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1* This played a big role in the demise of the Creator/AlanMoore-helmed graphic novel ''Big Numbers'', with personal problems affecting each of the three creators attached leading to the project being abandoned after only two printed issues (out of an intended twelve):
2** Moore's polyamorous relationships with his first wife and their girlfriend fell apart during production, and as they ran the creator-controlled publishing company Moore was using for the book, he was forced to take the title elsewhere. Moore's exes subsequently folded the company and disappeared with a portion of his earnings.
3** The first artist, Bill Sienkiewicz, eager to test his creative boundaries, employed a time-consuming style that was heavily dependent on photo reference and acquaintances he used as non-professional models. The logistical nightmare of this method [[ScheduleSlip caused the second issue to be delayed]] and exhausted Sienkiewicz, who was going through his own marital problems. After completing the unpublished third issue, Sienkiewicz asked to leave the series.
4** The second artist, Al Columbia, was taken on solely because he was able to mimic Sienkiewicz's style. Columbia reportedly resented being made to copy another artist with no outlet for himself, leading to a poor work ethic. (He lied about his progress to his editors so he would [[OnlyInItForTheMoney keep receiving advance payments]].) The night before his deadline for the fourth issue, Columbia destroyed what few pages he completed, emptied his studio, and dropped off the radar for two years. Failure to find a new artist led to ''Big Numbers'' being cancelled.
5* ''ComicBook/CerebusTheAardvark'':
6** What happened to Dave Sim -- more than once -- while writing ''Cerebus'', mostly due to him going through a particularly unpleasant divorce at the time. With increasing frequency, [[AuthorFilibuster he would halt the plot in order to lecture at length]] about his new religion/theory-of-everything that he created from equal parts Old Testament, conspiracy theory and ''vast galloping misogyny''. Any characters or plot points that didn't fit his new view on life were hammered flat until they did, and Cerebus himself was made to come to the same religious revelations that Sim had, albeit filtered through his lowbrow, subtle-as-a-hand-grenade way of thinking. Note that this is unrelated to CerebusSyndrome, which occurred in the comic long before Sim's breakdown.
7** Sim's collaborator, Gerhard, also suffered this due to it getting more and more stressful to work on ''Cerebus''[[note]]due both to increasingly-tight deadlines and him no longer enjoying Sim's writing[[/note]] and to work with Sim. While his breakdown didn't affect the comic itself, it greatly affected his output ''afterward''; once he left Aardvark-Vanaheim, he couldn't bring himself to do any drawing for almost six years. Since then, he's dabbled in illustrating children's books and seems to have more-or-less recovered (although a cryptic line on his website mentions that some of the proceeds from his sales go towards his therapy bills).
8* Creator/GrantMorrison made a point of feeding their own personal life and interests into ''ComicBook/TheInvisibles'', including making a deformed villain based on the miscarriage that their girlfriend had. Weirdly, this also went ''the other way.'' Morrison is a magician and believed that in ''ComicBook/TheInvisibles'' they were creating a giant magical work that would reshape their life. Whether or not this is the case, there were some odd moments of synchronicity -- like the time their author insert character, King Mob, was shot in the chest, and Morrison was subsequently hospitalised with a collapsed lung.
9** Morrison is somewhat of a master of this trope, as they wrote about the death of their cat being used in their ground-breaking ''ComicBook/AnimalMan'' series. In issue 26, they note how as a creator, they simultaneously feel the pain and relish the opportunity to craft this into a story.
10** Morrison subsequently deliberately wallowed in negativity (resulting in at least one suicide attempt) in order to write the ''very'' dark comedy ''ComicBook/TheFilth''. Morrison saw it as a way of passing through the Kabbalistic abyss that represents the darkness at the depths of the human heart and mind, but they're like that.
11** Morrison also admitted that personal tragedies contributed to the very dark "Planet X" arc of ''ComicBook/NewXMen''.
