!!!Main series:
* [[http://www.nuzlocke.com/pokemonhardmode.php?p=12 "...That would be breaking the rules."]]
* Episode 29. Especially Doakes' [[spoiler:battle against Arcanine where he ditches Magnitude for Earthquake. AND ARCANINE SURVIVES!]]
* [[http://www.nuzlocke.com/pokemonhardmode.php?p=24 Buddy's transformation. This is how badasses are made.]]
** And [[http://www.nuzlocke.com/pokemonhardmode.php?p=44 here]] is Buddy's [[spoiler:death. [[GoOutWithASmile This]] is how badasses go out]].
* Bruce vs. Blastoise, complete with references to Batman, a flashback to how their doomed friendship began, and victory in the form of a Blast Burn straight to Blastoise's face. And then Ruby punches out Gary.
* The MookHorrorShow that takes place nearly every single time Ruby finds Team Rocket.
* In ''The First Movie'', Ash tries to punch Mewtwo and fails. Here, Ruby, with Sawyer's help, ''succeeds''.
* [[http://www.nuzlocke.com/pokemonhardmode.php?p=58 "Well, I've got freedom of repel."]]
* Luke handily winning Ruby his first wild Unova Pokemon.
* Blastoise gets a glorious TheDogBitesBack moment.
--> [[http://www.nuzlocke.com/pokemonhardmode.php?p=53 "Smell ya later."]]
* Ruby [[http://www.nuzlocke.com/pokemonhardmode.php?p=59 easily winning his first gym badge]], and promptly setting the gym on fire while saying a one-liner.
* Cheren [[http://www.nuzlocke.com/pokemonhardmode.php?p=60 ripping out a Plasma grunt's heart with his bare hands.]]
** The fact that Ruby and Cheren are actually fighting the Grunts with their bare hands rather than just settle it with their Pokemon. And that Ruby himself takes on grunts in nearly every game with his bare hands.
* Senor Fluf, the ButtMonkey of the group, finally gets his own moment of awesome. N's Pidove, who just [[spoiler: killed Hank]], is ready to attack Luke [[InTheBack from behind]]. Cue Senor Fluf's BigDamnHeroes moment and swatting the bird before the attack could land.
** Then in the next page [[spoiler: he finishes the Pidove off]].
* Ruby crashing Burgh's limo into Team Plasma's hotel room and making even Ghestis look like a fool, can be both this and CrowningMomentOfFunny.
* Ruby catching [[spoiler: the legendary Victini]] and promptly using it to give Burgh some nice payback.
* Ruby went through [[ThatOneBoss LENORA]] without losing a single Pokémon. Ruby went through the nightmare of PokemonBlackAndWhite Nuzlockers without a single pokemon going down.

!!!Hale's Emerald Hard Mode[=/=]Platinum Hard Mode:
* From Hale's fan comic, the entirety of Hale vs. Steven- not just the Pokemon, but the NoHoldsBarredBeatdown between the trainers. But really, the final move of the fight needs to be mentioned.
-->Fowler used--- '''''OVERHEAT!'''''
* Django's nearly soloing May's team also qualifies. Even though Hale pleads with him to stop fighting because he knows Django will die, Django ''demands'' to keep on fighting and nearly finishes off all of May's Pokemon [[spoiler: before succumbing to Swampert.]]

!!!Freddy's Nuzlocke Adventure:
* From Freddy's comic, the battle against Lance. Which happens to be fully animated.
* The fight against Koga in his Blue run deserves a mention too. [[spoiler: Connery survives A WEEZING SELF-DESTRUCTING.]]
* Connery's first appearance alone qualifies. He beats down two Mankeys ''Film/JamesBond'' style.
** Let's be honest, pretty much everything Connery does should be here.
** His [[spoiler:fake-out death]] in Koga's gym.
* How Freddy's Doduo uses Fly. An ancient Pokemon mystery solved.
* Vs. Squirtle.
* The entirety of the Elite 4/Rival battles.
* After the run concludes, Freddy states his intent to go off and beat other Nuzlocke challenges. After being informed that it's 1998 and there aren't any other games to Nuzlocke, he's reminded to take some batteries for his Game Boy. Freddy's reply? "Where we're going, we won't need batteries.", then ''LITERALLY GOES BACK TO THE FUTURE IN THE FREAKING DELOREAN.''
* [[http://www.youtube.com/watch?v=kR6kXwaEpJQ Marty finally begins to show just how strong he can truly be.]]

