All women and girls are irritable while on their period.
Pre-menstrual syndrome (PMS) refers to the physical and mental effects of hormone changes in females of childbearing years. Those effects can include depression, tender breasts, food cravings, bloating, fatigue, mood swings, constipation or diarrhea, and irritability. The Mayo Clinic estimates that three out of four women between puberty and menopause will have some form of PMS. If a fictional work decides to avert No Periods Period, though, forget about the 25% who don't suffer any ill effects. The only effect of PMS will be irritability, and every menstruating woman will suffer from it. Occasionally, a work will use a different effect of PMS. However, even then authors stick to effects that make the character irritable. Cramps are good for this, especially considering that 2-3 days of pain will make just about anyone cranky. Bloating might show up so the character can complain about her clothes not fitting. You won't see food cravings, though, unless the character is about to learn she's pregnant.
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