12** ''ComicBook/AllStarSuperman'' was largely Morrison's way of dealing with their father's death. That theme also ran into ''ComicBook/SevenSoldiers'' and their Batman run. When it was pointed out that they didn't really touch on motherhood as much Morrison acknowledged that it might have largely to do with the fact that their mother is alive and perfectly healthy for the foreseeable future.
13*** [[HarsherInHindsight Their mother died in 2013,]] inspiring them to write ''ComicBook/WonderWomanEarthOne'', which focuses heavily on the main character's relationship with her mother.
14** One [[https://kierongillen.tumblr.com/post/52894563858/i-could-pull-quotes-from-this-all-day parody]] of Morrison joked on this, claiming that everything they write is to deal with either a dead cat or a bad breakup.
15--->'''Paul Gravett:''' Your ComicBook/FantasticFour miniseries? Cat or girlfriend?\
16'''Grant Morrison:''' Caring for a sick girlfriend.\
17'''Paul Gravett:''' Did she die?\
18'''Grant Morrison:''' No, she recovered. That’s why it’s only four issues.
19* James O'Barr created the comic ''ComicBook/TheCrow'' to deal with his grief over losing his fiancée Bethany, who was killed by a drunk driver.
20** It didn't work. That he became good friends with Brandon Lee during the filming of TheMovie turned what was intended to be cathartic release into an even greater source of grief to the point where he regretted ever writing it.
21* Creator/SteveDitko was the revered co-creator of the Franchise/MarvelUniverse among other creations. However, when he did not have a collaborator like Creator/StanLee to restrain him (or add his more humanistic viewpoint), his later stories tended to be barely more than self-righteous lectures about Objectivism.
22* When Creator/PeterDavid started writing ''ComicBook/TheIncredibleHulk'', he promised that he wouldn't kill off Betty Ross, Hulk's long-time love interest, partly because the character was one of his wife's favorites. Years later, he and his wife went through a painful divorce. Not long after ''that'', Betty Ross met a rather painful end in the comics. David has since come out and admitted that the strip was more than a little influenced by his real-life circumstances and, had things happened differently (not limited to the fact that he was soon taken off the book), he would have let Betty live.
23* Creator/GeoffJohns' sister died in the crash of TWA Flight 800. Surprisingly, nothing horrible happened to the character based on her, the Star-Spangled Kid (now known as Stargirl). However, the situation did inspire an influential arc of ''[[ComicBook/JusticeSocietyOfAmerica JSA]]'', in which Atom Smasher [[spoiler:loses his mother in an airplane crash, then substitutes the villain Extant -- who killed Al's godfather -- in place of his mother after a big reality-altering plot implodes]]. This led to the revitalization of Black Adam and the series' arguable high point, ''Black Reign''.
24* Mystek of the ''[[Franchise/JusticeLeagueOfAmerica Justice League Task Force]]'' was ThrownOutTheAirlock due to a tag-team combo of ExecutiveMeddling and the resulting breakdown. [[http://lamerciepark.com/legacy/comics/taskforce.html As writer Christopher Priest explains]]:
25-->We eventually introduced a character named Mystek, but I killed her off when her miniseries was not approved. Mystek was supposed to be a creator-owned character, developed under a first-look deal, and I was instructed to put her into ''JLTF'' to introduce her to the fans in preparation for her miniseries. Then there was no series, so I shoved her out an airlock in ''JLTF'' #32.
26* ''Adventures of Barry Ween'' creator Creator/JuddWinick wrote a touching graphic novel about his friendship with fellow ''MTV's Real World'' co-star Pedro Zamora and Pedro's eventual death, ''Pedro And Me''. Since then, much of Winick's work - particular at Creator/DCComics - has consisted of [[VerySpecialEpisode Very Special Issues]] involving HIV and homosexuality.
