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10[[quoteright:350:[[VideoGame/Fallout3 https://static.tvtropes.org/pmwiki/pub/images/centaur.png]]]]
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13!!Works with their own pages:
14[[index]]
15* ''BodyHorror/TheDCU''
16[[/index]]
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19* Dr. Miguele's abominations in ''VideoGame/TwoDark''. There are also the failed experiments preserved into jars in his lab.
20* The main plot of ''VideoGame/AgentUSA'' consists of fighting against an experiment with a TV set which had GoneHorriblyWrong and is now turning every citizen of the United States into mindless, walking TV static. The worst part is that this can happen to ''your character'', and instead of ending the game, you just wander aimlessly forever, having lost your mind and turned into fuzz.
21* Thought [[Film/{{Alien}} seeing the chestburster explode out of John Hurt's chest]] was bad enough? The second level of the Alien campaign in ''VideoGame/AliensVsPredator2'' starts out ''in the host's torso, with you as the chestburster.'' No prizes for guessing what you have to do.
22* ''VideoGame/AlterAILA Genesis'': [[spoiler:The prisoners near the core of Orbital Prison may or may have not been mutated by the Nightmare System. Trauma is the most notable example; he transforms into a plant-like being when he takes enough damage.]]
23* ''VideoGame/{{Amnesia}}'':
24** ''[[VideoGame/AmnesiaTheDarkDescent The Dark Descent]]'' has this in a lot of ways. For example, the Gatherers. Their bottom lips are stretched down and fused to their chest, turning their mouths into gaping maws that '''''never shut''''' -- and ''[[WasOnceAMan they used to be human]]''.
25** Taken further in ''[[VideoGame/AmnesiaAMachineForPigs A Machine For Pigs]]'' with the Wretches that populate the titular machine.
26* In ''VideoGame/AncientDomainsOfMystery'', the [[TheCorruption corrupting radiation]], slowly affecting the inhabitants of the world, causes several stages of mutations. These include ten extra eyes, gaining poisonous hands and the transformation of feet into hooves, just to name a few. These have an actual effect on gameplay. Becoming too corrupted will eventually dissolve you into a pile of pure Chaos. Fortunately, it's all text-based, but even the descriptions manage to be somewhat disturbing. With the addition of graphics in the new version, your character's appearance is still not altered, but you get to see what corrupted monsters like a [[http://ancardia.wikia.com/wiki/Chaos_warrior Chaos Warrior]] or [[http://ancardia.wikia.com/wiki/Chaos_mutant Chaos Mutant]] look like.
27* The Sauroid enemies in ''VideoGame/ArcRiseFantasia'' are all revealed to be humans in the midst of transforming into [[spoiler:feldragons]], the same creatures the protagonist spent his entire life slaying.
28* ''VideoGame/AwayJourneyToTheUnexpected'': The Labiworks Manager fell in the liquid the company's been mining recently, and the results are not pretty. His skin's turned red, his arm is turned into a vestigal nub, and the right side of his body is covered in tumorous growths.
29* ''VideoGame/BeaconPines'': When a character ends up splashed in [[MutagenicGoo toxic waste]], the results aren't pretty, even if they're less overtly gruesome than most examples. [[spoiler:In one branch, resident bully Iggy gets shoved and falls on his side into the stuff, and ends up with only the right half of his body [[RapidAging growing old and deformed]], with cataracts in his eye, his teeth sticking out, and one arm longer than the other.]]
30* The PlayerCharacter Audrey of ''VideoGame/BendyAndTheDarkRevival'' is slowly turning into an ink creature, starting with her hands.
31* ''VideoGame/BendyAndTheInkMachine'':
32** Basically every enemy is this, horrific fusions of human, ink, and cartoon. Some notable examples.
33** The Searchers and Lost Ones are both humanoid blobs of ink, but the former have no legs, and the latter are completely skeletal. Their leader, Sammy, is the most human-looking, with muscular-looking arms, but his face is blank with no eyes, mouth, or nose.
34** Norman Polk, AKA the Projectionist, has a projector for a head and film reels running through his body.
35** Susie Campbell, now Twisted Alice, has her name for a reason. Half her face is melted off and her halo is fused with her skull.
36** Charley has an eye sewn shut. He's missing a hand, and one of his feet is a plunger.
37** Barley's head is dangling from a fishing rod. He's also missing an eye and his eye patch is missing.
38** Edgar is supposed to be a spider, but his two left arms are both hooked up to the same prosthetic arm. The place where his mouth is supposed to be has been sewn shut and his mouth is on the top of his head instead. One of his eyes is a normal pie-cut cartoon eye, but the other is a human eyeball.
39* ''VideoGame/TheBindingOfIsaac''. Everything, including the protagonist Isaac, and the enemies he fights. The "power-ups" in this game are indeed power-ups, but they come with a serious price. Burning off one side of his face with toxic chemicals. Injecting himself with dubious substances. Live flies popping out of his body to attack his enemies. Growing giant twisted demon horns and firing a bloody laser beam from your mouth. All this... and Isaac has been confirmed by WordOfGod to be 5 years old...
40* ''VideoGame/BioShock'':
41** A trailer for ''VideoGame/BioShock1'' features the first-person protagonist in hand-to-hand combat with a Big Daddy Bouncer. He injects himself with an EVE plasmid into his arm, which causes the limb to apparently rot into a mass of suppurating sores, whereupon ''[[BeeBeeGun a swarm of bees]]'' crawls out of the holes in his arm while he screams bloody murder. And then it turns out this effect is in the game proper...
42** In addition to your hand becoming a living beehive with Insect Swarm, equipping other plasmids is just as disfiguring. For example, the FireIceLightning trinity of plasmids cause icy spikes to burst out of your hand (yes, with traces of blood), your hand to be covered with horrific burns and your veins to vividly glow with electrical energy, respectively. It's subtle, but if you look at the "pheromone" plasmids like Enrage, you can see your hand is covered in pus-filled blisters, implying the "squishy ball" is actually a clump of your own tissue.
43*** The disfiguring effects of Plasmids have become so iconic that they remain in ''VideoGame/BioShock2'' and ''VideoGame/BioShockInfinite'', despite the fact you play as a no-longer-human Big Daddy in the former and they're an entirely different gene-booster called Vigors in the latter.
44*** ''Infinite'' has a few very notable varieties of its own, especially since receiving a new Vigor prompts a brief cutscene in which you get a good look at some of its side-effects: for example, "[[PlayingWithFire Devil's Kiss]]" causes your hands to burn from the inside out -- right down to the bone; the idle animation to "[[CreepyCrows Murder of Crows]]" has your hand sprouting feathers and your fingernails growing into claws; "Bucking Bronco" shows bloody cracks forming in the skin of your hand, flesh dropping off in petrified clumps; "[[ShockAndAwe Shock Jockey]]" results in electricity-conducting crystals bursting out from under your skin; "[[DeflectorShields Return to Sender]]" slowly peels away the flesh of your hand and coats your finger bones in a black, metallic substance; even the comparatively benign "[[MakingASplash Undertow]]" sees pulsating octopus suckers and barnacles forming on your skin.
45*** Fortunately, all of these are temporary; your hand goes back to normal as soon as you put the plasmid away. The same cannot be said for the Splicers below.
46** Overuse of the miraculous gene tonics and "plasmids" that grant these special abilities leads to a different kind of body horror -- many of the Splicers encountered in Rapture are visibly deformed, in some cases featuring huge tumors growing out of their misshapen and twisted faces.
47*** Though the Splicers shown in-game are undeniably horrific -- the most notable being the [[http://bioshock.wikia.com/wiki/Crawler Crawler]] of ''VideoGame/BioShock2'' -- there are many Splicer designs that [[DummiedOut just didn't make the cut]], though they helped in getting ''[=BioShock=]'' made. There was Yam-Hand, a big, hulking, blue-collar type with one giant, potato-esque hand that he was forced to use almost like a club/cane/crutch, to the point where he stood like a gorilla. There was a man whose skin had begun to melt off of him, revealing various innards and bones. And there were various parasite-infested people, who weren't even people anymore. They had been taken over by insects, who had grown inside of them, and then, eventually, ''out'' of them. They were gigantic insects with various limbs, faces, and articles of clothing protruding from them. {{Squick}}, indeed.
48*** Along the lines of Splicers are Vigor Junkies from ''VideoGame/BioShockInfinite''. Although removed from the game they are later repurposed as Frosty Splicers. These Junkies/Splicers have mutated from excess Vigor/Plasmids and developed [[http://vignette4.wikia.nocookie.net/bioshock/images/c/c4/Afbioshockinfinite2013-5ecwp.jpg/revision/latest?cb=20140225102820 HUGE CRYSTALS ON THEIR ARMS AND HEADS]]. The original idea was that they mutated from using too much of the same Vigor and the character Cornelius Slate was supposed to be a mild Junkie, which is why he has those lumps on the right side of his head. Frosty Splicers eventually became this way from too much Old Man Winter plasmids turning them into old men with blue crystals and frost bitten skin.
49** There was one Big Daddy design that was "no fun to fight" that had CombatTentacles growing from its wrists and humeri.
50** The Big Daddy-fication process is beyond horrific (skin melted off, grafted into a diving suit, implanted with a voice box, mind wiped, etc.).
51* ''Videogame/{{Bloodborne}}'': The plague's specialty. If you're lucky, you'll just end up living deep in the UncannyValley. If you're not, well, say goodbye to actually looking like anything that ever resembled a human. The really bad cases tend to look like [[Myth/NorseMythology Fenrir's]] hypothetical children, complete with castle-wrecking size. The results are stated to be based on how much one resisted the plague before finally succumbing; normal people turn into human-sized werewolves. Church Hunters wind up as house-sized monsters known as Cleric Beasts.
52** A prevalent theme in the game is 'lining your brain with eyes' to gain Insight. Many enemy designs imply that this is meant to be taken ''[[EyesDoNotBelongThere completely literally]]''.
53** In-game, you fight two Cleric Beasts: a generic one and Vicar Amelia. Poor Amelia winds up a house-sized deer-wolf monstrosity in an incredibly PainfulTransformation (that thankfully is only shown in silhouette).
54** Basically anything wandering around in various Nightmares has this on some level. Loran Silverbeasts have their heads turned sidways, animals have mismatched limbs, the people of the Fishing Hamlet are what [[Literature/TheShadowOverInnsmouth Deep Ones]] wish they were, and the Byrgenwerth students trapped in the Nightmare Frontier have devolved into slimes.
55** The Healing Church has also created a whole lot of these, like the Living Failures and their half-melted heads, the Clocktower Patients whose heads have mutated into massive shapeless sacks of fluid (plus some so far gone they've ''become'' shapeless sacks of fluid), and the Brainsuckers, who have tentacles coming out of their heads and scars on their skulls that imply the Church put something in their brains.
56** Yahar'gul has a particular fondness for this trope, ''especially'' creating horrible monsters out of masses of corpses.
57** By far one of the most infamous examples is the fate of [[spoiler:Ludwig, the Holy Blade]]. He was once a fairly archtypical horseback KnightInShiningArmor, but the curse fused him with his horse into a gigantic, screeching mass of man and animal flesh, limbs, and features. The fact that during the boss fight, he TurnsRed by [[spoiler:regaining his human sanity and completely changing to act and fight like the sophisticated swordsman he once was, while still looking like a shambling mass of gore, is somehow even more wrong than a shrieking monster in the minds of plenty of players]].
58** Laurence, the First Vicar, is a cleric beast with ''lava'' for blood.
59* ''VideoGame/{{Borderlands}}'':
60** In ''VideoGame/Borderlands1'', the Badass Psycho has one tiny, almost vestigial left arm, and a heavily overdeveloped right arm. Here's a [[http://fc08.deviantart.net/fs70/f/2014/046/1/7/borderlands__badass_psycho_by_ogloc069-d76ksnt.png pic]].
61** The Badass Psycho reappears in ''VideoGame/Borderlands2'', and gains company. A relatively rare enemy called the Lab Rat has been driven insane by medical experiments, gaining glowing eyes from which it can [[EyeBeams shoot lasers]]. More commonly, bandit troops called Goliaths are always seen wearing some sort of headgear; if this is shot off, their face ''peels back over their skull, allowing their spine to elongate and thrust it clear out of their mouth''. A player can actually see their face wobbling around underneath the swaying, gore-coated skull as it scans for victims... not with any great ease, since the Goliath TurnsRed when this happens and goes berserk, drops his guns in favour of GoodOldFisticuffs, and starts beating the hell out of everything in sight, including his former buddies. A Goliath variant called the Caustic Goliath starts vomiting acid in this state as well.
62** In ''VideoGame/Borderlands2'', you can play as the mutant Kreig the Psycho. His Mania skill tree's Release The Beast is this. At critical health (33% or less) his inner voice can't hold back the anger and madness and [[http://vignette2.wikia.nocookie.net/borderlands/images/2/27/Krieg_Release_the_Beast.png/revision/latest?cb=20130527231443 The Beast]] is allowed to rampage, turning Krieg into a Badass Psycho. Like the other Badass Psychos, Kreig's right arm swells dramatically and his left arm shrivels to nothing. He screams with a deep, monstrous voice and attacks until the rampage ends.
