* Dawson gets his CMOA when he ''shouts'' at Basil who is currently going through a HeroicBSOD:
-->"[[CallingTheHeroOut Dash it all, Basil, the Queen's in danger, Olivia's counting on us, we're about to be horribly splatted,]] [[GetAHoldOfyourselfMan and all you can do is lie there feeling sorry for yourself!]] I know you can save us. But if you've given up, then why don't we just set it off now and be done with it?!"
** Which is followed up by the perhaps the greatest CMOA in the movie. Basil snaps out of his HeroicBSOD and, [[XanatosSpeedChess within seconds]], forms a plan to escape the triggered DeathTrap. All the awesome of Franchise/SherlockHolmes and Franchise/{{Batman}} rolled into one!:.
--> '''Basil:''' "Heh. Set it off now." ({{beat}}) "Set it. Off. Now? Yes, ha ha! That is it! We'll set the trap off ''now''!"
** He gets out of disguise, and with great cheer says, "Thank you, Dawson. Smile, everyone!"
** Even without the context, this is still a moment of awesome, showing off just how CrazyAwesome Basil can be.
* Ratigan kills a drunk mouse for calling him a "rat."
-->"Oh, my dear Bartholomew, I'm afraid that you've gone and upset me. You know what happens when someone upsets me..."
* Also, Ratigan verbal-owning Basil. Creator/VincentPrice's maliciously cheerful voice makes it all the more awesome.
-->"Frankly, I expected you fifteen minutes earlier. Trouble with the chemistry set, old boy?"
-->"You have no idea what a ''delightful dilemma'' it was, trying to decide on the most apporpriate method for your demise. I had so many ingenious ideas, I didn't know which to choose! So... I decided... to use them all."
* Ratigan deserves one for listening to Basil press his BerserkButton and, judging by the look on his face, taking a lot of self-control not to jump on Basil and maul him right there.
--> "Ratigan, no-one can have a higher opinion of you than I do... ''and I think you're a slimy, contemptible sewer rat!''"
-->[Ratigan smiles calmly and closes his watch]
* The random cameo of Bill the Lizard from ''Disney/AliceInWonderland'' was pretty awesome.
* Ratigan threatens to [[YouHaveFailedMe feed Flaversham to Felicia]] if he doesn't finish the Queen robot in time. Flaversham then becomes so angry that he manhandles the in-progress robot in a way that causes it to squirt oil on Ratigan's coat. The following line ensues.
--> "You can do what you want with me! I won't be a part of this-this-this ''evil'' any longer!"
** Becomes a heartwarming moment combined with tearjerker when Ratigan realizes that Flaversham really is willing to die rather than commit this crime...and so instead threatens the life of his ''daughter'', after which Flaversham complies with Ratigan's demands.
* "''SEWER RAT!''" Complete with a finger-point that [[Franchise/AceAttorney Phoenix Wright]] himself would be proud of. It's a potent mix of Awesome, Heartwarming and Funny. Basil taking control of the robot queen and using it to give Ratigan a ''blistering'' TheReasonYouSuckSpeech while making the robot expose itself as such, Olivia happily reuniting with her father, and Dawson and even the Queen tying up Ratigan's henchman.
* The ending of the movie: not only did they play up the Reichenbach Falls story (complete with a DisneyDeath for their Holmes stand-in), but the way the movie changes from a madcap, comedic mystery into a breathtaking chase sequence, a climactic fight inside the ClockTower of Parliament, the NightmareFuel of Ratigan's [[VillainousBreakdown evil transformation]] into a [[NoHoldsBarredBeatdown crazed killer rat]], and finally Basil's [[IronicEcho clever usage]] of Big Ben striking to topple the villain to his death (all of it with a very effective musical score) is simply incredible. Most people who talk about the Disney Renaissance say it began with ''Disney/TheLittleMermaid'', but just as many contend that ''Disney/TheGreatMouseDetective'' should be the real beginning, or at least that the seeds of it were planted here. (The movie, while vastly entertaining, does perhaps pale a bit compared to what followed it.) This ending sequence may be one reason why it deserves such an inclusion.
** Plus, that sequence marked the first time CGI was used by the feature animation department. The gears were computer animated then traced by hand.
* [[PreMortemOneLiner "On the]] [[NotQuiteDead contrary...]][[MeaningfulEcho THE GAME'S NOT OVER YET."]]
* ''Olivia'' gets one [[PluckyGirl for calling Ratigan a rat]]! The last guy who did that got fed to a giant cat.
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