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9->''"Your head will swell up like a watermelon... You'll gain about 100 pounds in 2 hours... You'll grow claws. Big ones. Then you notice six huge hairy tits swollen up on your back... you go blind... your body will turn to wax... they'll have to put you in a wheelbarrow... and when you squeal for help, you'll sound like a raccoon."''
10-->-- ''Literature/FearAndLoathingInLasVegas'' (TheFilmOfTheBook) on what supposedly happens if you eat a pineal gland
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12Because the human pineal gland is buried deep in the fleshy bits of the brain and was the last part of the endocrine system to be understood, it's picked up a bunch of mystical baggage. It's often associated with {{telepathy}} and/or enlightenment; sometimes it's referred to as a "ThirdEye". To be fair, Website/TheOtherWiki does say that in nonmammal vertebrates the [[http://en.wikipedia.org/wiki/Pineal_gland pineal gland has cells similar to those in the retina]]. In some reptiles, fish, and amphibians, it even [[http://en.wikipedia.org/wiki/Parietal_eye connects to an external opening and has light-sensing properties]] (which serve to regulate physiological day/night cycles rather than to perceive).
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14The pituitary gland can also be used in a similar way, possibly because writers don't know the difference. Another option is the adrenal gland, especially as UrbanLegends claim that the psychoactive compound [[https://en.wikipedia.org/wiki/Adrenochrome adrenochrome]] can be obtained only via adrenal glands extracted from a living victim (a myth that seems to have originated in Creator/HunterSThompson's ''Literature/FearAndLoathingInLasVegas''). Even cerebrospinal fluid is sometimes treated as a liquid equivalent, thanks to the vampiric implications and the chance to have victims of CSF-theft actually survive their loss.
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16Often this runs in tandem with NinetyPercentOfYourBrain. The {{Trope Maker|s}} is none other than Rene Descartes, who believed that the pineal gland was the "seat of the soul", and the connection point between mind and body. He wasn't the only one, as both [[ScienceMarchesOn scientists]] and occultists were quite enthusiastic about the idea for a while.
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18Today, scientists like [[http://en.wikipedia.org/wiki/Rick_Strassman Rick Strassman]] theorize that the dimethyltryptamine naturally present in the human body [[http://en.wikipedia.org/wiki/Dimethyltryptamine#Speculation may originate from the pineal gland]] and could be responsible for dreaming.
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20The human pineal gland's accepted function, by the way, is to produce melatonin, a hormone that helps to regulate sleeping patterns, plus a tiny amount of antioxidant. Mess with the thing, and the most you'll get as a result is insomnia, not ESP.
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22----
23!!Examples:
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25[[foldercontrol]]
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27[[folder:Anime and Manga]]
28* In ''Anime/BubblegumCrisis 2040'', Dr. Stingray's Boomer technology is ultimately based on a reproduction of his wife's pineal gland implanted into his daughter Sylia's brain to grow into the first Boomer cores. [[spoiler:The Knight Sabers' hardsuits are derived from the same basic technology, which greatly restricts who can use them successfully. In addition, the implant resonates with prototype unit Galatea to give all three Knight Sabers visions of Sylia's past.]]
29* ''Manga/ElfenLied'': The Diclonii start their lives as humans with a huge pineal gland. If their psychic "Vector" arms come in contact with a normal human's pineal gland, that human will only create Diclonii when they reproduce.
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32[[folder:Comic Books]]
33* ''ComicBook/{{Superman}}'':
34** One [[UsefulNotes/TheSilverAgeOfComicBooks Silver Age]] comic has Superman exposed to radiation that causes his pineal gland to develop into a literal third eye, which allows him to defeat the villain.
35** ''ComicBook/SupergirlsGreatestChallenge'' has ComicBook/{{Supergirl}} visiting the future in response to a call for help from the ComicBook/LegionOfSuperHeroes. To get her up to date on the pending crisis, they use a future-tech device to download the info into her "'Third Eye' pineal gland".
36* ''ComicBook/TopTen'': One alien's diet is based on the chemicals secreted by the pineal gland, requiring a round of brain eating once a year. Police initially think it's just a calendar-themed serial killer. This assumption is helped by the fact [[DisposableSexWorker all the past victims are prostitutes]].
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39[[folder:Films -- Live-Action]]
40* ''Film/TheAlligatorPeople'': Secretions from alligator pituitary glands cause rapid regeneration that repairs injured humans' wounds, only to cause them to sprout scales within a year of treatment.
