
--> Drew: (reading) "Things You Can See From The Moon Other Than The Great Wall of China."
--> Kathy: "Hey look, those are Ryan's shoes!"
** One round of Song Styles has her [[spoiler: effectively humping Colin and Wayne in the chest - and Wayne loves it!]]
--> Drew: "I gotta say Kathy Greenwood, [[PetTheDog that was some of your best work!]]
** She actually [[spoiler: got a playing of Party Quirks ''completely right.'' Because it's a special occasion for Kathy, Drew gives her 3000 points.]]
* The [[http://www.youtube.com/watch?v=QAjTtNALURg game of Party Quirks]] where Colin is obsessed with confirming everyone's gender. His total commitment to this role sells it. Definitely CrossesTheLineTwice.
* During a game of "Props," Ryan and Drew are [[IncrediblyLamePun horsing around]] with horseshoe-shaped pink foam pads. Drew doesn't miss the chance for comedic gold and has Ryan play the appropriately-shaped [[ButtMonkey tall and skinny pole]] while Drew flings his "horseshoes" at him with granny-style tosses. Drew misses the first toss miserably. Not expecting to nail the second, he chucks it at Ryan's head... and gets it hooked around his neck. Cue cheering from the amazed crowd, Ryan smiling with utter humility (his expression says, "I can't believe he actually did it- and now I look like a fool again"), and a priceless look of sheer astonishment and happiness on Drew's face as he celebrates with a victory dance.
* After Richard Simmons has some fun in "Living Scenery," his insane, over-the-top antics have Ryan and Wayne laughing their asses off, Greg can barely contain himself from his seat, Colin, the hardest to crack out of the guys, has completely lost his composure, Drew's in tears from laughing so hard, and ''everyone'' in the studio audience is thrashing wildly with the greatest laughter ever triggered in one single show, something so rare and unprecedented it may very well be '''''the''''' funniest episode ''Whose Line'' ever spawned during the course of the whole series.
-->'''[[WebVideo/ToBoldlyFlee Luke Mochrie:]]''' That man [refering to his father, Colin] did things with Richard Simmons that no one else would do!
* Drew's comeback to a fat joke Ryan makes at the beginning of [[http://www.youtube.com/watch?v=UgU9o5n_U7k&feature=endscreen this video]]
-->'''Drew:''' A lot of people forget that on TheDrewCareyShow, Ryan and I have been totally naked.
-->'''Ryan:''' Of course, some of us needed a wide angle lens.
-->'''Drew:''' And some of us needed a ''zoom''.
* Ryan's incredibly moving (as well as [[FunnyMoments hysterical]]) monologue during [[http://www.youtube.com/watch?v=KOCJcFy6QsQ a game of Weird Newscasters]], in which he plays a demanding temperamental Hollywood actor trying to give an Oscar winning performance. Given the standing ovation he got from both the audience and other performers, he succeeded big time.
** Made even better when accompanied by [[http://www.youtube.com/watch?v=zWAZsjc73PM sad violin]].
* [[http://www.youtube.com/tJ2LYk6Fc1A This game of African Chant]] sung to Julia, a dance instructor who definitely stole the show when she started leading the performers with dance.

!!Second US version:
* Wayne was named an executive producer. He has a lot of good ideas, and he has given a lot to the show. He deserves it.
* While the first episode was good but a bit uneven, the second episode of the new CW version demonstrated that ''Whose Line'' has made a solid comeback with one of the funniest "Scenes From A Hat" rounds in series history. Clearly they needed that first episode for practice.
** The musical games have come back, with Laura Hall and Linda Taylor once again providing the music.
** They also brought a bunch of the old crew back. The buzzer even makes the same sound as before. It's like coming back home.
** During the Helping Hands segment, Ryan passes popcorn to special guest [[{{Glee}} Kevin McHale]] by pouring it into his own mouth and shooting it to Kevin's. [[http://youtu.be/n-T5AY8kA2M?t=1m47s Kevin catches one]]
** Also, by the third episode Aisha Tyler has started making Canada jokes and issuing joke points. While she's not as good as Drew yet, she's clearly opening up to the cast.
** The revival got [[http://seriesandtv.com/the-cw-renews-whose-line-is-it-anyway/13793 renewed for a second season]] within two weeks of its premiere, because of high ratings.
*** The first two episodes brought in an average of 2.96 million viewers (only one other show on the network that week managed to get over 1 million viewers) and averaged a 1.15 rating among viewers 18-49, whereas most shows on the network over the summer are lucky to get a 0.5 18-49 rating.
** Kyle Richards (from ''The Real Housewives of Beverly Hills'') doing the splits.
** In "What's in the Bag" in the first episode, Colin finds a pair of sunglasses in the bag, puts them on, and tells Wayne "Sorry, there's just a bit of a shine." That's right, ''[[TheDogBitesBack Colin]] [[RunningGag finally made a bald joke]] [[WhosLaughingNow at someone else's expense.]]''