63** One audio log in a side quest implies that not only are Goliaths aware of what happens after taking off their helmets, but they can somehow ''put them back on''.
64* In ''VideoGame/BreathOfFireDragonQuarter'', when you get your D-Counter to 100% and give up, a game over scene will play in which you get to see Ryu's silhouette on a red background getting brutally, mercilessly torn apart by Odjn [[ChestBurster bursting out of his body]], all while hearing Ryu's screams of agony. Pretty unusual for a JRPG to actually kill the main character, let alone in such a violent way.
65* One enemy type in ''VideoGame/BulletWitch'' is misleadingly called grubs. They're actually what happens when the ghosts Screamers spew possess a person -- a grotesquely distorted human with a bizarre, bloated head, that moves in a freakish way, and attacks you by biting you with its ribs and spewing fire.
66* ''VideoGame/{{Bugsnax}}'' shows a pretty kid-friendly version: anyone who eats the titular Bugsnax gets their body parts turned into food.
67* ''VideoGame/CaptainBlood'' is a videogame too old to evoke actual feelings of body horror, but the novella included in the manual, explaining the premise of the game, more than makes up for it. The main character of the game is a game programmer named Bob Morlock, who proceeds to create a space exploration game so realistic, it becomes real. Bob is teleported aboard the ''organic'' spaceship he created, where he is accidentally cloned 30 times after a hyperspace jump. The book then explains in detail how Bob's organs start shutting down because of the "vital fluid" he lost when he was cloned, and he needs to replace them by mechanical substitutes, gradually turning into a robot. But that is only a temporary remedy, because the goal of the game (stopping Bob's body degeneration) can only be achieved by killing all the other clones and absorbing their vital fluid.
68* ''VideoGame/CityOfHeroes'':
69** There is the Devouring Earth, creatures made of plants, stone, and flesh. Their goal is a world without humans. They achieve this by taking humans and mutating them into more Devouring Earth. During the Underground Incarnate trial, you get to see the Praetorian strain of the mutagen at work -- people (and robots) with bulbous blue tumors sticking off of them as they begin their transformation into Devoured, gigantic, tentacle-faced, claw-handed monstrosities that, at one point in the game's past, could summon Swarms (essentially, mutated bees) from a hole in their hands.
70** Earlier, there is a story arc devoted to helping a woman who has caught the amorous attention of the leader of the Devouring Earth, Hamidon (a four-story tall amoeba). A fair portion of the story arc involves keeping her away from the Devouring Earth to prevent them from infecting her. [[spoiler:The second-to-last mission is prefaced as a rescue mission, as the Devouring Earth broke into the safehouse where she was being kept. When you find her, she has already begun mutating into Terra, a Devouring Earth broodmother. The final mission has you capturing her, with unfortunately little hope of a cure.]]
71** There are also Arachnoids, creatures created by Lord Recluse through attempts to mimic his Incarnate powers on rank and file soldiers. They have varying levels of retained sentience, some being little more than mindless monsters, with many others still being intelligent enough to lament their fate.
72* ''VideoGame/CliveBarkersJericho'' is utterly rife with this. All of the monsters in this game were [[WasOnceAMAn once human]]: upon becoming [[spoiler:trapped in The Box/The Pyxis and succumbing to death, they are "assimilated" by the Firstborn. Upon returning to life]], they have transformed into grotesque parodies of their former selves. Some of the more extreme examples include Arnold Leach, who has transformed into a winged creature with ''his eyes being forcefully held open'' by what appears to be thick leather straps punching through his eyelids and scalp; the Crusaders, who have replaced several of their limbs with assorted weaponry and ''nailed'' their own armour to their flesh, and the Corpses Behomoths, who are essentially a ''[[TheWormThatWalks mass of human corpses held together by a collective mind]]'', formed into the shape of huge, crawling creatures, with a metal mask held onto their "faces" via strips of skin, through which they ''spit toxic corpse chunks''.
73* In ''VideoGame/CliveBarkersUndying'', Bethany got her final revenge on her brother Aaron by [[spoiler:chaining him inside her private dungeon and letting rats ''eat him alive'', removing his jawbone so he couldn't scream]]. This also qualifies as ArtisticLicenseBiology, since removing someone's jawbone does not affect his ability to scream -- the ''vocal cords'' should be removed for it. As a matter of fact, he could probably do ''nothing but scream''. Whether this makes it better or worse is probably not worth asking.
74* ''VideoGame/ClockTower1995'' has a severely deformed ten-year-old named Bobby, a mummified corpse you find in the trophy room, and [[spoiler:a huge, deformed, purple infant-looking thing who is the twin brother of Bobby]].
75* In the ''VideoGame/CommandAndConquerTiberianSeries'', this is what prolonged tiberium exposure has done at some points. It has gone from merely killing infantry, to turning them into [[http://images1.wikia.nocookie.net/__cb20090530124321/cnc/images/4/44/Visceroid_CC1_Art1.png huge moving aggressive meat-blobs]], to [[http://images2.wikia.nocookie.net/__cb20060811103006/cnc/images/thumb/8/8f/Tiberium_Infected_Human.jpg/281px-Tiberium_Infected_Human.jpg crystalizing them while they still live]].
76* ''VideoGame/{{Contra}}'' is no stranger to horrendous alien creatures, but ''VideoGame/ContraHardCorps'' goes for this in one route: [[spoiler:Colonel Bahamut ''injects himself'' with the Alien Cell, granting him immense power, but as the fight goes on it becomes clear the cell is taking over him, transforming him into a disturbing twin-headed beast (one head at each end), and then into a beating heart surrounded by spheres with screaming faces on them]].
77* ''VideoGame/CosmoPoliceGalivan'' has a boss called Hezmo, which is supposedly modeled after a Sumo wrestler... but made of entire lumps of oversized boils, tumors and pimples fused together into a humanoid body. The arena you fought him looks rather freaky as well, [[EyesDoNotBelongThere what with those eyes growing out of walls]]...
78* There's one {{Squick}}y moment in ''VideoGame/TheCrookedMan'' when you meet the title character and he twists his own neck before pursuing you.
79* Despite ''VideoGame/CrueltySquad'' being shown in crude, low-polygon graphics, it can still channel this effectively since you don't know ''for sure'' what the horrors you see are.
80** Many of the implants are pretty grotesque, including things like creating large holes in your heels to shoot out biological waste and gave you a mid-air boost, or partly lobotomizing yourself so you can jam a gun into your skull.
81** Quite a few of your targets are marked for death for fucking around with drugs, "biocurrency", or some other eldritch thing. Your first target in Pharmacokinetics is half-insane and has a visibly deformed skull -- the mission description also talks about him "vomiting blood all over his office". Later, in Androgen Assault, the Chief of Police, as a result of one too many experimental steroids from the Narcotics division, has turned into a fleshy bouncy castle-esque ''thing'' that spews corrosives at you.
82** Psykers and Fleshmen would look like "normal" humans, save for the fact their heads and faces have mutated into a horrific hive-like tumor.
83** Bioslaves. Even for how crude-looking humans are in the game, their faces are more ''off' than others. All they can do is walk around naked and scream endlessly. Killing them also causes them to burst into toxic gas.
84** You, potentially. If you're forced to undergo the "experimental regenerative treatment" after dying too much, you apparently turn into a faceless freak, if the other Cruelty Squad member you meet who underwent the same treatment says anything.
85** [[spoiler:The C3 DNA Scrambler takes the cake, as it's a gun that so utterly fouls up its target's DNA that they immediately turn into a mass of cancerous flesh.]]
86* Bosses in ''VideoGame/{{Cuphead}}'' regularly undergo all kinds of bizarre transformations and mutilations that would be far creepier if the game wasn't in the style of an old-timey Max Fleischer cartoon. The knockouts can be freaky too.
87* ''VideoGame/DarkSoulsI'':
88** The Egg-burdened. These poor guys have giant eggs growing out of their backs that are so heavy and huge that they can't even walk and are reduced to crawling. Despite this, most of them actually don't mind their situation seeing it as proof of their devotion to the mutated Daughters of Chaos. Many of them also carry Egg Vermifuges which can cure their condition -- it's entirely their choice. If you make one hostile, it will attack you and plant an egg in your neck that will eventually cover your entire head. It makes you less resistant to fire and halves your soul gain... but if you feed it enough souls, your kick attack will be replaced with a bite attack similar to the Egg-burdened. It's actually ''in your best interest'' to do this at least once, since the Egg-burdened NPC Eingyi will interpret your condition as a sign of devotion to the Fair Lady. He will then offer you an Egg Vermifuge and sell you the forbidden Pyromancies that the other Pyromancers exiled him for creating. On the same note, the Daughters of Chaos they worship, the Fair Lady and her sister Quelaag are human-looking women fused at the waist into giant, fire-breathing spider monsters, the Fair Lady looking very withered and sickly on top of it from trying to SuckOutThePoison for the Egg-burdened. Even they got off better than two of their sisters, who appear to have been transformed into inanimate root-like organs on the sides of the Bed of Chaos.
89** Ceaseless Discharge was originally a boy [[spoiler:and the aforementioned Daughters of Chaos' only brother]] born with a condition that covered his body in sores that constantly bled lava. After he loses a special ring that was made to keep his condition in check, he mutates into an enormous lava golem with fiery tentacles sprouting from his back and whose skin has bled so much he's turned the cave he's in into a LethalLavaLand.
90** The Gaping Dragon was once a dragon, but was constantly so hungry that its body mutated by splitting its head and neck down the middle to form a bigger mouth and forcing its ribs up and out to form more teeth.
91* In ''VideoGame/DarkSoulsIII: The Ringed City'', the Demon in Pain is differentiated from its partner in battle, the Demon from Below, by its ruined face and chest. If [[spoiler:it becomes the Demon Prince]], its deformities are even ''more'' pronounced.
92* ''VideoGame/DarkestDungeon'' has basically everything in the Warrens, half the things in the Weald, and any Cultist enemy you encounter in the Darkest Dungeon itself. In the Warrens, twisted experiments involving summoning and pig corpses have given rise to horrible misshapen creatures, including a boss that's a seething, mutated mass of pig flesh covered in eyes and organs that are supposed to be internal. In the Weald, human corpses covered in fungi scuttle around in disconcerting poses. And in the Darkest Dungeon itself, you get to see what the gifts of the new god look like, and they are ''not'' pretty; one enemy, the Priest, has been mutated so heavily they no longer even qualify for the Human type and appear to be mostly just tentacles hidden under a robe.
93* In ''VideoGame/DawnOfMana'', the unleashing of the Echoes from the [[WorldTree Mana Tree]] turns everyone into "Grimslies", and in addition to getting some really weird-looking face-vine...things, they're DrunkOnTheDarkSide and quite [[EverythingTryingToKillYou bloodthirsty]].
94* The Necromorphs of ''Franchise/DeadSpace'' are alien parasites that infect dead bodies. The infected corpses reanimate and start growing all sorts of disgusting appendages to kill the player with, such as bone claws and tentacles.
95** But among them, the Guardians and Dividers fit into this trope the most.
96** The Bosses should be also noted. They are [[BodyOfBodies fused from many human corpses!]] Needles to say this corpses are clerly distinctive. Hell, even some kinds of basic Slashers seems to be made from two fused humans.
97** For an added extra dosage of sheer WTF: [[ChurchOfHappyology Unitology]] ''worships'' these things! Their whole religion is deifying the instruction manual that humans used to create the Necromorphs in the first place ([[spoiler:the Black Marker was an alien artifact, but humans decoded the information on it and, in a ''Film/{{Species}}'' fashion, the genetic code for the Necromorphs was amongst that info, while the Red Marker was also made by humans using reverse-engineering of the Black Marker]]), treating being turned into a Necromorph as the key to becoming a "divine, immortal being". Needless to say, many of the more sane Unitologists started having doubts about their beliefs when actually confronted with the reality of the Necromorphs.
98** [[spoiler:The Brethren Moons are worse in concept than any Necromorph before them, being the final stage of the Necromorph "lifecycle". They are created during the Convergence event. As the name suggests, they are the size of a moon, made by the ''millions upon millions of corpses'' fusing together into one giant corpse planet.]]
99** Bonus points goes to the fact that during the development of the necromorphs, the dev team had a "horror" binder full of victims of car-crashes, bear attacks and various other unpleasantries.
100* The [[http://demigod.wikia.com/wiki/Unclean_Beast Unclean Beast]] of ''VideoGame/{{Demigod}}''. Grotesque as it looks, you also have to remember that this...'''thing'''...grew inside a human womb. An ordinary woman had to carry and give birth to this, completely ignorant as to what was growing inside of her.
101* In ''VideoGame/{{DONTLOOKAWAY}}'', if the Entity manages to touch one of the humans, the player is treated a horrifying cutscene as the character's limbs contort and break in a way that quickly kills them.