41* ''Film/FromBeyond'': The mad scientist stimulates his pineal gland, allowing him to see into other dimensions. Freshly put to use, it grows to the extent that it pops out of his head on a stalk. To the further amusement of anyone familiar with brain anatomy, as the stalk extends in front, yet the pineal gland is near the ''back'' of the human brain.
42* In ''Film/TheLeechWoman'', the juice from the pineal gland combined with a certain type of pollen forms an effective (but temporary) FountainOfYouth.
43* In ''Film/Plan9FromOuterSpace'', stimulating the pineal and pituitary glands of corpses turns them into zombies.
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46[[folder:Literature]]
47* In ''Literature/ArtemisFowl and The Opal Deception''Opal Koboi has a human pituitary gland grafted to her brain, not for any supernatural purpose, but so that the growth hormone it produces will cause her to gradually grow larger, in order to pass off as a human (at the time of the story, she is pretending to be a child). It also has the unintentional side effect of draining her magic for some reason, though she is unaware of it until she finally runs out at the worst possible time.
48* This plays a role in the 1949 science fiction novel ''The Brain'', about a city-sized MasterComputer built in the shape of the human brain (down to its internal anatomy). Since the pineal gland is associated with "unscientific" topics (such as ESP and soul), the Brain's builders are not interested in the section corresponding to the pineal gland and repurpose it as a control central. [[spoiler:However, when someone inadvertently sets up a feedback loop in the "pineal gland", the computer becomes self-aware and [[GrewBeyondItsProgramming outgrows its assigned tasks]].]]
49* In ''Literature/TheCompanyNovels'', the artificial hormone that makes cyborgs TheAgeless is called "Pineal Tribrantine 3".
50* ''The Dark World'' by Creator/HenryKuttner takes a ClarkesThirdLaw approach to magic. It doesn't really exist and mages are actually psychic mutants who get their powers from NinetyPercentOfYourBrain and "the ancient third eye that is the pineal gland".
51* In ''Literature/FearAndLoathingInLasVegas'', the protagonists convince a police officer that there's a plot to kill suburbanites for their pineal glands. This later turns out to be true (sort of). The story also originated related myths about the ''adrenal'' gland, namely that the purported hallucinogen adrenochrome can only be found in adrenal glands extracted from living victims. In RealLife, adrenochrome's supposed psychoactive properties are wildly exaggerated, and it can be easily obtained or synthesized without any murder necessary.
52* In ''Literature/{{Firestarter}}'', one of these glands is a seat to Charlie [=McGee=]'s power.
53* In "Literature/FromBeyond", a MadScientist creates a machine which stimulates the pineal gland, allowing humans to see ''really clearly''. Apparently, "fresh air" and "blue sky" are made out of amoeba-like monstrosities, and some unspeakable, unseen things stalk other lifeforms, and consume them into nothingness in seconds. This is the main risk for humans who open their eyes into this true reality, because what's actually going on is that they're seeing into normally invisible dimensions that intersect with ours. The danger is that people who gain the ability to see into those dimensions also become visible to the things that live there.
54* ''Literature/FutureTimesThree'' treats the matter slightly more realistically than most examples. In the far future, a subspecies of humanity that specializes in improved eyesight has three eyes on stalks. One of them is the pineal gland, which has (re)gained full functionality as a visual organ.
55* In one of the ''Literature/{{Lensman}}'' books, an alien doctor is able to make the (human) hero ''regenerate'' by stimulating his pineal gland.
56* In ''Literature/PrincipiaDiscordia'' (and thus also in ''Literature/{{Illuminatus}}''), the pineal gland is the organ that allows communication with Eris.
57* In the novel ''Return to Doomstar'', one of the planets visited by the protagonists has FunctionalMagic. In order to use it, the existing settlers compulsively cannibalize one another for their pineal glands, and attempt to do so to their guests. [[WouldHurtAChild The absence of children is conspicuously noted even before the reveal]].
58* In the science fiction short story "The Rose" by Charles L. Harness, the two protagonists (a ballerina/opera singer and a composer) "suffer" from an odd form of cancer: their pineal glands grow rather impressively, forming a pair of "horns" which curve around and over the brain before bursting out of the skull (but not skin) at the temples. They also get a kind of hunchback from a tumour that appears to contain brain tissue [[spoiler:(it does, and if the skin over it gets split, [[DoesThisRemindYouOfAnything it can engorge and tumesce from blood flow]], although this may kill the person in question)]]. They get a weird kind of projective telepathy apparently based on musical and colour theory, and spot patterns that no one else can see.
