* WesternAnimation/BobTheBuilder OWNING Andrew W.K. in ''Destroy, Bob The Builder, Destroy'' is a good example.
** For a bonus, Andrew W.K is AdamWesting as himself.
* "Once Upon A Toon", no question. How does MAD celebrate Cartoon Network's 20th birthday? With a character from pretty much every classic show uniting [[FusionFall once]] [[CartoonNetworkPunchTimeExplosion again]]! Including JohnnyBravo, [[WesternAnimation/DextersLaboratory Dexter]], SamuraiJack, [[PowerpuffGirls Blossom]], even [[CodenameKidsNextDoor Numbuh 1]], and most of the time Cartoon Network just pretended KND didn't exist!
** And why did they unite? [[NetworkDecay To see who's behind Cartoon Network's downfall]]. Not to mention that Stu Syn-err...[[WesternAnimation/DextersLaboratory Dee Dee]] claimed that it was because they needed to make room for all new shows. And this aired the week of their 20th birthday. BitingTheHandHumor doesn't even BEGIN to describe this.
** Even better, Dee Dee's OverlyLongGag about showing a "sample" of ''MAD'' [[FramingDevice on a TV]], in a recursive, matrioska-esque way further hammers down the point about how MAD's pop-cultural nature is the only way the characters could possibly have been [[NetworkToTheRescue acknowledged]] and [[ReunionShow gathered.]] As a Youtube commenter pointed out, this is 50% BitingTheHandHumor, and (much more subtly) 50% [[TrollingCreator fan-trolling]]. And 100% awesome.
* Rio-A: Rio gains Green Lantern powers, and gives rings to other flightless birds (Mordecai, Big Bird, etc.) to save Jewel. Awesome way to kick of Season 2.
* The Fandom Nod in "My Little War Horse" with the cake that has "Go Bronies" on it.
* [[Film/{{Lincoln}} Lin]][[KingKong Kong]] vs [[TheIronGiant Mecha]][[TheIronLady Thatcher]]. Heck of a way to start off season 4.
** Speaking of starting off season four with a boom (or should we say, a sonic rainboom?), MAD co-aired that sketch with "[[WesternAnimation/MyLittlePonyFriendshipIsMagic Rainbow Dash]] [[Series/CrashAndBernstein and Bernstein,]] a definite CMOA for the brony community. While the FandomNod in "My Little War Horse" was awesome and the other sketches never made fun of it, this sketch ''centered'' around MLP's [[PeripheryDemographic male community]] in a positive light. But this line shows MAD has done their research:
--> '''Rainbow Dash''': ...I can show you how to be [[Memes/MyLittlePonyFriendshipIsMagic 20% cooler]] by being a brony!
** There's also the part where he was fighting dinosaurs.
-->'''President Linkong:''' [[BringIt Anybody ELSE have any "differing opinions"?]]
*** Let's just say Linkong in general was an awesome sketch.
* Even in a MAD sketch ([[IAmLegend I Am]] [[WesternAnimation/TheLorax Lorax]], to be specific) WillSmith is still badass
-->'''[[spoiler: Zombie!Lorax]]:''' The creatures of the forest seek revenge!
-->'''Will Smith:''' Well they can revenge on ''this!''
-->(''Takes a shotgun and blasts [[spoiler: zombie versions of [[RegularShow Mordecai and Rigby]], [[TheLooneyTunesShow Buggs and Daffy]], and [[ThePowerpuffGirls Mojo Jojo]].]]'')
* ''G.I.E.I. Joe''. They actually train ''farm animals'' to fight KOBRA.
* GeorgeWashington with DualWield axes fighting cherry trees. Yes.
* "Animal vs Appliance" Especially when animal wins
* LexLuthor brought [[LegionOfDoom his own cheering squad]].
* [[Film/{{Arthur}} Ar]]Film/{{Thor}} rescuing Jane ''DonkeyKong'' style.
* In the [[{{X-Men}} X-]][[TheExMentalist Mentalist]] sketch, Wolverine get a nice BaitAndSwitch interrogation.
-->'''Wolverine:''' Look, bub... [[Franchise/LawAndOrder in the criminal justice system, the people are represented by two separate yet equally important groups]]. (''SNIKT!'') Right claws, (''SNIKT!'') and left claws.