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* Tricia Holmes from ''WesternAnimation/{{Sixteen}}'' is well known by the gang as the most popular girl at their school and is the snooty archnemesis of Caitlin Cooke, who used to be a member of her GirlPosse.
%%* Tami from ''WesternAnimation/TheAmazingSpiez'', albeit [[LovableAlphaBitch frequently likeable]].
%%* Masami from ''WesternAnimation/TheAmazingWorldOfGumball''.
* Subverted on ''WesternAnimation/AmericanDad'' where the "hottest girl in school" and head cheerleader Lisa Silver appears willing to go out with the nerdy Steve and is surprisingly understanding when the show's antics keep messing up the planned dates. In another episode, it ''looks'' like she and her GirlPosse did something terrible to Steve's unpopular girlfriend... but it turns out it is actually Steve's friends who are responsible, once again subverting what you'd expect from Alpha Bitch behavior.
* ''WesternAnimation/{{Amphibia}}'' has Sasha Waybright, Anne's snobby and manipulative {{Toxic Friend|Influence}} who has a strong desire to rule over and control others; she even says herself that she ruled her school back on Earth. Anne starts the show off as her unwitting minion, being encouraged to engage in delinquent behavior and the like. As the series progresses, [[spoiler:Sasha ultimately drives Anne away from her, especially after the latter realizes how bad of a friend she really is.]] By the third season, however, [[spoiler:Sasha comes to [[HeelRealization realize how horrible she was]] and [[CharacterDevelopment grows out of this behavior to become a better person]]]].
* Nanette Manoir from ''WesternAnimation/AngelaAnaconda'', also a {{Fauxreigner}} FrenchJerk and something of a teacher's pet. Angela has had many an ImagineSpot where she gets thoroughly humiliated and/or maimed.
* Priscilla and Penelope Pinkpaws from ''WesternAnimation/AngelinaBallerina''.
* Cora, the daughter of the CEO Nora Rita Norita, in the ''WesternAnimation/Animaniacs2020'' short "My Super Sour 16" is an arrogant, spoiled RichBitch who wants her Sweet 16 to be absolutely perfect.
* Muffy from ''[[WesternAnimation/{{Arthur}} Arthur]]'' used to be this and occasionally still has shades of it, particularly in the episode where Arthur starts acting like her. However, [[LovableAlphaBitch she]] has a HiddenHeartOfGold.
* ''WesternAnimation/AsToldByGinger'':
** Miranda Kilgallen is [[BetaBitch the second-in-command]] and the GirlPosse leader to [[LovableAlphaBitch Courtney Gripling]]. She also [[DefrostingIceQueen defrosts a little]]. She never exactly becomes friendly, but she's a lot worse at the start than she is at the end.
** Courtney Gripling is an inversion -- LovableAlphaBitch. She's the queen bee; pretty, rich, popular, and more than a little narcissistic, a (self-proclaimed) snob, but she's a genuinely sweet person who doesn't seem to harbor any malice towards anyone -- unlike her friend Miranda. While her sidekick Miranda is quick to insult the unpopular girls, Courtney is friendly with them.
* Penelope Lang in ''WesternAnimation/AtomicBetty''. Her two lackeys are a pair of sycophantic nerds, and she is infamous for referring to people as "losers" often.
* ''WesternAnimation/{{Barbie}}'':
** Raquelle from ''WesternAnimation/BarbieAFairySecret'', although once the plot gets into motion, it's mostly pushed by the wayside.
** Violet Nylund and Ashlynn Torescu from ''WesternAnimation/BarbiePresentsThumbelina''.
* Formerly Sloane, Hallie, and Dua for Camp Pop and Olivia and her friends for Camp Royalty from ''WesternAnimation/BarbieInRockNRoyals''.
* Tammy Bounceaway from ''WesternAnimation/BarbieDreamhouseAdventures''.
* Tanya Butaire from ''Toys/LegoFriends''.
* ''WesternAnimation/BatmanBeyond'' has Blade and Chelsea. Blade is actually fairly apathetic, but has the look down pat, and is more than content to do things such as throw most of a school assignment on Terry, or manipulate a classmate to make another guy jealous. Chelsea, [[LovableAlphaBitch is usually a lot more sympathetic]]; she's actually a rather nice person, as seen in "The Last Resort," and except for being dismissive of Howard Groote, doesn't really do anything bad. Though she sometimes tries to get Dana to see other guys, it's because she thinks Terry isn't good for Dana, due to him always brushing her off.
