Stuff gets tested on humans all the time in real life. However, in Fictionland, there doesn't seem to be any body that protects the rights of test subjects. In real life, the Declaration of Nuremberg first established that first and foremost, human test subject must consent
to anything done to them. That would probably help avoid a lot of Phlebotinum Rebels
in Fictionland. The Declaration of Helsinki later established general principles established to protect the rights of human test subjects, most of which the Mad Scientist
never seems to give a fig about.