102* ''Franchise/DragonAge'':
103** ''VideoGame/DragonAgeOrigins'' features something like this with the abominations. While the player isn't given a chance to witness the transformation due to a glow effect, the way demons take over mages in the game universe results in a rather gruesome version of a human (or elf).
104*** [[AlwaysChaoticEvil Darkspawn]] in general qualifies as this [[spoiler:once you learn that they were the various races that populate Thedas, only mutated beyond recognition by the Darkspawn taint. The well-rounded hurlocks were humans, the numerous genlocks were dwarves, the stealthy shrieks were elves [[SuperpowerLottery and the massive ogres were qunari]]]].
105*** Worse yet is the [[spoiler:Broodmother boss fight later, which lets the player know before fighting it that the gigantic horrific boss was once a dwarf woman. This transformation is given as the explicit purpose for which the darkspawn even abduct mortal women rather than killing every last of them]].
106*** The Children. Take a worm, give it the face of a baby and we have these monsters. And this is just their first form.
107** In the finale of ''VideoGame/DragonAgeII'', [[spoiler:First Enchanter Orsino snaps after seeing so many of his fellow mages slaughtered by the Templars]]. Having crossed the DespairEventHorizon and wishing for nothing but revenge, [[spoiler:he sacrifices his principles and his humanity (technically he's an elf but still) by using BloodMagic to merge with the corpses of the fallen mages to become a Harvester flesh golem]].
108** ''VideoGame/DragonAgeInquisition'' adds Red Lyrium to the mix, which mutates the people it infects in grotesque ways. These mutations range from red eyes and distorted voices to having red lyrium protruding from their bodies like spines to becoming a raging behemoth barely recognizable as having once been human. Eventually the infected will transform entirely into red lyrium, inevitably killing them in the process. [[spoiler:Not surprising, since Red Lyrium is Lyrium tainted by the ''Blight''.]]
109** The Magisters Sidereal. [[spoiler:Former Tevinter magisters mutated by the Bligth, they had their clothes fused with their flesh. The Architect, in particular, had his eyes in places they don't belong.]]
110* In ''VideoGame/Drakengard3'', [[spoiler:[[GenkiGirl Two]] found out that using her [[MagicMusic song powers]], to heal the orphans she had been caring for, inflicted this on them. Turning them into a giant monster that still [[NightmareFuel cries out for her with their voices]]. She]] performs a MercyKill, but [[BreakTheCutie the results aren't pretty]].
111* ''VideoGame/DwarfFortress'': The most prominent example would be the [[http://www.bay12forums.com/smf/index.php?topic=70899.0 Kitten Rot]], one of the many possible Forgotten Beast syndrome. As the name implies, it causes the skin of the infected to completely rot off, leaving behind a horrible mass of living miasma. In its most basic form. If your medical staff is skilled enough, the afflicted may actually ''survive having their entire skin rotted off''. VideoGame/DwarfFortress players being [[VideogameCrueltyPotential Dwarf Fortress players]], this has been weaponised. Forgotten beast that rots the nervous systems of your dwarves, leaving them completely numb? Well, looks like you've just got a way to make your military immune to pain! (Also, dwarves without eyes are said to make excellent siege operators, since they don't run away from enemies even though they're civilians.)
112* ''VideoGame/{{Dreamkiller}}'' have ''all'' it's humanoid enemies, where they're either a deformed mess of limbs, arms fused into their midsections, grafted with assorted machinery, or tentacles emerging from various orifices, you name it. The whole game runs on PrimalFear, after all.
113* ''VideoGame/EldenRing'', being another From Software game, does ''not'' disappoint with the BodyHorror.
114** The first instance you'll come across is Grafting; the art of fusing severed body parts to one's own. Logical placement of said body parts not required. The first enemy encountered is the Grafted Scion, a young boy grafted so much he barely looks human (to the point his internal name is 'Graft Spider').[[https://www.youtube.com/watch?v=B_RkJJMwfCA This video]] goes into more detail about what the Grafted Scion looks like. And the boss Godrick the Grafted is even worse, with arms poking out all over his body, and most of his limbs being entwined masses of ''other'' limbs.
115** The Frenzied Flame drives people insane and causes their eyes to catch fire.
116** Scarlet Rot does this to anyone afflicted. Malenia, who's been cursed with it since birth, has her eyesight, three limbs, and her private parts simply rotted away.
117** Omens are massive beings with horns sprouting anywhere on their bodies. The Omen Mohg even has one of these horns ''growing into his eye''. Eeyow.
118** Rykard, Lord of Blasphemy, is what happens when you fuse this trope with SnakesAreSinister. He's a giant snake with a human(ish) face on his throat, two bloated human arms placed seemingly at random on his body, and gashes in his body that expose writhing limbs belonging to people he ''ate''.
119** [[spoiler:Radagon of the Golden Order has half of his body just crumbled away like he was a hollow ceramic statue, exposing the Elden Ring in his chest.]]
120* ''Franchise/TheElderScrolls'':
121** ''[[VideoGame/TheElderScrollsIIIMorrowind Morrowind]]'' has the horribly disfiguring [[ViralTransformation disease]] known as Corprus. Take a look at [[http://www.uesp.net/wiki/Morrowind:Ash_Creatures these things]] and remember that all of them used to be people. The disease was engineered by the DeityOfHumanOrigin BigBad (who has an EldritchAbomination slant) using the power from the [[CosmicKeystone heart]] of a [[GodIsDead "dead" god]].
122** In the backstory, the [[OurDwarvesAreDifferent Dwemer]] took in their [[OurElvesAreDifferent Falmer (Snow Elf)]] cousins when the latter were threatened by the invading [[HornyVikings Nords]]. The Dwemer [[EnslavedElves enslaved]] and mutated the Falmer from from [[http://en.uesp.net/wiki/File:SR-npc-Knight-Paladin_Gelebor.jpg this]] to ''[[http://en.uesp.net/wiki/File:SR-creature-Falmer.jpg this]]''; the Falmer now possessing claws, fangs, nostril slits instead of noses, and have skin grown over their blind eyes. This form of Falmer are a common mook in ''[[VideoGame/TheElderScrollsVSkyrim Skyrim]]''.
123** Namira is the [[OurGodsAreDifferent Daedric Prince]] of the [[DarkIsNotEvil Ancient Darkness]], associated with [[NightmareFetishist all things revolting]], [[NatureIsNotNice decay]], and [[ImAHumanitarian cannibalism]]. Suffering from some form of body horror is practically a requirement of her followers. Disfiguring diseases are her favored form of this. She has been known to outright refuse the worship of any who are not repulsive enough.
124* Disney's ''VideoGame/EpicMickey'' involves Mickey himself having parts of him melt and drip...''upward''. Plus the ability to use paint thinner to dissolve your enemies and melt [=NPCs=] into little puddle people (this isn't a sanctioned part of gameplay, but it's really funny). There are also dismembered cyborg versions of Goofy, Daisy, and Donald.
125* ''VideoGame/EternalDarkness'', a game rife with terrifying imagery, has the Bonethieves. Bonethieves are insectoid creatures with scythes for arms that rip into a victim's neck and enter the body, taking it over and killing the person. The body is then used to attack anyone who isn't infected.
126* ''VideoGame/TheEvilWithin'' is ''extremely'' fond of this trope. Take for example the [[NotUsingTheZWord Haunted]], the most basic enemy in the game. They are zombie-like creatures that are horribly mutilated, often impaled all over their body with sharp stakes, ''huge'' glass shards, or wrapped all over in barbed wire. It gets ''way'' worse from there.
127* Kala suffers this in ''VideoGame/{{Evolve}}''. After being spliced with monster HNA, her left arm warped into a taloned appendage, a situation she made worse with the addition of cybernetics to allow her access to its innate abilities. The influence then spread, blinding her in one eye and [[https://cdn.discourse.org/turtlerock/uploads/default/original/3X/c/b/cb50450f79b9bbf2b86631b7602137fee9e95ca0.png mutating her face.]] According to her, the infection is still growing and will eventually reduce her to just another beast. And because of her clothing, we have no way of knowing how far it's already spread.
128* The ''Franchise/{{Fallout}}'' series is all over this trope like it owes it money.
129** Ghouls are humans that got lethal doses of radiation but weren't lucky enough to die. They look essentially like walking corpses, though they are actually mostly okay people, but some degenerate so much they turn into feral ghouls who attack any non-ghoul on sight. Also, the Supermutants were all once human but were exposed to the Forced Evolutionary Virus. [[spoiler:The BigBad of the first game, The Master, fell into a vat of the stuff as a human. By the time the Vault Dweller meets him, he's a mass of mutated flesh stretched throughout the foundations of his base, merged into his computers, and has absorbed many other living things/people (minds and memories included)]].
130** Just look at Harold. In the first game, he looks like an ordinary ghoul. In the second, he has ''a tree branch growing out of his head''. In the third, ''the tree branch grew into a full-sized tree, trapping Harold inside and shuffling his organs around in its root system''.
131** Some of the post-war fauna have mutated as a result of long-term exposure to radiation. Most notable is the brahmin, a species of cow with two heads and various other disfigurements.
132** The Centaurs of ''[[VideoGame/Fallout3 3]]'' and ''[[VideoGame/FalloutNewVegas New Vegas]]'' really exemplify this trope in all it's horror. Apparently they're mish-mashes of human and animal parts created with the Forced Evolutionary Virus. Because a picture speaks louder than words, [[http://vignette3.wikia.nocookie.net/fallout/images/b/bc/Centaur.png/revision/latest?cb=20110204015102 here you go]]. The [[https://vignette.wikia.nocookie.net/fallout/images/f/fa/Animcentaur.gif/revision/latest?cb=20120918163241 centaurs]] of [[VideoGame/Fallout1 classic]] ''VideoGame/{{Fallout|2}}'' games were much worse because they had two heads, [[MixAndMatchCritters one human, one dog]], and a mass of writhing tentacles under them. [[MultipleHeadCase The two heads apparently have different minds]] since the dog head can be seen trying to bite the human head.
133** ''The Pitt'' DLC for ''Fallout 3'' introduces [[http://fallout.wikia.com/wiki/Trog Trogs]], degenerate subhumans who attack everything on sight. Around 20% of the people exposed to the radiation and toxins of Pittsburgh for too long eventually become like this. Children born in Pittsburgh however are doomed to degenerate into Trogs. They will sometimes mumble "...thank you" or "peace" when killed.
134** The ''Point Lookout'' DLC for ''Fallout 3'' gives us the lovely [[http://fallout.wikia.com/wiki/Swampfolk Swampfolk]], degenerate rednecks who got the way they are through 200 of incest, [[ThePlague exposure to the New Plague]] and plain old radiation exposure.
135** ''Mothership Zeta'' has the aptly named [[http://fallout.wikia.com/wiki/Abomination Abominations]], [[WasOnceAMan people]] who were [[AlienAbduction captured]] by the [[LittleGreenMen Zetans]] and experimented upon. Like the Trogs above, they will sometimes mumble "thank you" when killed.
136** ''VideoGame/FalloutNewVegas'' has [[spoiler:Mr. House, who has been alive since long before the war. He has been kept alive for over 200 years by using a specially-designed "hibernation chamber" that hooks his mind into the Lucky 38 casino and his army of security robots. After all this time, his physical body has withered into a mummified-looking husk.]]
137** The [[spoiler:residents of Vault 22]] were exposed to PuppeteerParasite mushroom spores as a result of a twisted [[CorruptCorporateExecutive Vault-Tec]] [[MadScientist experiment]] and were turned into savage [[PlantPerson Spore Carriers]] that walk on all fours, are covered in moss, have mushrooms growing on their back and [[EyelessFace no longer have eyes]]. They can also [[ActionBomb explode]] as a SuicideAttack.
138** The ''Dead Money'' DLC to New Vegas introduces the Ghost People, construction workers of the [[DeathWorld Sierra Madre Casino]] who were exposed to the [[DeadlyGas Cloud]] while wearing their [[HazmatSuit hazmat suits]]. This means they stayed alive long enough to mutate into something not quite human anymore. [[AndIMustScream They can't remove their suits]] [[ClingyCostume because the joints have rusted shut]]. They have a raspy VaderBreath and you absolutely need to disintegrate or dismember them to make sure they stay dead, and in the later case what you can see their flesh is a glowing green with similarly colored blood. [[ExtremeOmnivore Dog]] occasionally devours them and comments they have pockets of pressurized gas inside them that make a "Hssss" noise when he bites into them.
139** The [[http://fallout.wikia.com/wiki/Tunneler Tunnelers]] of the Divide in the ''Lonesome Road'' DLC have lived in radioactive tunnels for 200 years. ''They do not even look human anymore''.