!!!Summers of Our Youth:
* [[http://fc09.deviantart.net/fs71/f/2011/023/7/9/emerald_nuzlocke__page_8a_by_umbrielle-d37x2es.png Heaven]] [[http://www.youtube.com/watch?v=HcfhQyLm-LE Express]].
** With that, Jig has cemented himself as the [[BigDamnHeroes best goddamn Zigzagoon]] in the history of Pokemon.

!!!Landwalker's Nuzlocke:
* The entire battle with Kyogre[[spoiler:'s and Archie's fused form]], culminating with "Well, how about that... I killed a god."
** Also, [[spoiler:ZIGZAGOON ARMY.]]
* Every Elite Four battle (and naturally the one against Steven) has a team member taking center stage.
** Against Sidney: Rikishi/Ninio tag team. The flames lighting the room go out at exactly the time the battle ends too.
** Against Phoebe: "Brobat is just about to notice... that you ripped his suit." Meanwhile, Lunatic takes out his foes without even waiting for an introduction.
** Against Glacia: The whole damn thing, especially figuring out Glacia's tricky strategy with ease.
** Against Drake: Gary the Gyarados. Just... yeah. On his own, and makes it such a short fight it doesn't even take the whole page.
** Against Steven: Hoo boy, where do we start? Every single member (with the sad but logical exception of Brobat) does something awesome. High points are Rikishi [[spoiler:taking a Hyper Beam for Ninio of his own accord even though it kills him]], Ninio's epic Fire Blast, and just... the final blow.
--->"Now! With all your might! End it! For everyone we've lost! For the team! For [[spoiler:Rikishi]]! LAUNCH THE FINAL BLOW! AND PROVE ONCE MORE THAT YOU ARE WORTHY OF THE NAME I HAVE GIVEN YOU! ''AVENGER!'' '''''LEAF BLADE!'''''"

!!!A Petty Nuzlocke Challenge:
* "This one's for the beaten down, the ones who lost their rock and roll..."
* Stopped short by Koga's invisible walls? Why, just have a Nidoqueen use Brick Break and destroy the whole thing!
** ...followed up by: "Hey, two words: COMPOUND EYES." Actually, Lulu is one of those Pokemon who just deserves a general entry and should have it left at that. As of this writing, the Butterfree in question has managed to survive to ''the beginning of Victory Road'' (and possibly further!) in a NUZLOCKE CHALLENGE. She got this far without fainting. That's one badass bug.
** And now she's gone and completely owned Bruno's Fighting-types. Seriously, holy crap.
** "'''''YOU DON'T KNOW JACK ABOUT BUTTERFREE!'''''"
* Vinny the Magneton immediately catapults himself straight into BRO-TIER.
---> "BRING IT, YA OVERGROWN FROZEN TURKEY!"
** Not to mention "[[NoSell STURDY BODY]] BIZZOYYYY!"
* After starting to be a bit overshadowed due to deaths and awesome new characters, Spuds the Venusaur goes full-on badass against Lorelei.
---> "[[PreMortemOneLiner Thanks for the shower.]] ''[[PreMortemOneLiner I needed the refresher.]]''"
** Let's clarify that: Spuds, a Grass-type which is weak to Ice attacks, went up against the ELITE FOUR MEMBER THAT SPECIFICALLY USES ICE POKEMON and still ended up KICKING ASS.
* The Agatha battle, ALL OF IT.
* At long last, the final battle with Gary. Locke only uses Nadine and Pongo for this match, ''and wins'' [[spoiler: though tragically, Nadine is lost to Gary's Charizard despite type advantage]]. Vengeance for James and Rick is had, and not a single iota of sympathy for Gary was given.
* The final battle against Mewtwo. [[spoiler:Locke catches Mewtwo with the Master Ball before Pongo can land the final blow. Mewtwo yells at Locke for not having the strength to finish him. So, this is the part where the hero shows her goodness and decency by sparing Mewtwo's li- oh wait, no, she takes the Master Ball and SMASHES IT AGAINST THE FREAKING WALL.]]
* During the Heart Gold Run, Petty's egg hatches into a Togepi that has a Shiny Leaf. First thing it does? Metronome against an Onix and lands JUDGEMENT!
* Broseph shines in the battle against [[ThatOneBoss Whitney]]. Even after being hit with attract, he just keeps on attacking without being stopped by infatuation. A suitable revenge after Miltank [[spoiler: killed Ichabod]].
-->'''Broseph''': Bros before hos.
** Likewise, Locke punching Whitney in the face after all the mockery directed at her and at Ichabod's death.
* Miki owning Rocket grunts in the dance hall as well as 5/6 of Locke's team evolving when they join the fight. Broseph gets to evolve ''twice''. This part of the playthrough was embellished for the sake of brevity, but still awesome plot-wise.

