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1A subcategory of Webcomics involving {{science fiction}}-based plotlines. Pretty much anything that makes regular, plot-intensive use of objects which are scientifically fantastic qualifies here.
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3We know that [[Analysis/SpeculativeFiction drawing the line]] between these and [[FantasyWebcomics fantasy]] can get a bit [[ScienceFantasy confusing]], so just use your best judgement. However, if it's a modern-day setting with only a few sci-fi elements for humorous effect, then it's probably [[EmbellishedWebcomics Embellished]] rather than sci-fi.
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6''Feel free to add comics to the list in '''alphabetical order'''. All links should be Administrivia/{{WikiWord}}s, even if we don't have a page for the comic yet, or you'll break the [[Administrivia/HowIndexingWorks new indexing system]]. If a page is added for a work, please remove the external link.''
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8[[index]]
9* ''Webcomic/TwentyFirstCenturyFox'': A romantic comedy set in 2066, dealing with the building of a prototype SpaceElevator. All the characters are IntelligentGerbil versions of various animal species.
10* ''Webcomic/AbstractGender''
11* ''Webcomic/AchillesShieldmaidens'': A HumongousMecha comic by Creator/StjepanSejic set in the early 24th century.
12* ''Webcomic/TheAccidentalSpaceSpy''
13* ''Webcomic/AcrossTheEras''
14* ''Webcomic/TheAcryden'' (Original website seems to be lost; there's an [[https://tapas.io/series/The-Acryden incomplete archive]] on Tapas, and according to the creator's Twitter she's "Working on a new website for the comic and trying to find the right path forward that works"): An {{Animesque}} sci-fi fantasy about demons, aliens, love and intergalactic treasure hunting. The Acryden, a dangerous magical item, has once again come into existence. When the Acryden's powers are accidentally unleashed, the ancient magic proves more powerful than anyone could have imagined, and the destinies of those involved are about to change forever! (Excerpt from [[http://new.belfrycomics.net/ent/19728 Belfry listing]].)
15* ''Webcomic/AddictiveScience'': The adventures of mad scientists.
16* ''Webcomic/TheAdventuresOfCaptainStarshield:'' A short prequel comic set within the ''Franchise/RatchetAndClank'' universe made to tie into the then upcoming game in the series, ''VideoGame/RatchetDeadlocked''.
17* ''Webcomic/TheAdventuresOfJoeTheCircle''
18* ''Webcomic/TheAdventuresOfKaniraBaxter'' [[http://kanirabaxter.comicgenesis.com/]]: A CGI comic set in the far future and following the eponymous Kanira Baxter, [[ExactlyWhatItSaysOnTheTin who has adventures]].
19* ''Webcomic/TheAdventuresOfSuperheroGirl''
20* ''Webcomic/TheAdventuresOfTerrikZion'': An undetectable alien invasion force has arrived from the furthest reaches of space, intent on devouring every world in the Tiras Star Cluster. Terrik and his crew find themselves in a one-sided war against an implacable enemy.
21* ''Webcomic/AfterlifeBlues'': A petty criminal is blackmailed into serving as a guide to his home planet, New Abilene. But rescuing an ArtificialIntelligence from a technologically fearful planet may not be so simple.
22* ''Webcomic/AfterTheDream'': What if the government's experiments with mind control didn't stop with MK-ULTRA?
23* ''Webcomic/AimForTheStars'': Doomed to grow up and die on a colony spaceship in the middle of nowhere, 14-year-old girl Kate is trying to fulfill her lifelong dream of becoming a space pilot, and explore the Universe.
24* ''Webcomic/{{Alcatury}}'' [[http://alcaturybok2.smackjeeves.com/]]: An out of this world story. With intelligent fish, faeries and "high" elves.
25* ''Webcomic/{{Alethia}}'' [[http://alethia.kstipetic.com/]]: Robots on a distant world try to find meaning in their lives after being abandoned by their creators.
26* ''Webcomic/AliceGrove'': The titular individual lives in a small forest town and held in almost mythical regard by the locals for her ability to resolve any problem. Then a feckless blue-skinned tourist almost literally falls out of the sky...
27* ''Webcomic/{{Alienated}} ''[[https://www.webtoons.com/en/challenge/alienated/list?title_no=325778]]: Ali's just your average shut in, she likes to stay home, eat junk food, watch horror movies, and avoid interacting with the rest of the populous ''(sic)''. Oh, and she's also an alien.
28* ''Webcomic/AlienDice'': Described in the article as a deconstruction of the {{Mon}} genre, where unfortunate HumanAliens have to play a DeadlyGame of GottaCatchEmAll. Its mood ranges from lighthearted to (despite the strange premise) pretty depressing.
29* ''Webcomic/AllenTheAlien'': A man gets abducted, and his wife tries to write a novel.
30* ''Webcomic/AlmightyProtectors'': Eight superheroes have adventures across various universes.
31* ''Webcomic/AlphaShade'': War/espionage story spanning both Earth and the titular parallel world.
32* ''Webcomic/{{Alter}}'' ([[http://pinali.net/alter/]]): A RealRobotGenre sci-fi story set TwentyMinutesInTheFuture spanning Earth and a {{crapsack|World}} AlternateUniverse. (The webpage is unfortunately down.)
33* ''Webcomic/AlwaysHuman'': Two women in a future filled with nanotech body modifications and other wonders fall in love.
34* ''Webcomic/TheAmazingPlasmaMan'' [[http://www.amazingplasmaman.com]]: A superhero comic revolving around the eponymous Plasma-Man, but also including a cast of his [[{{Supervillain}} enemies]] and [[{{Superhero}} allies]].
35* ''Webcomic/AmericanBarbarian'': action and adventure in a comic-book setting, purporting to be futuristic America.
36* ''Webcomic/AmongTheChosen'': Baphomet and Psychic Lad, vs [[CoolOldGuy an ex-GRU Comman. der]], who [[GottaCatchEmAll fight for control over]] the unaware [[BlessedWithSuck avatars]] of gods.
37* ''Webcomic/AndItDontStop'': In a semi-futuristic world where rappers and their robots compete in Tech-Hop tournaments, a newbie with the alias of "Ice Cream Man" and his partner Crush Groove strive to be the best.
38* ''Webcomic/Angels2200'': A gritty SpaceOpera with an [[ImprobablyFemaleCast all girl cast]] and plenty of QueerRomance.
39* ''Webcomic/AnnaGalactic''
40* ''Webcomic/AntiheroForHire'', a comic by the same author as ''{{Webcomic/Adventurers}}!'' It's set in a [[CyberPunk stereotypical grim future]] with {{Super Hero}}es, involving all the tropes one might expect. And usually [[SubvertedTrope dancing up and down on their graves, laughing]].
41* ''Webcomic/{{Apothecia}}'': An eleven-year-old girl finds an intergalactic mass murderer in the woods behind her house.
42* ''Webcomic/AptitudeTest''
43* ''Webcomic/{{Aquapunk}}'': A soft sci-fi with fantasy elements as well. An action and political drama with heavy doses of mysticism, [[AnimatedArmor stone robots]], and FishPeople aliens. And yes, the whole story revolves around the [[OceanPunk underwater setting]].
44* ''Webcomic/AquaRegia'': It's a {{Cyberpunk}} webcomic, about a mercenary and his odd jobs.
45* ''Webcomic/{{Area42}}'': A paranormal investigator and an alien solve mysteries and watch stuff.
46* ''Webcomic/ArthurKingOfTimeAndSpace'': Multiple AlternateUniverse versions of Myth/KingArthur, including the original legend, [[JustForFun/RecycledINSPACE IN SPACE!]] and in the modern day.
47* ''Webcomic/{{Artifice}}'': An android soldier fails to kill his target and attacks the team sent to retrieve him. Now he must answer to his corporate masters—and they are not happy.
48* ''Webcomic/TheArtificeFliesAgain!'': Two delivery girls try their best to run a transport service and survive being hunted by the past.
49* ''Webcomic/ArtifiSouls'': An amnesiac robot tries to remember who he was in an alien planet.
50* ''Webcomic/TheArtistAndTheMachine'': Magical girl befriends robot sent to kill her. Fun, heroics and a black pug are to be expected.
51* ''Webcomic/AssemblyLine''
52* ''Webcomic/AsteroidQuest''
53** ''Webcomic/UnnaturalSelection''
54* ''Webcomic/AstoundingSpaceThrills'' [[https://steveconley.com/astounding-space-thrills/]]
55* ''Webcomic/{{Astray3}}'': Emily hides in a closet and finds herself stuck in another world.
56* ''Webcomic/ATaleOfFiction'': A story of unhumans' struggles against the discriminating, domineering DUF, using magique and unhuman abilities, and also of two guys who just happen to wander into the battle. Has a serious story arc, but . also keeps up a lot of humour, sometimes unintentionally when the German authors lose their grasp on their English.
57* ''Webcomic/AthenaWheatley'' or; ''Warp and Weft'': a story of a timetraveller from the past and a physicist from the future who's lives are somehow linked and who's universes are apparently being destroyed in closely related ways...
58* ''Webcomic/AttackOfTheSuperWizards'': There's a threat so big even an InvincibleHero can't handle it, so he peers out across TheAgesOfSuperheroComics to field a team of himself from across history.
59* ''Webcomic/AvasDemon'': Set about 1000 years in the future and features a young girl (Ava) who shares a body with a Demon. Said Demon possesses Ava at the worst possible times in order to cause her grief. Features robot armies (The Scavengers) and spaceships, while blending in fantasy elements. Also notable for its beautiful artwork and backgrounds.
60* ''Webcomic/AwfulHospital'': Set in a multiverse full of entirely alien logic and countless possibilities divided into separate "zones," and everything is part of a "concept core," where anything and everything can branch off of. Also, almost all beings see, percieve and experience things much differently than others.
61* ''Webcomic/{{Ayuri}}''
62* ''Webcomic/BabyAliens''
63* ''Webcomic/{{Backtrace}}'': A part of the Webcomic/PantsSeatCarpetRide web serial, which takes place in universe where interstellar travel is common. It is its own independent installment of the Pants Seat Carpet Ride serial.
64* ''Webcomic/{{BaDoom}}'' [[https://www.webtoons.com/en/challenge/badoom/list?title_no=302822]]: The bizarre adventures of a young woman and her talking dog as they make their way in post-apocalyptic America.
65* ''Webcomic/{{Banished}}'': A snarky alien and friendly robot embark on an unexpected adventures.
66* ''Webcomic/BattleKreaturez'': A story focused on the lives of professional monster-tamers.
67* ''Webcomic/BeardyBastards'': TheRemnant of a Squat hold devastated by a Tyranid splinter embark on a quest to bring a warning to any survivors.
68* ''Webcomic/{{Bearmageddon}}'': A MadScientist's mutated bears run amok, and a [[TheSlacker slacker]] named Joel is caught in the middle.
69* ''Webcomic/BecomingHero'': A comic book character discovers his author's responsible for all his mortal suffering -- and goes out to take revenge.
70* ''Webcomic/{{Beeserker}}'': Two scientists create a robot powered entirely by bees.
71* ''Webcomic/BicycleBoy'': A cyborg with amnesia searches for answers in the post-apocalyptic wasteland.
72* ''Webcomic/BinaryStars'': The daughter of an interstellar businesswoman is kidnapped by the literal man of her dreams, who turns out to be a bounty hunter and recognizes her from his past.
73* ''Webcomic/BioApocalypse'': A graphic novel drawn and written by a kid in sixth grade, scanned and uploaded to a ''Website/SomethingAwful'' forum many years afterwards, about the conflict between science and religion after Earth is engulfed by an EldritchAbomination.
74* ''Webcomic/BlacktailAndMarz'': An Earthling and her alien companion travel through space and time, getting into zany adventures.
75* ''Webcomic/BladeKitten''
76* ''Webcomic/BladeOfToshubi'': The story of a rogue {{Ninja}} mouse named Toshubi, set on [[AfterTheEnd a future Earth no longer populated by humans]].
77* ''Webcomic/BloodSplatteredSocks'': A boy who looks like a girl and a girl who looks like a boy become friends. Except one of them is a time traveller.
78* ''Webcomic/BlueYonder''
79* ''Webcomic/BooksDontWorkHere'': The story of a webcomic actress and the challenges she has to face. You know imaginary scripts, unreliable narrators, plot holes, meta walls, wacky physics, mad science, and convincing people to pay her for any of it.