27** Winick also married his ''MTV's Real World'' co-star Pam Ling in 2001. Since then, he has also made an effort to introduce more minority characters in his comics and to utilize underrated minority heroes, particularly Asian females (such as Grace Choi). While this would normally be commendable, Winick's attempts at increasing diversity have been almost universally ham-fisted, with one of the most grievous examples being ''Green Lantern #150'', in which Kyle Rayner learns that his long-lost father is a Mexican immigrant... despite his father having an established history as being a deep-cover government agent who worked in Ireland and Kyle having already met his very-Caucasian uncle.
28* [[ComicBook/ChickTracts Jack Chick]] went through a breakdown that, for all intents and purposes, lasted till his death in 2016. He suffered a stroke in '96, and his ability to draw slowly deteriorated ever since.
29* Rob Schrab's difficult breakup and struggles with legal ownership of his characters as well as difficulties in getting his work adapted into other media combined to completely derail ''ComicBook/ScudTheDisposableAssassin'' towards the end of its initial run; the series starts out as a slightly surreal action comedy, but gets completely derailed near the end and concludes rather abruptly with the protagonist's girlfriend [[spoiler:butchered by sadistic angels, and a general theme of "there is no God."]] The 2008 series reboot is much less bitter and has a much more satisfying ending.
30* It can't be a coincidence that Creator/CarlBarks wrote ''Back to the Klondike'' -- the first allusion to a tragic romance in Scrooge [=McDuck's=] past -- right after [[http://www.cbarks.dk/thestorycommentariesfc0456.htm his divorce from his second wife]]. It would certainly explain his "[[WhatWereYouThinking What Was I Thinking?]]" reaction to the UnfortunateImplications he didn't even realize he'd implied until the censors pointed them out.
31* After the death of Creator/JephLoeb's son, Sam, there was a notable change in the theme and mood of Loeb's comics writing. He used one of his scripts and created "Sam story" comics for ''ComicBook/SupermanBatman'', and then retired from comics. Later his friends at Marvel convinced Loeb to return to the industry and work for Marvel. Since then Loeb wrote a mini-series about how several characters mourn Sam's death through the proxy that is ComicBook/CaptainAmerica, dropped a steaming load of controversial plot onto his ''ComicBook/{{Hulk|2008}}'' series, and tore through the [[ComicBook/UltimateMarvel Ultimate universe]] with Tomino-like reckless abandon. (It takes a Wikipedia page to list all of the characters that died in his ComicBook/{{Ultimatum}} limited series.) Losing a son is never easy...
32** He also gave the new ComicBook/{{Nova}} the name Sam Alexander in honor of his son.
33* Hergé wrote ''Recap/TintinTintinInTibet'' largely as a sort of therapy, to resolve the emotional issues he had following his divorce and the distressing dreams he'd been having that involved vast white landscapes. It is widely considered to be his masterpiece.
34** However, it caused Hergé to undergo ''another'' Creator Breakdown -- after the book was released, he decided that there was no way he would ever write such a good Tintin story again, and effectively gave up trying to do so. The remaining three Tintin stories were released at a far slower rate than the previous ones, and took the form of experimental character pieces which tended to mock the characters Hergé had been writing over the previous decades. ''Tintin and Alph-Art'' might have seen a return to the more traditional storyline, but we'll never know since Hergé sadly DiedDuringProduction with the story only half-finished.
35* James Robinson's controversial ''Franchise/JusticeLeagueOfAmerica'' run contains several instances showing the author's increasing frustration with the criticism of his work. The final issue notably expresses Robinson's annoyance at his run being cut short by the impending [[ComicBook/{{New 52}} DC reboot]] and contains a pointed TakeThat directed at the run's critics, with Batman stating he [[LeaningOnTheFourthWall didn't care if the public didn't embrace that iteration of the team]].
36** There's also a shot at relative newcomer [[ComicBook/BatmanGrantMorrison Batwing]] getting his own title while several of Robinson's characters were slated to be sent to ComicBookLimbo or {{retcon}}ed out of existence.
