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9* ''Series/ThirteenReasonsWhy'': Tyler. From being an [[Sandbox/AmbiguousDisorder awkward, friendless]] photographer and revealed StalkerWithACrush (taking pictures outside Hannah's window), he's bullied and mistreated by [[KickTheDog virtually everyone]] despite his part in Hannah's TraumaCongaLine not being nearly as terrible as, say, Sheri [[spoiler:fleeing after knocking down a stop sign and refusing to call the police in fear of her future being ruined, which leads to [[LovableJock Jeff]]'s death]], Bryce [[spoiler:raping her, which breaks her soul]] or Mr. Porter, [[spoiler:who [[AdultsAreUseless tells her that unless she admits to who raped her, she needs to just "move on"]]]]. In season 2, while the other recipients of the tapes gradually come together in solidarity, Tyler continues his descent, becoming friends with a fellow outcast, with whom he goes out shooting guns and exposing the unfair treatment the popular, wealthy students receive. Unfortunately, by the end of the season, he's alone once more and his last action against the baseball team (which causes the season to be canceled) [[spoiler:is the catalyst for [[HateSink Montgomery]], a {{sociopath}}ic school bully and Tyler's most consistent tormentor, to [[DoubleStandardRapeMaleOnMale violently sodomize Tyler in the boys' bathroom with a broken broom handle]]. This is Tyler's DespairEventHorizon and drives him to follow up on a plan to commit a mass shooting at the Spring Fling dance. Clay talks down an armed Tyler, and proceeds to help cover up the attempt by dumping the weapons in the river.]] The character development in season 3 grows to subvert this trope.
10* ''Series/TwentyFour'':
11** Jack Bauer almost winds up becoming this. Throughout the entire series, he's been betrayed, used, exploited and almost all his friends and loved ones have wound up dead. In Season 8, his last potential love interest is killed and the President betrays him which proves to be the last straw, sending him on a RoaringRampageOfRevenge to expose the conspirators behind the day's events which in turn lead to his love interest dying and then mercilessly '''slaughter''' them, which turn out to be [[spoiler: former President Charles Logan and Russian President Yuri Suvarov]]. What sets him apart from most of the others is he does still have some rationality and does overall still refuse to harm any innocent life; when pressured into the fact that going down this path would lead to several casualties in the ensuing war between the United States and Russia, he realized what he was doing was in the wrong. He may have stopped himself after ''realizing'' what he was doing would kill more innocent than guilty, but prior to that he pulled some pretty risky moves, including opening fire on a crowd of civilians in order to get to said [[PresidentEvil corrupt President]] which could have backfired horribly and killed someone. I'd say he qualifies.
12** Depending on how you view him, Tony Almeida.
13* Tate Langdon from ''Series/AmericanHorrorStoryMurderHouse''. He's mentally damaged, neglected by his parents, and clearly depressed...and also a seemingly sweet boyfriend. And he cries so prettily! On the other hand, he's a [[spoiler:mass-murdering, stalking ghost]].
14* Holtz in ''Series/{{Angel}}''. He was a vampire hunter whose family was brutally murdered by Angelus and Darla to torture him. Except for his daughter, whom they turned into a vampire so Holtz would have to kill her himself. His guilt and rage caused him to [[RevengeBeforeReason abandon reason for vengeance]] and pursue Angel to the twenty-first century and manipulate people for his own ends.
15* ''Series/AshesOfLove'': On the one hand Run Yu plots against his father, steals his half-brother Xu Feng's throne, and eventually goes to war against Xu Feng. On the other, his mother's murdered in front of him, his fiancée cheats on him with Xu Feng, his father has him arrested at his wedding... and all of that on top of the literal ''millennia'' of abuse he's already suffered. It's a miracle he didn't snap much sooner.
16* ''Series/BoardwalkEmpire'':
17** Richard Harrow is an expert killer, utterly broken by his experiences and injuries in the trenches of the First World War. His only friend, Jimmy, is a gangster who has a use for Harrow's skills. Harrow has therefore murdered a couple of dozen people on screen, many of them without even asking why.
18%%** Also, Jimmy is revealed to be one in Season 2.
19* ''Series/BreakingBad'':
20** Walter White could be interpreted as this. He is an extremely intelligent and skilled man, but works as a high school chemistry teacher and has to watch his former classmates and business partners from [=Caltech=] become multimillionaires off the company he co-founded. After a lifetime of this kind of indignity, without ever fighting back, he gets diagnosed with lung cancer; this humiliation collectively pushes him over the edge into cooking meth so he can make back the money he lost and get even with a world that continually screwed him over.