* Claire Brewster in ''WesternAnimation/{{Beetlejuice}}'' who is still the "stuck-up, shallow yet very pretty girl" type.
* ''WesternAnimation/TheBenedictExpress''
** Madison, while [[AntiHero technically a protagonist]], is essentially the [[BetaBitch Beta Bitch]] to Alpha Bitch Erica Green and has often participated in her schemes against less attractive girls. [[ScrewTheRulesIHaveConnections Her status as the daughter of a professor]] allows her to get away with anything. Of course, their rival Sarah who is rarely shown is an even bigger Alpha Bitch.
** Ciara Toler, when she was in high school and before she was [[RapeAsBackstory brutally raped]] as a consequence of her bitchiness. While she showed strong Alpha Bitchy traits partly because of her status as "Barbee Creek Barbie" and "[[AlliterativeTitle the princess of the projects]]" - the most attractive girl in her 'hood - her snobbishness is portrayed somewhat sympathetically as arising from her impatience with living in a community filled with people who preferred to wallow in poverty and being the only person (even in her own family) with a drive to improve herself. In fact, she often tried to act more like a [[CuteSportsClubManager Cute Sports Club Manager]] and uplift the spirit of her friends and neighbors before becoming exhausted with the fact they were only interested in drug dealing and violence.
* Tammy Larson from ''WesternAnimation/BobsBurgers'' is something of a subversion in that she ''thinks'' she's an AlphaBitch and assumes she's super popular. The thing is, she doesn't have anywhere near as many friends or followers as you think she would if she ''were'' that popular. The only person who hangs around her on a regular basis and actually seems to like her is her BetaBitch Jocelyn, and even she doesn't seem to like Tammy that much. The only other people who could possibly be considered her friends are Jimmy Jr., Zeke, and the Belcher siblings, and that should tell you something about her popularity level since they don't seem to actually even [[TheFriendNobodyLikes like her]].
* ''WesternAnimation/BoyGirlDogCatMouseCheese'': Girl has a nemesis called Lila, who mockingly calls her "the queen of nerds" and threatens to shut down Girl's after-school cosplay club if elected school president, just to be mean.
* Nina Harper from ''WesternAnimation/{{Braceface}}''. Interesting, though, in that she and the protagonist, Sharon Spitz, were actually best friends when they were little. But a mishap with one of Nina's dolls that got its head popped off ended their friendship when she accused Sharon of being the culprit (even though she had no proof that Sharon did it). So her bullying Sharon is more or less out of spite. They do somewhat reconcile as the series goes on. Especially by season 3 when [[spoiler: it's revealed that Sharon was indeed innocent of the doll incident; Nina's cousin was the cause of that.]]
%%* Dawn Swatworthy from ''WesternAnimation/TheBuzzOnMaggie''. Unlike Maggie who does act selfish at times, she has zero redeeming qualities.
%%* Missy and Prissy from the ''Toys/CabbagePatchKids'' specials.
* Suzi from ''WesternAnimation/CampLakebottom'' is [=McGee=]'s vain and bossy sister, a former pageant queen, and a huge AttentionWhore.
* Cleo from ''WesternAnimation/CloneHigh''. She is a very selfish, snobby, cynical, vain, manipulative, pretentious, and materialistic stereotypical school diva who cares only about her social image, beauty, and popularity. Like in many a high school story, protagonist Abe has a hopeless crush on her despite the fact she's clearly more interested in JerkJock JFK.
** Come the revival series set in 2023, Cleo expects she'll still be the most popular girl in school and is utterly horrified to learn she's been replaced by Frida Kahlo, an artsy skateboarder with a slight mustache and a giant unibrow. In fact, Frida and Harriet Tubman think Joan of Arc is cooler than Cleo.
* Elisabeth "Sissi" Delmas in ''WesternAnimation/CodeLyoko'' is a strange version of this. In the first season, this is played straight, with the exception of a few scenes in only a few episodes. However, her assistance to the heroes in later seasons, particularly the second and fourth, is often offered without a second thought or a specific request for a reward, though this can happen quite a bit in a life-or-death situation. It seems that [[DependingOnTheWriter her personality alternates between seasons]], from a straight Alpha Bitch with several PetTheDog moments in Seasons 1 and 3 to a more JerkWithAHeartOfGold LovableAlphaBitch in Seasons 2 and 4.