80* ''Webcomic/BornSexyTomorrow'': A mercenary has to take care of a sexy cyborg designed to destroy mankind.
81* ''Webcomic/BreakpointCity'': A boy and his dog travel to the future.
82* ''Webcomic/BrokenSpace'' [[http://brokenspacecomic.com/]]: A SteamPunk[=/=]{{Magitek}} story set in an alien dimension, alternately funny and dramatic. Revolves around a doctor putting his life back together after a revolution on his homeworld, an assassin severed from her former employers, and a mad magician-scientist with plans for immortality.
83* ''Webcomic/ABrokenWinter'': Takes place on a distant world with no sun where humanity is divided into two countries. The story follows Kokkan, a brutally traumatized child, who is raised by a soldier, Kuoda, after his father is framed and branded as a traitor.
84* ''Webcomic/BrotherhoodOfTheBlackFlag''
85* ''Webcomic/{{Builder}}''
86* ''Webcomic/BuyingTime''
87* ''Webcomic/CaptainUfo'': Adventure/comedy series that follows the adventures of the titular Captain, aspiring galactic tyrant.
88* ''Webcomic/CarpeChaos'': An independent science-fiction space-opera webcomic about five alien races who learn to travel between stars. It focuses on the ways their cultures collide and how they work to solve their problems.
89* ''Webcomic/CaseyAndAndy'': The story of a pair of {{Mad Scientist}}s and their wacky hijinx as they deal with their girlfriends, try to TakeOverTheWorld and kill each other. [[RunningGag Repeatedly]].
90* ''Webcomic/CassiopeiaQuinn''
91* ''Webcomic/{{Cesium}}'': A group of physics grad students talking science, going about their day, and travelling through time.
92* ''Webcomic/ChaosTheory'': A group of teenagers fight off an army of aliens.
93* ''Webcomic/Chester5000XYV'': A tale about a Victorian housewife and the [[SteamPunk robot]] who loves her. Standard story, but told in a different format.
94* ''Webcomic/ChromaKey'': A diverse group of childhood friends reunite once an alien summons them to be a superhero team against a new alien threat.
95* ''Webcomic/CiemWebcomicSeries'': A series of [[VideoGame/TheSims Sims]] {{Machinomics}} chronicling the life and times of a college-age [[BioPunk mutant superheroine]] as she tries to balance her sacred calling to fight off genocidal aliens, government conspiracies, and other forms of evil; with her more mundane ambitions to start a family. Told in the [[http://www.comixpedia.org/index.php?title=DSHW DVD-Storybook Hybrid Webcomic format]], which is loosely inspired by The Sims Story Exchange. ''Ciem'' is being used primarily as a way to push for the acceptance of the DSHW format by the webcomics mainstream.
96* ''Webcomic/CityOfCards''[[http://www.cityofcards.com/]]: An amnesiac man tries to make a new life for himself in a dystopian future version of Reno, NV.
97* ''Webcomic/CityOfDepression'': A Teenager is responsible for the safety of humanity when a group of alien geneticists, who believe they have created two perfect human beings, call upon their superiors and initiate a galaxy wide test that erases all competing species who fail.
98* ''Webcomic/CircaAfterTheApocalypse'' takes place after an undetermined time period after Earth is bombarded by meteors, which devastate the world and raise a dust cloud that blots out the sun- the dust cloud seems to have settled prior to the events of the comic itself.
99* ''Webcomic/ClaudeAndMonet'': The year is 2318. A galaxy at war, mankind stretched to the limits of civilization. The militaries of humanity fight for mankind's very survival against an alien race. Meanwhile, undeterred, pirates, criminals, terrorists and corruption run rampant in allied space, preying on the weak and the innocent. Law enforcement agencies are unable to stem the tide... if they even bother. Private militias, bounty hunters and others try to fill the gap, but they are not always effective and sometimes make it worse. Some even become the evil they fight against. But sometimes there are individuals -- so-called "Professionals" -- who get the job done... for the right price.
100* ''Webcomic/CloserToHome'' [[https://closertohomecomic.com/]]: AfterTheEnd, [[ButWhatAboutTheAstronauts what happened to the astronauts?]]
101* ''Webcomic/CodeCrimson'': An ongoing sci-fi comic blending adorable art with brutal violence, complicated characters, alien espionage, and a massive conspiracy stretching across space and time. It's what would happen if ''Franchise/ThePowerpuffGirls'', ''Series/DoctorWho'', and Creator/QuentinTarantino had a threesome.
102* ''Webcomic/CogaNito'' Set in the modern day [well, 2006]. A guy is sent a link by an old acquaintance, which draws him into a series of battles revolving around [[EldritchLocation a pocket dimension that can only be accessed via the internet]].
103* ''Webcomic/ComboRangers'': A Brazilian ''Franchise/SuperSentai'' AffectionateParody, which was a straight-up parody before it started balancing out the comical and heroic aspects of its storylines, which may elicit a wide range of reactions.
104* ''Webcomic/CommanderKitty'': A weekly webcomic featuring the misadventures of a cast of {{Funny Animal}}s in space.
105* ''Webcomic/{{Concerned}}'': The Half-Life and Death of Gordon Frohman, a ''VideoGame/HalfLife2'' webcomic with a plot constructed almost entirely of [[LampshadeHanging lampshading]] and [[SubvertedTrope subverting]] VideogameTropes. Finished.
106* ''Webcomic/{{Contrasts}}'': A ''Franchise/StarWars'' fan comic in which Barriss Offee and Ahsoka Tano have mutual attraction toward each other. They fall in love during the Clone Wars.
107* ''Webcomic/{{Cooties}}'' [[http://cooties.spiderforest.com/]]: is an all-ages comic strip which follows a bunch of kids and their adventures dealing with school, friends, parents, the opposite sex, and the occasional paranormal/extraterrestrial catastrophe.
108* ''Webcomic/CosmicDash'': An adventure series following an alien crew during a galactic {{Cold War}}.
109* ''Webcomic/CosmicHero'': A guy finds an space suit, and must join an intergalactic army. (It's on a undefined hiatus)
110* ''Webcomic/CosmicScoundrels'': A comic about two intergalactic scoundrels on the run from everyone.
111* ''Webcomic/{{Cosmoknights}}'': A mechanic and a pair of spacefaring knights seek to upend the [[FeudalFuture patriarchal monarchy.]] [[RecycledInSpace In space.]]
112* ''Webcomic/TheContinentals'': A webcomic set in post UsefulNotes/{{JackTheRipper}} England where Continental Operative Jeffrey Tiffen Smythe and his gender bending partner the adventress Lady Fiona Fiziwigg investigating a series of brutal "mangling" murders uncovers a tangled web of intrigue, adventure--and murder!
113* ''Webcomic/CountdownToCountdown'': A post-apocalyptic sci-fi webcomic.
114* ''Webcomic/{{Crankrats}}'': A {{Steampunk}} webcomic.
115* ''Webcomic/{{Crash and Burn}}'': A webcomic about a deadly succession struggle among an alien race.
116* ''Webcomic/CrimsonDark'': This very good webcomic uses a unique art style, involving rotoscoping 3D scenes, and is heavily inspired by ''Series/{{Firefly}}''.
117* ''[[Webcomic/CrimsonStars Crimson Stars: Chains of Command]]'': A Vampire Space Opera.
118* ''Webcomic/TheCrossoverlord'': A superhero {{crossover}} webcomic.
119** ''Webcomic/{{Crossoverkill}}''
120* ''Webcomic/{{CrystalSun}}'': Aliens struggle with a mangled prophecy and what may or may not be their doom (or new beginning).
121* ''Webcomic/CuraTeIpsum'': Excellent [[TheMultiverse multiverse]] based comic concerning the adventures of the various incarnations of Charlie Everett as they try to kill themselves and each other. ItMakesSenseInContext.
122* ''Webcomic/{{Curvy}}'': A bunch of oversexed young folk travel among various alternate Earths, each with an [[VideogameSettings obvious theme]].
123* ''Webcomic/CwynhildsLoom'': A [[SuperSoldier cybernetically-enhanced former soldier]] lives on the run after refusing to have her tech deactivated and soon stumbles upon a plot that threatens all of humankind. Takes place on a terraformed Mars.
124* ''Webcomic/TheCyantianChronicles'': A ScienceFiction SoapOpera featuring [[UsefulNotes/FurryFandom furries]] as technologically advanced aliens. The Chronicles are composed of a handful of different webcomic series at different times and places in the continuity; the most prominent of these are ''Akaelae'' and ''Campus Safari''.
125* ''Webcomic/TheDailyDalek'': Humorous webcomic about the nemesis of ''Series/DoctorWho'' leading ordinary lives.
126* ''Webcomic/DangerZoneOne'': A cyberpunk buddy cop series starring two female officers busting crime all across the corrupt Pallad City. Filled with humor, action, detailed world building, and fanservice.
127* ''Webcomic/DareSensei'': A ''Series/DoctorWho''-based comic by Marybell and Toyloli with a distinctly Japanese approach.
128* ''Webcomic/DarthsAndDroids'': A new strip from the makers of ''Webcomic/IrregularWebcomic'', which translates the ''Franchise/StarWars'' saga into a TabletopRPG gone amok (using screenshots from the films).
129* ''Webcomic/DAndDS9'': Inspired by Webcomic/DarthsAndDroids, same concept but applies it to ''Series/StarTrekDeepSpaceNine''.
130* ''[[Webcomic/DansVoyage Dan's Voyage]] [[http://www.future-bound-entertainment.com/dans-voyage/comic/]]'': Sci-fi adventure following the crew of the space truck Charon IV as they explore the weird wonders of space.
131* ''Webcomic/{{Datachasers}}'': Datachasers is set in the distant future, in a world still recovering from an apocalypse. In it, humans and androids live side-by-side and face the hazards of their dangerous environment.
132* ''Webcomic/DawnOfTime'': The adventures of a prehistorical girl living 100 million years in the past. [[spoiler:Time travel is involved and there is an ancient civilization.]] Completed (for now...?).
133* ''Webcomic/DaxComics'': The story follows an intergalactic rapscallion of a mercenary known as Dax who finds himself saddled with a young girl. Hijinks ensue!
134* ''Webcomic/DecryptingRita''
135* ''Webcomic/DeepDiveDaredevils'': Follow the adventures of the eponymous crew of the USS ''Custer''. Set in TheThirties, but features a {{Cyborg}} submarine captain, Lost Technology and FrickinLaserBeams. And we're just getting warmed up...
136* ''Webcomic/{{Delia}}'' [[http://delia.thecomicseries.com/]]: Furry science fiction, set in a world of squirrel-folk that otherwise resembles 1950s America. When Delia accidentally makes contact with alien beings, she inadvertently triggers a chain of events that threatens her entire world. Now completed.
137* ''Webcomic/{{Demon}}'': A man who cannot die vs. a government agency trying to capture him.
138* ''Webcomic/TheDemonArchives'': Set in 22nd century Earth, over 100 years after the 3rd World War, the Demon Archives tells the survivors' stories as they struggle to rebuild civilization.
139* ''Webcomic/DenmaTheQuanx'': A Korean SpaceOpera Webtoon. An epic galaxy-spanning adventure with over 1000 pages (still being translated)
140* ''Webcomic/{{Derelict}}'': A scavenger lives on her boat in a post-apocalyptic world.
141* ''WebComic/DevilsDust''
142* ''Webcomic/{{Dicebox}}'' : Set InSpace and in the future, but most definitely not a SpaceOpera, this low-key SliceOfLife saga concerns a married couple (both female) aimlessly traveling from world to world. The {{Metaplot}} concerns the MysteriousPast of one of the two principal characters. Beautifully rendered and novelistic.
143* ''Webcomic/{{Dissonance}}'': Two scientists discover a peculiar animal, and try to determine what sort of creature it is. May or may not be a fantasy story in disguise, with a realistic portrayal of scientific research as applied to something that makes no scientific sense.
144* ''Webcomic/{{Distillum}}'': Two men save a young woman from getting killed, which disrupts the natural flow of time itself.
145* ''Webcomic/DivisMorte'': An alien planet gets invaded by merciless conquerors from other world. [[spoiler:Those merciless conquerors are humans.]]