* Speaking of which, the first Gary Anthony Williams episode. You can see him gesturing for Wayne and Colin to join him on stage for the "bad hairloss commercial" one. That's right, ''[[SelfDeprecation it was his idea.]]''
** In his next appearance, he scores another personal one by [[http://www.youtube.com/watch?v=eB0YXedbFwI&lc=L-R91ITfzuA1BWhBO95ikdjDp7_DeZanzcGVHYGD6o8 getting Wayne to corpse first]].
* The [[{{Glee}} Kevin McHale]] episode. Colin's claim of holding a note for 50 minutes may not actually pan out that way, [[http://www.youtube.com/watch?v=NMYMqEHUjHs but YOU try making one breath last 15 seconds.]]
* [[Series/HartOfDixie Wilson Bethel]] plays a doctor-themed Helping Hands with Ryan and Colin. Ordinarily, this is a game where Colin gets to shove potentially disgusting things into Ryan's mouth. [[https://www.youtube.com/watch?v=GQzoDfMwr10 Instead, Wilson shows what a good sport he is.]] Aisha actually ''cheers'' at the bravado.
* The Lisa Leslie episode.
** Ryan actually getting to work with a woman his size.
** Heather Anne was happy and honored to meet Lisa. It was a definite girl power moment for her.
* The second Nyima Funk episode, with Living Scenery. After Ryan brings up waffles, Nyima gets the idea to pose prettily and remain very still, giving Ryan the idea to treat her like [[http://www.savingmoneyinmissouri.com/wp-content/uploads//2013/08/tumblr_inline_ml8qu5S9821qz4rgp.jpg a particular brand of waffle syrup known for a distinctive bottle design.]] Possibly the only time you'll see one of the old guys follow the new guy's lead.
* Another one for the "Greatest of Greatest Hits" collection: Wayne and Jeff sing "Pulling Sally's Pigtails" as Music/KanyeWest and Music/NeilDiamond.
* One of the more recent episodes brought back the Irish Drinking Song, and well, let's just say that Colin Mochrie STILL got it after all these years!
** Similarly, the return of Hoedown, in particular, how excited Aisha was knowing that the fans had been waiting for it for so long (judging by the ''huge'' applause it got when it was announced), and that she'd get a front-row seat to the players having to suffer through [[SarcasmMode their favorite game in the world]].
* Linda Taylor played some [[https://www.youtube.com/watch?v=Sr5AIJ8So9E EPIC guitar riffs during the game of Dubbing with Jack Osbourne]]; Aisha even awarded her 5,000 points for it.
* Nyima Funk had a moment of awesome in the Scenes From a Hat where the topic was "Tattoos you don't want to discover on a new partner's body". Wayne said "Next rest area ten miles?" and without missing a beat... well, [[https://www.youtube.com/watch?v=W8KImnnDNg4 you gotta see it for yourself]]. I call this awesome instead of funny because she is so QUICK.
* One word: [[https://www.youtube.com/watch?v=Io3A8RZ4584 boing]]. Even Ryan said "What is happening here?" in the middle of it.
* I have performed in a choir full of a-holes, but [[https://www.youtube.com/watch?v=apsYgNfvqTI&t=2m06s never this literally]].
* If you're only familiar with Ryan's (or any of 'em really) ridiculous ElvisPresley impression, you may not be prepared for [[http://www.youtube.com/watch?v=PseU8YMKeJE Wayne's near-perfect rendition of Jailhouse Rock-era Elvis.]]
* [[TheBigBangTheory Kunal Nayyar's]] HeavyMetalScream.
** Also from that episode, Aisha interrupts Ryan's suggestion in Scenes from a Hat where he's playing a Doctor. Ryan glares at her, and says "he's in the middle of f***ing surgery."
* Ryan being a sperm cell in "Party Quirks" and tackling a "didn't want to come" joke. It got past the censors!
* Much like Wilson Bethel above, Padme Lakshmi from ''TopChef'' scores one when [[http://www.youtube.com/watch?v=ocw7txu7Abs&index=1&list=UUpXN5r_6wVW1SOmXg3km5gw she gamely eats something that Colin was going to feed to Ryan.]]
* The fans get one for following through on their calls for a revival, watching ''Whose Line?'' lovingly, and quickly earning the show a third season.
* I'm going to say the entire "sexy jobs" Scenes from a Hat, and pretty much that entire episode was a Crowning Moment of Awesome. This troper has never laughed so hard - maybe ever. From Wayne finally getting the best of Aisha with the waxing gag, to Jeff Davis milking a bull, to Wayne's impression of Stephen Hawking, to Jeff taking over the camera, Ryan taking over Aisha's buzzer, and Aisha herself smacking the buzzer with her chest... It transcended funny and went right for awesome.
* Gary Anthony Williams plays a British metal singer in a game of Duet. And pulls it off remarkably well!
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