* Paulina from ''WesternAnimation/DannyPhantom''. The most popular girl in school and loves to rub it in people's faces.
** The show also had Valerie Grey, who early in the show ends up losing her wealth and becoming a FallenPrincess. She still retained some bitchiness before completely mellowing out and becomes a villain towards Danny’s ghost half.
* Played with on ''WesternAnimation/{{Daria}}.'' You'd think the title character would have one as an arch-nemesis, but no, girls like [[PomPomGirl Brittany]] are generally nice ([[InnocentlyInsensitive if condescending]]) to her. Daria's sister Quinn, however, is part of the Fashion Club, the popular GirlPosse of their grade...and is in constant competition with its leader Sandi for dominance. Essentially, the two never have time to torture less popular girls because [[WithFriendsLikeThese they're torturing each other instead]]. Quinn is generally the more sympathetic of the two, if only because she doesn't abuse poor [[ExtremeDoormat Stacy]], the group's [[TheFriendNobodyLikes least popular member]].
** The longer the show went on, the more it seemed like Sandi was a {{Deconstruction}} of the Alpha Bitch. While the boys of Lawndale all see Sandi as hot, there was nothing to indicate Sandi truly was as popular as she believes she is. Since she spends far more time battling Quinn for supremacy in the Fashion Club, Sandi's supposed popularity only ever was apparent within the confines of the club. Furthermore, when she decides to quit in "Fat Like Me" only Quinn appears sorry that Sandi's leaving while Tiffany and Stacy seemed overjoyed at the thought of Sandi no longer breathing down their necks. Considering Sandi is repeatedly shown to be an egotistical and manipulative AttentionWhore, it's no wonder she's desperate to maintain what little foothold of popularity she has in a space she has total control over.
* Kimmie [=McAdams=] on ''WesternAnimation/{{Detentionaire}}'', leader of The Glamazons, is the classic rich and haughty girl who sits at the top of the popularity food chain. Her mother is even the head of A. Nigma High's Parents' Council and head of a MegaCorp. However, we eventually learn that she wasn't always like this, and [[spoiler:she steadily thaws out as she slowly starts to rekindle her childhood friendship with Biffy Goldstein and becomes increasingly involved in the show's story.]]
* [[AnIcePerson Jessica the Ice Witch]] from the ''WesternAnimation/DoraTheExplorer'' special "Dora's Ice Skating Spectacular". She gets better when Dora [[DefeatMeansFriendship becomes her friend]].
* Trixie Tang of ''WesternAnimation/TheFairlyOddParents'' is rich and popular AND lusted after by everyone, including Timmy, the main character. However, in the episode "The Boy Who Would Be Queen," a genderbent Timmy learns that there is another side to Trixie -- [[GirlyGirlWithATomboyStreak a boyish side that likes comics and video games]], which would shock all of the people who worship her. She says that all she wants for her birthday is a friend who understands this, but when Timmy arrives at her party and makes the offer, she saves face.[[note]]It's possible that this side of her personality is hinted at in ''The Big Superhero Wish!'' and ''Wishology''. In both specials, she apparently enjoys being in action scenes.[[/note]]
* ''WesternAnimation/FamilyGuy'':
** Connie D'Amico is the walking stereotype of the Alpha Bitch. She goes out only with popular boys, bullies anyone that isn't popular like her (mostly Meg), and is willing to make an unpopular boy popular just to prove that only she can make anyone popular, and that she can be the girl who dated every single popular boy. Even though [[LaserGuidedKarma karma has bitchslapped her several times]], she still goes around making everyone miserable at school. It's especially glaring since not only is she mean to Meg, but Brian [[TheReasonYouSuckSpeech spells out how her life is going to turn out and predicts she'll "hit the wall" at age 19]]. This sends her running off crying.
** Lois Griffin was one back in high school, pulling a [[Literature/{{Carrie}} Chris Hargensen]]-level prank on a chubby girl. Interestingly, her subsequent life turned out much like Brian's aforementioned prediction of Connie's life.
