* Chapter 16: Wrex fights ''[[SuperMode Avatar State]] Shepard'' to a near standstill.
* Chapter 17: Shepard vs Sovereign and Saren. Both of them.
* Chapter 19: Shepard fights the Sovereign-possessed Saren with her crew's aid.
** Doubles as funny, Garrus crossing a Mass Relay. Usually reserved for spacecraft (and in this Relay's case, the Mako), he crossed it ''unprotected'', and made it to the other side in one piece.
* Chapter 31: James Vega and Anette, an Ardat-Yakshi, invade one of the Collector Ships and run into Leviathan. At first, he has the upper hand… Until Anette melds with him, claims about ''10 million'' of his composite souls, and proceeds to singlehandedly kill everything else on the ship till Leviathan stops her, and then prevent it from crashing after Leviathan ''cuts part of it away.''
** And in a lesser CMOA, Leviathan then, despite his portion of the ship ''not having engines'', apparently uses his biotics to accelerate to FTL drive.
* Chapter 37: during his Trial to become a shaman, Grunt encounters a Thresher Maw. Not only does he get it to back down, he ''tames it''.
** [[SugarWiki/FunnyMoments And then he names it Snot.]]
* Chapter 43: Morinth attempts to eat Shepard's soul... and discovers, in rapid order, that the Avatar Bequest is a DefenseMechanismSuperpower, gets pummeled mercilessly, and ''biotically fired into the Omega-4 Relay.''
* Chapter 44: Leviathan psychically executing Bulwark for trying to usurp him. He does so even though the latter was still in Dark Space.
* The attack on the Collector Base. All of it. Special mention goes to:
** Grunt [[SummonBiggerFish summoning his pet Thresher Maw]] to clear a path back to the ''Normandy''.
** Shepard energybends Leviathan and traps her in her original body, rendering her powerless.
** The turian armada vs. Leviathan's Reaper body (having gone berserk due to the aforementioned soul removal); let's just say the turians have much MoreDakka available than the Alliance did.
* Chapter 61: Grunt walks right up to the Tuchankan spirit of death, which even ''[[PhysicalGod Shepard]]'' is scared of, and convinces it to go kill Reapers.