146* ''Webcomic/DJGray''
147* ''Webcomic/DNATheWebcomic'': A story about some people who shouldn't exist, but do, and how they deal with that.
148* ''Webcomic/DomainTnemrot'': Gladiators wear special bands to become super powered as they fight to the death.
149* ''Webcomic/DressedForSuccess'': Alex Corbett and Walter Andrewkowski, two guys thrown together by chance, now making their way in a crazy universe one adventure at a time. All the while trying to stay one step ahead of the mafia and with the hopes of turning a profit.
150* ''Webcomic/DresdenCodak'': Kick-ass art, kick-ass philoso-nerdic themes. Be prepared to consult Wiki/TheOtherWiki for [[MindScrew references]].
151* ''Webcomic/DriveDaveKellett'': The story of a resurgent 25th-century [[UsefulNotes/{{Spain}} Spanish]] [[TheEmpire Empire]] founded on monopolistic control of ImportedAlienPhlebotinum -- the eponymous [[FTLTravel Faster-Than-Light drive]]. A small [[IdentityAmnesia amnesiac]] alien and the [[RagTagBunchOfMisfits rag-tag]] [[TrueCompanions crew]] that adopt him may hold the key to saving Earth in a brewing interstellar conflict...
152* ''Webcomic/DrNonami'': A [[ScienceHero young female scientist]] battles her [[MadScientist evil arch-nemesis]] for the fate of the world in this lighthearted adventure.
153* ''Webcomic/DrugsAndWires'': A pissy VR junkie and his ethically challenged cyberware installer face life's daily challenges in the dark future of 1995.
154* ''Platform/DummComics''
155** ''Earthward Ho!'': A comic about an alien obsessed boy who gets his wish and is abducted from his home. But a accident sends the ship he's on hurtling into the far reaches of space. Now he and his alien pal need to find a way to get back to Earth.
156** ''Mech Lab'': A comic about a the three robots of a science lab and the scientist who observes him...for the most part anyway.
157* ''Webcomic/Earth2068''
158* ''Webcomic/TheEasyBreather'': A smart blonde, a man who glows in the dark and a female dwarf campaign for truth, justice and clean air.
159* ''Webcomic/{{EATATAU}}'': A [[JediTruth Not-warhammer40k]] based webcomic following an AxeCrazy Kroott, two deeply depraved Ttau, and a not-Spacemarine as they face a galaxy where [[EverythingTryingToKillYou Everything Is Trying To Kill Everything Else]]. Recruited by a novice Eldar farseer and her Wraith Spider bodyguard to bring a warning of a (tyra)Nid splinter fleet to their (Space)craftworld. HilarityEnsues.
160* ''Webcomic/EDepthAngel'' [[http://mayshing.com/edepth/vol1/vol1.php]]: Set in the future, a young techno-nurse tries to save the humanity of [[WhatMeasureIsANonhuman cyborgs]] everywhere, including that of her client, the cold-hearted LienLei. Done in manga style, with great art and great mecha, and is one of the few in the mecha genre that appeals to both genders.
161* ''Webcomic/ElectricWonderland'': Website/PlatypusComix presents [[{{Cyberspace}} the Internet of the future]], seen from an IntrepidReporter and/or her six allies.
162* ''Webcomic/ElfBlood'': Science Fantasy, in which two factions of magical creatures wage a war of ideology. One unfortunate girl stands trapped in between, desperate to unearth her hidden heritage.
163* ''Webcomic/EllieOnPlanetX'': The reports of an adorable robot who makes first contact with a bunch of adorable aliens.
164* ''Webcomic/EmmyTheRobot'': A RobotMaid is adopted by a family and learns about the world.
165* ''Webcomic/{{TheEnd|2010}}'': A pair of aliens on a mission to relocate a population of humans to save them from destruction encounter a disaster of their own, leaving them stranded in space with a handful of humans picked up at a FanConvention.
166* ''Webcomic/TheEnds'': A story of survival and revelation in a post-apocalyptic wasteland apparently caught in a GroundhogDayLoop of death and rebirth.
167* ''Webcomic/{{Endtown}}'': A story that contrasts its funny animals setting with its apocalypse setting.
168* ''Webcomic/EnemyQuest''
169* ''Webcomic/EraOfErrors'': A story that takes place in modern California about a recent high school graduate whose best friend's dad has just made an extraterrestrial discovery.
170* ''Webcomic/EscapeFromTerra'': A story of the anarcho-capitalist asteroid Ceres and earth's attempts to bring them under its control.
171* ''Webcomic/EurekaSevenParadoxMakers'': A makeshift part 3 to the [[Anime/EurekaSeven original series]], DarkerAndEdgier with a female lead and a male love interest, all tied up in a battle about to go beyond the stars.
172* ''Webcomic/EverydayHeroes'': The story of PunchClockHero [[StevenUlyssesPerhero Mr. Mighty]] and his family's everyday life.
173* ''Webcomic/EvilPlan'': Evil Plan is a colored manga styled comic that takes the superhero world and flips it, viewing things from the supervillain's perspective. The story follows [[VillainProtagonist Dr. Kinesis']] journey on the road to world conquest.
174* ''Webcomic/{{Evus}}'': In a WorldInTheSky where [[{{Steampunk}} steampunk-esque]] technology is powered by crystal shards, land masses begin to fall from their positions in the sky. Wester and Maisy set out to save their town, but little do they know their adventure will quickly become far different and far greater than they could have ever imagined.
175* ''Webcomic/{{Exposure}}'': The plot is about two super hot girls Lisa and Shawna, who investigate and fight monsters and other otherworldly creatures.
176* ''Webcomic/FallCityBlues'': Follows the lives of Lex and Lucy, alternate reality versions of the same person who live together.
177* ''Webcomic/FalloutExiles'': A Fallout fan webcomic following a vault dweller named Bright's adventures throughout the Mojave and Texas.
178* ''Webcomic/{{FAMIB}}'': A 2001-ongoing webcomic in an AlternateUniverse.
179* ''Webcomic/{{Familiar Territory}}'': A cyberpunk action/drama webcomic about a bio-mechanic with severe wanderlust living in the quarantined city of Southland.
180* ''Webcomic/{{Far from Home|Kruslar}}'': A human boy awakens in a metal pod just as it plummets to the surface of an alien planet. Conscripted into forced labor for a race of decadent beings, he finds himself the newest member of a very unusual work team.
181* ''Webcomic/{{Far from Home|MightyMartianStudios}}'': A human boy travels with his parents in space, and the ShowWithinAShow of two heroes of the Space Patrol.
182* ''Webcomic/FarOut'': TheWildWest WITH ROBOTS!!!
183* ''Webcomic/FarOutThere'': To quote the tagline, it's "The webcomic where things happen... IN SPACE!"
184* ''Webcomic/FeastForAKing'': A sci-fi epic spanning several thousand years, multiple planets, several alien species, and strong erotic / horror / action elements told in AnachronicOrder.
185* ''Webcomic/TheFightingStranger'' [[http://www.drunkduck.com/The_Fighting_Stranger/]]: Set AfterTheEnd. A man wakes up without memory outside city populated by humans and robots.
186* ''Webcomic/FlightOfTheBinturong'': A weekly space adventure comic about a crew of space mechanics aboard the deep-space tow rig The Binturong.
187* ''Webcomic/{{Follower}}'': A comic that follows the staff of a secret military base and the [[HalfHumanHybrid half human hybrids]] they created. Prequel to Webcomic/{{Messenger}}.
188* ''Webcomic/{{Forming}}''
189* ''Webcomic/{{Fortuna}}'': A space adventure about video games and robots, but mostly robots.
190* ''Webcomic/{{Forward}}''
191* ''Webcomic/FoundationThePsychohistorians''
192* ''Webcomic/FreakAngels'': Creator/WarrenEllis' (''ComicBook/{{Planetary}}'', ''ComicBook/{{Nextwave}}'', ''ComicBook/{{Transmetropolitan}}'', ''ComicBook/TheAuthority'') stab at an online comic. Eleven psionic 23-year-olds try to hold civilization together AfterTheEnd in the flooded London borough of Whitechapel. Once described by the author as, "What if the children from ''Village of the Damned'' grew up to become disaffected twenty-somethings?"
193* ''Webcomic/FromEarthInPeace'': The people of earth have cured aging (a bit too well, making everyone children physically, but not mentally), then invented Ftl travel. Then they met aliens who think they're adorable.
194* ''Webcomic/{{Freefall}}'': The main characters include various sentient robots, a larcenous squid in an environment suit, a mad veterinarian (okay, not ''really'') and an engineer who's a genetically engineered wolf (and [[OnlySaneMan the sanest person in the strip]]). Contains a [[MediaNotes/MohsScaleOfSciFiHardness surprisingly high amount of real science]].
195* ''Webcomic/{{Furr}}'': A series about three [[Literature/WarriorCats warrior cats]], a wolf pup, a genre-savvy [[IntelligentGerbil alien vixen]], and their odd adventures.
196* ''Webcomic/{{GAAK}}'' [[http://www.webcomicsnation.com/moniquem/gaak/series.php/]]: When aliens from outer space lead by the kooky maniacal Jim Carrey like alien Gakk and his posse of Acme Instant Alien Kreatures invade a small suburban town and hatch a fiendish plot to take over the earth and meet the original cast of "Star Trek", four misfit teens named Zach, Jemmy, Plato, and Chubs set out to stop the invasion, save the world, and show the aliens that the kids of america don't take crap from nobody--And nobody snatchers, either.
197* ''Webcomic/GalacticHustle'': [[https://www.galactichustle.ca/]] A crew of intergalactic monster hunters get their hands on an evil robot. Sci-Fi / Comedy.
198* ''Webcomic/GalacticMaximum'': Adventure InSPACE!
199* ''Webcomic/{{Galaxion}}'': Life. Love. Hyperspace.
200* ''Webcomic/TheGarden'': A science fiction webcomic about an "angel", a "demon", and a deceptively cheery young woman.
201* ''Webcomic/GeneralProtectionFault''
202* ''Webcomic/GenesisChronicles'': A MassivelyMultiplayerCrossover starring Emiko Kawasaki, a young agent of an inter-dimensional police force whose job it is to protect against [=DUBs=].
203* ''Webcomic/GenocideMan'': In a world devastated by biological warfare augmented soldier-biologists are used to exterminate genetic "deviants". But then one Genocide Man decides to call it quits and is now on the run from his former organization.
204* ''Webcomic/GetMedieval'': A group of HumanAliens, on the run from the mob, get stranded in fourteenth-century Europe. (France, mostly.) Finished, then went on reruns with author's commentary, also finished.
205* ''Webcomic/{{Gifted}}'': [[http://www.giftedcomic.com]] A young man tries to attend college in a world where anyone can become a superhero at the drop of a hat.
206* ''Webcomic/GhostJunkSickness'': Two bounty hunters badly do their jobs in a world ravaged by a cataclysm 5 years past.
207* ''Webcomic/GiftsOfWanderingIce'': Webcomic about post ice age era and various stuff melting icebergs bring to the shores.
208* ''Webcomic/AGirlAndHerFed'': People in a federal government program are losing their ability to think and feel for themselves. But why are they watching the Girl, and why is she talking to the ghost of Benjamin Franklin?
209* ''Webcomic/GirlGenius'': In a [[SteamPunk Gaslamp Fantasy]] Victorian world that never was, hapless Transylvania Polygnostic U. student Agatha Heterodyne discovers that she has inherited her long-lost father's talent for [[MadScientist Mad Science]]... and his numerous enemies. Started out as a [[ComicBookTropes print comic]] before making its way to the web. Noted with great favor for updating exactly when promised, at the stroke of midnight, three days a week.
210* ''Webcomic/GirlsInSpace'': A Space girl and her Earthling friend have exciting space adventures in their upgraded VW Camper Van.
211* ''Webcomic/{{Glaria}}'' [[http://glaria.thecomicseries.com/comics/]]: Human Joseph Reik is (or claims to be) an investigator probing corruption at a major industrial complex. Elizabeth is a vulpine maintenance technician that Joseph has talked into helping him sneak into the building. When a large robot takes a dislike to Elizabeth, she begins to question her involvement...
212* ''Webcomic/TheGlassScientists'': In VictorianLondon, Dr. Henry Jekyll tries to reform the image of mad scientists, while harboring a dark secret of his own...