* Andrea Davenport from ''WesternAnimation/TheGhostAndMollyMcGee'' is a snooty tween "influencer" who tries to make Molly a pariah on her first day at school [[DisproportionateRetribution just because she kept mispronouncing Andrea's name]] (which she insists is [[PronouncingMyNameForYou pronounced "AHN-dree-ah" and not "ANN-dree-ah"]]).
* Pacifica Northwest from ''WesternAnimation/GravityFalls'', which is later {{deconstructed|Trope}} in season 2 when it's suggested she's only this way because her rich parents are even worse and raised her to be stuck up. She begins to {{defrost|ingIceQueen}} as of "[[Recap/GravityFallsS2E3TheGolfWar The Golf War]]", then "[[Recap/GravityFallsS2E10NorthwestMansionMystery Northwest Mansion Mystery]]" reveals that [[spoiler: she wasn't raised to be a bitch, she was ''mentally abused'' into being one. To put things in perspective, Pacifica was nothing more than a bully and a brat, but she isn't a sociopath. Dipper convinced her that there is still redemption for her]].
** "[[Recap/GravityFallsS2E3TheGolfWar The Golf War]]" had Mabel lampshade this by calling her a "walking one-dimensional bleach blonde ValleyGirl stereotype".
* Mindy from ''WesternAnimation/TheGrimAdventuresOfBillyAndMandy'' is a much younger Alpha Bitch, as well as an incredibly obsessive one. For example, she loses her [[CruelCheerleader head cheerleader]] position to Mandy (who just shouts the game plans to the team) and, after consulting the "patron saint of cheerleading" (a trophy she thinks is talking), decides the best solution is to incapacitate her in some way in the middle of a match, or, failing that, ''blow her up''. If she sees Mandy with anyone aside from Billy or Irwin or the like, she walks up to them, puts on an obscenely perky face, and says "You're my ''best'' friend!"
* Trina Riffin from ''WesternAnimation/{{Grojband}}'' acts this way, even though she only has one dedicated underling, her much put-upon childhood friend Mina. Nonetheless, [[AllThereInTheManual her official bio]] states her to be the most popular girl at her school (although since we rarely ever see the characters at school, this never pops up in the series).
* Paige Logan from ''WesternAnimation/{{Grossology}}''. She is a popular but very snobbish girl.
%%* Carla Cabrera and Melanie Melisma from ''WesternAnimation/GrowingUpCreepie''.
* ''WesternAnimation/HarveyStreetKids'':
** Frufru, the local {{rich|Bitch}} girl. She's depicted as being haughty, [[ItsAllAboutMe self-absorbed]], and into fashion, but lacks a GirlPosse, indicated to be simply because [[NoSocialSkills she's so distant from the other kids]].
** Zoe, Audrey's [[BigBrotherBully abusive older sister]], is a more obvious example, being a head cheerleader and the leader of a trio composed of her and her two friends.
* Rhonda Wellington Lloyd comes between this and RichBitch in some episodes of ''WesternAnimation/HeyArnold'' However, she actually ''is'' shown to have a friendly side, since her best friend Nadine actually ''is'' implied to be a middle-class girl (and with almost ''completely different interests'' than Rhonda--Nadine loves arthropods, Rhonda loves fashion). Her romantic interest in Harold, who actually is fat and less popular, is another redeeming feature.
* ''WesternAnimation/{{Horseland}}'':
** There are sisters Chloe and Zoey Stilton. They're definitely Alpha Bitches, and also RichBitch material compared to LonelyRichKid Sarah Whitney; in the first episode, everyone was initially afraid of Sarah because they worried she would be like the Stiltons. In "Bailey's New Friend", a new boy called Jesse arrives at the stable and is befriended by [[NiceGuy Bailey]], whose parents own the stable, and ends up forgetting Sarah, Molly, and Alma. Zoey and Chloe use the new friendship to try and break up the friendship between Bailey and the five main girls. They do this for no other purpose than to see how miserable the girls will be without their friend. He soon realizes he forgot them and reconciles with them in the climax.
** We also get the one-off character Talia Bentley in "Changing Spots", who is an even worse example who cares about nothing but riding and winning. She's basically what Zoey and Chloe would've been if they were not [[LovableAlphaBitch lovable.]]
* WesternAnimation/{{Jem}}
** Pizzazz. Full stop. It's also possible that, for all 80s animated female characters, she emerged as the ULTIMATE Alpha Bitch of that entire decade.