37* Everything [[http://en.wikipedia.org/wiki/Ivan_Brunetti Ivan Brunetti]] has ever written. It's a wonder that he's still alive and drawing.
38* Creator/JackKirby had this ''bad'' in the late 1960s. Oh sure, he was the King of Comics, and his [[UsefulNotes/TheSilverAgeOfComicBooks Silver Age]] Marvel stuff is considered some of the best comics ever, but he had a lot of personal issues on his plate. He was getting more and more flustered over his lack of creative control, he couldn't negotiate for a higher salary or even make sure that his family would be provided for if anything happened to him (nowadays this stuff is guaranteed in the industry), Stan Lee was getting all the good press, and he was terrified that he would lose his job if anybody found out that he was going blind in one of his eyes. Then came the 1969 ''ComicBook/SilverSurfer'' issue that lost him his crown.
39** Kirby was angry that Stan Lee got credit for the Surfer when the character was his own independent creation. He was angry when Lee began writing a ''ComicBook/SilverSurfer'' series and got somebody else to draw it. He was angry that Lee concocted an origin story for the Surfer that was completely different from his own idea. And ''then'' Lee asked Kirby to draw a ''fill-in issue'' for the book, and mentioned that this issue would change the Surfer from a philosophical pacifist to a berserk enemy of all mankind to help boost sales. Kirby gave Lee [[BeCarefulWhatYouWishFor exactly what he asked for.]] The highlight of the issue is supposed to be an epic battle between the Surfer and Black Bolt, but the Surfer gets pissed halfway through and just leaves. The penultimate page is uncharacteristically dark, especially for Kirby, as the Surfer sits and lets his rage take him over completely. The final page is [[http://marswillsendnomore.files.wordpress.com/2011/02/jack-kirby-silver-surfer-small.jpg a full-sized portrait of the Surfer's tormented face screaming in fury and declaring that soon the universe will fear his wrath]]. That's right -- Jack Kirby drew his own creator breakdown right into the Surfer's mouth, handed it over to his bosses, and jumped ship to DC Comics and [[ComicBook/NewGods other things]]. BewareTheNiceOnes indeed.
40*** Ironically, Lee pushed Kirby into doing his last great burst of creativity for Marvel with that last Silver Surfer. Kirby was pretty much marking time on the ComicBook/FantasticFour for his last twenty or so issues, deliberately keeping all his good ideas to himself so that he could do them over at DC without Lee.
41* Franquin's ''ComicBook/IdeesNoires'' (''[[ExactlyWhatItSaysOnTheTin Dark Thoughts]]'')
42** Franquin experienced in fact various depressions throughout his career, the first one being on the 60s, while the "Dark Toughts" part of his work happened in the 70s. In the early 60s, Franquin's break down affected his work on the "[[ComicBook/SpirouAndFantasio Spirou et Fantasio]]" saga, resulting in the unusually dark "QRN sur Bretzelburg" album. The album deals with themes such as War Trade and totalitarian states.
43* Lewis Trondheim treats of this issue in his essay ''Désoeuvré'' (''Loose End'') and mentions many comics authors.
44* Peter Laird sold ''Franchise/TeenageMutantNinjaTurtles'' to Viacom because he was distancing himself from his loved ones in order to oversee the franchise's development. Ironically enough, Kevin Eastman gave up his shares to Laird for the same reason nearly a decade before.
45* Creator/{{Dwayne McDuffie}}'s final ''[[Franchise/JusticeLeagueOfAmerica JLA]]'' arc was basically a metaphor for his then-deteriorating relationship with DC Comics. Near the end of the story, most of the League's members have quit (in real life most were taken away from Dwayne due to ExecutiveMeddling) and several other members, notably ComicBook/BlackCanary, begin to question their commitment to the team and whether or not they even care enough to continue protecting the world.
46** In later interviews for his ''WesternAnimation/JusticeLeagueCrisisOnTwoEarths'' movie, Dwayne would slyly mention that it was refreshing to get to write a Justice League story without having other people mucking up his work.
