* Right in the first episode, [[MundaneMadeAwesome the sausage scene]]. The mundane act of trying to stop food from falling on the floor, played out like an episode of ''Anime/DragonBallZ''.
** ''One. Two. Three.'' '''Safe.'''
* [[http://www.youtube.com/watch?v=ndmcRDWSj20 Yuuko and Mio's hallway chase scene in second episode.]]
-->'''Mio:''' [[PunctuatedForEmphasis I! Can't! Let! That! Happen!]] My life... IS ON FIRE!
* Yuuko and Mio arguing so hard in Episode 14 that it turns back into friendship. Doubles as a CrowningMomentOfHeartwarming.
* The Go-soccer match in Episode 19. Full stop.
* The entire battle with the Principal and the Deer, ending with the principal [[http://www.youtube.com/watch?v=ApKE01R9DyY SUPLEXING THE DEER.]]
* Mio [[OneHitKill one-hit KO-ing everyone]] (including a policeman and Sasahara's goat) over her drawings, [[http://www.youtube.com/watch?v=z30Y572EmCk as seen in Episode 16]].
* Mio vs the Airship crew in Episode 21.
* Yuuko and Mio's chase scene in Episode 25.
* Manga chapter 143: Mio's sister Yoshino meets Mai. Troll-on-Troll Combat ensues! [[spoiler:It's a draw]].
* Manga chapter 171: Yuuko resists one of the Professor's temper tantrums. How? By throwing an even ''bigger'' tantrum, then proceeding to distract the Professor with something nonsensical.