59* "The Stolen Body" by Creator/HGWells posits the pineal gland as a point of contact between embodied humans and the world of disembodied spirits.
60* In the ''Literature/VorkosiganSaga'' novel ''Ethan of Athos'', the Cetagandan Empire figures out how to bioengineer telepathy; their starting point is a homeless woman with a mutated pineal gland.
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63[[folder:Live-Action TV]]
64* In ''Series/AmericanGothic1995'', Lucas mentions the supposed importance of the pineal gland/third eye. Yancy then stabs him in the area in an attempt to kill him.
65* ''Series/CosmicDisclosure'': The Secret Space Program shocks employees to activate their pineal glands. For Corey, it was intended to increase his intuition powers. Even the whistleblowers don't really know what the pineal gland is for, but it's associated with astral projection and the light body.
66* In ''Series/Earth2'', the changes to Uly's system after his Terrian healing were suspected to have started in his pineal gland. Julia, his doctor, lied about it to protect him and the matter was quietly dropped.
67* ''Series/TheFlash2014'': Powers caused by the Central City MassSuperEmpoweringEvent are a result of dark matter in the pituitary gland. A cure is developed which neutralizes this dark matter and [[PowerNullifier can nullify the powers]].
68* In the ''Series/{{Fringe}}'' episode "[[Recap/FringeS01E02TheSameOldStory The Same Old Story]]", a serial killer is killing women and stealing their pituitary glands. [[MadScientist Walter Bishop]] deduces that it's related to a project he worked on for the government involving hyper-aging test-tube soldiers. The killer is one of the hyper-aging test subjects, and he's using the pituitary glands to maintain his age. Otherwise, he'd grow old and die really fast.
69* In ''Series/TheGirlFromTomorrow'', the pituitary gland has a telepathic function in humans.
70* Early fan theories posited that the pineal gland was the source of superpowers in ''Series/{{Heroes}}'', and to be what Sylar takes in order to absorb powers. Both of these are shown to be false in later seasons; powers are controlled by the adrenal glands, not the pineal. We also see the part of the brain Sylar interacts with, and it's nowhere near the pineal.
71* This trope is a RunningGag in ''Series/TheMiddleman'':
72** A minor character gets his pineal gland surgically removed and gains the ability to see and hear ghosts. [[ItsProbablyNothing He didn't see the surgery as worth mentioning when everyone was wondering how he was seeing ghosts]].
73** Another minor character has his pineal gland severed in a freak limbo accident and gains a telepathic link with his MirrorUniverse EvilTwin (who also had his pineal gland severed in a freak accident).
74** When the main characters encounter a flying fish that turns people into zombies, the antidote to the zombification is made from the fish's pineal fluid.
75** In the unproduced 13th episode, the villain's plan requires that he steal a number of pineal glands from people or creatures with mystical power.
76* ''Series/StargateSG1'' flirts with this trope in "[[Recap/StargateSG1S10E2Morpheus Morpheus]]", in which the danger-of-the-week is a parasite that puts people to sleep and then eventually kills them by causing aneurysms near their pineal gland. They eventually figure out that the parasite is feeding on melatonin -- which is what the pineal gland ''actually'' produces -- so in the end it's more an example of Pineal Normality.
77* An alien version occurs in the ''Series/StarTrekVoyager'' episode "[[Recap/StarTrekVoyagerS7E12Repentance Repentance]]", in which an alien psychopath was born with a detached equivalent of the pineal gland, leaving him prone to violent behavior. This changes when the Doctor treats him for head injuries sustained in a NoHoldsBarredBeatdown and accidentally reattaches the gland in question, triggering an immediate HeelFaceTurn.
78* In ''Series/TheXFiles'', the Black Cancer (or Oil), an alien life-form capable of taking control of its host, nests around the pineal body. It's mentioned briefly in "[[Recap/TheXFilesS04E09Terma Terma]]" but never elaborated upon. Interestingly, the most prominent place the Oil is shown to reside is in the eyes. Cue WildMassGuessing.