140** From the same DLC as the Tunnelers come the [[http://fallout.wikia.com/wiki/Marked_men Marked Men]], people who were [[FlayingAlive flayed alive]] by the sandstorms of the [[DeathWorld Divide]] and turned into red muscle ghouls by the intense radiation, which means they are in [[AndIMustScream constant pain]] and [[FateWorseThanDeath are continuously kept alive]] by the radiation and ThePowerOfHate combined.
141** ''VideoGame/Fallout4'' introduced [[http://fallout.wikia.com/wiki/File:Fo4-bloated-glowing-one.png Bloated Glowing Ones]] feral ghouls. They are [[ExactlyWhatItSaysOnTheTin bloated]] with what is either tumors or radioactive pus sacks bulging under their skin.
142* Most of the ghosts in ''VideoGame/FatalFrame'' fit this trope.
143** Broken Neck from [[VideoGame/FatalFrameI the first game]] is a particularly memorable example.
144** The Blinded Ghost. ''"My eyes! Give me back my eyes!"''
145* ''Franchise/FateSeries'':
146** ''VisualNovel/FateStayNight'':
147*** [[spoiler:True Assassin]] enters the world by [[spoiler:''eating his way out of the fake Assassin''. Who is still conscious and chatting with it. There's a little too much detail about said event, plus the implication that however inhuman True Assassin looks later he is ''much'' less so when he first shows up]].
148*** [[spoiler:Shinji being attached to a faulty Grail and becoming a mutant lump of expanding flesh.]]
149*** One of Shirou's abilities is to [[spoiler:turn into swords]]. No, it is not nearly as cool as it sounds, that's why it's on this page. ...Well, okay, it's cool, but it's definitely ''not'' a good thing at all and if they had illustrated the final result it would have been rather creepy. Even worse, that reaction can be ''completely instinctive in response to extreme pressure or stress''.
150*** [[spoiler:[[TheWormThatWalks Zouken]] rebuilds his form each time his old body breaks down by infecting and fleshcrafting some new victim with his worms]].
151*** There's also Rider's Noble Phantasm, Blood Fort Andromeda, which slowly dissolves everyone inside its area of effect into blood. First their skin melts off, followed by the rest of their flesh, and the bodies are merged together while they are still alive until they are finally absorbed completely. People close enough to the origin of the effect will have all their blood instantly vaporized.
152*** And then there's [[PoweredByAForsakenChild the way Kotomine provides prana for Gilgamesh]]...
153*** Happens to Shirou in a few Bad Ends, such as [[spoiler:swords erupting from inside his chest]] and [[spoiler:having all his limbs removed and his remaining body used as a wand by Caster]].
154** In ''[[VisualNovel/FateHollowAtaraxia Fate/hollow ataraxia]]'' Caren Ortensia's body reacts to the presence of evil spirits by having spikes erupt from her skin.
155** ''VideoGame/FateExtra'': The Innocent Monster skill is essentially a condition that affects Heroic Spirits that had rumours about them overtake the facts. What does this mean for Creator/HansChristianAndersen? Well, in his case the rumour was "all the bad things that happen to his characters are things that actually happened to him". So beneath his clothes his skin is covered with scales, incurable and painful burns, endless scars, and so on and forth... Also, that condition sticks to him every time he's summoned.
156** ''Literature/FateApocrypha'': Spartacus. Dear god, Spartacus. His ability is basically an over-reactive HealingFactor, as not only he recovers from injuries, but his body and muscles overgrow to the point that he can -- and does -- end up as a giant insane FleshGolem that devours everything and sprouts extra limbs. ''VideoGame/FateGrandOrder'' retains this to a degree -- while he never gets outright grotesque his muscles and limbs do change volume and size as he fights.
157** ''VideoGame/FateGrandOrder'':
158*** Cu Chulainn Alter is the result of [[spoiler:Medb wishing to the Grail for the perfect king and partner]]. What happened was that he fused with Curruid Coinchen -- the sea monster from which Gae Bolg was made -- and now he has a spiked tail larger than his own body, and many, ''many'' more spikes growing out of him as a twisted form of BioArmor. In addition, the power of his spear has increased so much that when he throws it, ''his arm is torn off his body''. He can heal it, but it does nothing for the pain. It's also implied that he is in constant agony because of all those spikes.
159*** Have fun trying to figure out Karna. Unlike most examples of this trope, he looks [[{{Bishonen}} incredibly beautiful]], but the more you think about it the more wrong he gets. He has a giant red crystal embedded right in the middle of his chest, his skin except said chest area, neck, and head is pitch black -- to the point that many people, including official ''FGO'' artists, mistake it for SensualSpandex -- with the rest of his skin being paper white, and his golden spiked armor grows out of his own body. That includes the part that covers his crotch, and the earring. In addition, in contrast to other male characters designed by the same artist[[labelnote:Explanation]]''FGO'' employs several different artist, and many of them normally design male characters with no nipples, but not pako who designed Karna[[/labelnote]], Karna is deliberately designed with no nipples. Along with the... obvious lack in crotch area, makes you wonder about how his body functions.
160*** But wait, ''it gets crazier''. Karna's SuperForm is well... a biological impossibility. The wheel-shaped earring has replaced the palm of his left hand -- as in, ''his fingers are growing out of it''. The golden armor has been transformed/replaced by glowing pinkish vein-things that while still cover his crotch, continue on his skin and replace the crystal with a glowing eye. It's impossible to tell what the hell those are, but they are part of his body. Not to mention how he's now eminating flames from his body on top of everything.
161*** The [[spoiler:Lahmu]] in the Babylonia singularity. They look horrific enough on their own, with those... mouths of theirs and the whip-like limbs, but their battle sprites... they ''twitch''... And worst of all, [[spoiler:they are made of humans]]. Those things are high-octane nightmare fuel.
162*** The Lostbelt version of Ivan the Terrible [[spoiler:doesn't even resemble a living being anymore. He looks like a horned and faceless ice statue. And by faceless, we mean that he has a black hole where his face should be]]. Worst of all, [[spoiler:he did this to himself via CannibalismSuperpower]]. Patxi -- and every other Yaga -- get a HeroicBSOD when they see him, and Patxi even displays some PTSD symptoms from it.
163*** Muramasa decides to top Shirou's [[spoiler:grow swords out of your body]] thing by [[spoiler:using said body as the material for the sword]]. Oh, and [[spoiler:he's ''possessing'' that body at the time, fully conscious of the process and willing to do it]].
164*** [[spoiler:Koyanskaya's Beast form is MixAndMatchCritters taken to its absolute extreme, as she took every single animal that died in the Tunguska event as well as some extras and fused them all with herself]]. The end result is a mammal-like form with... ''so many legs''... in ''all'' the wrong places... For starters.
165* ''VideoGame/FeverCabin'': Some of the [[EliteZombie Elite Zombies]] you encounter have had their bodies mutated in various ways. One is the Lurkers, which have grown various legs with sharp spikes at the end, as well as more mandible-esque mouths. Another one is zombies whos bodies have become very large and egg-shaped, and have swollen and elongated their tongues to the point they're always hanging out of their mouths.
166* ''VideoGame/FearAndHungerTermina'': The effect of Moonscorch on the participants is downright horrific, with each becoming a series of terrifying beasts or mutated bodies.
167** Daan seemingly loses his mind, gains a horrifying image of a cat, and becomes Pocketcat. He then is able to sell you certain items for severed heads.
168** Abella's upper body loses any obvious female traits, becoming highly muscular. Most importantly, Abella's face is horrifically mutated, looking like the offspring of a space alien and an elephant. It is multiple timers larger than a human head could feasibly be, and has a trunk that can create a noise that pops heads.
169** Marina's body is bent backwards at an awkward angle. She has grown a new head where her crotch used to be, grown a new set of arms near the first, and has said limbs bending backwards in an impossible way. Most concerningly, where her original head used to be is a gigantic human-sized cocoon that appears to be wrapped up in strange organic material.
170** Samarie's body barely resembles the original form she had. Were it not for her breasts still visible, you'd barely be able to tell it was originally a human woman. Her skin is black and looks like numerous strands of intestine. Her lower body is bloated, her arms and legs look decrepit, and her head appears to have had the skin and one eye flayed off of the front, and stretched across a ring that is stuck to her skull.
171** Henryk mostly resembles his previous form, but with his head looking like a potato sack with two large pig-like ears. His body is much more massive and hunchbacked, but otherwise the same.
172** Marcoh's legs and head appear to be stitched pale, and his head looks like a large worm, but his body is a scaly monstrosity with a half-dozen mouths adorning it. He is always seen dragging a body, which he uses as a weapon.
173** Tanaka has removed the upper part of his business suit. He still looks human, but the entire right side of his body, all the way up to his head, seems to have some sort of blue crystal glass growing from it. The strangest thing is some odd device attached to Tanaka at the neck which obscures most of his face from view.
174** O'saa looks almost identical in clothes and limbs. The obvious difference is his bizarre head, which looks like an amoeba made of human flesh.
175** Olivia looks like a floating Iron Maiden with bladed arms. Her entire body has become iron, and the implication is that the form is terribly painful. Unlike the others, she doesn't appear to have any organic body left.
176** Caligura's body barely resembles humanity anymore, having more akin with a horrifying toad. The head is split open and runs down the entire body, with the stomach of the creature resembling a gigantic scrotum. It also has thirty new limbs all over the base of its body, and the body of the creature looks as if it is rotting away.
177** Karin's body becomes a giant segmented bird, with her arms begin feathered wings. He entire back is covered in enemies, and her face no longer looks human.
178** Levi runs about naked, his head encased in some bizarre leather that stretches out from his face in a long line, superficially resembling a sniper rifle made of organic tissue.
179* ''Franchise/FinalFantasy'':
180** ''VideoGame/FinalFantasyVII'':
181*** The boss fight against Hojo: you first fight him as a human, but after you beat him, he turns into Helletic Hojo, a freaking hideous, writhing mass of flesh that wouldn't look out of place in ''Franchise/ResidentEvil''.
182*** The backstory involving Jenova has quite a bit as well. As it's the weapon of choice was a virus that drives humans insane before turning them into monsters.
183** In ''VideoGame/FinalFantasyXIV: Shadowbringers'', the process of turning into a [[EldritchAbomination sin eater]] entails another sin eater implanting a portion of primordial Light into the bodies of their victims. The resultant aetherical imbalance causes the victim's skin to turn plaster white, their hair to fall out, and their body to become wrapped in a cocoon until hatching into a porcelain-white monster with a body that can be described conservatively as "twisted".
184* ''Franchise/FiveNightsAtFreddys'':
185** Phone Guy mentions in [[Videogame/FiveNightsAtFreddys1 the first game]] that if the animatronics catch the player, they will be stuffed into a Freddy Fazbear suit, whose crossbeams, devices and wires would gore and crush them to death, leaving only their eyeballs and teeth to pop out the front of the mask (where the danger's at its worst). The Game Over screen shows this occur, by the way.
186** In ''VideoGame/FiveNightsAtFreddys3'', there's mention of hybrid suits, that ''could'' be used if you cranked the spring-loaded machinery out of the way. If you ''don't'' crank them up correctly, however, they'll just spring back into place a few moments after you've put it on, resulting in a similar, if maybe even ''slower'', but certain death as the animatronic parts slowly crush your body into paste. [[spoiler:As happened to the murderer, who tried to hide from the children's ghosts in the only such suit left]].
187** The previously mentioned process helped to create Springtrap, the BigBad of the third game. You can visibly see human organs when looking at him, further validating the fact that an actual human being has been [[spoiler:''stuck within that suit for at least 30 years'']]. Even worse, [[http://i.imgur.com/YNMEDKB.jpg there's an image clearly showing just what's underneath]] -- namely, the chest is ''gone'' and has more or less been crushed into the animatronic torso, the eye sockets and mouth are pulled open, and the eyes appear to have been popped out by those of the animatronic.
188** The ultimate fate of "Eggs Benedict" in ''VideoGame/FiveNightsAtFreddysSisterLocation''. [[spoiler:Tricked into walking into the scooping room by Ennard, who is a whole 'nother level of this trope, he has [[FlayingAlive his bones and organs removed]], letting Ennard wear his skin like a suit to escape the facility.]]
189* Quite a bit in ''VideoGame/GearsOfWar'', and loads and loads of it in the ExpandedUniverse. Lambent humans/Locusts, Sires, the fact that Locusts came from Sires who came from humans thanks to the Imulsion, the genetic experimenting and horrible mutations, and not to mention the gratuitous {{Gorn}}, and so forth, and all of this just scratches the surface of the video games ''alone.''
190* The Malichor in ''VideoGame/{{GreedFall}}''. It's a plague that initially starts out as what feels like a cold, but progresses to blindness, black blood, and rotting the flesh of the victim while they're ''still alive''.
191* The Affliction in ''VideoGame/GuildWars: Factions'', a plague which initially makes those afflicted go mad and attack anybody who themselves is not afflicted, and shortly after rather violently turn into a body horror. The affliction is later revealed to be [[spoiler:the work of Shiro Tagachi (a spirit of incredible strength who 200 years prior had killed the Emperor of Cantha, of whom he was the bodyguard) who was abusing the powers granted him in the afterlife, creating the afflicted instead of guiding newly dead souls to the underworld as part of his plan to return to life]]. This happens slowly to [[spoiler:Varesh Ossa, whose close tie to Abaddon and his minions caused her first to go bald while developing ridges on her forehead. On death, those ridges transformed into extra eyes as she was resurrected as a Margonite]].