213* ''Webcomic/GloriousBounty'': What happens between the jobs to four [[BountyHunter bounty hunters]] who can't stand each other. Updates Tuesdays and Thursdays.
214* ''Webcomic/{{Gnoph}}'': A girl named Abbey and [[TheSymbiote the symbiote]] living inside her try to head back to her homeworld to save both their lives, picking up a few companions on the way. The mood alternates between light humor and dark grotesquery, with a side helping of romance.
215* ''Webcomic/{{Goats}}''
216* ''Webcomic/GodHatesAstronauts'' [[http://www.godhatesastronauts.com/]]: Superheroes who has the important job of keeping farmers from going to space.
217* ''Webcomic/GodTm'' [[http://theoryofeverythingcomics.com/god/]]: Someday, the intellectual property of God will be owned by a certain animation, media, entertainment, and theme park corporation. The Apocalypse is looming, and it's up to Reverend Joeb Kim CPA, an ordained minister in the Sacred Order of Accounting, to stop it.
218* ''Webcomic/GoneToGround''
219* ''Webcomic/GoneWithTheBlastwave''
220* ''Webcomic/GooberAndCindy'' [[http://www.gooberandcindy.com]]: Science fiction, pop culture, food, annoying sister. A comic about an earthgirl and her adopted alien brother.
221* ''Webcomic/GoodShipChronicles'' A webcomic about the life on the spaceship Gossamer, a.k.a. 'The only dead end in space', a.k.a. 'The final stop for dying [[MegaCorp Star Corp]] carreers'. Kinda like ''Franchise/StarTrek'' if it were set in a CrapsackWorld and the Enterprise was crewed by a RagtagBunchOfMisfits.
222* ''Webcomic/Goost26'' [[http://goost26.blogspot.com/]]
223* ''Webcomic/GravityBreakCataclysm'' A sci-fi webcomic about gravity-bending catgirls.
224* ''WebComic/GreasySpaceMonkeys'': Slacker maintenance guys in space.
225* ''Webcomic/TheGreenEyedSniper'': [[http://ges.smackjeeves.com/comics/2541452/cover/]]: A webcomic set in a parallel universe where Ancient Egyptian culture has influenced the world for far longer than our Earth. Sekhmet and Shanti, the main characters, deal with dirty warfare and belong to an engineered species, called A.I.M.S., endowed with amazing strength and the ability to heal at an accelerated rate. The species has many more characteristics which cannot be listed at this moment, due to spoilers.
226* ''Webcomic/GunnerkriggCourt'': A sci-fi/UrbanFantasy hybrid set in a British boarding school resembling a massive industrial complex. As two girls, Antimony and Kat, investigate strange goings-on involving shadow creatures, robots, creepy classmates, and body-snatching demons, they find themselves in the middle of [[JigsawPuzzlePlot a larger mystery]] involving the school and [[MysteriousParent both their parents]]. Despite the heavy plot implied by the previous sentence, the format of the strip is mostly SliceOfLife.
227* ''Webcomic/GurralTheSmasher'': A webcomic about a kaiju gladiator fights who fights at the behest of his alien masters to satiate his addiction to a rare mineral.
228* ''Webcomic/GurralVsSleipnir'': A crossover between ''Gurral the Smasher'' and ''Sleipnir: Equine Invader from Jupiter''
229* ''Webcomic/HalfMan'': A half alien cyborg fights humanity enemies and his own demons.
230* ''Webcomic/{{Harbourmaster}}''
231* ''Webcomic/{{Heist}}'' - superpowered PhantomThief takes on the greatest job of his career -- heisting an artifact of power from the SpaceStation base of [[JusticeLeague Pax]] [[{{Expy}} Americana]]. Hilarity Ensues.
232* ''Webcomic/HelixIndustries'': [[PunkPunk Biopunk-themed]] science fiction with PsychicPowers thrown in. Set in a {{dystopia}}n city TwentyMinutesIntoTheFuture and follows a mentally unstable young woman who was the subject of a mysterious experiment.
233* ''Webcomic/HeroByNight''
234* ''Webcomic/HeroesUnite'': It also has other webcomics in its universe:
235** ''Webcomic/{{Acrobat}}'': After the death of his mentor, a sidekick decides to continue fighting. But is he prepared for the world that awaits him?
236** ''Webcomic/TheBlondeMarvel''
237** ''Webcomic/{{Dasien}}'': A nigh-invulnerable blonde in a {{Stripperiffic}} red suit fights crime.
238** ''Webcomic/{{Energize}}''
239* ''Webcomic/HeroMaterial''
240* ''Webcomic/His7Valkyries''
241* ''Webcomic/{{Homestuck}}'': Four teenagers play a video game that brings about the end of the world. And things only get more complicated from there.
242* ''Webcomic/{{Ice}}'': In [[AfterTheEnd bleak, dystopian]] future England a pair of washouts get caught in the struggle between powerful people to be the one who fixes it all.
243* ''Webcomic/IMew'': A smartphone that turns the owner into a cat.
244* ''Webcomic/ImprintChronicles'': Hayden Bliss is a fugitive of his own apartment who's been HearingVoices all his life, and is trying to find an explanation.
245* ''Webcomic/ImStrangeAndSoAreYou'': A comic about fringe science, internet friendship, and pursuing The Truth. Or, a chat group consisting of four UFO conspiracy theorists try to get their lives together long enough to plan their very first meet up.
246* ''Webcomic/TheInexplicableAdventuresOfBob'': ActionSurvivor Bob Smithson is a WeirdnessMagnet (or rather, the roof of his house is), whose life has filled with [[Franchise/{{Alien}} aliens of various kinds]], robots, TheMenInBlack (agents [[PunnyName Ben and Jerry]]) and genetically engineered creatures, one of which is now his adopted daughter. Cute and silly but with surprisingly likable characters.
247* ''Webcomic/{{Inhibit}}'': A superpowered teenager becomes involved with a mysterious arsonist.
248* ''Webcomic/{{Inhuman}}'': Very complex and character development-heavy sci-fi webcomic that contains its fair share of action scenes as well. The art style is unique and improved considerably over the course of the comic. Contains explicit violence and some suggestive content, so it's recommended for readers aged 16 years old or more.
249* ''Webcomic/InkProofCannon'': A sci-fi/horror anthology webcomic.
250* ''Webcomic/InOurShadow'': 50,000 years after humanity destroys itself a small group of marsupials search for lost human technology that can bring down the Rat Empire.
251* ''Webcomic/{{Insecticomics}}'': A ''Franchise/{{Transformers}}'' PhotoComic that mixes comedy and deconstruction/mocking of the ''Transformers'' fandom itself.
252* ''Webcomic/InternationalComicContinuity'': A large collection of intertwined webcomics that take place in an alternate dimension filled with [[RidiculouslyHumanRobots humanoid]] [[{{Toys/BIONICLE}} bio-organic]] beings.
253* ''Webcomic/{{Intragalactic}}''
254* ''Webcomic/TheIntrepidGirlbot'': The day-to-day life of a young RobotGirl with body image issues told [[SilenceIsGolden entirely without dialog.]]
255* ''[[Webcomic/RoomiesItsWalkyJoyceAndWalky It's Walky!/Joyce and Walky!]]'': The former is about an MildlyMilitary organization of twenty-somethings that fights aliens in a [[UnmasquedWorld gradually less secret]] war. The latter is about the fallout.
256* ''Webcomic/IrregularWebcomic'': This comic, written by Australian physicist David Morgan-Mar, is unique in that the artwork is composed of, not drawings, but {{Franchise/LEGO}} mini-people and figurines from table-top role-playing game sets. The stories use plot arcs to parody many classic films and pop-culture icons, most notably ''Franchise/StarWars'', Film/JamesBond and the late Steve Irwin. {{Pun}}s and cerebral {{Technobabble}} humor are the order of the day.
257* ''WebComic/IslaAukate'': An island of furries is embroiled with a war with aliens.
258* ''Webcomic/IWantADrink'': Drink #274 grows tired of their sea sponge [[EvilOverlord overlord]]'s tyranny. After a failed attempt to hide a fugitive slave, Drink and their two friends are suddenly taken by a mysterious [[MonsterClown demon]].
259* ''Webcomic/ItWasAllYou'': A corporate researcher is tasked with testing a prototype clone designed to love his master, which she begins to reciprocate.
260* ''Webcomic/IWasKidnappedByLesbianPiratesFromOuterSpace'': Megan Rose Gedris originally started it as a [[SatireParodyPastiche cheesy parody/affectionate pastiche]] of 1950s sci-fi pulp paperback comics featuring pirates, aliens, and lesbians, but the comic has gone through CerebusSyndrome.
261* ''Webcomic/JennyAndTheMultiverse''
262* ''Webcomic/JesusChristInTheNameOfTheGun''
263* ''Webcomic/{{Jix}}'': A blue-furred alien princess with multiple personalities in New York.
264* ''Webcomic/JoyRide''
265* ''Webcomic/JumpLeads'': British sci-fi comedy in the style of ''Series/RedDwarf'' or ''Franchise/TheHitchhikersGuideToTheGalaxy'', ''Jump Leads'' is the tale of two trainee dimensional travelers who are stuck jumping between random parallel universes, trying to find their way home.
266* ''Webcomic/TheJupiterPalladium'': Superhero comic focusing on a team of superhumans in an {{Adventure Town|s}}.
267* ''Webcomic/{{Katinka}}'': As the author describes it: ''Katinka'' is a story about animals living on different planets. But the planet the dogs were supposed to rule are under attack! Silver, Katinka's father and king of her planet, is a great warrior and helps his dog-friends in need. The attacker remains unknown, so Katinka and her new friends went off to find out who initiated the attack and how they can prevent attacks. A long journey lays ahead, full of colorful characters and dangerous adventures in which Katinka and her friends will be quested to recreate a planet that was once known as Paneruga.
268* ''WebOriginal/KeitAi'': [[http://www.webtoons.com/en/challenge/keit-ai/list?title_no=36825]] The sci-fi webcomic derivative of the infamous Website/FourChan [[MemeticMutation meme]] [[{{Snowclone}} copypasta]]. It involves lovers from {{Alternate Universe}}s who can [[LongDistanceRelationship only contact]] each other through [[DeusExMachina cellphones]] that [[TheMatchmaker agree to make]] their {{alternate sel|f}}ves fall for... themselves.
269* ''Webcomic/KerKylsWatch'': A comic involving time traveling middle school students who have to save the world.
270* ''Webcomic/KiddCommander'': A shonen-style adventure comic about a bunch of silly people on a trip to catch the sun, whatever that means.
271* ''Webcomic/KilaIlo'': Aliens find out Earth is inhabited.
272* ''Webcomic/KiwiBlitz'': A comic about a girl and her [[AnimalMecha kiwi bird-shaped Mecha]].
273* ''Webcomic/{{Knighthood}}'': Detailing Joy's adventures to becoming a knight.
274* ''Webcomic/KnowledgeIsPower'' [[http://www.kip-comics.com/index.php]]: a group of college students gain superpowers based on their homework assignments at the time that an EldritchAbomination tries to break into their universe.
275* ''Webcomic/LadySpectraAndSparky'': A mother-and-daughter team of hi-tech superheroes.
276* ''Webcomic/LasLindas'': Detailing Mora Linda's ongoing efforts to run a dairy farm.
277* ''Webcomic/TheLastCowboy'': In an alternate history, a disease has rendered most of Earth's women sterile. With the human race becoming an ever-shrinking minority in the Galactic Alliance, a small group begins fighting for the lives of another race which has just been discovered. Completed in 2020.
278* ''Webcomic/TheLastHumaninaCrowdedGalaxy'': The last human is a little girl named Sarya, whose adopted mother Shenya is a terrifying spiderlike alien who would do anything to protect her daughter.
279* ''Webcomic/LastRes0rt'': Mysterious Chick signs up for a DeadlyGame RealityShow, competing with a bunch of condemned criminals... ''then'' finds out she's a vampire on top of all this. Supposedly the internet's first/only {{Cyberpunk}} UsefulNotes/{{furry|Fandom}} comic, although the supernatural aspects feel very much at home in all of this.
280* ''Webcomic/TheLawOfPurple'': Some stories begin in school, or someone's apartment. This one starts on a spaceship. Follows Red, Blue, Green, and Whitey as they start a new life as refugees in hiding...on Earth. Mixes humor and serious topics.