21** [[AntiVillain Jesse Pinkman]] is one, himself. Oh, you can taunt him all day, everyday: for years. And, he'll just take it. With, perhaps, the odd, nasty prank in retaliation, but nothing more. The minute you press his {{Berserk Button}}s of 1) harming people he cares about, 2) [[FriendToAllChildren harming children]] and/or 3) harming or threatening to harm children he cares about as the utter worst, however... you will find out that all that taunting? Has created an unstable, dirty nuclear device with [[ChaoticStupid a dodgy timer]]. [[HonorBeforeReason Which you have just primed]]. He [[UnstoppableRage won't care about the consequences]]: [[RoaringRampageOfRevenge he'll take you down as soon as he is able to get a solid fix on your position and has a clean line of sight.]] And, the fallout won't be pretty or discriminate, however low-yield he appears in comparison to others on this list.
22* ''Series/BuffyTheVampireSlayer'':
23** Willow, in the Season 6 finale. Her RoaringRampageOfRevenge over [[spoiler:the death of Tara]] ended with a magical overload that briefly attuned her to the thoughts and feelings of everyone else on the planet. Overwhelmed by the world's collective pain, she decided that [[PutThemAllOutOfMyMisery "your suffering has to end"]] and turned her newfound power towards bringing about TheEndOfTheWorldAsWeKnowIt. She was finally stopped by ThePowerOfLove.
24** When Faith is responsible for accidentally killing someone, Buffy and the rest of the gang offer to help her with her issues, only for things to go south when [[UnwittingInstigatorofDoom Wesley]] [[InterruptedCooldownHug has her shipped off to indefinite imprisonment]]. The result? She no longer trusts them, and becomes TheDragon to the BigBad.
25** Drusilla, (after what Angelus [[BreakTheCutie puts]] [[BeingTorturedMakesYouEvil her through]]) [[WaifProphet so]] [[TheWoobie very]] [[FemmeFatale very]] [[TheOphelia much]].
26** Warren was on the receiving end of a ''lot'' of bullying growing up, mentioning how he used to cry himself to sleep.
27** One-off villain Ford from "Lie to Me." An old friend of Buffy's, he makes a deal with Spike to let him feed on a bunch of {{Vampire Vannabe}}s in exchange for becoming a vampire himself. When Buffy confronts him, it turns out that [[SecretlyDying he has brain cancer]] and only has a few months left to live.
28* ''Series/ColdCase'' tends to feature lots of {{Tragic Monster}}s and {{sympathetic murderer}}s, but a particularly [[AxCrazy gruesome]] example is the Serial killer in ''it takes a village''. Surely someone who [[WouldHurtAChild tortures, mutilates and murders young boys]] just because they are able to [[WorthyOpponent beat him]] at a ''video game'' couldn't possibly have any sympathetic qualities right? As it turns out [[spoiler:the game is symbolic of a room in a particularly awful foster home where he spent his childhood]]. During which he and five other boys were made to stand naked on a square ''for days at a time'' by his counselor. He attempts to stand up to said counselor. [[SurprisinglyRealisticOutcome Instead of joining in, the other boys gang up on him]] [[{{Fingore}} and cut his finger off]]. He targeted boys who reminded him of the ones who attacked him and at times seems to legitimately believe its ''them'', even though its been over twenty years. By the time the detectives catch up to him, he's an [[TalkativeLoon incoherent mess]] who slips in and out of {{third person|Person}}. He finally comes to his senses long enough [[spoiler:to realize that his latest intended prey is just an innocent little boy who has nothing to do with what happened to him so he lets him go.]] As awful as his crimes were, even the detectives couldn't help but feel a tinge of [[SympathyForTheDevil sympathy]] for him, or at least for the little boy he was.
29* Many unsubs from ''Series/CriminalMinds'' and its spin-off, ''[[Series/CriminalMindsSuspectBehavior Suspect Behavior]]'':
30** Veronica Day, who manipulated her boyfriends into killing their parents because [[spoiler:someone killed her birth mother before she had a chance to tell her who she was, and if she couldn't have a happy family, then ''no one could''. And on top of that, she was caught because everyone thought she killed her mother. She was freed on a technicality but redeemed herself by confessing to one of her victims]].
31** A mother who goes on a shooting rampage on her child's birthday/death day, who has a special grudge against "heroes" because not only was her child's injury and death ignored due to a police officer being killed in the same incident (they were caught up in a car chase), her own husband was a workaholic paramedic who didn't even take time off for his own son's birthday, eventually divorced her, and seemed too quick to get over his son's death (he hadn't, he just didn't show it as much as she did).