192* The bizarre monsters of ''VideoGame/{{Gyossait}}'' are supposed to be mutated humans -- you even get to see a human mutating into a strange giraffe-like creature. And then there's Uzaza, who ''somehow'' went from a normal human being to a giant, tentacled NightmareFace after grafting a goddess's heart into himself.
193* In the ''VideoGame/HalfLife'' series, parasitic creatures called headcrabs latch onto the skulls of humans, taking over their body and causing gross mutations. These include growing elongated claws, a gaping maw in the chest, and rotting.
194** In ''VideoGame/HalfLife2'', this was changed so that headcrab zombies "merely" have slightly pointed fingers and a large hole in their abdominal cavity. This is compensated by the inclusion of both fast zombies, which are ''missing all of their skin'' and sound like a dog being run over by a steam roller, and poison zombies, which are bloated to twice their width and throw black hissing headcrabs at you. If played backwards, the moans of the regular zombies can clearly be heard to say "Help God Help! Help me!" That player could also remove the headcrab from the host, revealing that the host's face is ''[[AndIMustScream locked into a perpetual scream]]''. Thanks, Valve.
195** The Overwatch soldiers fought throughout and the Stalkers seen in the Citadel are what the Combine has planned for humanity, draining them of "unnecessary" organs and fluids and cramming them with electronics. For bonus points, the other Synth units appear to be this same process applied to various alien species, implying the Combine have done this to who knows how many planets.
196** And to mix things up, there's the Zombine: A Combine soldier taken over by a headcrab. Unlike regular zombies, they are still connected to the [[EnemyChatter Combine network]]. Plus, take off the headcrab, and you'll get a worse sight than that frozen scream: [[OffWithHisHead everything above its jaw is gone.]] It goes to show you how far Combine have modified its Overwatch Soldiers seeing how they can still talk and transmit information, implying that these are pre-recorded lines that play when necessary, freeing up parts of the brain.
197* ''Franchise/{{Halo}}'': The Flood. An extragalactic [[TheVirus virus]] with a HiveMind. Infection forms the size of facehuggers can attach themselves to any body, ''living or dead'', and completely take over their nervous system while simultaneously mutating them into tentacled combat forms or bloated carrier forms. And they ''always'' swarm you. To make matters worse, the Flood can regrow their entire population if ''one'' infection form is left, and they gain all the victim's memories.
198** In ''VideoGame/Halo3'', the Flood Infection Forms can jump onto a human, Elite, or Brute, ''burrow into their chest'' (or mouth, in the case of the Brutes), and mutate them into a combat form within a few seconds, complete with horrified screaming from the victim (the cries of the Marines are particularly jarring), sensory tentacles popping out from the point of penetration, horrific gray flesh sprouting across the victim's body, seeing the ''actual head'' of the victim. Perhaps the most disturbing part is that when an Infection Form jumps on a character, the NPC will grapple with it for a few seconds to give the player the chance to shoot it off. This means that if any allies are infected, ''it's all your fault''.
199** A Marine in the level "[[NamesToRunAwayFromReallyFast Floodgate]]" nicely spells it out for you:
200--->'''Marine:''' I... I didn't have a choice...! The L.T... the Sergeant... ''they were all infected!'' I could see it crawling... ''sliding around beneath their skin!'' ''[sobs]'' A-And then they got up... they s-started to talk! Oh, God! Their voices! ''Oh, God! No, make them stop!'' I [[MercyKill did them a favor]]... Y-Yeah, that's it; I ''helped'' them! ''[sobs]'' Maybe... Maybe [[DrivenToSuicide I need to help myself]]... ''[breaks out into sobs]''
201** ''Literature/TheForerunnerSaga'' shows that there were monstrous Flood forms which were visually comprised of ''multiple'' bodies.
202* ''VideoGame/HauntingStarringPolterguy'': Poltergeist Polterguy can summon many "fright 'ems" like a mutilated corpse in the shower or some deformed creatures.
203* In ''VideoGame/HorizonForbiddenWest'', [[spoiler:Ted Faro]] wanted {{Immortality}}. [[spoiler:He got his wish, but in the process, he became an unrecognizable blob of flesh wrapped around a geothermal reactor, incapable of movement and implied to be in constant horrific pain]].
204* ''VideoGame/TheHouseOfTheDeadOverkill'': Many of the enemies, especially Nigel and Sebastian (two twins horribly fused together) and the Lobber from Overkill. And from the same game, Varla Guns, after Warden Darling put his mother's brain in her head... and apparently forgot to reattach the back of her cranium. Extended Cut adds the Dual Boss Sindy & Coco, respectively a Distaff Counterpart to the above Lobber in the looks department and a mutant monkey stripper.
205* In the ''VideoGame/{{Icescape}}'' series, several dead people turn up mutated in horrific ways, warped as if its flesh was turned inside out. [[spoiler:This is actually the result of a weapon used by [[TheGreys aliens]] nearby, which rewrites the target's DNA with random code.]]
206* In ''VideoGame/{{Iji}}'', we have Beasts. One would assume they are robots or trained animals. The reality, as the enemy encyclopaedia reveals, is much worse. [[spoiler:Those things used to be ordinary Komato.]]
207* In ''VideoGame/IndianaJonesAndTheFateOfAtlantis,'' the Colossus of Atlantis is introduced as a machine that was used to transform humans into gods; unfortunately, judging by the hideously deformed bones scattered throughout Atlantis, there were several failed attempts before [[KingOfAllCosmos Nur-Ab-Sal]] got it right. But even in light of this, [[ThoseWackyNazis Klaus Kerner]] attempted to use the Colossus on himself during the climax, believing that his Aryan genes would make him immune to that sort of thing. Needless to say, he's proven very wrong: after a brief moment of glory, his left eye swells until it's forced shut, then he begins shrinking rapidly until he's transformed into a twisted little minotaur.
208* ''VideoGame/InFamous2'' and the Corrupted. Only during one heroic mission do you witness [[spoiler:Bertrand causing]] the mutation of a perfectly normal man into a Corrupted. It is not quick, and you can hear the man's continuous screams of agony.
209* ''VideoGame/Inside2016'' has a few cases. You encounter enslaved people that can be moved around by you with mind control and later find a few of them suspended for body-part-harvesting, some now being little more than quadriplegic blobs that can do little more than flop around in their attempts to follow your commands. Others have broken necks and heads dangling onto their back. What tops it though is [[spoiler:where all the amputated limbs apparently went. In the end you find an amorphous blob, several times an adult's size, comprised of various arms and legs suspended in some kind of tank. Not only that, in your attempts to free the blob (called "Huddle" by the developers), you get violently assimilated by it. For the rest of the game, you control an unstoppable mass of moaning legs and arms trashing through a research station]].
210* Poor, poor D-Caf in ''VideoGame/JurassicParkTheGame''. He's bitten by Troodon, which is bad enough, since the venom puts him in a catatonic state. Be sure you can handle the {{Squick}} before checking the following spoiler-tag, even if it's obscured in-game... [[spoiler:they then ''lay their eggs'' in his abdomen, effectively using him as a living nest and food source for the young (a practice done by parasitic wasps in real life). And the worst part? He's still technically '''ALIVE''']].
211* ''VideoGame/KerbalSpaceProgram'': This is what befalls the poor unfortunate kerbals who fall victim to [[GoodBadBugs the kraken]]: their limbs flail, distort and stretch way beyond what they should, looking more like what'd happen if you tied a bunch of ropes to a faulty propeller than a humanoid.
212* ''VideoGame/KeroBlaster'': Throughout the course of Normal Mode, Nanao slowly becomes horribly swelled up, deformed, and discolored [[spoiler:as a result of being possessed by one of the "things"]].
213* ''Franchise/TheKingOfFighters'':
214** Ron, former leader of the Hizoku clan and a subordinate of NESTS, is able to teleport in and out of the fight. The process involves him [[DemBones rotting away into a skeleton]] when he leaves, and his body reforming from said skeletal state when he enters.
215** K9999, as one of [[CaptainErsatz his many traits borrowed from]] ''Manga/{{AKIRA}}'''s Tetsuo Shima, has a super move called "Help! My power... It's running wild!" in which his arm mutates into a multi-hitting wad of flesh. [[spoiler:As Krohnen, "Calamity Overdrive" looks far less disturbing, as he now morphs his arm into a cybernetic claw instead]].
216* If you mess up any of the spells in ''VideoGame/KingsQuestIII'', you end up with some pretty awful deformities that result in death.
217* ''Franchise/{{Kirby}}'':
218** King Dedede gets subjected to this courtesy of Dark Matter in ''VideoGame/KirbysDreamLand3'' and ''VideoGame/Kirby64TheCrystalShards'', where in the second phase of the battles against him, his belly will open up to reveal a projectile-shooting eye or become a toothy mouth that he'll try to chomp on Kirby with.
219** ''VideoGame/KirbyAndTheForgottenLand'' manages to one-up this ''big time'' with [[spoiler:Fecto Forgo, an alien that assimilates the Beast Pack into itself to become a giant blob with deformed, partially digested faces all over it. Even before that happens, the Beast Pack’s leader, Leongar is shown to be possessed by Fecto Forgo, and the whole ordeal is clearly extremely painful for him, as his body language when he fires his [[BreathWeapon laser beam]] resembles a person vomiting]].
220* Rakghouls in ''VideoGame/KnightsOfTheOldRepublic''; here's the [[http://starwars.wikia.com/wiki/Rakghoul Wookieepedia article]]. In their first appearance, they're somewhere between zombies and werewolves; bitten humans have a chance of being infected and transforming if not cured. They shamble on all fours and balance on their hind legs like nonhuman apes, their eyes have been moved to the sides and squeezed shut, their skins are either a shiny off white or a rough red; altogether they're just monstrous. Rakghouls are essentially ravenous animals.
221** Darth Malak is shown during a cutscene near the ending without his metallic jaw prosthesis, and what is shown beneath it is '''[[http://images.wikia.com/starwars/images/7/77/Malak_Jawless.jpg more than enough]]''' to qualify of fitting this trope exquisitely.
222** ''VideoGame/StarWarsTheOldRepublic'' has a return to Taris and several sidequests where evidence points to the rakghouls retaining at least some measure of their previous sentience.
223* ''VideoGame/TheLastOfUs'' gives us two simple words: Cordyceps infection. In four stages:
224** 1. [[http://m.ign.com/wikis/the-last-of-us/Runners Runners]]: Humans freshly infected with the fungus. Not too much horror, but enough to be unnerving.
225** 2. [[http://m.ign.com/wikis/the-last-of-us/Stalkers Stalkers]]: The fungal growth starts to overtake their skull, and they hide in shadows, waiting for a survivor to run afoul of them.
226** 3. [[http://m.ign.com/wikis/the-last-of-us/Clickers Clickers]]: Their skulls have split open, and the fungal growth has destroyed their sense of sight. But they can still use [[http://en.m.wikipedia.org/wiki/Human_echolocation echolocation]] to find you.
227** 4. [[http://m.ign.com/wikis/the-last-of-us/Bloaters Bloaters]]: The most advanced stage, these guys are less human and more walking piles of fungal growth. Strong enough to TearOffYourFace, and able to launch spore bombs, Bloaters are an enemy you'll hope you'll never have to see again.
228* ''VideoGame/Left4Dead'':
229** Though the ordinary Infecteds, Hunters, and (for the most part) Witches in ''VideoGame/Left4Dead'' probably don't experience much body horror, it's pretty {{Squick}}y to imagine what it must be like to watch the formation of a Smoker, Boomer, or Tank.
230** ''VideoGame/Left4Dead2'' gives us the spitter, jockey, and charger. According to the commentary in ''Left 4 Dead 2'' one of the developers had a "nightmare" folder on his computer with reference photos of people with horrible diseases for reference for making infected. These were so bad that not a single one of them was used as reference for the game.
231* ''VideoGame/LegacyOfKain'':
232** The Vampire evolutions, for the most part, were a pretty good deal (if you didn't mind having leathery skin), with Kain and Vorador being the example of what a true evolution would look like. But when Kain's Corruption sets in amongst his (Not-Balance Guardian) Lieutenants and their Broods, and they began devolving, you can't help but imagine that some of them started to think, "no immortality is worth this."
233** The art in ''Nosgoth'' shows in detail what began to happen as the various clans Dark Gift's side effects began to kick in. [[https://www.nosgoth.com/blog/vampire-clan-evolved-skins-the-deceiver-of-clan-zephonim The Zephonim]] and [[https://www.nosgoth.com/blog/vampire-clan-evolved-skins-the-summoner-of-clan-melchahim the Melchiahim]] got the worst of it at first, with the rest getting their own lesser yet still grotesque {{metamorphosis}}.
