[[quoteright:320:http://static.tvtropes.org/pmwiki/pub/images/3804_8762.jpg]]
A [[TwelveEpisodeAnime 13-episode anime series]] developed by RADIX and initially broadcast in 2003.

The plot is a bit difficult to wrap your brain around. In 2017, Earth satellites detect a gravitational anomaly coming from the direction of the constellation Lyra. When the signal is analyzed, it's revealed to be a transmission from the Voyager spacecraft, leading to the discovery of faster-than-light travel as well as a wormhole inside the core of Saturn's moon Titan. Others are soon discovered. Further exploration of these wormholes, or "inflation holes," results in the discovery, in the year 2197, of a planet ten parsecs from Titan which is dubbed the Quantum Core, which contains a wormhole identical to Titan's at its center and was apparently once occupied by a now-extinct alien species whose excessive use of wormhole travel resulted in the equatorial mass of the Core being burned away, leaving it in the shape of...well, [[ExactlyWhatItSaysOnTheTin an apple core.]]

Within 50 years, humanity has constructed a base on the Core, dubbed ''Watcher's Nest''. Not long after, an expedition beneath the planet's surface is attacked by a Ghoul - your garden-variety EldritchAbomination, origins and intentions unknown. The purpose of ''Watcher's Nest'' is now twofold: Monitor the Core, and prevent any further incursion from the Ghoul. Autopsies and genetic research conducted by a group called ''Alchemy'' reveal startling results when Ghoul genes are combined with animal DNA -- and later with human DNA, resulting in the project being officially closed down.

Now a new squad of cadets is brought on board ''Watcher's Nest'' to experience combat training, conspiracy and absurdly tight uniforms. Misaki, our heroine, is hardly cut out for the job -- but trouble seems to find her, and she's being observed by parties unknown....

The original series was followed by a second 13-episode series, ''Divergence Eve: Misaki Chronicles'', in 2004. With the same set of characters and set in an alternative universe [[spoiler:that Misaki created at the end of the original show]], ''Misaki Chronicles'' is about the elite team at Watcher's Nest defeating Ghouls at different times in Earth's history.

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!!This anime provides examples of:

* AnachronicOrder: Confused by the first episode? You should be, as it takes place chronologically between episodes 12 and 13.
* AnimeHair: Compared to other animes the hair isn't too extreme but most defy physics.
* BalloonBelly: Misaki in the ending.
* BarbieDollAnatomy: Averted with nipples but straight with the groin.
* BlondGuysAreEvil: Jean-Luc [=LeBlanc=].
* BigNo: In episode 10 [[spoiler:Luxandra screams "no!" as she dies]].
* BridgeBunnies: Naturally, they bounce every time they turn around.
* ChristmasCake: Lyar von Ertiana, to her chagrin.
* ClothingDamage: Misaki's armour rips off her, leaving her naked.
* ConspicuousCG: Some of the [[strike: worst]] [[strike: best]] uniquest you'll ever see.
* CoolOldGuy: Wolfgang Woerns, commander of ''Watcher's Nest''.
* DeliberatelyMonochrome: Misaki's nightmare in episode 9.
* TheDragon: Prim Snowlight, to [=LeBlanc=]. Even though she isn't all ''that'' evil.
* EatenAlive: [[spoiler:Luxandra]].
* EldritchAbomination: The Ghoul.
* EmptyShell: [[spoiler:Misaki becomes this in the final episode after remembering "her" death.]]
* EvilutionaryBiologist: Dr. Kessler. Also [=LeBlanc=] - maybe.
* [[spoiler:ExpendableClone: The clone of Misaki who dies in episode one.]]
* {{Fanservice}}
* FakeOutMakeOut: Invoked by Bernard.
* FrenchJerk: [=LeBlanc=].
* {{Gainaxing}}: Every plot-important woman save the TokenMiniMoe.
* GoMadFromTheRevelation: [[spoiler: Not so much as go mad as [=LeBlanc's=] head explodes]].
* GoryDiscretionShot: [[spoiler:When Luxandra is EatenAlive nothing is seen]] except the blood.
* HumongousMecha: Rampart Armor.
* IgnoranceIsBliss: "The truth doesn't always save somebody."
* ImmortalitySeeker: [[spoiler:[=LeBlanc's=] ultimate goal is to get unlimited power through the knowledge of the universe.]]
* IntrepidReporter: Subverted. Bernard Firestar turns out to be a complete ass [[spoiler:and gets himself shot by [=LeBlanc=].]]
* LaserGuidedAmnesia: This happens to anybody who leaves the military having learnt top secret information to stop it leaking. This happens to [[spoiler:Suzanna]].
* LatexSpaceSuit: Obviously.
* {{Meganekko}}: Prim.
* MindControlDevice: [[spoiler:[=LeBlanc=] uses a microchip to control Misaki's body since her "heart is empty".]]
* TheMole: Bernard.
* NietzscheWannabe: [=LeBlanc=].
* NoHuggingNoKissing: Except for the FakeOutMakeOut there's no touching at all. No romance either.
* [[spoiler:NotUsingTheZWord: They are zombies. "Energy is sent to their brains while their bodies remain."]]
* PeopleJars: Hundreds of them [[spoiler:kept by [=LeBlanc=] and, worst of all, they aren't dead.]]
* PutOnABus: And memory-wiped to boot, such as [[spoiler:Suzanna]].
* RidiculouslyHumanRobots: Kotoko-01. To the point that in one episode, she starts ''bleeding''.
* ScaryShinyGlasses: [=LeBlanc=], and sometimes Prim.
* SoundtrackDissonance: The ending theme of the first series and the opening theme of ''Misaki Chronicles'' are bouncy pop songs.
* {{Stripperiffic}}: Kotoko's pilot-suits in both seasons, the second even ''more'' so. Even her casual outfits tend to show a good amount of skin.
* TheStarscream: [[spoiler:Prim isn't all too happy about [=LeBlanc's=] plan and does try to ruin it for him.]]
* TheseAreThingsManWasNotMeantToKnow: [[spoiler: In the final episode [=LeBlanc=]]] learns of all the knowledge in the entire universe and their head explodes.
* TokenMiniMoe: Kotoko
* TomatoInTheMirror: It's obvious to the audience from the start that there's something ''special'' about Misaki. All in all [[spoiler:she's the second generation of generically altered humans (altered by the Ghoul) with makes them special in various ways. She is also a connexion to the Ghouls.]]
** It also turns out that [[spoiler:Prim is one as well, but caused different results]].
* WiseBeyondTheirYears: Prim has several degrees.
* VaporWear: The training outfits the cadets wear. Also there's Kotoko's...''unusual'' style of pilot suits.
* YouGottaHaveBlueHair: Bernard and Misaki.
* YouKilledMyFather: Misaki towards Ghouls in general.
* YouKnowTooMuch: [[spoiler:[=LeBlanc=] says this before he kills Bernard]]: "The rat has entered the forbidden zone."
* YourHeadASplode: [[spoiler:[=LeBlanc=]]] in episode 13.
* ZettaiRyouiki: Misaki, Suzanna, Kotoko and Kiri.