281* ''Webcomic/LeagueOfSuperRedundantHeroes'': A comic about a city where the heroes are idiots, the villains are morons and HilarityEnsues whenever the two sides meet.
282* ''Webcomic/LeavingTheCradle'': A story about unfortunate FirstContact with aliens, trying to bring together space opera and realism.
283* ''Webcomic/LegostarGalactica'': A {{Franchise/LEGO}} pastiche not only of ''Series/{{Battlestar Galactica|2003}}'', but also of ''Franchise/StarWars'' and other science fiction franchises.
284* ''Webcomic/LegoSpaceTheComic'': As the name implies, a comic that gives a story to {{Franchise/Lego}}'s long-running Space line.
285* ''Webcomic/{{Level}}'': Government conspiracy, underground civilizations you have to parachute to, and people turning into silly putty.
286* ''Webcomic/LifeAfterEarth''
287* ''Webcomic/LiquidMercury''
288* ''Webcomic/TheList'': The story of Levi Cole, an assassin that targets superheroes.
289* ''Webcomic/LittleRobotBigScaryWorld'': A story of a cute little robot named BIP suddenly thrust into an adventure.
290* ''Webcomic/{{Lizzy}}'': Follows the adventures of country girl and possible TykeBomb Lizzy as she travels to the big, dirty, {{Cyberpunk}} city. The Evil Empire has taken a mysterious interest in her. Nonlinear storytelling hints that it may involve TimeTravel.
291* ''Webcomic/{{LOGOS}}'' [[http://logoscomic.smackjeeves.com/comics/1084500/logos000-1/]]: In the far future, on a distant planet, a man made of plastics discovers what it truly means to be human. Some nudity, some violence, as such some pages NotSafeForWork. Updates daily.
292* ''Webcomic/LongExposure'': A comic about a nerd and his bully who are forced to pair up in a school project, and after an incident, start to develop supernatural powers.
293* ''Webcomic/LoveAndCapes''
294* ''Webcomic/{{Lovebot}}'': Set in 2049, it follows the robot repairman Xada and how his life changes when he's asked to work on one of the latest in a line of RidiculouslyHumanRobots, and how his life changes when that robot unlocks his sentinence, goes on the run, and falls in love with him.
295* ''Webcomic/{{Lovelyss}}'': "A sexy outer-space nightclub pulp adventure in three part(ie)s."
296* ''Webcomic/{{Lovesyck}}'': A prequel to Lovelyss by the same author. Based around the clubship Carrier 9 and the criminals, gangs, party-goers and undercover police involved in complex schemes and politcal intrigue.
297* ''Webcomic/LoveNotFound'': A romance sci-fi set in the far future on a planet with a human population so small and so technologically dependent that they no longer even touch. Abeille, the main character, is awoken to her need for human contact and seeks out that missing human connection.
298* ''Webcomic/LuminaryChildren''
299* ''Webcomic/TheLydianOption'': Comic about a small group of human prisoners in an asteroid prison dominated by hostile aliens.
300* ''Webcomic/M9Girls'': A sci-fi meets magical girl webcomic about a team of college researchers who gain the ability to absorb and channel the primordial energy of the universe by way of scientific research.
301* ''Webcomic/AMadTeaParty'': Sci-fi comic about two genetically engineered girls caught between various hostile political factions (and some aliens) in future Japan.
302* ''Webcomic/{{Magellan}}'': Newcomer Kaycee Jones joins students at the SuperheroSchool Magellan Justice Academy to train to become a part of the elite Force Magellan.
303* ''Webcomic/{{Magience}}'': A webcomic about a [[MassivelyMultiplayerOnlineRolePlayingGame MMORPG]] that may be more than a game.
304* ''Webcomic/MagIsa'': A webcomic about crazy people who get [[http://www.drunkduck.com/MAG_ISA/index.php?p=589522 chips]] planted in their heads.
305* ''Webcomic/{{Manmachine}}'': A hard science fiction epic incorporating global politics, artificial intelligence, and an electronic music score, at fightevilwithevil.com.
306* ''Webcomic/MareInternum'': Graphic novel about the isolated inhabitants of the planet Mars.
307* ''Webcomic/{{Marooned}}'': The humorous and touching tale of Captain John and his sidekick robot, Asimov (along with an ensemble cast) who become stranded on Mars.
308* ''Webcomic/MarshRocket'' [[http://www.marsh-rocket.com/]]: Gritty futuristic setting revolving around a ''Film/PulpFiction''-esque Suitcase, with distinctive art style and a degree of sci fi hardness (while characters have portable forcefields, they have clear limitations, and no lazer guns).
309* ''Webcomic/MassEffect3Generations'': Claimed FixFic for the controversial ending of ''VideoGame/MassEffect3''.
310* ''Webcomic/MaxZing'' [[http://www.drunkduck.com/Max_Zing/5387172/]]: A nice young space tyrant inherits a planet and, following in the footsteps of his idol Ming the Merciless, sets out to conquer the universe. Only without inconveniencing anyone. Written by a Canadian.
311* ''ComicBook/{{Meanwhile}}'': An [[{{Gamebook}} interactive story]] about a boy who, on a chance visit to a MadScientist's house, is given the opportunity to test a few inventions. Written by Creator/JasonShiga.
312* ''Webcomic/MechagicalGirlLisaANT'': involves a "[[MagicalGirl Magical]] [[{{Otaku}} Girl]]," a 4-inch-tall alien ant mentor, and human-sized mecha.
313* ''Webcomic/{{Melonpool}}'': The adventures of the incompetent crew of the Steel Duck. One of the earliest sci-fi webcomics; it was rebooted in 2012...
314* ''Webcomic/{{Memoria|2010}}'': Three children find a house in the woods where a witch is said to live. When the younger boy vanishes, the house is gone -- and the older two set out to find him. They soon learn it's psionic powers, not magic -- and they've got it.
315* ''Webcomic/{{Messenger}}'': A runaway girl, her dead best friend, and a group of genetically altered creatures try to survive in Earth's distant future.
316* ''Webcomic/MessPerfect'' [[https://www.deviantart.com/epantiras/gallery/26672451/mess-perfect-parody-comic]]: In this parody comic of ''Franchise/MassEffect'', a frustrated-at-Creator/BioWare gamer girl chronicles her Shepard's experience through the game series.
317* ''Webcomic/{{Metempsychosis}}'': A collection of interconnected short stories, following the themes of reincarnation, dreams, and extradimensional travel. One of the main characters so far is a {{Humanoid Alien|s}} who is on chasing down a [[FeatheredDragons dragon-like creature]] for as of yet unknown purposes.
318* ''Webcomic/MetompsychosisUnion'': {{Cyberpunk}} with [[ScienceFantasy fantasy elements]], where the rich and powerful all but own the rest of humanity.
319* ''Webcomic/{{Millennium}}'': As Luzio and his first mate Sage travel the galaxy helping those in need, they seek answers about the mysterious, ever-looming presence of an evil scientist from Sage's past.
320* ''Webcomic/MindMistress'': Mentally challenged girl gets device that can turn her into smartest person on Earth, but if she don't change back for seven days, she will die from brain cancer.
321* ''Webcomic/MinionsAtWork'' [[http://www.minionsatwork.com/]]
322* ''Webcomic/MinorActsOfHeroism'': The hilarious adventures of three twelve-year-old superhero sidekicks, as they find out who each other are, hang out, and try to stop the BigBad from killing people without dying, so far. Beautiful, well-colored drawings.
323* ''Webcomic/AMiracleOfScience'': Set in 2148, a detective from Earth and a technologically enhanced psychiatrist from the hive mind of Mars track down a stereotypical mad genius bent on stellar control. This webcomic taps into the psyche of a MadScientist, and the science of memetics, which can be used to cure (or cause) psychological issues. The comic even made a name for it: ScienceRelatedMemeticDisorder (or SRMD, for short). Ran from 2002 to 2007, with notable comments from the author and artist.
324* ''[[Webcomic/MisfitsGuild Misfits' Guild]]'': A superhero comic about a teen with [[ShockAndAwe lightning powers]]. So far, contains no actual superheroes.
325* ''Webcomic/MissMelee'': superheroic adventures of a mom
326* ''Webcomic/AMomentOfPeace'': A [[AfterTheEnd post-apocalyptic]] [[BoyMeetsGirl romantic]] [[SliceOfLife slice of life]] that involves [[OurMonstersAreDifferent monsters]] and [[TropePantheons gods]].
327* ''Webcomic/{{Monstar}}'': In Australia, green-eyed Monstar deals with everyday life, hangs out with his friend Bunnee, and occasionally saves the world.
328* ''Webcomic/TheMonsterAndTheGirl'': Adventures of an immortal technomagical {{Cyborg}} created by an alien god and the woman he's vowed to protect. In every lifetime that he finds her. Monochrome shades of grey, improving in appearance with rapid ArtEvolution. OELManga created and written by an author/artist in Japan.
329* ''Webcomic/MonstersGarden'': The chronicles of a [[BadAss professional fighting champion]], a [[{{Adorkable}} strange robot]], [[DeadpanSnarker an engineering student who is well versed in the art of sarcasm]] and a [[CloudCuckooLander weirdo soldier.]] Ongoing.
330* ''Webcomic/{{Moumantai Motherfuckers}}'' Ongoing furry comic about an alien rock band playing their music across the universe.
331* ''Webcomic/{{The MOTHER Principle}}'' [[http://www.motherprinciple.com/]]: A new beginning we must bring to an end.
332* ''Webcomic/MyLifeAtWar'': Betsy-Ray is a mecha pilot for the 1st Investment Recovery Battalion, a mercenary company. Giant robots and capitalism.
333* ''Webcomic/MyRoommateIsAnElf''. Though it's more on science fantasy, they live on a terraformed planet that is a colony of a spanning empire.
334* ''Webcomic/{{Narbonic}}'': Answering an innocent job offer, Dave Davenport is drawn into a shocking spiral of vice, crime and moral depravity. Hopelessly ensnared by a madwoman's feminine wiles, can he return to the world of sanity before it is... too late? Formerly on a subscription site, the story ended in late 2006, whereupon the entire archive was made free. Highly recommended! Available in archive form and in reruns with author's commentary.
335* ''Webcomic/{{Nebula}}'': The adventures of UsefulNotes/TheSolarSystem, who are all GeniusLoci.
336* ''Webcomic/NebulaBeings'': Webcomic about two aliens who travel the galaxy to achieve their goals.
337* ''Webcomic/NeoKnights'': Semi-superhero/slice-of-life webcomic about the titular team as well as their lives off-duty and their relationships with each other. Contains snake-women, robot dreams and knifeguns.
338* ''Webcomic/NeoKosmos'': Human kids are raised in captivity by alien scientists in space.
339* ''Webcomic/NeverMindTheGap'': Small-town romance in a sci-fi setting. With robots. Fairly [[MediaNotes/MohsScaleOfScienceFictionHardness hard]].
340* ''Webcomic/NewAmerica'': A story of captives and a dysfunctional family, taking place in and around a human colony on the planet Novaus.
341* ''Webcomic/NinePlanetsWithoutIntelligentLife'': A philosophical road comic about two unemployed robots on an improvised interplanetary voyage of self discovery.
342* ''Webcomic/NotAVillain'': As the author puts it: A reformed hacker, an addictive virtual game, can she stay honest?
343* ''Webcomic/NotSoDistant'': As the author puts it: It's a story about time travel, everyday life and an alien failing at integrating into human society.
344* ''Webcomic/NothingComesNaturally'' [[http://nocona.comicgenesis.com/]]: Furry science fiction, apparently lost. The only working page at the linked site is advertising a move to a new site that has no content at all.
345* ''Webcomic/NotWhatIWas''
346* ''Webcomic/Nova44'': Rock'n'roll music battles in space.
347* ''Webcomic/ObsidianBlaze'': In a bleak dystopian future, Tokyo is ruled by a massive corporation called Pyrite Industries, and people with superpowers are forced to hide their abilities. One of these people is Obsidian, a man with no memories and a hatred for Pyrite.
348** ''Webcomic/OldSchoolMelonpool'' ...with the original 1996-2012 comic remaining available in printed form.
349* ''Webcomic/OceansInTheSky'': A rather new webcomic featuring talking dolls, {{Space Pirates}} and a [[{{spaceisanocean}} flying boat]].