* Pretty from ''WesternAnimation/{{Kaeloo}}'', who is a {{rich| bitch}} {{spoiled brat}}. Most of her roles in the show involve her insulting or bullying everybody else, and even [[ExtremeDoormat her own sister]] isn't safe from her abuse. As a result of this, [[HatedByAll the rest of the cast (barring her sister) utterly despises her.]]
* Bonnie Rockwaller on ''WesternAnimation/KimPossible'', except she tries (repeatedly and in vain) to usurp the role of captain from the cheerleading heroine. Bonnie did eventually become cheerleading captain in one episode, and much to Kim's initial dismay, proves to be exceptionally competent and dedicated to the job (though she wasn't any less bitchy). Kim eventually decides to not fight it, as she's sure Bonnie will get [[WantingIsBetterThanHaving sick and tired of all the hard work involved with being squad captain]]. And she's right; the next episode showing the cheerleading squad, [[StatusQuoIsGod Kim's clearly back in charge]].
* ''WesternAnimation/LesSisters'':
** Rachel. She is very popular among her classmates and she is a rude and snobbish BitchInSheepsClothing who does horrible things such as locking Wendy and Marine out of their own house and throwing a party in it, or threatening to rip up a stuffed animal belonging to Marine, ''who is seven years old''. She especially targets Wendy because Wendy is more popular than she is and the guy she likes is Wendy's boyfriend.
** Rachel's mother also seems to be an adult version of the trope.
** Wendy is an aversion. Despite being the most popular girl at her school, she's friendly and kind to her family members and classmates most of the time.
* The Biskit twins from ''WesternAnimation/LittlestPetShop2012''. They don't appear to be the typical popular kids and are not outright hostile most of the time, but being rich, they are so pampered that as a result, they're distant from everyone else and are so used to getting what they want that they do ''not'' take kindly to Blythe declining their offer of friendship in the first episode. [[TookALevelInJerkass They become more openly antagonistic later on]] in season 2, but it gets dialed back when they get {{Morality Pet}}s in season 3.
* ''WesternAnimation/{{Lizzie}}'' has Brooklyn, whose sole purpose is to be the cool girl at school who treats Lizzie like garbage.
* Lori Loud, the eldest of the Loud children in ''WesternAnimation/TheLoudHouse'', is portrayed as a girly, boy-obsessed teenager who often tends to act mean not just toward her younger sisters, but also her only brother Lincoln. However, she still genuinely cares for the rest of her siblings.
* ''WesternAnimation/TheMightyB'''s Portia is the stuck-up, ValleyGirl, blonde Alpha Bitch, with front teeth that are even uglier than the main protagonist's. Her [[JewishAmericanPrincess cousin]] and mother are even worse.
* ''WesternAnimation/MiraculousLadybug'':
** Chloé Bourgeois. Her father is the Mayor of Paris and spoils his 'little angel' rotten. She hits all the marks for personality, but she is not very popular at all, with only one friend, Sabrina, [[WithFriendsLikeThese who she treats more like a servant]] and also doesn't understand what friendship might actually be. She thinks everyone adores her (they don't), and [[NeverMyFault can rarely accept she made a mistake]]. Among her most heinous acts is ''locking an emotionally insecure girl in the bathroom'' so she could be next to Adrien, who Chloé has a crush on (and said insecure girl does not) in a class photo. [[UnwittingInstigatorOfDoom She is responsible for most cases of people becoming sad or angry and getting brainwashed into supervillains]], to the point that Hawk Moth once created an akuma with no specific victim in mind and had it follow her around since he figured she was bound to piss ''someone'' off eventually. Unfortunately, he caught her on the day she was specifically trying to be nicer to people, so it took a little while, but she eventually delivered.
** Lila Rossi. She convinces the rest of the class, who adores her, to do whatever she wants and manipulates people to try and turn them against Marinette (the only person who doesn't like her). She also torments people for petty reasons, such as sending a picture of herself kissing Adrien to Kagami, or the aforementioned turning people against Marinette because Marinette refuses to believe her BlatantLies. She also acts spiteful and horribly rude, insulting people behind their backs.