32** A father whose son was a SerialKiller, and blamed his [[InTheBlood "rotten genes"]] for what happened, kills any young man who happens to have the same glasses as his son, but shifts targets to the father of one of the victims who has been harassing him for years eventually, hoping for a SuicideByCop. He also attempts to MercyKill his very ill wife, but is unsuccessful.
33** Another father who, after the death of his wife, planned to murder-suicide himself and his three sons by ''sneaking pipe bombs into their backpacks and sending them off to school, a field trip, and the hospital where their mom died''.
34** A young woman who, as a teenager, was repeatedly raped and beaten by her father ''and'' brother, and when her doctors finally managed to convince her to go to the police with it, she found her mother already at the station denying everything. She snapped and began believing that all women should suffer what she did (and, presumably, what she wanted to do to her mother), recruiting her weak-willed, toadyish husband to do the actual raping part.
35** A woman who abducts other women, injects them with a paralyzing drug that will eventually kill them, and plays with them like dolls...because she walked in on her pedophilic, psychiatrist father giving away her favorite toys (given to her to keep her quiet while he was abusing her) to his latest patient/victim.
36** A comic book artist ForcedToWatch as his pregnant fiancée was ''raped to death in front of him'' by a street gang. The trauma causes him to have episodes where he blacks out...during which time he, without knowing it, becomes a ''crazy'' skilled VigilanteMan, butchering members of the gang with katanas.
37* ''Series/{{Dexter}}'' has the Trinity Killer. Notable in that this trope is used to make the character more disturbing, rather than more human (the usual utilization of this trope). Also [[VillainProtagonist Dexter Morgan]], himself.
38* ''Series/DoctorWho'':
39** The poor, confused robot deliberately driven insane by a fringe political group in [[Recap/DoctorWhoS12E1Robot "Robot"]] is a clear example. It's forced to kill people, murders its own father, has a FreakOut, decides humanity is fundamentally corrupt, and then attempts to cause a nuclear holocaust to kill everyone on Earth apart from Sarah Jane as she was the only person who ever treated it with basic respect.
40** [[AntiVillain Omega]], poor poor, screwed up, insane [[AlasPoorVillain Omega...]]
41** In [[Recap/DoctorWhoS27E6Dalek "Dalek"]], the eponymous creature, despite killing many people throughout the episode and wishing to wipe out all life on Earth, suffers several existential crises in a row, from being (it believes) the [[LastOfHisKind Last Of Its Kind]] to being part human thanks to the method of its healing. Ultimately, it is DrivenToSuicide over the pain of emotions it never even knew existed.
42** An in-universe example from [[Recap/DoctorWhoS27E10TheDoctorDances "The Doctor Dances"]]:
43--->'''The Doctor:''' All that weapons tech in the hands of a hysterical 4-year-old looking for his mummy.... There isn't a little boy born who wouldn't tear the world apart to save his mummy -- and this little boy can.
44** [[Recap/DoctorWhoS28E1NewEarth "New Earth"]]: The infected clones, after they escape, spread their diseases to anyone they touch, but they're only doing it because they're desperate to be touched, and want someone to help them and love them.
45** [[Recap/DoctorWhoS30E17E18TheEndOfTime "The End of Time"]]: characterises the Master this way -- outrageously evil and destructive, but due to the Time Lords intentionally tampering with his brain when he was a child, leaving him permanently tormented by hallucinations of war drums.
46** River Song, a LaserGuidedTykebomb who attempted to destroy the fabric of time itself attempting to avert the inevitable death of the Doctor. Fortunately, the Doctor saw her potential, having known the [[StableTimeLoop good person she'd become after this event]], and married her.
47** The War Doctor seems to be this, being responsible for destroying Gallifrey. [[spoiler:Or is he?]]
48** The Twelfth Doctor temporarily becomes this in the final three episodes of Series 9 when NoGoodDeedGoesUnpunished results in a TraumaCongaLine. In [[Recap/DoctorWhoS35E10FaceTheRaven "Face the Raven"]], Clara stops him from going on a rampage when [[spoiler:she -- his MoralityChain! -- '''must''' die when her efforts to stop a plot go horribly awry]], but it's clear that he can only keep his anger and anguish in check for so long. Next in [[Recap/DoctorWhoS35E11HeavenSent "Heaven Sent"]], he is trapped in a torture chamber [[spoiler:and spends ''billions of years'' '''''and lives''''' escaping. The culprits were '''his own people''']]. He emerges at the DespairEventHorizon and hot for {{Revenge}} and succor in [[Recap/DoctorWhoS35E12HellBent "Hell Bent"]]. It turns out he underwent most of the torture to [[spoiler:get the means to save Clara from her fixed-point-in-time death]], and in pursuit of this TragicDream risks the entire universe's safety, heedless of the wishes and entreaties of others -- all because '''''he can't take it anymore!''''' [[spoiler:When he tries to mind wipe her to keep her safe, she tinkers with the device. Upon being told this, and uncertain whether the tinkering had any effect, Clara and Doctor agree to push the button together and let fate decide; ultimately, ''he'' loses most of his memories of ''her'']], but he accepts this fate as a proper punishment, having already realized/admitted the wrongness of his actions at last, and allows things -- and himself -- to return to their proper state. This is in many respects an uber-example of the trope because far from being a potential "Destroyer of Worlds", for a brief period the Doctor is actually headed to become Woobie, Destroyer of ''Time''.