!!''Misaki Chronicles'' contains the following tropes:
* BadassCape: Lyar's cape.
* BeethovenWasAnAlienSpy: Toyotomi Hideyoshi was a Ghoul.
* [[spoiler:BlondGuysAreEvil]]: [[spoiler:Jean-Luc [=LeBlanc=] is the villain again]].
* BrainUploading: [[spoiler:[=LeBlanc=]]] throughout the new universe is littered through the computer system and manages to control it. Eventually a host body is created.
* BrutalHonesty: After Lyar says a heartfelt farewell to Kurenai-no-ha when she returns to the sort of future, Kotoko finds out what would happen to him [[spoiler:he gets executed for trying to kill Toyotomi]]. She jokes about what would have happened had Lyar gone and helped him.
* ConvenientComa: Prim is in a coma throughout the series but she manages to [[spoiler:connect herself to the computers in time to fight against [=LeBlanc=]]].
* CuteGhostGirl: [[spoiler:The child version of the original Misaki... who was created by the original Misaki]].
* DeadPersonConversation: [[spoiler:Misaki with her dead father prior to the last episode]] which gives her a change of heart.
* FanServicePack: Kotoko
* FreudianExcuse: [[spoiler:[=LeBlanc=]]] has mother issues.
* GhostMemory: 1595-Misaki gets the memories of dead people. [[spoiler:She experiences the death of the original Luxandra, because that was sort-of in the past]].
* DistantFinale: Lyar is shown to be somewhere in her fifties and [[spoiler:finds Misaki (the same age but no longer a ghost) again]].
* INeverToldYouMyName: [[spoiler: Lyar asks Kurenai-no-ha how he knew her name; he says that he heard Kotoko say it, which was a lie]].
* LaserGuidedAmnesia: [[spoiler:Suzanna]]'s previously erased memories are restored.
* MilitarySchool: Part of ''Misaki Chronicles'' takes place during the characters' training in the alternative universe.
* MindScrew: They're travelling to the past of an alternative world while also being [[spoiler:trapped outside of time]]... It gets complicated.
* {{Samurai}}: Kurenai-no-ha.
* PastLifeMemories: [[spoiler: The new Misaki remembers her previous self from the original anime]].
* RetGone: After [[spoiler:sending Lyar, Kotoko, and Suzanna back to the correct universe after she gets trapped, Misaki]] effectively does this to herself. [[spoiler:Lyar]] is the only one who remembers her.
* SetRightWhatOnceWentWrong: [[spoiler:Misaki]]'s goal is to save loads of people from dying in this new timeline, trying to find an alternative world "without sadness". She comes to the conclusion that this isn't possible.
* TrappedInThePast: There's a time limit for how long the barrier around Earth will remain open. If they stay too long whoever went down would become trapped. Though really [[spoiler:the original Watcher's Nest has become trapped outside of time and has overlapped with another part]].
* VaporWear: Kotoko again.
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