350* ''Webcomic/OHumanStar'': A transhumanist gay romance.
351* ''Webcomic/OnASunbeam''
352* ''Webcomic/OneWay'': A sci-fi gag strip with an underlying story about making first contact with aliens and a government conspiracy
353* ''Webcomic/OnlyHuman'': A story about two MechanicalLifeforms taking care of the last human girl in the world.
354* ''Webcomic/OperationReboot'': A brother and sister move into a house that turn out to have a secret lab hiding a RobotGirl and an AI.
355* ''Webcomic/{{Opplopolis}}'': An esoteric ensemble of characters in [[CityOfAdventure a city called Opplopolis]] encounter the word [[MacGuffin "marvedyne"]] in various ominous ways and try to figure out what it means. By the author of ''Webcomic/NinePlanetsWithoutIntelligentLife''.
356* ''Webcomic/{{Orbit}}'': A comedic webcomic featuring the planets in our solar system, with the main storyline following Earth's mid-life crisis.
357* ''Webcomic/TheOrderOfTheBlackDog'': A CosmicHorror story set in a futuristic alternate Egypt.
358* ''Webcomic/OurIntrepidCrew''
359* ''Webcomic/OutlastTheMurkoffAccount'': A six-issue webcomic set in the background of ''VideoGame/{{Outlast}}'' and ''VideoGame/OutlastII'', following the recollections of the Pauls, a couple of [[ResearchInc Murkoff Corporation]] insurance officers.
360* ''Webcomic/OutOfTheDeadLand'': A PhotoComic about the end of the ''Franchise/{{Transformers}}'' war, using only toys from the Transformers Alternators line. No link; comic may be lost.
361* ''Webcomic/{{Outrim}}'': A [[MediaNotes/MohsScaleOfSciFiHardness hard science fiction]] comic about [[FunnyAnimal genetically uplifted rodents]] operating a scruffy space freighter. Lots of [[ShownTheirWork shown work]], recommended. Ended in December 2008.
362* ''Webcomic/{{Outsider}}'': The adventures of a castaway [[FishOutOfWater human ensign]] trying to negotiate for humanity in a galaxy at war... and one misstep, much less choosing the wrong side, could have unpleasant [[EarthShatteringKaboom consequences]].
363* ''Webcomic/{{Outissa}}'': A webcomic about transformation, xenophilia, and monsters.
364* ''Webcomic/{{Outworld}}'': A SpaceOpera featuring furry characters.
365* ''Webcomic/OwensScrapbook'': A SpaceOpera about a group of humans surviving in space after the Earth is blown up. Think ''ComicBook/TheWalkingDead'' mixed with some ''Franchise/StarTrek''. (Note the ArtifactTitle.) No link found.
366* ''Webcomic/PaoniaPawns'': A sci-fi webcomic featuring time travel, alternate universes, and the Four Horsemen of the Apocalypse. A long-running webcomic which reached 1800 strips before (mostly) wrapping up its plot.
367* ''Webcomic/{{Parallels}}'': Keeping the spaceways safe one universe at a time.
368* ''Webcomic/{{Parhelion}}''
369* ''Webcomic/ParticleFiction'': 'A monthly comic book that just happens to be online' which passes through a variety of genres, including Sci-Fi.
370* ''Webcomic/PastelDefenderHeliotrope'': A superpowered living sex doll in a human colony in a bizarre alien universe.
371* ''Webcomic/PatchworkChampions'': In a world rife with {{superhero}}es, two known as Timebender and Lucky Ladd try to make a living and fight crime in their home city.
372* ''Webcomic/PetProjects'': Focuses on a witch named Notle, and her troublesome pets, Kaeley the Cat, and Spike Beagle.
373* ''Webcomic/{{Pilot}}'': About the adventures of [[ProtagonistTitle the robot of the same name]], and his adventures in [[TwentyMinutesIntoTheFuture the world of 2025.]]
374* ''Webcomic/PlanetB'': Four alien friends try to make their planet a better place.
375* ''Webcomic/PlanetOfHats'': Recaps all episodes of ''Series/StarTrekTheOriginalSeries''. By the author of ''Webcomic/IrregularWebcomic'' and ''Webcomic/DarthsAndDroids''.
376* ''Webcomic/PlungerPup'': A dog, a magic plunger, and a universe of evil. No link found.
377* ''Webcomic/ThePocalypse''
378* ''Webcomic/PowerNap'': A man with a menial job, and sleep deprivation because of an allergy to a [[GovernmentDrugEnforcement mandatory]] sleep-replacement drug, struggles to maintain his sanity in a corporate {{Dystopia}}.
379* ''Webcomic/PowerPills'': Taking a pill at a party gives Caleb Budde superpowers.
380* ''Webcomic/ProjectBlackfire'': A group of supervillains run a criminal mercenary organization as they struggle with human vulnerabilities and internal senses of morality.
381* ''Webcomic/Project0'': An orphan and his two friends flee across a wasteland to escape persecution, but what they find changes everything...
382* ''Webcomic/{{Pulse}}'': A young woman in training to become a superhero.
383* ''Webcomic/QuantumVibe'': In the year 2523, Nicole Oresme of L-5 City gets job from Dr. O Murchadha involving quantum vibremonics.
384* ''Webcomic/QuentynQuinnSpaceRanger''
385* ''Webcomic/QuestionableContent''
386* ''Webcomic/RagingSeaOfFlames''
387* ''Webcomic/RainbowFire'' [[https://www.webtoons.com/en/challenge/rainbow-fire/list?title_no=327177]]: Sci-fi comedy set in a {{Cyberpunk}} future. Members of a space-based government-funded intelligence organization (spies, if you will) attempt to survive the rigors of day-to-day life.
388* ''Webcomic/RalfTheDestroyer'': Ralf has been hired by the [=TransGalactic=] Council to destroy the planet Earth. What they didn't know is... he's actually really a nice guy and kind of a procrastinator.
389* ''Webcomic/RavenWolf''
390* ''Webcomic/RayFox''
391* ''Webcomic/ReBootCodeOfHonor'': A sequel to ''WesternAnimation/ReBoot''.
392* ''Webcomic/RecklessYouth'' [[http://recklessyouth.gronkcomics.com/]]: A British comedy-adventure-fantasy series about an IdiotHero and his friends.
393* ''Webcomic/{{Redd}}'': A big-boobed researcher who was born without arms fights sea monsters and other evil stuff with her [[RaymanianLimbs floaty hands of science]] and other gadgets that translate neural signals to instruments.
394* ''Webcomic/RedSpaceBlues'': A group of space mercenaries get into dangerously wacky adventures.
395* ''Webcomic/RedsPlanet'': A rebellious red-haired girl, abducted by aliens, ends up stranded with an assortment of aliens on another planet.
396* ''Webcomic/RelativelyIrrelevant'' [[http://failaward.net/]]: ''Chaos Theory'' (a reboot of the earlier ''Theory of Relativity'' series) follows a time traveller as he meddles with time paradoxes, encounters alien beings and panics around murderous simulant androids.
397* ''Webcomic/{{Relativity}}'': A woman sets off on the first manned lightspeed flight, with unexpected consequences to herself and her marriage.
398* ''Webcomic/RenovaCaeli'': A story set-up 1000 years after WWIII where humans damaged the space itself. It follows the tale of a young man forced to depart in order to discover the truth about what happened during the War, and the Empire's implication in it. Link not found.
399* ''Webcomic/{{Requiem}}'' [[http://requiem.spiderforest.com]]: Sci-Fi/Alternate Universe webcomic that follows a group of people trying to prevent an extinction level event.]]
400* ''Webcomic/ResNullius'': A human and an alien, survivors of a genocidal war, try and eke out a living while on the run from the race that wants them dead.
401* ''Webcomic/{{RetroBlade}}'' [[http://retrobladecomic.com]]: Join a [[CommandRoster team]] of time travelling misfits on their adventures, as they [[ApocalypseHow/ClassZ quest to restore reality.]]
402* ''Webcomic/ReversedStar'': A webcomic that follows the stories of Evangeline Dumont, a kidnapped heiress, and Icaruss, the human/alien hybrid determined to save her.
403* ''Webcomic/RezzAndCoBountyHunters'': A group of bounty hunters doing odd jobs and adventures.
404* ''Webcomic/RimworldTales'': A webcomic based on the game ''VideoGame/RimWorld'', following a variety of characters in their struggle to survive.
405* ''Webcomic/RobertRankinsEmpires'': The tales of the masked vigilante Lady Raygun, as [[ItMakesJustAsMuchSenseInContext she protects the interstellar British Empire from all the villains named Jack that threaten it]].
406* ''Webcomic/RobottoJukujo'': Robot MOM, she cooks, she cleans she kicks robot butt in the arena
407* ''Webcomic/RomanticallyApocalyptic'': An [[AmbiguousGender ambiguously-gendered]] {{Cloudcuckoolander}} and his/her subordinates wander the devastated wastelands of a post-apocalyptic setting and try to entertain themselves amongst the nothingness of their world.
408* ''Webcomic/RoninGalaxy'': A group of [[StreetSamurai futuristic ronin]] wander the galaxy seeking mercenary work with the promise of adventure and cold hard cash.
409* ''Webcomic/RonPlanet'': The last astronaut on Earth is commissioned by NASA to investigate suspicious activities on the moon. Created by the Brothers Chaps (the creators of WebAnimation/HomestarRunner) and their friend Craig Zobel.
410* ''Webcomic/RootRot'': Three young interns of a secret paranormal investigation agency may be in over their heads when their extracurricular activities turn magically deadly.
411* ''Webcomic/RubyNation'': A sequel of sorts to Ruby Nation, serving as a deconstruction of the teenage superhero narrative.
412* ''Webcomic/RubysWorld'': A teenage girl who gains superhuman powers after a freak lab accident and her friends battle the schemes of the nefarious Beagle Corporation and its twisted genetic experiments.
413* ''Webcomic/{{Runners}}'': A ragtag crew of smugglers are trying to make ends meet when they take on a mysterious girl as cargo. ... If it sounds familiar, it's a coincidence.
414* ''Webcomic/RunawayToTheStars'': A hard sci-fi story about a ragtag crew of aliens and genetically modified humans aboard a ship piloted by a sarcastic AI. But this is only one story in a wider galaxy.
415* ''Webcomic/SacredPie'': Three 20-something humans from our time are sent into the future to find Sacred Objects and defeat the forces of Satan.
416* ''Webcomic/SameNewWoman'' [[http://snw.thecomicseries.com/]]: follows Marita, an ordinary librarian who wakes up one morning with a hyper-muscular body and extraordinary strength. She tries to go on with her old life but finds her world increasingly out of control.
417* ''Webcomic/{{Skarpworld}}'' [[https://gerph.gumroad.com/?sort=newest&tags=comic/]]: follows Dumfer, a young man who was roped into helping an alien girl to film the finest adult films.
418* ''Webcomic/{{Sarab}}'': Sarab lives in a world where humanity has nearly destroyed nature and now uses technology to conserve it. Has focused on humor and action sequences so far, to great effect.
419* ''{{Webcomic/Sarilho}}'': An alien gets shot in the face four times and for some reason that starts a war. It's got Future Romans!
420* ''Webcomic/SchlockMercenary'': [[MediaNotes/MohsScaleOfSciFiHardness Fairly Hard]] ScienceFiction in [[TheFuture the 31st century]]. Stars, among others, an alien with BizarreAlienBiology, a MadScientist and TheCaptain. Consistent humor, and we mean ''consistent'' -- ''Schlock'' has been running [[ArchivePanic seven days a week, without missing a day, since the year 2000]]. Even when a transformer blew it updated off-site at his blog and in various other places.
421* ''Webcomic/SarahZero'': In TheFuture, TheInternet has been shut down and replaced by a [[MegaCorp corporation-controlled]] pay-to-play network called the Contranet, which is so integrated with daily life that interpersonal relations have been reduced to shallow friend whoring. Meanwhile, Sarah Zierinski tries to work out her own emotional problems and run a nightclub without being destroyed by [[KillerRobot killer robots]] or horse assassins. Notable for its liberal use of the DesignStudentsOrgasm.
422* ''Webcomic/{{Seaglass}}'': A love letter to {{Mecha}} anime and ''Literature/TheLittleMermaid''. Follows Victor Imai, space pirate captain, on his quest to obtain the mythical "Seaglass".