49** [[Recap/DoctorWhoS37E9ItTakesYouAway "It Takes You Away"]]: The Solitract, a [[GeniusLoci sentient universe]] who causes the plot because it's lonely and [[IJustWantToHaveFriends wants friends]]. It's lonely because it causes the fundamental laws of our universe to fail, which is why it had to be exiled for the universe to exist, so it has to exist away from the universe in complete solitude.
50* In ''Series/{{Fringe}}'', [[spoiler:Walternate. His son was kidnapped. His world is in the process of tearing itself to pieces, and millions of his fellow human beings have been killed. He's also waging a shadow war on our universe, since he thinks that it's the only way his can survive]]. Interestingly, in the alternate reality where Peter died as a boy ([[spoiler:an Observer did not save him]]), Walternate is better than Peter initially assumes him to be.
51* By the penultimate episode of ''Series/GameOfThrones'', [[spoiler:Daenerys Targaryen has lost two of her dragons, most of her friends (one of whom is executed in front of her), and any semblance of support in Westeros; the North wants nothing to do with her, half of the people who know she's not the rightful Targaryen heir apparent spurn her off, while the others are alienated by the reckless actions she took on the way to the Iron Throne. Her march to Westeros is in tatters, and the only sane option would be to return to Essos, defeated but retaining her dignity. But sane she is not; Daenerys realizes that this means she has lost so much to achieve precisely ''nothing'', so there must be another option that will make her suffering less bitter. It turns out there's one: her last remaining dragon, named after her late husband, who once made a promise to bring the Seven Kingdoms to its knees. So she... fulfills the promise by torching the entire King's Landing with dragonfire, killing one of her two rivals to the Iron Throne, [[JumpingOffTheSlipperySlope as well as tens of thousands of innocent civilians]].]]
52* Adam Monroe on ''Series/{{Heroes}}'' his path of destruction fueled by his heartbreak over Yaeko.
53** Surprisingly, [[BigBad uber-villain]] Sylar (a.k.a. Gabriel Gray). When Peter visits a [[AlternateTimeline potential future]], Sylar [[UnstoppableRage accidentally destroys Costa Verde]] after the [[DespairEventHorizon death]] of [[spoiler:[[MoralityPet his son]]]]. He was also that in the regular timeline from his terrible childhood.
54* The Greeed from ''Series/KamenRiderOOO'' are monsters whose MO is consuming the world and are generally causing massive pain to everyone. Then we find out why they're doing it. Their 10th Core Medal was destroyed, leaving them sentient, but even if they get all 9 of their remaining Cores, they have a void inside them that can never be filled due to the destruction of the 10th. They've been that way since they've become sentient, they're only trying to consume the world to fill a void inside them that they were born with. If that hunger is enough to drive them to the extremes they go to, then they definitely qualify.
55* The [[GrandFinale final]] perp on ''Series/LawAndOrderCriminalIntent'' turns out to be [[spoiler:a woman who runs an internet company (a sweeter, female Mark Zuckerberg {{Expy}}) who, tipped off to a break-in at her headquarters, returns to confront the offending party and finds that he has killed her boyfriend. He runs at her and she retaliates with a scissors to the neck. She]] actually breaks down into TenderTears when confronted with the evidence, and it is clearly intended that our sympathy should be with [[spoiler:her]].
56* ''Series/LawAndOrderSpecialVictimsUnit'':
57** One suspect, who suffered from a terribly-painful terminal health condition, started a website on which she advised other people on how to commit suicide. Her willingness to facilitate suicide even in the clinically-depressed made her morally culpable in several preventable deaths.