!!!Nonparael's Nuzlocke runs:
* The Elite Four battles in Pearl are basically an exercise in how to completely pwn the game. Note that, amongst Ara's team members, he had a Kricketune and a Cherrim. LethalJokeCharacter[=s=] indeed.
** Prior to Chopin the Kricketune, Ara had Clutterbug the Wormadam.
---> Only weakness? Fire. Rarest type in Sinnoh? Fire.
** Case in point with Cherrim, here is the [[http://nonparael.deviantart.com/gallery/26511630?offset=24#/d35cfk7 part in question]]. Even when facing very powerful ground and rock types with each displaying a NightmareFace, Alarune the Cherrim is smiling the whole time, even displaying a CatSmile. Cue to a SlasherSmile as Alarune drops raining Solar Beams onto the field, with Bertha's OhCrap expression sealing it.
* The E4 battles in Black are pretty rad as well. They basically can be summarized as "Soleil beats the shit out of everything (with occasional help from Flynn and Madotsuki)." They're completely defeated in one page.
* Fear gets a great one in the battle against Ghetsis when he protects Peep.
---> "You call that fire? I'll show you fire!" (roasts Eelektross)
** And then Peep shows that he's no slouch either by beating Ghetsis' Seismitoad. [[spoiler: Nineveh]] would be proud.
* N gets a good one in Dragonspiral Tower, when he announces that [[GoodIsNotDumb he knows damn well what Ghetsis is up to]], and he's planning to ''escape with Zekrom'' instead of taking over Unova, in order to derail his plot and force his hand. [[spoiler: [[BiggerBad The Glitch]] [[{{Railroading}} has other ideas]].]]

!!!Kynim's Nuzlocke runs:
* Bianca and Nina giving the Team Plasma members in the Dreamyard an epic NoHoldsBarredBeatdown for [[KickTheDog beating up the orphaned Pokemon]].
** The Musharna [[MindRape mind raping]] the two Plasma grunts right afterwards can also count. It is also arguably NightmareFuel.
* [[http://www.youtube.com/watch?v=iI8FGVvNA08&feature=related This moment]] from the Diamond run, which doubles as a CrowningMomentOfHeartwarming.
* Rex, finishing the lead Pokemon of a ThatOneBoss in one hit.
---> "Niko, eh? Hola.~ Say... want to hear a touching story? Once upon a time... ''you got beat.'' And I lived ''happily after.'' '''''The. End.'''''"
* Mimi got one that doubles as heartwarming during the battle with Lenora, after Nina recalls Jordan after he started taking a beating from Herdier Mimi comes out on her on and takes Herdier take down.
---> '''Mimi''':"I-I won't let you hurt anyone on our team or make Nina cry!"
* Who can forget the dual crowner of awesome and heartwarming? [[spoiler: Bianca's father appears and plans to force her back home with his Gurdurr, saying he doubts she would ever be a competent trainer. Then Elesa (AKA foxy lady who doesn't take your bullshit) comes and makes him back off and let go on her journey. He doesn't but before he can do a thing, ''all'' of Bianca's Pokemon come out and informs him how competent she really is by kicking his Gurdurr's ass. To top it off, Elesa takes the measure of ensuring Bianca's mother won't pay for what happened by immediately taking Bianca to report his abuse and getting them both help.]]
* [[PreAssKickingOneLiner "By the way, Skyla?]] [[TwoWordsObviousTrope Two Words.]] [[spoiler: [[CurbStompBattle Electro Ball]].]]
** Even more awesome is that it solidifies Andy's deserving of a spot in Nina's team by [[spoiler: [[TookALevelInBadass evolving into Galvantula and becoming the official electric type of her team to replace Jordan]]. [[BadassAdorable And he still makes emote faces]].]]