234** By the events of ''Soul Reaver'', the other clans have been wrecked as well, and are pretty much animals at this point.
235** Believe it or not that's not nearly as bad as what happened to Kain's Lieutenants. Even Raziel, the one that was spared this fate, doesn't get off scot free -- becoming a blue wraith of bones and muscle that's missing a jaw.
236** Strangely though, the survivors of Raziel's clan have the reverse happen. They go from blood-starved and malnourished, to [[https://www.nosgoth.com/blog/vampire-clan-evolved-skins-the-sentinel-of-clan-razielim this]] when they finally manage to satiate their hunger in battle.
237* ''VideoGame/LegendOfLegaia'' is full of some ''seriously'' {{Squick}}y villains. And then there's the regular people, who wear symbiotic creatures named Seru that give them great abilities (enhanced strength, speed, flight, ect.) But when under the influence of the Mist, they become parasitic monsters that force their way into people's skin and corrupt their minds, effectively turning them into [[FateWorseThanDeath moaning, limping zombies]]. The process renders them ageless and some [=NCPs=] claim that they were just conscious enough to realize what was happening to them.
238** By the end, villains Songi and Cort are so deformed that they're not even recognizable as being human. They're so grotesque and misshapen that it's best to see the main page for a long explanation of what the Seru have ultimately done to their bodies. And this doesn't even cover other villains like Dohati, Zeto, Van Saryu, and Zora, all of whom have become infused with their Seru and are no longer human in appearance or mannerisms.
239** The three Womb Levels also count. Both Conkram and Rim Elm are engulfed by a massive Sim-Seru that has fused with the town and all its inhabitants. As you venture through the former, you see people trapped in walls, fleshy floors and veins that pulse with the Seru's blood, guards that open a pathway by splitting up the flesh that joins them together, and an overall oppressive atmosphere. It's quite simply a HellOnEarth. There are heavy implications that the [[AndIMustScream great pain has driven most of Conkram's inhabitants insane]].
240** The laboratory where young "brides" are fed to EldritchAbomination Juggernaut. They're trapped in restrictive gowns and capsules that slowly drain them of their life-source until they are finally and directly consumed by Juggernaut. After defeating Van Saryu and shutting down the feeding machine, it's revealed that only a handful of brides returned to the city, implying that the majority of the girls were fed to Juggernaut before you could save them.
241* ''Franchise/TheLegendOfZelda'':
242** ''VideoGame/TheLegendOfZeldaOcarinaOfTime'':
243*** The House of Skulltula... that father and his five sons used to be ''human''.
244*** The MiniBoss [[HumanoidAbomination Dead Hand]] looks less like a ''Zelda'' enemy and more like a ''Silent Hill'' reject: to resume, it is a fat humanoid thing with [[{{Fingore}} giant stumps]], [[GhostlyGape a giant mouth and tiny black holes]] [[EyeScream where its eyes should be]], a LongNeck, no legs, and CreepilyLongArms beneath its body with long-nailed hands at their extremity.
245** ''VideoGame/TheLegendOfZeldaMajorasMask'':
246*** The vital [[TransformationTrinket mask transformations]] have some of the most [[PainfulTransformation painful]] {{Transformation Sequence}}s ever put to cartridge.
247*** The spider/human hybrid model is reused for some poor guy who wandered into the Swamp Spider House intending to use the Mask of Truth to find some promised treasure.
248*** There's also the guy who's turning into a Gibdo. What's worse is he has a daughter, and he was going to turn her into a Gibdo.
249** In ''VideoGame/TheLegendOfZeldaTheWindWaker'', you face a fake Ganon the end of the long staircase. The fake Ganon twists and groans as he turns into his true form: a puppet controlled by the real Ganon that's as creepy as himself.
250** Link's first transformation into a wolf in ''VideoGame/TheLegendOfZeldaTwilightPrincess'', when thrown into the Twilight Realm for his first time, has a theme of the wolf ''bursting'' out from inside him.
251* ''VideoGame/LobotomyCorporation'' features numerous abnormalities. Some are implied to have been previously human, while others are just bizarre entities. A few examples include: a pile of grotesque spherical entities with giant mouths made of mashed corpses known as "Mountain of Bodies", a cute magical girl who transforms into a bizarre serpentine beast after being speared by magical lances known as "Queen of Hatred", and a bizarre creature whose whole body is entirely censored that can turn killed targets into horrific piles of censored flesh (and it drives any level 4 or lower employees mad immediately) known appropriately as "CENSORED". The list could go on.
252* ''Franchise/MassEffect'':
253** ''VideoGame/MassEffect1'' has Husks -- organics captured by the Geth are put onto devices that impale them, replaces their organs with cybernetics and they are effectively turned into cyber-zombies. Also, during the final boss fight, Saren's [[spoiler:corpse is re-animated into an avatar of Sovereign]] in gruesome detail.
254** The [[NightmareFuel vision]] Shepard gets on Eden Prime [[spoiler:shows Proteans being tortured and [[UnwillingRoboticisation merged with machinery]]. [[NothingIsScarier We don't see all that much]], but we hear screaming, [[FateWorseThanDeath lots and lots of screaming]]]].
255** The background of Dr. Saleon, as told by Garrus. People were used as living incubators for clone organs, and if the organs were bad, why, the good doctor would just leave them in there. When you find "Test Subjects" on Saleon's ship, they look and behave exactly like [[https://vignette.wikia.nocookie.net/masseffect/images/e/e5/Thorian_Creeper.png/revision/latest?cb=20140614190322 Thorian Creepers]]. ''What the hell did Saleon do to his victims to turn them into this?''.
256** It gets worse in ''VideoGame/MassEffect2''. After all, you get Abominations, which are Husks that glow red and explode; Scions, which are three humans fused horribly togther; and Praetorians, tanks made from 30 people fused together and powered by dozens of severed human heads. Plus, the Collectors themselves...
257*** When you find a dead Collector [[spoiler:on the Collector Ship,]] EDI [[spoiler:determines that the Collectors are Protheans. However, these Protheans show signs of "extensive genetic rewrite," including three missing chromosomes, plus extensive cybernetic modification. If you ask Mordin after the mission if he thinks the Collectors can be saved, he says "No glands, replaced by tech. No digestive tract, replaced by tech. ''No souls, replaced by tech''!"]] Then you find out that [[spoiler:this is how new Reapers are made]].
258*** You get to watch in horrifying detail just what has been happening to every one of those abducted colonists -- you find a pod in the Collector base and get to watch either a Horizon colonist named Lilith or your very own yeoman, friend, and (possibly) romantic interest Kelly Chambers ''[[NightmareFuel melt into a bloody mass while screaming in agony]]'', and there's nothing you can do to save her.
259** In the ''Overlord'' DLC, the creature known as the [[spoiler:Rogue VI]] turns out to be [[spoiler:an autistic mathematical savant who was forcibly integrated into the geth neural network by his MadScientist brother to see if the geth could be controlled]]. [[https://i.imgur.com/2DpofPN.png?1 No wonder it was screaming]] [[spoiler:"MAKE IT STOP!" -- because the overall torture wasn't enough, the poor guy has his eyelids [[EyeScream kept open by force]]]].
260** Then ''VideoGame/MassEffect3'' came out and took the horror of the husks up to eleven. We have Cannibals, batarian husks with human corpses fused on to serve as an ArmCannon. Marauders, turians transformed into husk squad leaders. Brutes, enormous krogan husks with a turian head stapled on to provide intelligence. Ravagers, rachni with two huge artillery cannons bolted on, and covered in sacs filled with baby rachni husks. Harvesters, giant insects transformed into flying Reaper monsters. And the dreaded Banshees, asari with latent Ardat-Yakshi genes, twisted and stretched out into wispy monstrosities. [[http://i.imgur.com/kxb6E.jpg Some of the concept art for Ravagers was even worse]].
261** On Mars, Shepard takes off a Cerberus assault trooper's helmet, only to find out he's been implanted with Reaper tech and looks more husk than human.
262** There's also what's happened to the Illusive Man in your final confrontation with him. He's been so implanted up with Reaper tech that ugly black veins have started growing on his face and neck.
263* The Harvesters/Ithkul from ''VideoGame/MasterOfOrion 3'' behave similarly to the Zerg, infecting other races and... reconfiguring... their bodies into freakish shapes. [[http://www.moo3.at/strategies/race_picks/lw_strat_guide.php Here]] (most of the way down the page) you can see some Ithkul -- two infected humans, and what appears to be an infected Meklar (yes, they ''can infect robots too'')!
264* ''VideoGame/MasterOfTheMonsterLair'':
265** Gloop's LegoGenetics can qualify as this if you have a good imagination. Try picturing a creature with the torso of a gigantic bull, the arms of an octopus, teeny-tiny little [[MixAndMatchCritters crowbat]] feet, and a fleshless skull for a head.
266** The ogre cyclops seems normal enough, until it decides to fire its EyeBeams... and its ''head splits open across the middle to expose its brain''.
267* In ''VideoGame/MegaManZero 4'', the genocidal BigBad Dr. Weil is revealed to have his mind trapped in a self-regenerating mechanical suit of armor, which, in theory, makes him "immortal". When [[spoiler:TheDragon, Craft, rebels, destroying Weil's base of operations with the [[KillSat Ragnarok satellite]]]], apparently taking care of Weil. That is, until the end of the game, [[spoiler:where we see Weil actually survived, and his regenerative armor decaying but still functioning, showing robotic parts meshed with his flesh]]. Not something to be shown to kids. And then there's [[spoiler:his OneWingedAngel, where his armor, but not himself, grows to enormous size. It's obviously a PainfulTransformation, as Weil screams during the whole phase, and all the ''blood'']].
268* ''Franchise/{{Metroid}}'':
269** The X Parasites in ''VideoGame/MetroidFusion'' take over sapient beings, consume their bodies and then mimic their DNA, becoming perfect physical copies and gaining their intelligence...but without any of their higher emotions, living only to feed and reproduce. The Metroids were created to hunt and destroy them, confining them to SR-388, but Samus was hired to exterminate the Metroids. [[NiceJobBreakingItHero Oops]]!
270** In ''VideoGame/MetroidPrime3Corruption'', Samus is infected by TheCorruption and is slowly transforming into her EvilTwin, Dark Samus. As each Leviathan core is defeated, her body vomits Phazon and does other horrors as her body becomes more corrupted.
271** In the other two ''VideoGame/MetroidPrimeTrilogy'' games, there is also Body Horror in the mutations caused by said ''Corruption'', and {{Enemy Scan}}s of some dead creatures (mutants in the [[VideoGame/MetroidPrime first]], victims of the Ing in ''VideoGame/MetroidPrime2Echoes''). ''Prime Trilogy'' also gives us the BlackComedy example in the story about Space Pirate Science Team attempting to reverse-engineer Samus's Morph Ball.
272--->"All attempts at duplicating it have ended in disaster: four test subjects were horribly broken and twisted when they engaged our Morph Ball prototypes. [[ComedicSociopathy Science Team wisely decided to move on afterward]]."
273** ''VideoGame/MetroidDread'': [[spoiler:Raven Beak X]] generally looks like Kraid having the head and limbs of [[spoiler:Raven Beak]] fused with his brain and jaw, and that's not even getting into the other bosses mixed in with this... thing.
274* This is a key mechanic in ''VideoGame/{{Misshapen}}'', where you can't harm the strange monsters after you but can create lumps on their bodies with varying effects. It's possible to make ''entire structures'' with this.
275* ''VideoGame/{{Mother}}'':
276** ''VideoGame/Mother3'' has the various Chimeras. They range from standard, somewhat silly MixAndMatchCritters to some... very disturbing combinations. The colorful, cartoony graphics don't help.
277** Master P[[spoiler:orky]] is at ''least'' one thousand years old, and has not aged well. He literally looks like a bloated, pale corpse.
278** The fangame ''[[VideoGame/CognitiveDissonance Mother: Cognitive Dissonance]]'' gives us the lovely visual of Giegue's body stretching and distorting as his PSI tears him apart, starting to become the EldritchAbomination known as Giygas.
279* Dr. Strangeglove, the antagonist of ''VideoGame/MoshiMonsters'' has a design that only shows his eyes and mustache only, not the rest of his face. But the movie does indeed give him a mouth... [[https://static.wikia.nocookie.net/moshimonsters/images/0/04/Gillibean_Strangeglove.jpg/revision/latest?cb=20151025191347 that’s located on his coat.]]
280* [[spoiler:Inugami]], one of the {{Final Boss}}es of ''VideoGame/MuramasaTheDemonBlade'', provides enough BodyHorror to last the entire game, opening up gaping wounds in reality full of sickle-wielding skeleton arms, contorting his body in disturbing ways as he teleports around, and transforming into an infinitely long maw of teeth as one of his attacks.
281* ''VideoGame/TheNeverhood'': In the credits, there's an illustration of Klaymen proudly opening his malleable chest to display his internal organs.