** Audrey Bougeois is one of these all grown up -- she's a snobby, rude, and narcissistic [[CausticCritic fashion critic]] who belittles and threatens to fire anyone that doesn't meet her impossibly high standards. Her own family isn't exempt from this; her treatment of her husband is flat-out DomesticAbuse, she alternates between belittling her daughter while misremembering her name and encouraging her to follow her example (said daughter being [[GenerationXerox Chloé]]), and [[spoiler:while she treats Zoé slightly better, she doesn't really pay attention to her unless she puts up a JerkassFacade]].
%%* Angela, from ''WesternAnimation/MonaTheVampire''. She is shown to be snobby and mean.
%%* Patty Smirnov and Mattie O'Hare, the [[SchoolNewspaperNewshound school journalists]] in ''ComicBook/MonsterAllergy''.
* ''WesternAnimation/MonsterBusterClub'' gives us a subversion of the AlwaysFemale rule. Resident Alpha Brat Mark is a ''male'' Spoiled Blond Rich Kid who delights in insulting and generally being less than pleasant with the four [[KidHero kid heroes]], apparently for no reason.
* Cleo from ''Toys/MonsterHigh'' is popular, vain, and frequently tries to manipulate situations to be about her. However, she does love her boyfriend and her friends, and occasionally displays redeeming qualities, becoming more of a LovableAlphaBitch as time goes on. {{Deconstructed|Trope}} in that her popularity is the result of her need for positive attention, which comes from her father and older sister treating her coldly and telling her about the importance of power, both of which went to Cleo's head.
-->'''Cleo:''' "I'm Cleo De Nile, and I've got to give the people what they want."
* Tiff and Brit, the Crust cousins from ''WesternAnimation/MyLifeAsATeenageRobot'', who continually plot to keep Jenny/XJ-9 unpopular.
* Diamond Tiara from ''WesternAnimation/MyLittlePonyFriendshipIsMagic'', with Silver Spoon as the BetaBitch, are a pair of {{spoiled brat}}s who tease [[PluckyGirl Apple Bloom and Sweetie Belle]] about not developing cutie marks yet, and taunt Scootaloo about the fact that she can't fly. [[HeelFaceTurn The episode "Crusaders of the Lost Mark" reveals Diamond was raised to be mean by her mother Spoiled Rich, who's far worse than she is, prompting her to stand up to her near the end and become nice.]]
* ''WesternAnimation/NeoYokio'': Arcangelo is a male example. He leads the "east side gentlemen" who look down on Kaz for being NouveauRiche.
%%* ''WesternAnimation/TheOblongs'' has Debbie Klimer and her posse of identical Debbie clones.
* In ''WesternAnimation/PixelPinkie'', Suzi is the school's alpha bitch who immediately marks Nina as a target for her strange clothes and AmazinglyEmbarrassingParents.
* Amity Blight in ''WesternAnimation/TheOwlHouse'', although she is technically more of the [[AcademicAlphaBitch academic variety]] and grows into a [[LovableAlphaBitch lovable one]] fairly quickly. Her friend Boscha, while a BetaBitch in status, is a more straight example in regard to attitude. Following Amity [[TookALevelInKindness taking a level in kindness]] midway through Season 1, Boscha becomes the new Alpha Bitch in her place.
* Princess Morbucks on ''WesternAnimation/ThePowerpuffGirls1998''. She's a rich, spoiled Prima Donna that thinks she's better than the girls. Nobody at her school likes her. She even wants to become a member of the girls, which they turn down because she lacks any qualities of the team. Taken up notches in the [[WesternAnimation/ThePowerpuffGirls2016 2016 reboot]]; she no longer wants to be the fourth Powerpuff Girl, she wants to be the ''only'' Powerpuff Girl.
* ''WesternAnimation/PrincessNatasha'': Greg's girlfriend Kelly is this, at least as far as Natasha is concerned. She is totally self=absorbed and her 'crimes' include wearing too much makeup and cheating off her fellow students.
%%*Vendella [=DeVil=] from ''WesternAnimation/OneHundredAndOneDalmatiansTheSeries''.
* [[Film/{{Heathers}} The Ashleys]] in ''WesternAnimation/{{Recess}}''. Despite having some moments where they aren't a bunch of {{Rich Bitch}}es, they spend the majority of the series wanting to screw with everyone for the sake of being mean.
%%* Sierra [=McCool=] in Disney's ''WesternAnimation/TheReplacements''.
