[[quoteright:320:http://static.tvtropes.org/pmwiki/pub/images/3804_8762.jpg]]
A [[TwelveEpisodeAnime 13-episode anime series]] developed by RADIX and initially broadcast in 2003.

The plot is a bit difficult to wrap your brain around. In 2017, Earth satellites detect a gravitational anomaly coming from the direction of the constellation Lyra. When the signal is analyzed, it's revealed to be a transmission from the Voyager spacecraft, leading to the discovery of faster-than-light travel as well as a wormhole inside the core of Saturn's moon Titan. Others are soon discovered. Further exploration of these wormholes, or "inflation holes," results in the discovery, in the year 2197, of a planet ten parsecs from Titan which is dubbed the Quantum Core, which contains a wormhole identical to Titan's at its center and was apparently once occupied by a now-extinct alien species whose excessive use of wormhole travel resulted in the equatorial mass of the Core being burned away, leaving it in the shape of...well, [[ExactlyWhatItSaysOnTheTin an apple core.]]

Within 50 years, humanity has constructed a base on the Core, dubbed ''Watcher's Nest''. Not long after, an expedition beneath the planet's surface is attacked by a Ghoul - your garden-variety EldritchAbomination, origins and intentions unknown. The purpose of ''Watcher's Nest'' is now twofold: Monitor the Core, and prevent any further incursion from the Ghoul. Autopsies and genetic research conducted by a group called ''Alchemy'' reveal startling results when Ghoul genes are combined with animal DNA -- and later with human DNA, resulting in the project being officially closed down.

Now a new squad of cadets is brought on board ''Watcher's Nest'' to experience combat training, conspiracy and [[FanService absurdly tight uniforms]]. Misaki, our heroine, is hardly cut out for the job -- but trouble seems to find her, and she's being observed by parties unknown....

The original series was followed by a second 13-episode series, ''Divergence Eve: Misaki Chronicles'', in 2004. With the same set of characters and set in an alternative universe [[spoiler:that Misaki created at the end of the original show]], ''Misaki Chronicles'' is about the elite team at Watcher's Nest defeating Ghouls at different times in Earth's history.

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!!This anime provides examples of:

* ArtificialHuman: [[spoiler:Prim and LeBlanc]]
* AnachronicOrder: Confused by the first episode? You should be, as it takes place chronologically between episodes 12 and 13.
* AnimeHair: Compared to other animes the hair isn't too extreme but most defy physics.
* AntiVillain: Prim.
* ArtisticLicenseMilitary: Luke Walker is identified as a chief petty officer in early dialogue but his bio in the opening credits lists his rank as sergeant. And no, the Japanese words for the ranks aren't the same.
* BalloonBelly: Misaki in the ending.
* BarbieDollAnatomy: Averted with nipples but straight with the groin.
* BigNo: In episode 10 [[spoiler:Luxandra screams "no!" as she dies]].
* BridgeBunnies: Naturally, they bounce every time they turn around.
* ChristmasCake: Lyar von Ertiana, to her chagrin.
* ClothingDamage: Clothing, and especially space suits, seem to be made of wet tissue paper. [[spoiler: Every time Misaki transforms, her armor rips off, leaving her naked.]] How else do you expect to see as much cleavage as you do in here?
* ConspicuousCG: Some of the worst you'll ever see.
* CoolOldGuy: Wolfgang Woerns, commander of ''Watcher's Nest''.
* DeliberatelyMonochrome: Misaki's nightmare in episode 9.
* TheDragon: Prim Snowlight, to [=LeBlanc=]. Even though she isn't all ''that'' evil.
* EatenAlive: [[spoiler:Luxandra is devoured by a ghoul in episode 11.]]
* EldritchAbomination: The Ghoul is identified as a being from an AlternateUniverse that is able to cross into "our" universe because the wormholes used for FasterThanLightTravel pass through alternate universes on their way in, which apparently weakens the boundary.
* EmptyShell: [[spoiler:Misaki becomes this in the final episode after remembering "her" death.]]
* EvilutionaryBiologist: Dr. Kessler. Also [=LeBlanc=] - maybe.
* ExpendableClone: [[spoiler:The clone of Misaki who dies in episode one.]]
* {{Fanservice}}: Dear God in heaven. Every single female character save Kotoko is quite buxom and bouncy, and Misaki in particular gets a lot of underwear scenes and invariably ends up completely losing her flight suit [[spoiler:when she transforms]]
* FakeOutMakeOut: Invoked by Bernard.
* FrenchJerk: [=LeBlanc=].
* {{Gainaxing}}: Every plot-important woman save the TokenMiniMoe.
* GoMadFromTheRevelation: [[spoiler: Not so much as go mad as [=LeBlanc's=] head explodes]].
* GoryDiscretionShot: [[spoiler:When Luxandra is EatenAlive nothing is seen]] except the blood.
* IgnoranceIsBliss: "The truth doesn't always save somebody."
* ImmortalitySeeker: [[spoiler:[=LeBlanc's=] ultimate goal is to get unlimited power through the knowledge of the universe.]]
* IntrepidReporter: Subverted. Bernard Firestar turns out to be a complete ass [[spoiler:and gets himself shot by [=LeBlanc=].]]
* LaserGuidedAmnesia: This happens to anybody who leaves the military having learnt top secret information to stop it leaking. This happens to [[spoiler:Suzanna]].
* LatexSpaceSuit: Obviously.
* {{Mecha}}: Rampart Armor is a MilitaryMashupMachine of a roughly twice-human-sized mecha and a SpaceFighter, designed to fight both on the ground as a brawler/machine gunner and in zero gravity, with a detachable cockpit that acts as an EscapePod.
* {{Meganekko}}: Prim.
* MindControlDevice: [[spoiler:[=LeBlanc=] uses a microchip to control Misaki's body since her "heart is empty".]]
* TheMole: Bernard.
* MoodWhiplash: The end credits of the first series features imagery of Misaki frolicking in skimpy swimsuits set to a bouncy J-pop song, which invariably comes right after a dark sci-fi metaphysics moment.
* NietzscheWannabe: [=LeBlanc=].
* NoHuggingNoKissing: Except for the FakeOutMakeOut there's no touching at all. No romance either.
* NotUsingTheZWord: [[spoiler:They are zombies. "Energy is sent to their brains while their bodies remain."]]
* PeopleJars: Hundreds of them [[spoiler:kept by [=LeBlanc=] and, worst of all, they aren't dead.]]
* PutOnABus: And memory-wiped to boot, such as [[spoiler:Suzanna]].
* RidiculouslyHumanRobots: Kotoko-01. To the point that in one episode, she starts ''bleeding''.
* ScaryShinyGlasses: [=LeBlanc=], and sometimes Prim.
* SoundtrackDissonance: The ending theme of the first series and the opening theme of ''Misaki Chronicles'' are bouncy pop songs.
* {{Stripperiffic}}: Kotoko's pilot-suits in both seasons, the second even ''more'' so. Even her casual outfits tend to show a good amount of skin.
* TheStarscream: [[spoiler:Prim isn't all too happy about [=LeBlanc's=] plan and does try to ruin it for him.]]
* TheseAreThingsManWasNotMeantToKnow: [[spoiler: In the final episode [=LeBlanc=]]] learns of all the knowledge in the entire universe and their head explodes.
* TokenMiniMoe: Kotoko
* TomatoInTheMirror: It's obvious to the audience from the start that there's something ''special'' about Misaki. All in all [[spoiler:she's the second generation of generically altered humans (altered by the Ghoul) with makes them special in various ways. She is also a connection to the Ghouls.]]
** It also turns out that [[spoiler:Prim is one as well, but caused different results]].
* WiseBeyondTheirYears: Prim has several degrees.
* WorldOfBuxom: Every single female character apart from the flat-chested {{gynoid}} Kotoko is quite stacked and prone to {{Gainaxing}}. This is pure visual {{fanservice}} that plays zero part in the series' story.
* VaporWear: The training outfits the cadets wear. Also there's Kotoko's...''unusual'' style of pilot suits.
* YouGottaHaveBlueHair: Bernard and Misaki.
* YouKilledMyFather: Misaki towards Ghouls in general.
* YouKnowTooMuch: [[spoiler:[=LeBlanc=] says this before he kills Bernard]]: "The rat has entered the forbidden zone."
* YourHeadASplode: [[spoiler:[=LeBlanc=]]] in episode 13.
* ZettaiRyouiki: Misaki, Suzanna, Kotoko and Kiri.