47* An interesting if entirely fictional variant came in the Superman one-shot 'Under A Yellow Sun'. After years of mentioning ComicBook/PostCrisis Clark Kent's career as a novelist, we actually see some, featuring a swashbuckling hero through whom Clark works out his other career's ups and downs. During a particularly bad patch in which his Sisyphean battle with the CorruptCorporateExecutive version of Lex Luthor is going not well at all, he has his character finally kill the bad guy, a choice for which Lois lambastes him. After reminding himself of some necessary truths about the never-ending-battle, he has the character do what he has always done, sparing and even saving the life of the worst person he knows. The irony comes when he receives praise for the novel from closet page-turner popcorn-reader Luthor.
48* Jamal Peppers, artist for the first four parts of ''ComicBook/SonicTheHedgehogMegaManWorldsCollide'' suffered a more literal one when he had to be hospitalized before he could finish the fourth issue. Another artist jumped in to finish it up.
49* In-universe in Creator/ScottMcCloud's comic ''[[http://www.scottmccloud.com/1-webcomics/mi/mi-15/mi-15.html Uninformed Bob]]'', which depicts a gag-a-day comic strip written by a cartoonist who slowly goes insane, [[spoiler:because he is dying of cancer]].
50* In-universe in ''ComicStrip/KnightsOfTheDinnerTable'': Jolly Blackburn wrote a "review" of the Gary Jackson TabletopGame/HackMaster novel ''The Lady is a Thief''. The protagonist was based on Gary's wife Heidi, and becomes evil and vicious for no good reason at the point of the novel that was written during Gary's divorce. According to the review, the book was pulled from publication after Heidi sued for defamation, and only a few stray copies remain in circulation.
51* Bill Jemas wrote a miniseries called ''ComicBook/{{Marville}}'' which began as a parody of comic books, then after two issues the series devolved into Jemas preaching his (completely nonsensical and almost universally factually wrong) philosophies of life, the universe, and everything. The series was widely critically panned even before jumping the shark and didn't sell well ''at all.'' The penultimate issue of the comic[[note]] the final issue of the comic was just a set of submission guidelines for Epic Comics [[/note]] has the main character retelling the entire story to a comic publisher -- with both agreeing that the story is ''the most important story that could ever be told'' -- but it isn't published because all audiences want in comics are superheroes. The entire issue reads like a diatribe against the comic's readers (or more likely; the lack thereof) for not understanding its genius. Jemas was convinced ''Marville'' didn't succeed because comics readers have no interest in non-superhero stories, and immediately after publishing the final issue Jemas revived the then-dormant Epic line of Marvel Comics.
52** ''Marville'' was Jemas' portion of a contest between he, Ron Zimmerman, and Peter David over which could write the better-selling comic series. Peter David's resulting Captain Marvel comic was a critically acclaimed success that went on for twenty-five issues. Jemas became so desperate to win the bet that the covers of issues 2-5 had a mostly naked well endowed woman on the cover, and Issue 6's cover featured Wolverine. ''Marville''[='=]s total jumping of the shark curiously started about the time that it would have become obvious that Jemas had lost the bet.
53* Creator/FrankMiller -- a fairly politically-driven creator who lived in New York City for most of his life -- was ''deeply'' affected by the terrorist attacks of September 11, 2001, and his shifted worldview was greatly seeped into his most controversial post-9/11 works, namely ''ComicBook/TheDarkKnightStrikesAgain'' (which features the decimation of a major city and the chaos that follows) and ''ComicBook/HolyTerror'' (an extended war against Islamic terrorists in light of a similar terror attack). He's mellowed out in the years since ([[CreatorBacklash coming to regret]] ''Holy Terror'' as being a bad, hateful story fuelled by a dark time where he "wasn't thinking clearly"), but even his newer works tend to be driven heavily around unstable progress following a post-9/11 world.