58** Another suspect, while not [[spoiler: the episodes main killer]] he has killed for as little a crime of ''taking his photo'' and has attempted to kill others and his cult of [[TheSchizophreniaConspiracy conspiracy theorists]] even [[spoiler: indirectly caused the main victim’s death]] and probably other untold tragedies. Suffice to say it’s easy to hate him… until you remember that he’s a severely schizophrenic man due to losing his parents in a plane crash as a child causing him to believe that the whole world was "out to get him". That’s enough to make anyone sympathetic!
59* In ''Series/LegendOfTheSeeker'', Nicci is even more of this trope than in the books, as her KnightTemplar tendencies are downplayed and more emphasis is put on her desire to destroy the world.
60* Morgana from ''Series/{{Merlin|2008}}''. She has magic, in a place were that is a death sentence. Aims to stop this but no one will help her. Is turned on by her former friends, as they ignore her and keep things she really should have been told. Merlin is the worst in this.
61* ''Series/OnceUponATime'':
62** Regina, a.k.a. The Evil Queen is a powerful sorceress who has murdered several innocent people, has an [[RevengeBeforeReason irrational grudge against Snow White]], and wipes the memories of everyone in her ''world'' because of that grudge. [[spoiler:But she was also [[FreudianExcuse raised by a heartless queen]] who murdered the [[InterClassRomance servant boy]] she was in love with after a young Snow was manipulated into revealing their relationship.]] Also, the adoptive son she genuinely loves is disgusted with her past and (at least at the beginning of the series) wants nothing to do with her. She tries to reform, but [[BeingGoodSucks things always seem to get worse for her when she does]]. And it helps that actress Creator/LanaParrilla is an absolute ''master'' of making kicked-puppy-dog faces.
63** Mr. Gold, a.k.a. Rumpelstiltskin, started out as a normal person. Then he crushed his lower leg so that he would be send home from the Ogre Wars, after being given a (self-fulfilling) prophecy regarding his then unborn son growing up fatherless, just as he did himself. His wife, along with the rest of the village, declare him a coward. She spends years abusing him, finally leaving him and their son, Baelfire, for [[spoiler: Captain Hook]]. When Bae is 'drafted' (the Duke's men come into the village and steal children away to place on the battlefield) as canon fodder in the the same war at the age of 14, Rumpelstiltskin looks for a way to save him and is tricked into becoming The Dark One. The curse overcomes him and he first takes revenge on his abusers, then saves the surviving children from the battlefield. His son finds a way to go to a land without magic, believing this will save his father from the Dark One curse. Rumpelstiltskin, having experience with portals ([[spoiler: his father abandoned him via a portal when he was a small boy]]) of the type that Bae creates, is too frightened to go through. He regrets it immediately, and spends the next 300-plus years searching for a way to reunite with his son. He eventually helps and falls for a young [[spoiler: Cora]], and she [[spoiler: rips out her own heart to avoid feeling anything for him in return]] so that she can marry a prince to make herself royalty, and to obtain power and revenge on those she believes wronged her. Years later, he falls in love with [[spoiler: Belle]], who [[spoiler: attempts True Love's Kiss on him with no warning after being tricked into it by Regina, Cora's daughter. He kicks Belle out of the castle, and Regina kidnaps her, keeping her imprisoned while telling Rumpel that his True Love was DrivenToSuicide]]. While in the Land Without Magic, finally having found a way to locate his son, Captain Hook [[spoiler: shoots Belle in the back, driving her over the cursed town line and into Rumpel's arms, making her lose her memory of him]]. Later, Rumpelstiltskin sacrifices his life to [[spoiler: keep his father from murdering Belle and Baelfire, and turning the town into HellOnEarth]]. He is later brought back to life, only to end up in the clutches of [[spoiler: Zelena, the Wicked Witch of the West]], in an attempt to save his son's life. He's kept as a prisoner and slave for a year, tortured physically and psychologically. His son [[spoiler: ultimately dies to save the town, and Rumpel is forced to watch, then forced to watch Zelena brag about Baelfire's death, and kept from even attending the funeral]]. Later, oozing PTSD, he's overtaken by the Dark One curse and does some very bad things to [[spoiler: try and remove himself from the influence of the dagger that controls his soul while under the curse]]. He's caught at it and is banished from the town by [[spoiler: Belle]], during the six weeks of which he finds that [[spoiler: his heart is being consumed by the Dark One curse and unless he finds a cure, the human part of him will die and the curse will be free to use his body to do what is wishes without his consciousness and lingering goodness to hold it back]].
64** Jefferson, aka the Mad Hatter. He's pushed into what he does by Regina's manipulation and betrayal, plus love of his daughter. Also, he's been driven more than a bit crazy by his time in Wonderland and being one of the few conscious people in Storybrooke.