423* ''Webcomic/ShadesOfGray'' [[https://www.theduckwebcomics.com/Shades_of_Gray/]]: Join Ten as he strives to overcome a genetic disability and an uncooperative teammate to become a space fighter pilot. Later pages are text-only; completed 2019.
424* [[http://https://callumquinncreates.com/index.php/siblings-of-steel-home/ Siblings of Steel]]: is a sci-fi mystery webcomic about two robots, Phren and Yoselin, traveling the vast Forsy Empire, solving crimes.
425* ''Webcomic/{{Sidekicks}}'': Even if people are born with superpowers, they must serve as sidekicks of superheroes in order to become superheroes themselves. This is Dream Girl's story.
426* ''Webcomic/{{SIN}}'' [[http://www.mangamagazine.net/manga/1]] : Set after the WWIII, in a time were resources are rare and fought over and humanity is mostly hidding in large, forified cities with a class-society. So far this manga/webcomic has followed two seperate timelines.
427* ''Webcomic/SkinHorse'': From the creator of ''{{Narbonic}}''. An understaffed and underfunded government department attempts to deal with the creations of Mad Science.
428* ''Webcomic/TheSkybox'': A young woman is saved from a plane crash by a gryphon, and taken to the mysterious "Skybox".
429* ''Webcomic/SleipnirEquineInvaderFromJupiter''
430* ''Webcomic/{{Snowfall}}''
431* ''Webcomic/{{Softies}}'': An episodic space-fantasy comic about adventures in waste collection among a universe of alien life. It stars two mammals, one lizard, and a series of jokes.
432* ''Webcomic/SpaceBoy'': A sci-fi webcomic by Stephen [=McCranie=] concerning a girl who lost her best friend to a 30-year cryogenic time gap, and a boy who lost his family to the Nothing.
433* ''Webcomic/SpaceCase'': A normal human accountant takes a job with an alien fuel company, hoping for adventure, but instead finds normal office tedium with stranger co-workers.
434* ''Webcomic/{{Space Kid}}'' : that champion of galactic justice!
435* ''Webcomic/SpaceNavy'' [[http://www.space-navy.com]]: An AffectionateParody of Franchise/StarTrek chronicling a small fleet of [[RagtagBunchOfMisfits second-string]] ships that must cross the [[SpaceIsAnOcean ocean of space]] on their way to save an [[RubberForeheadAliens alien species]] and the universe from [[KillEmAll extinction]] or [[EldritchAbomination worse]].
436* ''Webcomic/SpacePawdyssey'': In a universe of funny animals, a ragtag crew of misfits come together to save the Alliance from itself.
437* ''Webcomic/SpacePulp'': A pulp-y SpaceOpera about interstellar KnightErrant (and JerkWithAHeartOfGold) Iridium Lake and her battle against an evil cyborg empire over the fate of a race of {{Noble Savage}}s.
438* ''Webcomic/SpaceSchool'': A story about two teen boys (well, one's an alien) who attend a school in space and fall in love. [[GrowingUpSucks It couldn't be that easy though]].
439* ''Webcomic/{{Spacetrawler}}'' (Finished): A story about six young adults, kidnapped from Earth to help in a galactic fight to free an enslaved race. Or something. Features adventure and frequent MoodWhiplash.
440* ''Webcomic/SpeakNoEvil'' [[http://theoryofeverythingcomics.com/SNE/]]: In the future, cheap foreign labor is sent to asteroids and planets for mining. This Eisner Award Nominated comic tells the story of one worker as he struggles through a tough and sometimes absurd world.
441* ''Webcomic/SpecialSchool''
442* ''Webcomic/{{SPI}}'': "Your name is Jones. We've brought you here because you're a danger to yourself... and to others. All 'memories' relating to your involvement in several high-profile assassinations are mere delusion, a by-product of your illness. We’re here to make you better. It is time."
443* ''Webcomic/{{Spiddrelli}}'': A thousand years after the 10 great scientists sought to improve the world. The inhabitants now try to cope with the changes the scientists' inventions have made.
444* ''Webcomic/{{Spy6teen}}'': Model High School Student, Cally Calhoon, moonlights as a high-tech super-spy between classes.
445* ''Webcomic/ASrGrafoInTime''
446* ''Webcomic/{{SSDD}}'': Started as a gag-a-day about four idiots in a flat in England, developed a time travel plot tumor that has turned into a military sci-fi story that alternates updates with the original characters.
447* ''Webcomic/StarcrossdDestiny'' [[http://www.starcrossd.net]]: In 2010, after a series of weird murders, five teenagers from New Orleans gained superpowers. Five years later, the teenagers have become outcasts, and with the cops and the Cajun mafia on their tails, they must now use their powers to survive the streets of New Orleans. But little did they knew, that something like they've never seen before is about to happen.
448* ''Webcomic/{{Starfighter}}'': A navigator/fighter pair in a future space station fight in pitched space dogfights while having a rather steamy relationship outside of battle.
449* ''Webcomic/StarHammer'': A high schooler finds a powerful alien hammer and sets out to prove themselves in a world full of advanced humans.
450* ''Webcomic/StarPower'': An ordinary lab assistant on a SpaceStation gains superpowers from a cosmic entity. Mixes SpaceOpera and {{Superhero}} tropes.
451* ''Webcomic/{{Starslip}}'': What Kristofer Straub did after ''Checkerboard Nightmare'', an [[AffectionateParody affectionate]], character-driven sci-fi parody with well-defined arcs.
452* ''Webcomic/StarSomething'': A collaboration between Tropers/{{Webrunner}} and [[Webcomic/RPGWorld Ian Jones-Quartey]], a hilarious parody of every sci-fi trope you can possibly imagine. Unfortunately didn't last very long.
453* ''Webcomic/StarTrip'': A young woman named Jas rescues an alien named Khut from a glowing net. Having sarcastically asked to be given a tour of every ([[BeCarefulWhatYouWishFor habitable]]) planet in the galaxy in return, Khut [[VoluntaryShapeshifting turns into a spaceship]] and starts taking Jas from planet to planet. The universe is surprisingly fleshed-out and includes database entries about each planet visited at the end of their respective chapters. Undergoes major ArtEvolution and CharacterDevelopment over time.
454* ''Webcomic/StarwardLovers'': A young woman falls for a cool and mysterious stranger who frequents the same coffee shop as her, only to discover she's an undercover agent and get pulled into her world of underwater bases and aliens.
455* ''Webcomic/{{Stellarscape}}'': [[CastOfPersonifications Rigel Orion and its crew, Algol, Vega, Procyon and Adhara]] are the members of the Orion Unit, a space-adventuring starship crew on a mission to other worlds.
456* ''Webcomic/SteamgearInc'': A {{Steampunk}} action comic about the greatest tech company in the world, the elite soldiers under their employ, and one woman who strives to become one of those fighters.
457* ''Webcomic/StringTheory2009'': "The disastrous rise of a supervillain superstar". It's basically about the life of a somewhat abnormal scientist who quickly falls into a life of crime and supervillainy.
458* ''Webcomic/StoriesFromTheGoldenGarden''
459* ''Webcomic/StormOverWhoomera'' [[http://stormoverwhoomera.thecomicseries.com/]]: A raiding party of Vord think the worst thing they have to deal with is the human outpost on Whoomera... boy, were they wrong! From Ed Kline, creator of ''Webcomic/TheStormrunners''. No direct story connection despite the similarity in titles. On hiatus since May 2018, and now officially cancelled due to data existence failure.
460* ''Webcomic/TheStormrunners'': A story about Mars (not the one hanging out there now, but a Mars 3.5 billion years ago), a tank commander turned foot soldier, and the crew she picks up along the way... NSFW for nudity. Completed.
461* ''Webcomic/StrongFemaleProtagonist''
462* ''Webcomic/SturgeonsLaw'': A dysfunctional group of ''Film/JamesBond''-style supervillains scheme to take over the world. It's like a [[JustForFun/XMeetsY cross]] between ''WesternAnimation/{{Archer}}'' and ''WesternAnimation/PinkyAndTheBrain''.
463* ''Webcomic/SundownBoys'': Four brothers get swept up in a conspiracy and begin to find out secrets about the De Saule organization.
464* ''Webcomic/SunsetGrill'': The day-to-day life of the staff and patrons of a bar on a dysfunctional future earth. Because at least there's still beer in space.
465* ''Webcomic/SupermassiveBlackHoleAStar'': A hard sci-fi comic in cinematic format, set in the center of our galaxy.
466* ''Webcomic/{{Supermegatopia}}'': Arguably sci-fi, an {{affectionate|Parody}} look at Creator/{{Marvel|Comics}}, Creator/{{DC|Comics}}, and several other big (and small!) name superhero series, done in a funny-animal/furry style. With [[{{Fanservice}} cheesecake]]. ''Lots'' of cheesecake.
467* ''Webcomic/{{Supernovas}}'': Superhero comic about four teens hit with a cosmic MassSuperEmpoweringEvent... and the prisoners in the maximum-security prison nearby who were also exposed to the event. Ongoing and in its infancy as of this writing, so few plot details have been revealed so far, but it appears to be about the teens' adventures as superheroes. Rather like most webcomics...
468* ''Webcomic/SuperStupor'': A DeconstructorFleet of superheroes' and supervillains' stories.
469* ''Webcomic/{{Supertron}}'': A (very) trippy ComingOfAgeStory with robots.
470* ''Webcomic/{{Suppression}}'': A reclusive [[DishingOutDirt sculptor]] teams up an [[PlayingWithFire old]] [[VitriolicBestBuds friend]], a [[AnIcePerson secretive general]], and a soldier who's way out of [[ScarfOfAsskicking uniform]] to unravel the mysteries of a [[TheCorruption plagued]] town. [[RuleOfCool Features giant robots designed to fight]] [[OurDemonsAreDifferent demons.]]
471* ''Webcomic/SurprisingOcteal'': A young woman gets four extra octopus arms as a super power.
472* ''Webcomic/SurvivalAnxiety'': A comic about life, death, and adventures through space and time.
473* ''Webcomic/SuspiciousLinks'': A young woman is dragged into CyberSpace by a strange entity and made to confront her erotic desires in a strange form of FetchQuest
474* ''Webcomic/SweetAndSourGrapes'': A teenage girl living in the jungle teams up with a centuries-old ghost from an [[AfterTheEnd "ancient"]] civilization.
475* ''Webcomic/Switch2016'': Ned is the superhero, Switch, who isn't all that enthusiastic about being pushed to follow in his mother's footsteps.
476* ''Webcomic/TalesFromTheInterface'': In limitless fantasy, what is the value of a simple thing?
477* ''Webcomic/TeddyAndOlive''[[https://www.webtoons.com/en/challenge/teddy-and-olive/list?title_no=383981]]: Olive, a human girl on a postapocalyptic Earth, encounters "Teddy", a crashed space traveler who resembles a teddy bear. Together they search for his lost family in a world where wild humans are as dangerous as the invading lizard-men.
478* ''Webcomic/{{Temerity}}'': A young SuperSoldier joins with an eccentric and energetic alien mercenary to evade his creators.
479* ''Webcomic/{{Tenacity}}'': A teen bounty hunter with [[{{PlayingWithFire}} fire powers]] searches for answers after her former friend robs a lab.
480* ''Webcomic/{{Terinu}}'': A boy from a genetically engineered race is on the run from both {{Space Pirates}} and his race's creator. Aliens in the series are either {{rubber forehead aliens}} or furries. Beautiful full page black and white comic pages. No updates since 2014.
481* ''Webcomic/{{Terra}}'': A [[LaResistance guerrilla movement]] seeks to stop a corrupt ForeverWar between two powerful governments (humanity and a {{Proud Warrior Race|Guy}}) that is wrecking life in the galaxy for the unaligned races.
482* ''Webcomic/{{Tetsuko}}'': An untested chemical transforms the title character into a beautiful, [[StatuesqueStunner tall]] and [[AmazonianBeauty extremely muscular woman]]. (Occasionally NSFW.)
483* ''Webcomic/ThogInfinitron'': Four million years ago, an alien research team accidentally causes a mammoth stampede that tramples an innocent caveman. When the aliens decide to use their medical unit to repair the damage, Thog is accidentally given cybernetic enhancements.