* Maimy from ''WesternAnimation/{{Robotomy}}''. One of the most popular girls at Harry S. Apocalypse High and just as violent and hot-tempered as every other robot. In one episode, she started dating main character Thrasher (who has a huge crush on her) after he became student body president, but only did so to become vice president and overthrow him.
* ''WesternAnimation/{{Rugrats}}'':
** Angelica became this in the transition from ''Rugrats'' to ''WesternAnimation/AllGrownUp'', though she's admittedly ''less'' of a jerk than she used to be, being a rather LovableAlphaBitch instead of an EnfanteTerrible. Maturity can do that to you sometimes...
** She's ''less'' of an Alpha Bitch compared to Savannah Shane, a girl whom even Angelica can't stand (and yet, she always seemed to be trying to get in her good graces). A particularly strong example comes from the episode when Savannah plans a party on the same day as Angelica's thirteenth birthday party, and it's found out that she did it on purpose to "teach Angelica a lesson" after sitting at her lunch table.
** In [[WesternAnimation/Rugrats2021 the reboot]], Charlotte Pickles, Angelica's mom, goes from a TheWorkaholic JerkWithAHeartOfGold to a stuck-up city councilwoman who snobbishly insults the other parents.
* Vana Glama from ''WesternAnimation/{{Sidekick}}'' is a classic case, a popular and self-centered primadonna who gets the best grades at the Sidekick Academy, has all the boys (especially Eric) drooling over her, and is served by the beleaguered nerd Kitty Ko.
* In ''WesternAnimation/TheSimpsons'' episode "Eight Misbehavin'", the family describe what happened to them during a nine-month mid-episode TimeSkip. Lisa reveals that she became the most popular girl in school, "but then blew it by being conceited". Whilst [[NoodleIncident/TheSimpsons the details of this are never revealed]], it is probable that she became an Alpha Bitch during that period.
* Gemini Stone from ''WesternAnimation/SabrinaTheAnimatedSeries'', a stand-in for the original Libby on the live-action series.
** Also Portia from the friends forever movie.
* ''WesternAnimation/TheSpectacularSpiderMan''
** [[AllGuysWantCheerleaders Liz]] was introduced as one, mocking Peter as much as everyone else, until a boost of CharacterDevelopment after seeing him in different light turned her into his love interest.
** Sally Avril is the most abusive girl of the group, even mercilessly mocking fellow clique-member Flash Thompson when his [[HeroWorshipper hero]], Spider-Man, appears to be committing robberies. Slightly subverted when Peter's aunt has a heart attack as Flash mentions that even Sally feels sorry for him, although she is not as forthcoming with her sympathies as his friends are. Both she and [[JerkJock Flash]] have gone through a bit of CharacterDevelopment. When she thinks that Peter's been killed, Sally is horrified. She does ''say'' it's because she'll have to tell Liz and Liz "looks awful in black", but when she sees that Peter's okay, she performs a textbook AngerBornOfWorry. A bit later, she tells him that no, she doesn't care, but she doesn't want him to be blown to bits, she's not a monster. In the last episode, she's glad Liz broke up with Peter[[note]]When in reality Peter breaks up with her because of his feelings for Gwen Stacy but publicly breaks Peter off to save face[[/note]].
* Gretel from ''WesternAnimation/StainesDownDrains'' is the arch-enemy of Mary-Jane. She is a spoilt girl who usually bullies the Staines with her friends, the Lupe brothers.
* Brittney Wong from ''WesternAnimation/StarVsTheForcesOfEvil'' hits all the typical beats: she's a [[SpoiledBrat bratty]], [[ItsAllAboutMe selfish]] RichBitch who became captain of the cheer-leading squad at Echo Creek Academy "on her own, and [[SuspiciouslySpecificDenial not because her dad made a generous donation to the school]]." Naturally, Brittney hates Star for being one of the few kids she can't intimidate and for stealing attention away from herself.
* ''WesternAnimation/StrawberryShortcake'':
** Angel Cake has moments of such in the 2003 series, especially in the final season, to the point of playing the villain in "Sleeping Beauty".
** Peppermint Fizz was this in her early appearances but outgrows such behavior following her redesign.
** Raspberry Tart/Torte becomes one in the [[WesternAnimation/StrawberryShortcakeBerryInTheBigCity 2021 series]], with the addition of AdaptationalVillainy. She [[CharacterDevelopment drops this]] after Season 1, when she [[DefrostingIceQueen warms up to Strawberry]] and [[HeelFaceTurn becomes]] [[TookALevelInKindness one of her closest friends]].