65** As a boy, Greg Mendell and his father ended up camping in the woods when the Dark Curse created Storybrooke. This let them enter the town where the mayor (Regina) decided to make him her adoptive son, whether he likes it or not. Greg escaped from Storybrooke but his father sacrificed himself to do it. Greg spent the rest of his life trying to find Storybrooke, and his father, again and every action he takes is to this end.
66** Ingrid, the Snow Queen spent most of her life fearing her powers over ice. One day [[spoiler: she accidentally killed one of her sisters with her powers and her other sister imprisoned her in a magic urn, thinking she was a monster.]] This twisted her thinking so that she believes only those who have magic could love her and everyone else deserved to die.
67** Maleficent spends most of Season 4B trying to get revenge on Snow White and Prince Charming. Why? [[spoiler: Their actions caused Maleficent to lose her baby daughter without ever seeing her face or knowing what happened to her.]]
68** ''Poor, poor Drizella.'' [[spoiler: Her own ''mother'', Rapunzel Tremaine, was willing to [[OffingTheOffspring kill her]] and use her heart to revive her sister Anastasia, the latter of whom she [[ParentalFavoritism does care about.]] She also has no friends in Seattle, with the exception of Henry and formely Gothel. Ironically, Drizella ended up being a ''Creator of Worlds'', seeing as how she created Hyperion Heights through the new curse. Come "Secret Garden", and her mother [[HeroicSacrifice sacrifices]] herself to save her.]]
69** Tremaine is also this to an extent, [[spoiler: seeing as how her actions were caused by her husband Marcus and Drizella essentially [[ReplacementGoldfish replacing]] her with the latter' stepmother Cecelia when she was locked in a tower, along with Anastasia's death]].
70** The second half of Season 7 introduces two more ones: [[spoiler:Jack/Nick and Gothel]].
71* ''Series/OrphanBlack'': Helena. A clone, separated from her birth mother [[spoiler:and from her twin sister Sarah]], raised in a convent [[spoiler:before being abducted and turned into a TykeBomb by a religious psycho]] which led her to start performing large ritual scarifications on her back, was forced to [[spoiler:murder her fellow clones one-by-one]], and when she finally found the strength to [[RageAgainstTheMentor rebel]], she was taken by [[spoiler:another bunch of religious nutjobs who forced her to get married and performed invasive procedures to steal her egg cells in a very rape-y scene]], before one of them flat-out tried to [[VorpalPillow murder her]]. Oh, and that [[spoiler:twin sister]] she feels a connection to ? She impaled her on one occasion, and shoot her at point-blank range on another. The one and only character that ever showed any kindness to her was [[spoiler:[[MoralityPet Kira]], Sarah's daughter]].
72* The adaptation of Creator/AgathaChristie's ''Elephants Can Remember'' by ITV's ''Series/{{Poirot}}'' features a CanonForeigner, [[spoiler:the daughter of the mentally unhinged killer from the original story, who is embittered and broken by what happened to her mother and takes murderous revenge]].
73* Dr. K in ''Series/PowerRangersRPM''. She unleashed a sentient computer virus that almost certainly nuked the planet, and is confirmed to have wiped out all of civilization outside of one city. Her motive? Escape from the top-secret government think-tank she had been trapped in all her life. In her defense, the guards caught her before she could set up a firewall. So she ''[[MikeNelsonDestroyerOfWorlds unintentionally]]'' killed most of humanity in an attempt to escape unjust imprisonment. And since the firewall was intended to keep the virus from escaping from the computer network in the first place, some consider it [[UnwittingInstigatorOfDoom the indirect fault of the guards who kept her from installing it, thus guaranteeing spread of the virus]].
74** When Tenaya 7 invades her lab, [[TheReasonYouSuckSpeech she mocks her]], saying, "You pride yourself on how smart you are, don't you? But you still [[NiceJobBreakingItHero royally messed up]], didn't you?" -- after which the usually cool Dr. K completely loses it and angrily starts firing her sound cannon in random directions. After the flashback ends, she appears emotionally exhausted, most likely because of the guilt she faced for her mistakes, thus cementing her status on this page.
75* ''Series/PrincessAgents'':
76** Yan Xun. All of his villainous actions are to get revenge for his murdered family.
77** Yuan Chun. All of her villainous actions are to get revenge for being raped.
78* ''Series/{{Smallville}}'' have a very large number of villains, and while many earlier ones are AxCrazy Psychopaths, middle and later seasons have introduced a lot of {{Tragic Monster}}s and these.
