* Actually [[NintendoHard winning]] [[LuckBasedMission the]] [[DidYouJustPunchOutCthulhu game]].
** Pat yourself on the back if you actually manage to literally [[DidYouJustPunchOutCthulhu punch out]] [[ThatOneBoss Cthulhu]].
* Kingsport adds otherworldy encounters where an investigator, if they are in the right place, must immediately fight an Ancient One. Alone. If they win, they immediately seal and close a gate. Bonus points if that's the gate that wins the game.
* Every enemy in the game has a modifier that subtracts how many dice you roll when fighting them, for example Cthulhu has -6. [[TopGod Azathoth]] himself has a ''negative infinity'' modifier. Not that it matters since he instantly destroys the earth as soon as he awakens.
* To a minor extent, completing any of the Personal Stories. All of them will grant positive effects to the characters, but some of them let the Investigator [[GetAHoldOfYourselfMan successfully overcome personal demons or doubts]], [[RoaringRampageOfRevenge deliver payback to monsters that have wronged them]], [[IWillFindYou save a loved one from mortal peril]] ([[IOweYouMyLife granting allies or special perks]]), or [[EleventhHourSuperpower unearth great powers that will be able to turn back the tide against]] the EldritchAbomination, all of which could mean the difference between SavingTheWorld, or TheEndOfTheWorldAsWeKnowIt.
* In ''Eldritch Horror'', Diana Stanley's special ability. To other investigators, Cultists are a nuisance that could become dangerous depending on the Ancient One. To Diana, they're weapons. She can send a Cultist anywhere she wants, or remove that Cultist along with ''every other non-epic monster on the space''.