!!!Saber's Nuzlocke run:
* Candace has a LOT of these. Many of which also involve NightmareFuel.
** "I'm here to report one more casualty from Mahogany Town... [[spoiler: [[DramaticUnmask *Removes mask*]] Pryce's Dewgong.]]
* Whitney verbally ripping Giovanni a new one.
** Not to mention her and Candace's Pokemon taking down Team Rocket.
* A line that weds CrowningMomentOfAwesome with NightmareFuel:
---> [[spoiler: Wild [[AnimalMotif Zangoose]] used Crush Claw! Weavile fainted!]]
** Take note that, according to Saber, the word "fainted" is synonymous with "died" in this run. [[spoiler: CANDACE KILLED A WEAVILE WITH HER BARE HANDS.]]
* More... subdued than other moments in this run, but Giovanni calling out Silver for the foolishness of his revenge quest.
* [[spoiler: The super-powerful, super-crazy Dragonites under the shrine in the Dragon's Den awaken and attack. Frostbite the Jynx ONESHOTS THEM ALL WITH A SINGLE AVALANCHE.]]

!!!Whose Locke Is It Anyway?:
* Randy catching a Metang with a single regular Pokeball. Metang has a catch rate of '''3.'''

!!!Manic's Screenshot Runs:
* One happens in his [[http://s7.zetaboards.com/Nuzlocke_Forum/topic/8697353/1/ Platinum run]] during the Elite Four that just sends one into applause:
---> [[spoiler: '''''Nero tanks a crit Thunderbolt, going from 204 to 8 HP.''''']]
---> '''Nero:''' Seventy percent of the world's surface is covered in water, did you know that?
---> [[spoiler: '''Magmortar:''' Uh oh.]]
---> '''Nero:''' The human body is 60% water! Water can dissolve more substances than sulfuric acid! '''Most people use more than a hundred gallons every day! Water is my element, you barbaric oaf! You think that a [[spoiler: little zap]] can defeat me?!'''
---> [[spoiler: '''''Nero uses Surf and one-shots the magmortar.''''']]
---> '''Nero:''' '''''HERE! HAVE AN OCEAN!'''''
* Peace!Manic's first appearance in [[http://s7.zetaboards.com/Nuzlocke_Forum/topic/8742170/1/ Spirit Electrum]]. We go into his perspective for the first time when [[spoiler:Priscilla is killed by Lugia]], and the first thing that he does after realizing [[spoiler:her death]] is [[spoiler:''catching that bastard with a Master Ball'' while giving a ShutUpHannibal speech to go along with it.]] And this is after being hinted many times that Peace!Manic is a bit LighterAndSofter than War!Manic.
** The topic's grand reopening after it had been closed for unjust reasons.
** Dealing with Whitney's Miltank using just an Aipom. Never before has tickling proven so effective.
* Arthur the Scrafty [[spoiler: sweeping N's entire team.]]
* In Der Gnizalb, Cutman sweeping the entirety of Dr Wily's Team.
* Manic's HesBack moment in Dark Stars, accompanied by probably the most epic usage of "[[Manga/FistOfTheNorthStar Omae wa mo shindeiru]]" since the origin of the phrase itself.
* In Argent Ante, Dell's ENTIRE EXISTENCE! [[spoiler: Helps that he gets the ability Huge Power once he evolves into a Metagross.]]