79** "Hidden": Gabriel Duncan's father spent a long time trying to convince people of the mutating effect of [[GreenRocks kryptonite]] but failed and ended up being a meteor freak himself, and asked his son to kill him. Feeling that the plague of the meteor infection will grow out of hand after the second, larger meteor shower, he decides to nuke the entire town. Not before warning, and when she attempts to talk him out of it, kidnapping [[VillainousCrush Chloe]], though.
80** In Season 8, [[spoiler:they managed to make Doomsday to be something like this because of the horrible life Davis, his human host, has had.]] He was abandoned as a kid as opposed to having loving MuggleFosterParents like Clark, and is cursed to bring nothing but death and destruction.
81* ''Series/StarTrekTheNextGeneration'': Kevin Uxbridge, from the Season 3 episode "The Survivors", was a powerful god being called a Douwd. He took human form and married a woman named Rishon and put aside his powers. Kevin also became a pacifist and took an oath to never kill another being. Moving to a Federation colony on Rana IV, the colony was attacked by aliens called the Husnock. Kevin tried to use illusions to drive the Husnock away, but after they killed his wife, Kevin destroyed all the Husnock, 50 billion of them, in a moment of rage and grief. Horrified at his actions, Kevin went into self-imposed exile on Rana IV, recreating his house and his wife on the ruined planet. When the Enterprise comes to investigate a distress call sent by the colony, Kevin tries to use illusions to drive them away. When Picard confronts Kevin for all this, Kevin breaks down and admits his crime, his actions still tormenting him.
82* ''Series/StargateSG1'':
83** Played with in "Absolute Power" with Daniel Jackson, the show's typical [[TheWoobie Woobie]] of various other types. [[spoiler:In the episode, Daniel is trying to sensitively obtain information about the Goa'uld from a small child, who touches his head in an apparently hostile act, as it renders him unconscious. When he awakens, he proceeds to have all of the needed knowledge revealed to him and proceeds to build the weapon that would apparently defend the Earth, but at the cost of having become at least a JerkassWoobie if not outright evil. He fantasizes about very violent things until, finally, his goal is met. He then proceeds to take over the most powerful weapon in the world from his SupervillainLair and destroy Moscow before waking up and realizing that having absolute power to defeat the Goa'uld in one fell swoop is not such a good idea after all. He wakes up to discover that it was AllJustADream, but during]] the episode, it was implied that this trope actually simply a part of his subconscious, with or without special knowledge. Not surprising, really.
84** [[RidiculouslyHumanRobots The scared, lonely robot girl]] who created the Replicators.
85* ''Series/{{Supernatural}}'':
86** [[spoiler:Castiel in the sixth season finale]]. Abandoned by God, at war with his brothers, rejected by both allies and his TrueCompanions for [[IDidWhatIHadToDo doing what he has to do]], and hopped up on the souls of millions of monsters and {{Eldritch Abomination}}s from Purgatory, he declared AGodAmI and demanded that everyone bow down and worship him, or else he would destroy them. It did not end up well.
87** As of the Season 9 finale, [[spoiler:Dean]]. His entire life has been devoted to saving others, to his own detriment more often than not, with no credit, or appreciation from anyone but his fellow hunters (even his own family constantly abandons him and yet expects him to clean up their messes), he finds out he was genetically engineered by Heaven itself, was raised as a warrior TykeBomb with little love shown him by his borderline insane father and now, after literally allowing himself to be murdered to keep from becoming a monster he's [[spoiler:the First Knight of Hell, the Demon that all other demons fear, more powerful than the King of Hell and only less powerful than Lucifer himself]] and all because he wanted to save the world and keep the angels and demons from having their gang war on his planet.
88** Demons in general qualify as this once you find out their backstory: they're destructive, sadistic monsters purely because they [[spoiler:are humans who have undergone such horrific torture in Hell for so long that they literally lose their memories of everything except Hell and subsequently lose their humanity, turning just as depraved and warped as their torturers. How did they get to Hell in the first place? Maybe they made the unfortunate decision to sell their soul to a stranger at the crossroads for a wish. Or maybe the angels running Heaven decide they needed to be punished for something, barred them from Heaven, and sent them to Hell after they die. (By the way, crimes that warrant this range from getting tricked into doing something wrong to refusing to follow their screwed-up orders.) Or even just because the King of Hell has reapers on the payroll and can get ANYONE he wants condemned to Hell]]. '''''Jeez.'''''.
89* The ''Franchise/UltraSeries'' have numerous examples, where the MonsterOfTheWeek is either a victim of circumstance, an experimental test subject GoneHorriblyWrong, or an innocent, misunderstood creature without any malicious intent, being forced into going on a rampage.
