Sometimes when sucking out the poison
isn't enough, someone simply cuts off the limb in question, above the problem. Naturally, this is not recommended in real life as blood flows faster than an arm or leg can be cut off, and amputation is dangerous enough as is. Though amputations to prevent infections are an old medical practice.
Subtrope of Life or Limb Decision
Anime and Manga
- Bleach anime episode #275. Barragan uses his Respira attack against Captain Soifon, causing her arm to disintegrate starting at the fingertips. She orders her lieutenant Omaeda to cut off her arm before the decay reaches her body, and he does so.
- In Naruto, Sasuke envelops himself in a wall of inextinguishable Amaterasu flames, but the Fourth Raikage attacks right through it with his left arm. To stop the fire from spreading through the rest of his body, he cuts it with his right arm.
- The Thing From Another World: Climate of Fear, a sequel series to The Thing (1982), Agapito cuts off his arm with a machete to keep himself from being infected.
- In Evolution, Dr Block finds himself host to an alien fly that is burrowing into his leg. He refuses to let doctors cut off the leg in question until he learns that it's headed for his testicles. Ultimately, they pull it out of his rectum instead.
- Averted in Creepshow, when Jordy opts not to go for medical help because he's afraid the doctor will amputate his "meteor shit"-infected fingers without anesthetic.
- In Norwegian zombie movie Dead Snow, one of the characters lops his own arm off after being bitten by a zombie on said arm.
- When Segen gets infected during the Jerusalem sequence in World War Z, Gerry cuts off the infected limb and applies first aid as quickly as he can.
- Subverted in the 1988 remake of The Blob. The homeless man suddenly shows up wielding an axe, but it turns out that he's trying to hack his lower arm off because the micro-blob that fell from space has started consuming it. Before he can finish, the blob clutches to the limb's remainder to continue eating him.
Live Action TV
- In The Clone, when a guy accidentally touches the eponymous creature (which immediately starts converting his still-living flesh into its own flesh), the protagonists try to stop it by applying iodine (which the Clone is repulsed by) to his arm. What they don't realize is that the Clone then works its way around iodine on the surface, to eat its way through the inside of the arm. When they discover that, they have no choice but to amputate the whole arm before it reaches the torso.
- In Remnants two of the characters have to have appendages amputated to remove worms that are slowly eating them. One of them is a redshirt, who bleeds out after his leg is removed. The other is a main character, who only loses a finger.
- Discussed in Curse of Chalion by Lois McMaster Bujold. The royse Bergon was wounded in the thigh by a leopard's claws, and the wound turned septic when he left it untreated, before it was discovered.
"His [Bergon's] rising hysteria [about the amputation] was only calmed when a second physician opined that the infection was not gangrene after all—Cazaril's nose agreed—but rather, blood poisoning, and that amputation would do more harm than good now."
- The Guns of Navarone. One of Major Franklin's legs is broken during the climb up the cliffs and gangrene later sets in. The team leaves him with the Germans and the leg is amputated to prevent the gangrene from spreading to the rest of his body and killing him.
- Tamora Pierce's Wolf-Speaker has the mage Gissa, who cuts her own hand off after it gets hit by a drop of the Bloodrain poison potion she was stirring. If she had left it long enough for it to reach her bloodstream it would have rotted her from the inside out; once it reached full strength they were planning on pouring it into the river, killing every living thing within ten miles.
- In an episode of Red Dwarf where Lister is infected with a sentient virus they try to isolate it in one arm and cut that arm off. Lister spends the next episode trying to cope with one arm, and when that fails get a new one.
- Doctor Who: In "The Seeds of Doom", after Winlett is infected by the Kyrnoid, the team plans to amputate his arm to stop the infection. However, the Kyrnoid takes him over and he escapes before they can do so.
- In The Walking Dead episode "Seed", they attempt this with Hershel after he is bitten. It works.
- The X-Files: Amputation is used as a preventative in a small Russian town near an industrial complex where the Purity (aka Black Oil) alien virus is being experimented with. They only want to use completely healthy individuals so if the locals cut off an arm it won't attach to them. They almost cut off Mulder's arm before he escapes, but Krycek isn't so lucky.
- In the series finale of Copper, which features Morehouse, Corcoran and Freeman out in the Southern wilderness hunting John Wilkes Boothe, Morehouse's prosthetic leg begins to chafe on his stump, and it eventually becomes infected. For a while, Morehouse attempts to simply ignore it, but after a while the pain from the infection is so great he can barely walk, remarking that his leg "hurts worse than the day [he] lost it." Freeman, a doctor, eventually has to remove the lower part of his stump to stop the gangrene from spreading.
- In The Walking Dead, after Lee is bitten he can try this to stop the infection. It doesn't work; even if you cut his arm off Lee will still die at the end of Episode 5.
- In Girl Genius Dimo gets stung on the arm by some glowing blob thing and Oggie rips the arm off. The non-Jaegers in the group think he's overreacting, until the severed limb melts.
- "Biscuit" in Goblins gets infected with a flesh-rotting curse after standing on a severed finger ripped off the body of an Eldritch Abomination. He opts to cut the infected leg off with an axe.
- In Ugly Americans a batboy gets loose in Mark's counseling group and bites Mark and the Two-Headed Worm Guy. After killing it Grimes draws a machete and slices off Worm Guy's bitten hand (which regenerates). Mark (who got bitten on the crotch) pretends that it didn't get him and slowly transforms over the rest of the episode, until it turns out that Doug the Koala Man's saliva acts as an antidote.
- This used to be the only method of stopping gangrene from spreading. Nowadays, the rotting area can often be saved, but amputation is still sometimes required.
- The Manhattan Project had a policy to cover contamination with plutonium. Anyone who had plutonium enter their body through a cut or a scratch on a limb would be subjected to immediate high amputation to keep it from entering the rest of their body. Robert A. Heinlein mentioned this policy in his short story "The Long Watch".