282* ''VideoGame/NexusClash'':
283** The game takes place in a world that contains both plague zombies and necromantic zombies. Thanks to GoodBadBugs, it's possible for a person's corpse to get ripped in half, with each half reanimated as a different kind of zombie. Which are then forced to fight each other. Thankfully, you don't have to [[WebGames actually watch]] this happen, but the game describes it to you vividly enough.
284** There are also the ways your character evolves as you level up. Angels mostly become inhumanly perfect, while Seraphim become clockwork full-body cyborgs. Revenants and Liches become withered walking corpses. Demons become a number of horrible things, like a person covered in fanged mouths with no eyes (Void Walker), an amorphous screaming blob (Doom Howler), or TheWormThatWalks (Wyrm Master).
285* In ''VisualNovel/NineHoursNinePersonsNineDoors'', all the participants of the Nonary Game have had bombs planted in their digestive tracts which will go off if they either tamper with the bracelets mounted on their wrists or fail to find the deactivator within 81 seconds after passing through a numbered door. For those that fail, the game provides detailed, absolutely visceral descriptions of their blasted bodies.
286* ''VideoGame/NintendoWars'': Creeping Derangea from ''Advance Wars: Days of Ruin'' causes flowers to grow under the skin and then break out. Painful, but it [[spoiler:initially]] only infects people under 20.
287* ''VideoGame/NobodySavesTheWorld'':
288** [[EldritchAbomination The Calamity]] infects everything, including people, with a horrible [[MeatMoss fleshy fungus]]. At later stages of the infection, those people are completely covered in fungal growths, losing the ability to move or talk, but they are [[AndIMustScream still alive]].
289** The citizens of Mutown have all been [[NuclearMutant mutated]] after a meltdown on a nearby nuclear plant. The people with the more extreme mutations look like grotesque piles of mismatched limbs, though they don't seem to mind.
290** Peptro, one of the contestants in the Colosseum, can shapeshift into a pterodactyl, but he botches his transformation out of nervousness and turns into a [[ShapeShifterMashup nasty mix of both forms]].
291* ''VideoGame/NuclearThrone'': Taking place in a post-nuclear wasteland, the game is rife with this stuff:
292** Among the playable mutants, Eyes with the {{extra eyes}} covering his head (and {{no mouth}}) and Melting with his melting flesh and [[TwoFaced half-exposed skull]] stand out as particularly horrific.
293** Some of the mutations you can gain while leveling up elicit mild Body Horror. "Bolt Marrow" and "Shotgun Shoulders" depict their respective ammunition types jutting out of a mutant's body. "Boiling Veins" depicts Melting's skin ''on fire''. "Long Arms" lengthens Eyes' arms to be [[CreepyLongArms uncomfortably long]].
294* ''VideoGame/{{Observo}}'': The monsters in the game look like two or more people fused together. The best way to describe their appearance would probably be to compare them to the frozen corpse from the beginning of ''Film/TheThing1982''.
295* ''VideoGame/{{OFF}}'': Elsens, who usually look like men in business suits, undergo some nasty transformations when they get pissed off/go crazy and thus become Burnt. Their heads exploding into a fountain of what seems to be blood/smoke is the least of their problems.
296* In ''VideoGame/TheOuterWorlds'', cystypigs combine this with ForeignQueasine. They are a breed of pigs genetically predisposed to gain huge cysts and tumours all over their bodies, and ''this is by design''. The tumours are bacon-flavoured and slough off the pig's body easily without harming it. This "sustainable meat product" is a staple food of the people of the Halcyon colony and in a terminal log, Phineas Welles even regards this as civilised compared to how pigs were butchered for meat in the past.
297* ''VideoGame/PandorasTower'': Go ahead. Try putting off giving [[TheWoobie Elena]] the cure for her curse 'till the last minute. You will never sleep again.
298%%* This trope is the whole premise of ''VideoGame/ParasiteEve''.
299* ''VisualNovel/PartTimeJob'' has [[spoiler:Lyra becoming a severed head in a jar, Twilight and Screw Loose being sewn together and given Lyra's body to boot, and Pinkie Pie getting her hind legs replaced with giant alligator legs]]. This isn't really anything ''outstanding'' compared to other examples on this page, but what makes it even more horrifying is that [[spoiler:Fluttershy did this to make them "more interesting" so she could ''sell them to a circus'']].
300* ''Franchise/{{Persona}}''
301** ''[[VideoGame/Persona1 Megami Ibunroku Persona]]'' started the trend with Kenta Youkichi's Persona and how it's summoned. Said Persona is [[GagPenis Mara]], and it ''errupts from his stomach''. Then there is the FinalBoss of the SEBEC route, who is [[spoiler:some kind of bloated yet malnourished insectoid woman with multiple limbs in a birth-giving (or sexual} position with no face save for an oversized mouth with jagged teeth, with a gigantic penis almost the size of her body fully errect, and the tip has ''Maki's face'' on it]]. This somehow went completely uncensored. Then again, it is... almost ''too'' horrifying to understand what exactly you're seeing...
302** ''VideoGame/Persona2'':
303*** [[https://www.youtube.com/watch?v=tPIo5k2Zqu8 An animated short]] in ''Eternal Punishment'' shows in detail what exactly the Emblem Curse in the previous game ''Innocent Sin'' looked like. We are treated to a close up shot of a girl's face ''[[FacialHorror melting off]]'', complete with her ''eyeball sliding down'', completely out of nowhere. And this happened to ''half the student body''. No wonder they all wore bandages around their heads, if they had to keep their skin in place...
304*** Quite a few enemies -- especially the bosses -- are Body Horror galore. Bonus Boss Pandora whose body is vertically split in half and led together by blood-like goo? Was Sugawara whose head has been bloated into a twitching incent-like monster [[AndIMustScream while he's still concious and begging you to kill him from the pain despite being immortal?]] The "stalker" that hunts down Eriko who apparently has no sense of pain and shows up with more injuries and bandages each and every time, not even bothered by his arm breaking? The JOKERS that were ''physically transformed'' to demons? How about the FinalBoss of ''Innocent Sin'' who is a tentacled amalgamation of the fathers of each party member tied up in bondage gear?
305** In ''VideoGame/Persona3'', the [[https://www.youtube.com/watch?v=Pg06RvVzzdM main character's first Persona summoning]]. When he pulls the trigger on the Evoker to summon his Persona, he has a ''really'' creepy smile on his face, [[GlowingEyesofDoom complete with glowing eyes]]. To top it off, shortly after summoning his Persona, it gets ripped apart ''from the inside'' by another, far more brutal and powerful Persona, all while the main character is screaming and clutching his head. Turns out later in the game that [[spoiler:the Persona that clawed its way out of Orpheus is Thanatos, aka Death, who was sealed inside the main character ten years prior by Aigis. Considering that the main character's first Persona summoning is against one of the 12 major Shadows used to form the Appriser when destroyed, which also includes Death, this makes a lot of sense]].
306** In ''VideoGame/Persona5'', human shaped Shadows bloodily erupt into demons when you start a battle with them. In a number of Palaces, human shaped Shadows will also transform into {{Humanoid Abomination}}s. Additionally, when characters first awaken to their Personas, they have to rip off masks that are ''part of their faces'', causing blood to erupt as they for all intents and purposes ''rip their own skin off''.
307* In ''VideoGame/PhantasmagoriaAPuzzleOfFlesh'', the main character has hallucinations of a purple clawed hand emerging from his stomach. [[spoiler:In [[MultipleEndings one of the possible endings]], his hand is also shown mutating, having earlier discovered a TomatoInTheMirror.]]
308* ''VideoGame/{{Pikmin}}'' games:
309** ''VideoGame/Pikmin2'':
310*** For being such a light-hearted game otherwise, there's a particularly jarring example in the "Bulbmin". They can be found in certain dungeons, and at first appear to be nothing more than dwarf Bulborbs with a single leaf growing out of their back. Then you look up their entry in the [[MonsterCompendium Piklopedia]] after completing the dungeon and discover that the ''actual'' Bulbmin is the leaf itself, a parasitic life form that grafts itself into the bulborb's nervous system through its spinal cord, and controls its actions while the host is still living and conscious.
311*** The Fiery Bulblax is a Bulborb subspecies whose flesh appears to be perpetually drooping and melting from the highly flammable oils in its skin.
312** ''VideoGame/HeyPikmin'': The final boss, [[spoiler:the Leech Hydroe, withers at the end of its first phase before sprouting wings to continue the battle]].
313* ''Franchise/{{Pokemon}}'': At first glance, the franchise doesn't seem to fit this trope since most evolutions occur in the span of 30 seconds, until you realize how drastic the changes of those evolutions are in only the span of 30 seconds. ''Then'' it starts becoming more terrifying. To put it simply, many evolutions involve the sudden introduction of new elemental types, suddenly growing and swelling to sometimes over double the Pokémon's original size, and many evolutions from originally cute creatures suddenly alter their personality into being aggressive and sometimes even disastrously violent.
314** One particularly horrific example is Munchlax's evolution into Snorlax. Munchlax starts as a cute little Pokémon at 2 feet tall and a husky 231.5lbs and ''in the span of 30 seconds'' balloons into a beast that is three times as tall, and over four times as heavy at a half ton in weight!
315** Parasect. An animal being eaten inside out and mind controlled by a parasitic fungus.
316** The red markings on Machoke's biceps and forearms appear to be its skin ripping because its muscles have grown too big too fast for its skin to stretch.
317** Seismitoad. A frog that pops the misshapen orbs and bones in its back so hard it quakes the ground.
318** And then in the real life department, there's some of the animals that the Pokémon are based off of. Once again, Seismitoad.
319** Dusknoir. Yeah, it's a ghost, but still, it has a second mouth. ''On its stomach''.
320** Any Pokémon that gains new limbs upon evolving may count. Apart from the aforementioned Dusknoir (who starts off as a floating head, then gains hands, ''then'' grows arms), Machamp and Graveler are good examples.
321*** Especially Pokémon who form new heads, such as Dugtrio, which are basically three Diglett, Dodrio, which have three heads, and the collection of egg-shaped Pokémon, Exeggcute, forming a single tree with three heads. One has to wonder what it would even be like to share a body with newly grown heads or to merge into one entity.
322*** The Deino line involves one extra head being added with each evolution. In the second form Zweilous, the two heads are not only sentient but implied to be individuals, as they compete over food and leadership. In the final form Hydreigon, there are three heads (two of which act as its ''hands''), but only the central head is sentient, the other two heads being literally brainless and only able to destroy and eat. Either the brains of the two Zweilous heads are merged together upon evolution, or one of its minds is just ''gone''.
323** Ever wondered what a video game glitch would look like in reality? Look no further than Porygon-Z -- essentially an unlicensed [[GameMod software mod]] of [=Porygon2=], with [[FloatingLimbs its limbs, head and neck disconnected from its body]] and its idle animation consisting of convulsing erratically.
324** Heatran's body is made of rugged steel. However, some Pokédex entries state that much of its body has partially melted in spots ''out of its own high body temperature''.
325** The move Shell Smash invokes ShedArmorGainSpeed in a way that's kind of disturbing of thought about too long. It involves the user smashing its own shell for a stat boost, and most of the Pokemon that know it are based on species like turtles and shellfish, which in real life, tend to die when their shell is broken.
326** ''VideoGame/PokemonSwordAndShield'' has its set of Fossil Pokémon, born from the combination of the series's classic prehistoric creature revival system, and the ancient archeological method of mashing incomplete fossils together to make a full "creature". As most of Galar's fossils are missing a lot of parts, you need two to recreate a living Pokémon, and the results are... not pretty. Misshapen, unbalanced, biologically insane (Dracovish most infamously has a dragon ''tail'' for a body, with no explanation on how that even works. It can also only breathe underwater but has a terrestrial animal's legs, meaning it's constantly suffocating as long as it's on land). Arctozolt, the Ice/Electric combination, is so poorly thought out that its head is permanently sick from the low temperatures the Ice-type body generates. Arctovish has its ''head on backwards'', and Dracozolt's upper half is so much thinner than its lower half that its lower half essentially has its inner flesh constantly exposed to the air.
327** Topping Shell Smash above, ''VideoGame/PokemonScarletAndViolet'' introduces Veluza, a fish Pokémon whose signature move, Fillet Away, invokes ShedArmorGainSpeed by doing exactly what it sounds like, ''filleting itself alive''. It's only lessened by the fact that its 'filleted' body isn't particularly graphic and that it has a HealingFactor potent enough that this doesn't inconvenience it.
328* ''VideoGame/{{Portal}}'' features an energy field at the end of most test chambers, called the Aperture Science Material Emancipation Grill, which dissolves any unauthorized material that's carried through it. While this does not include you and your portal device, [=GLaDOS=] is careful to mention that, "on semi-rare occasions", the Grill may emancipate "dental fillings, tooth enamel, and teeth". Yowch.
329* ''VideoGame/Portal2'' ups the ante, all played for BlackComedy.