!!''Misaki Chronicles'' contains the following tropes:
* BadassCape: Lyar's cape.
* BeethovenWasAnAlienSpy: Toyotomi Hideyoshi was a Ghoul.
* BrainUploading: [[spoiler:[=LeBlanc=]]] throughout the new universe is littered through the computer system and manages to control it. Eventually a host body is created.
* BrutalHonesty: After Lyar says a heartfelt farewell to Kurenai-no-ha when she returns to the sort of future, Kotoko finds out what would happen to him [[spoiler:he gets executed for trying to kill Toyotomi]]. She jokes about what would have happened had Lyar gone and helped him.
* ConvenientComa: Prim is in a coma throughout the series but she manages to [[spoiler:connect herself to the computers in time to fight against [=LeBlanc=]]].
* CuteGhostGirl: [[spoiler:The child version of the original Misaki... who was created by the original Misaki]].
* DeadPersonConversation: [[spoiler:Misaki with her dead father prior to the last episode]] which gives her a change of heart.
* FanServicePack: Kotoko
* FreudianExcuse: [[spoiler:[=LeBlanc=]]] has mother issues.
* GhostMemory: 1595-Misaki gets the memories of dead people. [[spoiler:She experiences the death of the original Luxandra, because that was sort-of in the past]].
* DistantFinale: Lyar is shown to be somewhere in her fifties and [[spoiler:finds Misaki (the same age but no longer a ghost) again]].
* INeverToldYouMyName: [[spoiler: Lyar asks Kurenai-no-ha how he knew her name; he says that he heard Kotoko say it, which was a lie]].
* LaserGuidedAmnesia: [[spoiler:Suzanna]]'s previously erased memories are restored.
* MilitarySchool: Part of ''Misaki Chronicles'' takes place during the characters' training in the alternative universe.
* MindScrew: They're travelling to the past of an alternative world while also being [[spoiler:trapped outside of time]]... It gets complicated.
* {{Samurai}}: Kurenai-no-ha.
* PastLifeMemories: [[spoiler: The new Misaki remembers her previous self from the original anime]].
* RetGone: After [[spoiler:sending Lyar, Kotoko, and Suzanna back to the correct universe after she gets trapped, Misaki]] effectively does this to herself. [[spoiler:Lyar]] is the only one who remembers her.
* SetRightWhatOnceWentWrong: [[spoiler:Misaki]]'s goal is to save loads of people from dying in this new timeline, trying to find an alternative world "without sadness". She comes to the conclusion that this isn't possible.
* TrappedInThePast: There's a time limit for how long the barrier around Earth will remain open. If they stay too long whoever went down would become trapped. Though really [[spoiler:the original Watcher's Nest has become trapped outside of time and has overlapped with another part]].
* VaporWear: Kotoko again.
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