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81[[folder:Tabletop Games]]
82* In ''TabletopGame/{{Aberrant}}'', Novas draw their power from the Node, a part of their brain that grows in size when their power is awakened and grows further as they become more powerful. While no mention of it being the pineal gland has been made, it is implied to follow this rationale.
83* In ''TabletopGame/{{GURPS}}: Thaumatology'', one of the ways to draw on the [[MagiBabble hermetic decan of Alleborith]], associated with "pure" magic, is to use a pineal gland.
84* ''TabletopGame/MageTheAwakening'' has a [[PrestigeClass legacy]] in which on the first attainment the pineal gland fully develops into a black eye that pops out of the back of the Mage's skull. It enables them to have 360° vision, see the past and prophecy the future.
85* In ''TabletopGame/PrometheanTheCreated'', the pineal gland is the source of the {{ectoplasm}}ic humor that sustains the Ulgans. The pineal gland isn't actually special in humans, though -- in humans, the humors are metaphorical, not literal, and there's no such thing as an ectoplasmic humor, because the theory of humors was about physical and mental traits, not spiritual.
86* ''TabletopGame/VampireTheMasquerade'': In ''Clanbook: Malkavian'', there are a few references made to the pineal gland.
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89[[folder:Video Games]]
90* Averted in ''VisualNovel/Ever17'' when there's a brief discussion of the pineal gland and how it relates to the third eye, but it's dismissed as nonsense. They even [[ShownTheirWork mention Descartes' theories about it and the evolutionary history of it as a light-sensitive organ]].
91* In ''VideoGame/KingdomOfLoathing'', there used to be a quest where you had to [[TwentyBearAsses collect the pineal glands]] of zombies to make a vaccine. Zombie Pineal Glands still have a purpose: they're a small but essential component of a ''literal'' NinjaPirateZombieRobot. The event ended a ''long'' time ago, and for a good while, pineal glands were extremely expensive in the Mall. Eventually, the Item of the Month known as "the Deck of Every Card" gave players a way to fight zombies from the event, giving a new way for pineal glands to enter the Kingdom.
92* ''VideoGame/ResidentEvilGunSurvivor'' shows how Tyrants are made -- their key ingredient is a hormone secreted in the pineal gland of [[PoweredByAForsakenChild adolescent boys feeling extreme terror or stress]]. Umbrella's answer for harvesting such: remove the gland ''without anesthetic''. Needless to say, [[MoralEventHorizon it works]].
93* In the ''VideoGame/Postal2'' ExpansionPack ''Apocalypse Weekend'', when you go to the insane asylum, you find scrawlings within that detail plans to eat the inmates' pineal glands with a fork. These show up in several areas, so it's not quite clear whether the inmates, the staff, or both were planning on harvesting the inmates.
94* ''VideoGame/TeamFortress2'': In the Fancy vs. Nasty update, the [[PowerFist Fists of Steel]] description says:
95-->While boxing gloves were made to cushion your well-placed uppercuts, steel fists were made to beat the snot out of your enemies' pineal glands. "What are pineal glands?", you might ask! We at Mann Co have no idea ourselves, but what we do know is that these babies are made of freaking steel!
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98[[folder:Webcomics]]
99* In ''Webcomic/{{Spinnerette}}'', all SuperEmpowering [[MacGuffin Cherenkov-Kirby reactors]] are made from the pineal gland of Doctor Zhang, a.k.a. Ultra, the first superhero.
100* In the ''Webcomic/TeamFortress2'' comic "Old Wounds", Medic injects a whale's pineal gland into Sniper's brain stem, and dismisses Sniper's vision of [[spoiler:going to Heaven and meeting his adoptive parents again]] as a mere hallucination.
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103%%[[folder:Web Originals]]
104%%* Music/DoctorSteel's PSA, "Imagination."
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107[[folder:Western Animation]]
108* In the ''WesternAnimation/{{Futurama}}'' episode "[[Recap/FuturamaS6E18TheTipOfTheZoidberg The Tip of the Zoidberg]]", Dr. Zoidburg cures the Professor's "[[BigfootSasquatchAndYeti yetism]]" by transferring the pineal gland of a yeti into him, the explanation being that it produces a counter-toxin to the one in the yeti's claws.
109* ''WesternAnimation/TheVentureBros'': In "[[Recap/TheVentureBrosS1E5EenyMeenyMineyMagic Eeny Meeny Miney Magic]]", Dr. Venture's LotusEaterMachine "The Joy Can" operates by creating a direct link to the subject's pineal gland.
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