484* ''Webcomic/TheThrillingAdventuresOfLovelaceAndBabbage'': A hilarious comic that posing the ultimate question: What if Charles Babbage and Ada Lovelace teamed up to fight crime with their massive Difference Engine?
485* ''Webcomic/TheresSomethingAboutTails'': Jake, a Mech rider from another dimension, wakes up and finds himself possessing [[Franchise/SonicTheHedgehog Miles "Tails" Prower]] in a world at war.
486* ''{{Webcomic/Threading}}'': Space opera lesbian romance. Dee is deep in debt to her last employer and on the run.
487* ''Webcomic/TimesLikeThis'': A humor (and sometimes NSFW) comic involving time travel.
488* ''Webcomic/{{Tinyraygun}}'': A space adventure about bright but naive explorer making her way in the galaxy.
489* ''Webcomic/ToSaveHer'': An {{Elseworld}} spin-off of ''Webcomic/UnicornJelly''.
490* ''Webcomic/{{Tove}}'': Tove is a teenage girl who is told by an alien that she is [[TheChosenOne The Chosen One]] to defeat a mysterious evil, Gemhakumem.
491* ''Webcomic/TRandomWatch'': A comic in which a powerful watch causes hilarious transformations.
492* ''Webcomic/TranquilityBase'': Uses the basis of 'What if the UK had participated in and won the Space Race?', moves the focus to a century or two later, and watches it all go downhill from there. A comedy/parody series, though it does have a running storyline with story arcs.
493* ''Webcomic/TransdimensionalBrainChip'': Ulf, idiot everyman, receives a brain chip implant that grants him a [[PsychicLink Psychic Link]] to versions of himself across an exponential number of parallel universes. Though initially comedic, things get [[CerebusSyndrome very crazy very fast]]. Notable for its extreme [[SerialEscalation Serial Escalation]] and {{Transhuman}}ist themes.
494* ''Webcomic/TransposeOperator'': An female amnesiac wakes up in the medical facility of a [[AfterTheEnd post-apocalyptic world]]. She does not have a nice day.
495* ''Webcomic/TransStellar'' [[http://www.transstellar.llamaslap.com]]: Two aliens, a {{Holographic Terminal}} AI, and a telepathic human get hired to smuggle some contraband [[{{Casual Interstellar Travel}} from one world to another]], but end up involved in even more illegal activities. {{Hilarity Ensues}}. Went on hiatus for a couple of months and is now back, having experienced a noticeable {{Art Evolution}}.
496* ''Webcomic/Trevor2020'': A horror/slasher comic about the last day of a leukemia patient. However, things aren't as simple as they seem. BodyHorror ensues.
497* ''Webcomic/{{Tripp}}'': An office worker is stuck in a perpetual acid trip. Things get weirder.
498* ''Webcomic/TroopsOfDoom'': Franchise/GIJoe battles ''Franchise/StarWars'' for {{Franchise/LEGO}} technology.
499* ''Webcomic/TruLifeAdventures'': A war between two time-travel organizations constantly intrudes upon the lives of a group of toy store employees.
500* ''Webcomic/TryingHuman'': A comic dealing with AlienAbduction and TheMenInBlack, as well as the mysterious connection between a translator from the 1940s, an alien and his clone, and a young secretary for the NYPD.
501* ''Webcomic/TurnBackTheSun'': A PerspectiveFlip of ''Film/SpaceMutiny'', with the last humans in the universe traveling through space on a generation ship that is falling apart.
502* ''Webcomic/TwoRooks'': Futuristic crime noir, set in the vice- and poverty-ridden city of Haven, where criminals and corrupt bureaucrats rule. Follows one criminals attempt to do something about this. Great writing, lovely stark black-and-white art with splashes of color.
503* ''Webcomic/UltimateLetdown'': A webcomic about a not-so-evil supervillain seeking to take over the world – from 9 to 5.
504* ''Webcomic/UmlautHouse'': An LGBT romance set TwentyMinutesIntoTheFuture with antigravity and cyborgs.
505* ''[[https://tvtropes.org/pmwiki/pmwiki.php/Webcomic/Underdogs Underdogs]]'': Two young men are outed as supers and try to make their way through a government run training program called the Shoolyard.
506* ''Webcomic/UnicornJelly'': A sci-fi/fantasy comic strip. Starts out cute, but gets a little dark. Okay, ''extremely'' dark and creepy. Includes a well-thought-out alternate cosmology that goes down to the molecular level. Finished.
507* ''Webcomic/{{Unity}}'': A science-fiction strip set in the distant future.
508* ''Webcomic/UnityCircuit'': A sci-fi {{Animesque}} webcomic about lesbians who pilot giant robots.
509* ''Webcomic/UNAFrontiers'': It's 300 years "After the End", and two refugees from a besieged technological haven must seek help for their people in a surface world society stuck in a post-nuke horse-and-buggy age.
510* ''Webcomic/UnOrdinary'': High school with superpowered students, with a normal main character
511* ''Webcomic/TheUnthinkableHybrid'': A 50s based multi-issue story about a TheSmartGuy Prof, a {{Monster}} and a trio of kids.
512* ''Webcomic/UtopiaNext'': Set in 2118, the story follows a government investigator named Dawn as she deals with some very real problems in a world that most think will soon be perfect.
513* ''[[http://www.utopiatescomic.com Utopiates]]'': In the near future, science is able to distill human personalities into a drug-form. Called utopiates (a merging of the words 'utopia' and 'opiate'), these drugs allow users to swap personalities with the "mental imprints" of other people. Every user has their own reasons for seeking chemical escape, but all soon learn the cost of soul swapping is extremely high. From the creator of ''[[http://www.titaniumrain.net Titanium Rain]]''.
514* ''Webcomic/ValAndIsaac'': ScienceFantasy space mercenary SliceOfLife comic. [[CastFullOfGay Nearly everyone's gay.]]
515* ''Webcomic/ValkyrieSquadron'' [[http://www.valkyriesquadron.com]]: Humanity is at war with the droids, and things are looking grim. In the spirit of Battlestar Galactica and Bubblegum Crisis, follow a squadron of four, female warriors and the part that they play in this exciting futuristic war epic. from the creator of [[http://www.marsh-rocket.com Marsh Rocket]].
516* ''Webcomic/{{Vanguard}}'': A British superhero webcomic where things only seem to get worse. Primarily follows the adventures of the government controlled British superteam, the Vanguard. Made by Dan Butcher.
517* ''Webcomic/{{Vexxarr}}'': An incompentent alien conqueror and his misfit crew, on their neverending quest to find some place in the universe where they won't get killed.
518* ''Webcomic/TheVolet'' combines sci-fi and fantasy elements, quite expected when you mix ''VideoGame/ChronoTrigger'', ''VideoGame/FinalFantasyVI'' and ''Franchise/StarWars''.
519* ''Webcomic/VortoThePirate'': Two-fisted adventure on the high seas of space. Emile Vorto, the notorious space-pirate, and his companions battle the empire which has enslaved him. Vorto duels the pilots of the deadly Scorpio Squadron to win his freedom and that of the peoples of Orgom.
520* ''Webcomic/WanderingOnes'': Most of the human population of earth was wiped out by a viral weapon; 30 years later, several factions are attempting to restore order to the world, some more violently than others. This is the story from the perspective of the Clan of the Hawk, a naturalist group of survivalists and trackers.
521* ''Webcomic/WanderersOfTheCosmos'': A SpaceOpera in which a FiveManBand gets wrapped up in an ancient conspiracy.
522* ''Webcomic/WarbotInAccounting'': ExactlyWhatItSaysOnTheTin. A decommissioned military robot must try to get along at a desk job in an accounting firm. It's not a comic for the easily depressed.
523* ''Webcomic/WastedAway'': A group of cats try to survive after a massive human war.
524* ''Webcomic/WastelandersAnonymous'': Takes place after some event has destroyed most life on Earth.
525* ''Webcomic/WaywardSons'': The story of the [[HumanAliens human-like]] crews of two starship from a distant galaxy who crash-landed on Bronze-Age Earth after traveling through another dimension and gaining superpowers in the process. Their presence and conflicts at the dawn of human civilization give rise to many of the ancient mythologies and legends. SugarWiki/NeedsMoreLove and a page of its own!
526* ''Webcomic/WeaponBrown'': ''ComicStrip/{{Peanuts}}'' meets ''Film/MadMax'', with [[LawyerFriendlyCameo Chuck]] "Weapon" Brown, a cybernetic gun for hire, running around the wasteland as he unwittingly carries around the MacGuffin -- a thermos full of genetically enhanced breast milk. Just as awesome as it sounds.
527* ''Webcomic/WeAreTheWyrecats'': A team of special-needs students tries to make the world a better place through their ideals and advanced PoweredArmor technology. It doesn't go well.
528* ''Webcomic/{{Westward}}'': Set in an [[AlternateHistory alternate 1999]], this is a SpaceOpera about a group of colonists voyaging on humanity's first [[FasterThanLightTravel faster-than-light]] starship, the mysterious Martian scientist who guides them, and an IntrepidReporter who may just uncover a mystery of truly cosmic proportions -- if he can come to terms with the ghosts of his own past...
529* ''Webcomic/{{White Noise|MelindaTimpone}}'': A genetically engineered teenager must survive to find out the truth about himself in a post-apocalyptic future.
530* ''Webcomic/WickedAwesomeAdventure'': Four heroes survive a Darwinian Apocalypse and awake to a very peculiar world. This comic also functions as a text-based adventure game for its readers.
531* ''Webcomic/{{Wootlabs}}'': About a semi-reformed SuperVillain "family" (A MadScientist, her two robot and one humanoid lizard girl creations, a super-powered penguin and the scientist's ActionGirl hero girlfriend).
532* ''Webcomic/XComFirstToFight'' [[http://xcomftf.smackjeeves.com/]]: "Humans and Aliens face off in a conflict where the stakes are nothing less than the future of humanity itself."
533* ''Webcomic/{{Xenospora}}'': A webcomic that tells us about the political strife between humans and an alien race known as the Prac.
534* ''Webcomic/XkcdTime'': A subcomic of ''Webcomic/{{xkcd}}'' where a sandcastle-building boy and girl set out to find out why the sea is rising.
535* ''Webcomic/{{XRS}}'' A military sci-fi webcomic about a deadly new super-weapon.
536* ''Webcomic/{{Yosh}}'': A wacky comic that somehow mixes penguins, [[CatGirl cat girls]], [[RobotGirl robot girls]], magic, and anime jokes into a coherent story about finding acceptance and love in a world full of everything mentioned above.
537* ''Webcomic/TheYoungProtectors''
538* ''Webcomic/ZackAndZeke'' [[http://www.zackandzeke.net/]]: An alien struggles to research the human race p close while keeping his sanity. Unfortunately, his only human friend is an absolutely moronic boy, not to mention he's constantly in danger of being captured by Jack, the merciless (albeit not very good) alien hunter.
539* ''Webcomic/{{Zap}}'' (Finished): A amnesiac psychic finds himself the captain of a special ship in LaResistance. He bumbles along until his past catches up with him.
540* ''Webcomic/ZitaTheSpacegirl''
541* ''Webcomic/TheZombieHunters'': A [[TwentyMinutesIntoTheFuture near-future]] [[AfterTheEnd Post]]-[[ZombieApocalypse Zombie Apocalyptic]] story that follows a [[RagtagBunchOfMisfits motley crew]] of DisasterScavengers training in NewMeat and trying not to get eaten on the job, as what's left of [[EndangeredSpecies humanity]] and [[PoliceState government]] fights to survive, [[FightingForAHomeland recover from]] and FindTheCure for TheVirus that [[DepopulationBomb devastated]] the globe and created a [[EverythingIsTryingToKillYou world of monsters]].
542* ''Webcomic/ZombieRanch'': A [[BlackComedy darkly comic]] look at a future U.S.A. where the West is Wild again in the wake of a [[ZombieApocalypse Great Zombie Plague]], and a reality television show is following the day-to-day tribulations of a young rancher and her crew as they wrangle herds of dangerous undead for profit.
543* ''Webcomic/{{Zortic}}'': A burger-flipping college-student alien and his friends explore the universe, one Earth pop-culture parody at a time.
544* ''Webcomic/{{Zukahnaut}}'': A foul-mouthed alien with an overactive imagination takes up residence on Earth and gets into all kinds of strange trouble.
545[[/index]]

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