* Melody from ''WesternAnimation/TeenageFairytaleDropouts'' is a mean girl in that she's constantly looking down on Fury for the latter being a fairy who still hasn't grown her wings yet.
%%** The Grimm Sisters.
* ''WesternAnimation/TotalDrama'':
** From the first generation, [[Characters/TotalDramaHeather Heather]] and [[Characters/TotalDramaCourtney Courtney]]. Heather is a [[BitchAlert classic queen bee]] whereas Courtney revealed herself to be a BitchInSheepsClothing with her [[ControlFreak bossy]] and [[CompetitionFreak overly competitive]] personality as the series progressed. Both were the Alpha Bitch on their respective teams in the first two seasons with Heather serving as the show's main Alpha Bitch in ''Island'' and Courtney in ''Action''. However, in ''World Tour'', both girls clash for the position.
** From the third generation, [[LeanAndMean Amy]] and [[FatBitch Sugar]]. Amy treats her twin sister Samey with [[KickTheDog absolutely no respect]], and pretty much acts like a {{Jerkass}} towards her other teammates as well, particularly Jasmine. Sugar is a pageant brat who asserts herself as the dominant female, especially over Ella and Sky.
** From the fourth generation, [[Characters/TotalDramaJulia Julia]]. She starts as a fake GranolaGirl social media influencer, but BeneathTheMask, she's as self-absorbed as one can get. MK eventually exposes Julia's real personality to the world, but Julia's popularity doesn't suffer for long-- she gets thousands of new followers who enjoy her real personality, and she's relieved that she no longer has to act nice to be popular.
* ''WesternAnimation/TotalDramaPresentsTheRidonculousRace'':
** Taylor [[UngratefulBitch treats]] [[PushoverParents her mom]] Kelly like shit, and she is often rude to the other contestants.
** Josee is a rare adult version, given how she regularly bullies her partner Jacques and belittles other teams, primarily the Cadets and the Sisters.
* Mandy from ''WesternAnimation/TotallySpies'' is a textbook case of this trope. Extra points for being shallow. Her cousin Mindy is also shown to be this, but it takes five seasons for her to show up.
** It's [[SpinOff spin-off]] show ''WesternAnimation/TheAmazingSpiez'' also has this with Tami.
* Coral from ''WesternAnimation/{{Trollz}}'' is the head cheerleader, perpetually stuck-up, and is mean to the BFFL. She gets a case of BreakTheHaughty when Simon temporarily takes over and makes her his servant, and when Amethyst helps her she thanks the cast before returning to her usual ways.
%%* Sincerity from ''WesternAnimation/WhatAboutMimi''.
* ''WesternAnimation/WinxClub''
** A girl from Bloom's old hometown named Mitzi definitely fit the bill, despite appearing only a few times. In the Halloween episode, she invited Bloom and her friends to a party--which turned out to be an elaborate scheme to humiliate the girls. She bought and rigged a house, made up an elaborate legend, hired actors to pose as party guests (complete with scripts), and set up elaborate special effects around the house, just to pull a prank on someone she had barely seen in two years, along with four girls she had never met. Mitzi gets a more prominent role in some episodes of the fourth season: [[spoiler: she lays her eyes on Brandon and wants to take him from Stella]]. Later, [[spoiler:the Wizards of the Black Circle temporarily turn her and two friends into evil fairies.]] After that, she's practically PutOnABus. She appears again in Season 5, and whatever time she's not playing fangirl to the Trix involves her being a bitch to her [[BigBrotherBully little sister]].
** The Trix themselves qualify. They bully others in school and generally boss others around before getting expelled. After episode nine, they get much, much worse, what with the multiple attempted homicides, turning TheCutie into a pumpkin for ruining one of their plans, removing the heroine's powers in a needlessly sadistic way after threatening her parents and revealing her backstory, and attempting to take over the universe. They're like [[Film/MeanGirls Regina George]], only with magical powers.
%%* Victoria Best from ''WesternAnimation/WordGirl''.
* Christie Wilson from ''WesternAnimation/TheWeekenders''. She's a snooty jerk.
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