90** Kupukupu from ''Series/ReturnOfUltraman'' starts off as a rabbit-like space critter captured in a cage, right in the middle of the show where kaiju attacks are in full-swing. Harbouring fears towards extraterrestrial organisms, the humans decide to have the harmless creature executed via disintegration, only for a random chunk of Kupukupu to grow and adapt into a much more powerful and dangerous kaiju form, Kingstron, which then understandably goes on a rampage.
91** Ron was originally the pet lizard of ''Series/UltramanLeo'', who barely escaped Planet L-77's destruction. Separated from it's master and adrift in space for months without food and water, it lose it's harmless, dormant lizard form and transforms into a kaiju, which then crashes on Earth going on a rampage.
92** ''Series/UltramanEighty'' has the creature, Myu, a harmless creature the size of a puppy, who was stolen from UGM's labs by an unscrupulous scientist, hoping to convert Myu into a bioweapon of sorts, subjecting Myu to ForceFeeding and ElectricTorture in order to enforce loyalty from Myu. This ends up backfiring when Myu, after being injected with a serum, ends up growing to kaiju-sized and attacking the city.
93*** A later episode from the same show has Gauss, a harmless alien animal whose entire planet was wiped out by a nuclear missile test from the humans, oblivious of the planet having innocent life on board. The nuclear missile mutates the monkey-sized Gauss into kaiju form as it then crashes on Earth, intending to destroy all humans as retaliation.
94** Kei Fukuide from ''Series/UltramanGeed'', an alien from a planet destroyed in a cataclysmic war, whose absolute despair he experienced stems from him having no purpose or future until the series' BigBad, Belial granted it to him. His final moments alive are spent pathetically pleading with a nonpresent Belial to tell him he was useful.
95* ''Series/{{The Umbrella Academy|2019}}'' has the example of [[spoiler: Vanya. Belittled and abused by her father, ignored by her siblings, left out of everything, constantly reminded that she is ordinary and useless by everyone. Her sole confidante, Five, disappears. Her brother Ben dies. She gets nowhere with her violin playing and remains stuck at third chair for years. And then Leonard (or rather Harold) starts manipulating her, and she discovers her immense powers. And ends up nearly killing her sister, killing Leonard when she discovers his lies, collapsing her family's house (after being locked in a small, soundproof room by her brother), killing Pogo and their mother, flipping a car after the driver shouts at her, and ending the world via a burst of energy that destroys the moon]].
96* ''Series/VeronicaMars'': [[spoiler:Cassidy Casablancas]] was molested by his little league coach, belittled and picked on by his father and brother, and abandoned by his mother. It causes him to go crazy and blow up a BusFullOfInnocents.
97* ''Series/{{Warehouse 13}}'' had a textbook example in [[spoiler:H.G. Wells. It started out with her daughter being murdered, who proceeded to hunt the killers down and cause them more pain than she felt. Then, after being turned into a statue for a century ([[FateWorseThanDeath while still awake the whole time]]), she found today's world [[HumansAreBastards even more lacking]], and decided to explode the Yellowstone supervolcano to start an ice age. In a twist similar to the ''Series/{{Buffy|TheVampireSlayer}}'' example above, HoYay saved the day]].
98* The entire premise of ''Series/{{WandaVision}}'' is based on [[Characters/{{Scarlet Witch}} Wanda Maximoff]] being so [[SanitySlippage mentally broken]] after seeing her love interest, Vision, '''[[Film/AvengersInfinityWar killed twice]]''' that she [[spoiler:'''unknowingly''' enslaved the population of an entire New Jersey town to create a fictional sitcom world in which Vision was still alive and they had children. When she realized that this world was her doing, she was fearful of ending it because she thought her magic was making everyone's lives ''better'' - because nobody was able to break character and inform her that she was mentally torturing them all this time]]. [[ExaggeratedTrope Even worse,]] [[spoiler:if she tried to end the spell prematurely without coming to the stage of acceptance, Vision and her children would be brutally and excruciatingly ripped apart by the lack of magic allowing them to maintain physical form. After accepting what she must do and letting the Hex dissipate, causing her family to peacefully vanish, she indirectly states that she deserves NoSympathy despite what she had to give up and punishes herself by going into exile in order to repent for what she did to Westview - [[OhCrap except she takes the corrupting tome known as the Darkhold with her]] because she ''has to'' in order to learn how to control her powers if she is ever to interact with anyone ever again]].
99* ''Series/WordOfHonor'': The Scorpion King is an assassin who'll do literally anything for Zhao Jing, but he also desperately wants Zhao Jing's love and is heartbroken when he finally realises Zhao Jing is only using him.
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