* [[spoiler:The end of the Dark Star Core/Dark Bowser battle. After Mario and Luigi destroy the Dark Star Core, Bowser finishes off Dark Bowser with five punches, the last one being the sliding punch that you cannot usually use in battle. After Dark Bowser explodes, he does the same victory pose and roar he does whenever he levels up.]]
** [[spoiler:Note that the Dark Star is an [[ArtifactOfDoom Artifact of Doom]] that's lived for probably ''thousands'' of years. '''[[DidYouJustPunchOutCthulhu And]] [[ButtMonkey Bowser]] [[DidYouJustPunchOutCthulhu just punched it so hard that it exploded.]]]]''' [[spoiler:And he didn't do it as Giant Bowser, or any other form - '''he literally destroyed Dark Bowser''' '''''with his bare fists.''''']]
* Bowser's moment of HeroicWillpower, with help from Starlow.
-->[[spoiler:'''Dark Bowser''']]: Soon, this kingdom will vanish along with all who dwell within. And you too will sleep eternally in the dark powers' embrace!
-->'''Bowser''': [[EvilLaugh GWAHAHA!]] [[CasualDangerDialog Great dark hurricane!]] Seriously, [[AmazingTechnicolorBattlefield perfect backdrop]] for an awesome [[FinalBoss final battle]]! [[LampshadeHanging You really sweat the details!]] Listen up! You're saying the kingdom will vanish? NOT TODAY! '''[[PreAssKickingOneliner THIS KINGDOM IS ALL MINE! SO YOU VANISH!]]''' [[FightWoosh *SHOWTIME!*]]
* It's a tie between the first time in ''Bowser's Inside Story'' that [[spoiler:The Mario Bros. have to revive Bowser and he turns giant as a result - and then proceeds to beat the stuffing out of '''his own castle''']] and in the beginning of the game when [[spoiler:Peach smacks Bowser halfway across the Mushroom Kingdom, quite literally]].
** Even better - in tune with some ContinuityPorn, [[spoiler:she uses her Wish power (see SMRPG and Paper Mario) and, together with Starlow, not only casts an Epic Level Drain, she also levitates him up, and with the tiniest hand movement, sends him flying. Clearly, [[BewareTheNiceOnes one does not bother the Princess when her Kingdom needs help.]]]]
** How about when Giant Bowser has to fight [[spoiler:Fawfulized Peach Castle, which has a freaking ''black hole gun'' that fires at the start of the battle, and again halfway through, and both black holes can suck in either Bowser or Fawful Castle, causing damage]]. The punch maneuver is your friend in the second half of this battle, [[spoiler:as a force field prevents fire damage to Fawful Castle after it takes about 50% damage. Hope you burninated the castle to get Refreshrooms beforehand.]]
*** The actual cutscene for this was also pretty awesome. Bowser growing about ten times larger, right outside of Toad Town, with all the Toads running around screaming "It's Bowser!" "Flee!"
* As Fawful [[spoiler: absorbs the power of the Dark Star]], he taunts Bowser about how powerful he is becoming, as he turns to a dark silhouette with red eyes. Then, Bowser steps forward and [[ShutUpHannibal smashes him in the face, sending him flying]].
* If you manage to defeat [[spoiler:[[BonusBoss Bowser X]]]], it becomes an awesome moment for you as the Emoglobin host will proclaim "You two, best globins ever!"
* It's relatively small, but hearing Bowser say Mario's name. It's not said through a chat bubble or a subtitle, but through his own [[EvilSoundsDeep deep]], [[BadassBaritone intimidating]] voice.