54* It's been suggested that Mark Millar has grown to loathe and despise the comic book industry in general, as well as himself for being a part of it. They cite the excessive and brutal violence against Millar's own characters and against comic book stores and comic readers in ''Film/KickAss2'' to support this theory.
55** His work in ''ComicBook/UltimateXMen'' had a bit of foreshadowing to this. The book always had a cynical edge to it (even moreso than Millar's concurrent work in ComicBook/TheUltimates, which at least had BlackComedy to blunt its sharp corners), but took a nosedive into [[CrapsackWorld [=GrimDark=]]] during the "Weapon X" story arc. To be fair, Millar was hospitalized for a debilitating illness and in chronic pain during his early tenure on the book, and he [[WordOfGod later admitted in an interview]] that he was probably projecting his own misery onto the characters.
56* In August of 2001, Creator/JoeQuesada and Nick Lowe successfully convinced Creator/NeilGaiman to create a miniseries for Marvel, though at the time, Gaiman had no idea what that miniseries would be. Less than a month later, September 11th happened, and a depressed Gaiman decided that he didn't want to write anything featuring planes, skyscrapers, guns, or bombs, and didn't want "a story in which might made right – or in which might made anything." In the end, what emerged was ''ComicBook/{{Marvel 1602}}'', which got a somewhat mixed reception.
57* Creator/GregRucka quit writing a ''ComicBook/{{Cyclops}}'' series after the death of his father. As he explained, he no longer felt able to write a story about time-displaced teenage Scott Summers bonding with his father in such circumstances.
58* Creator/TomKing is perhaps infamous for his tendency to inject very psychologically-driven plots in the characters he writes, with a SignatureStyle influenced by themes of [[ShellShockedVeteran dealing with or enduring trauma]], offbeat alienation from humanity, and topical politics. He's very open about the fact that [[WriteWhatYouKnow this is largely built off his own history of working for the CIA and the fallout of his time in Iraq]]. In a more condensed instance, he suffered a severe panic attack and worsening depression from sudden family deaths and political turmoil during 2016, in turn influencing a direction of not merely living through trauma and failure, but also trying to cope with or overcome it.
59* George Caragonne's tenure as editor of ''Penthouse Comix'' magazine was marred by behind-the-scenes turmoil, with Carragonne [[HighTurnoverRate firing writers on a whim]]; engaging in drugs, alcohol, and extramarital affairs; and fighting with foreign censors over the content of the magazine. He was also wildly overspending the budget, sometimes splurging on non-''Penthouse'' projects or expensive personal items, leading to the company accusing him of embezzlement. On July 14, 1995, Caragonne found himself locked out of the office and was told that ''Penthouse'' was conducting an audit on his expenses. Several days later, on July 20, he visited the Marriott Marquis Hotel in Times Square [[DrivenToSuicide and jumped from the top floor of the interior atrium, falling 500 feet to his death]]. ''Penthouse Comix'' would later fold in 1998.
60* This ''may'' have happened to Creator/WarrenEllis in the mid-1990's. During that time, he worked on ''ComicBook/Druid1995'', starring C-List member of ''ComicBook/TheAvengers'' Doctor Druid, apparently intending on mimicking another title, ''Hellstorm'', starring C-Lister character Daimon Hellstrom. However, sales were so abysmal that that ongoing series was turned into a four-issue mini-series, which ends Druid killed by a magical gun and burned in a dumpster by Hellstrom himself.
61* Martin Wagner's original self-published run on ''Hepcats'' was marred by a messy divorce, which proved irksome as one of its central characters was loosely based on his then-wife. A deal with Antarctic Press to reprint the series along with new material saw only two new issues reach print before Wagner abandoned the project again, which he later attributed to burnout. An attempt to relaunch ''Hepcats'' ten years later as a webcomic went nowhere, leading Wagner to throw in the towel and leave the comics industry for good.

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