330** It starts with a CallBack to the first game; when the automated announcer is explaining the purpose of the Emancipation Grill, it mentions that it "may have emancipated the ear tubes inside your head".
331** It also manages Body Horror with purely synthetic entities. The "Frankenturrets" in Chapter 8 are a sadistic mashup of a Weighted Storage Cube and a pair of turrets, which hop around pathetically like a crippled robotic hermit crab and make noises that somehow manage to convey their horror at their own existence. To make it worse, they are intelligent enough to be fried by a LogicBomb.
332** As bad as the synthetic body horrors are, they pale in comparison to the ''implied'' ones you hear about from the pre-recorded messages down in Old Aperture. Seriously, if Cave Johnson felt it important enough to put on a recording, nine times out of ten he's describing the result of some MadScience experiment the test subjects would have just had performed on them, often simply [[ForScience for the sake of science]]. These things include having their urine turned to coal, their blood turned to gasoline, being irradiated to cause tumors to grow, being teleported without their skin, having their bones dissolved, or being [[GeneticEngineeringIsTheNewNuke mutated by praying mantis DNA]]. Science!
333** The Perpetual Testing Initiative adds even more Body Horror, taken to extremes for the sake of BlackComedy. Notable ones include a sentient cloud that can leech off people's skins and Man-Mantises.
334* ''VideoGame/PowerStone'': For as cute and light-hearted as the rest of the game is, the FinalBoss, Final Valgas, would be right at home in ''Franchise/ResidentEvil''; it's a slug-like mass of flesh and crystal, with exposed veins and his normal face melted beyond recognition onto the side of his new face.
335* Villains and protagonist alike of ''VideoGame/{{Prototype}}'' fall into this; the Redlight virus is designed to warp living human flesh into configurations that would be more useful. The protagonist also has the same charming feeding habits as Aptom of ''Manga/{{Guyver}}'': he absorbs beings into himself, preferably ''while'' they're alive, most frequently humans, to heal himself and gain their abilities, their skills, their appearances -- and their memories.
336* ''VideoGame/PsychonautsInTheRhombusOfRuin'' shows that [[spoiler:underneath his shower cap, Dr. Loboto's head is cracked like an eggshell, leaving his brain ''fully exposed''.]]
337* The ''VideoGame/PuellaMagiMadokaMagicaPortable'' game has its own share of Body Horror. For instance, when [[spoiler:Sayaka throws her [[SoulJar soul gem]] away and it lands in Charlottes barrier, leaving her a corpse. If Madoka and Homura are unsuccessful in finding it, Kyouko gets the job done a little too late. Sayaka later wakes up again while Kyouko is sleeping and wanders of by herself. When she makes it home Kyousuke is waiting for her, wanting to give her the song he made for her, only to be absolutely terrified at the sight of her]]. Turns out [[spoiler:Sayaka's body '''''is partly decomposed'''''. And since she doesn't [[FeelNoPain feel pain]] she didn't even notice how '''''half her face has fallen off''''']].
338* ''VideoGame/{{Quake}}'' has a sci-fi variant with the [[AliensAreBastards Strogg]]:
339** ''VideoGame/QuakeII'' enemies include varieties of {{cyborg}} enemies who were roboticized in a gruesome way: the [[https://quake.fandom.com/wiki/Light_Guard_(Q2)?file=Light_2.gif Guards]]' mask seems to be grafted of their faces as there is blood on it, the [[https://quake.fandom.com/wiki/Enforcer_(Q2)?so=search&file=Enforcer.gif Enforcers]]' arms lack skin on their shoulders, the [[https://quake.fandom.com/wiki/Flyer_(Q2)?file=Flyer_2.png Flyers]] are human heads set on heavily weaponed drones, the [[https://quake.fandom.com/wiki/Parasite?so=search&file=Para_2.png Parasites]] are human heads grafted on a cybercanine body who use an OverlyLongTongue [[VampiricDraining to suck out your health]], the [[https://quake.fandom.com/wiki/Brains?so=search&file=Brain_2.png Brains]] only have a camera for a head, giant fleshy stumps for arms, and they attack by deploying tentacles out of their torso, etc.
340** ''VideoGame/QuakeIV'' is positively rife with body horror, from apparently living human chests with computers for heads attached to walls and the Strogg medical facility level, where the player has to watch helplessly -- from first-person perspective, no less -- as Cpl. Matthew Kane gets a painful-looking injection of steroids, has his ''legs cut off with a buzzsaw'' and new cybernetic legs attached as well as a neural implant stabbed into his brain. The fact that you see all of this happen to another prisoner before you (and hear his screams) does not make it any less horrifying, either. Perhaps the most unsettling sight is that of Kane's bloody leg-stumps quivering after his legs have been amputated. The scene (not for the faint of heart) is [[https://www.youtube.com/watch?v=5HH-MqsB8L4 here]] if you want to see it.
341* '''''Much''''' of the ''Franchise/ResidentEvil'' series.
342** The whole function of the T-Virus is to inflict this upon a person. There are multiple occasions, mostly in the case of the Tyrant series, where the virus works too well -- and when the Tyrant is badly damaged, it will trigger secondary mutations resulting in anything between bigger claws, and turning into a murderous blob of teeth and organs.
343** The Keeper's Journal in the first ''VideoGame/ResidentEvil1'' is a long, detailed description of the transformation of a normal person into a zombie. It runs from the initial outbreak at the Umbrella Arkley Lab, to the Keeper noticing strange sores appearing all over his body, to him scratching off a chunk of rotting flesh from his own arm and finding himself mysteriously hungry.
344--->''"[[ApocalypticLog Itchy. Tasty.]]"''
345** The ChestBurster in ''VideoGame/ResidentEvil2'', and needless to say, William Birkin's mutations.
346** The titular character in ''VideoGame/ResidentEvil3Nemesis'', [[ImplacableMan Nemesis]], is more or less a heavily modified version of Mr.X from the previous game and undergoes this process severely throughout the latter half of the game.
347** Don't forget Dr. James Marcus' transformation into a queen leech in ''VideoGame/ResidentEvil0''.
348** Nosferatu, the [[TragicMonster tragic mutation]] of Alexander Ashford in ''VideoGame/ResidentEvilCodeVeronica''.
349** ''VideoGame/ResidentEvil4'' plays this with Las Plagas (''"The Pests"'' in Spanish), some sort of strange being that [[PuppeteerParasite takes over the host's body and submits their will and mind to Saddler's own purposes]]. As you play the game, you can see how Las Plagas are slowly taking over the bodies of Leon and Ashley.
350** ''VideoGame/ResidentEvil5'' has Uroboros. Some of the Majini mutate into nastier forms after doing a certain amount of damage to them, similr to popping off the head of a Los Ganados from ''[=RE4=]'' ("the cow" or "the herd" in Spanish).
351** ''VideoGame/ResidentEvilRevelations'' might just top all of these with a specific mutation caused by the T-Abyss virus; the Scagdead. Not only is the actual mutation very nasty, but the actual progression is worse; the host is never actually ''killed'' by the virus and then resurrected, no; they ''are still alive and conscious'' for the duration of the infection. And that happens when you're ''resistant'' to the virus.
352** And finally, the C-Virus from ''VideoGame/ResidentEvil6''.
353** ''VideoGame/ResidentEvil7Biohazard'' has a whole new brand of nastiness with [[FesteringFungus the "Mold"]], a fungal superorganism that transforms its victims, in most cases, into walking masses of gunk. [[spoiler:And that's before getting into the risk of falling under mind control!]]
354* ''VideoGame/{{Resistance}}'':
355** The Chimeras will happily mutate anyone into becoming one of them, wrap in cocoons and becoming freaks of nature. Daedalus was once a human...
356** ''Resistance 3'' allows the player to inflict this trope on enemies with the [[http://resistance.wikia.com/wiki/Mutator Mutator]], a gun that causes its target to sprout explosive pustules.
357* ''VideoGame/RiskOfRain'' has this in droves. It's heavilly implied that the player character is doing this to himself just to survive. For instance, imagine killing a giant magma worm. Upon inspection, it turns out its eyes are symbiotic creatures, providing the creature sight and the worm provides protection. The player character, in his SanitySlippage, decides to rip out his own eye and replace it with these. In fact, it gets to a point where your character is deemed no-longer human, and in the case of the robot, is merging with the flesh with its robotic hull as a skeleton. Not to mention the engineer who is implied to have merged with the ship itself. The only one that is not subject to this is the Acrid, but they were already a test subject.
358* ''VideoGame/ScottPilgrimVsTheWorldTheGame'' has an homage to the Akira example on the Anime page. In the boss fight with Todd Ingram, one of his attacks involves jumping to one side of the screen as his arm mutates, then thrusting his arm at you as it turns into a gigantic writhing mass of fangs and tentacles. However, since Todd's power is derived from his veganism, the arm also contains mutated versions of various ''vegetables''. It might make it worse that Todd has a SlasherSmile during the whole attack.
359* In ''VideoGame/ScurgeHive'', you play as a Samus-like space-age bounty hunter named Jenosa Arma, who must make her way through an infested research facility. The entire game, she's infected with an alien virus that slowly takes over her body (represented as a percentage). You need to keep visiting decontamination centers to get the infection rate back down, but it will never disappear completely. If Jenosa's infection rate reaches 100%, you'll get to watch as she dies, mutates into an alien, gets up, and howls. It's tiny and pixelated, being on the Gameboy Advance, but it's probably the most disturbing and horrifying way to die in the game.
360* ''VideoGame/TheSecretWorld''
361** The Draug of Solomon Island. Essentially [[FishPeople fishmen zombies]], they're a ghastly blend of dead human flesh and fishy components, including tentacles, crab claws, and even coral... but all that pales into insignificance next to the way these things ''breed.'' Basically, after killing everyone in the area, they resurrect them as zombies; the Draug sea-witches implant some of them with eggs delivered from [[ExoticEquipment long tentacles]], causing the infected zombies to swell up into hideous walking incubators, who then wander until they can find a safe patch of beach on which to plant themselves. Once they've done so, they bloat and transform into huge squishy cocoons, and once they've had enough time to grow, the pod opens to reveal a new draug. Urk.
362** It's still possible for living humans to be converted into the Draug, as was the case with the unfortunate Joe Slater. [[spoiler:Having been directly exposed to the polluted seas around the Isle of Dead Ships, he's been infected with a dose of the original Filth strain that transformed the first Viking converts; by the time you catch up with him, his left arm has been distorted into massive club of bone and coral, his right arm is covered in wriggling tentacles, and his face is pockmarked with what look like barnacles. According to the Buzzing, his internal organs are being taken over by various species of coral, and forms of sea life are living in his body cavities. Plus, judging by the VaderBreath, he's having trouble breathing on dry land.]]
363** The Filth. Dear god, the Filth. Quite apart from being a MysticalPlague derived from the thoughts of {{Eldritch Abomination}}s, the symptoms are nowhere near as simple as the tarry skin and writhing tentacles you commonly see in most infectees: Dr. Klein and Dr. Schreber have been exposed so long that their bones and skulls are stretching out of shape -- the latter looking like a monstrous parody of a gorilla, the former looking like someone tried to crossbreed a human with a [[Film/{{Alien}} Xenomorph]], [[spoiler:probably because he's been injecting the Filth directly into his brain]]. Once again, the Buzzing brings home the goods on other cases, in one case involving a woman covers in boils that explode to reveal new eyes, and another involving a trucker who carved alien runes onto his face, resulting in his head "blossoming into a bouquet of lampreys".
364** Feeling short of breath in the {{Hell}} Dimensions? Don't worry! It's just ''your blood oxidizing and turning to metal in your veins!''
365** The Rakshasa are hideously pitiable already, what with all the thorny bindings worked through their flesh and over their eyes... but then you meet the Machine Tyrants -- an entire group of Rakshasa [[FusionDance fused into a single giant multi-headed monstrosity]].
366** The experiments at the Nursery. Dr. Schreber managed to make use of some of the most dangerous phenomena in the Secret World and apply them to ''children.'' There's Filth exposure; there's [[FesteringFungus parasitic fungi]]; there's [[TransformationOfThePossessed demonic possession]]; there's the attempt to make child-lycanthropes into monsters who can transform into ''anything'' -- and the giant misshapen [[ComicBook/TheIncredibleHulk Hulk]]-like ''thing'' haunting the forest as a result... and when one of the mutilated kids comes shambling up to [[spoiler:Lilith]] for a hug, you'd be forgiven for wondering if the ensuing NeckSnap counts as a KickTheDog moment or a MercyKill.
367** A comparatively mundane example crops up in one of the Halloween 2014 stories, in which a vain woman disfigured by smallpox pesters a Wabanaki shaman for a cure. Having lost his entire family to the same outbreak, the shaman is not pleased at being bothered in his time of mourning -- but gives the woman an ointment that he promises will [[ExactWords make her skin smooth]] again. And after applying it to her body, the woman finds too late that the ointment was decidedly acidic. But hey, at least it smoothed out her skin... ''right before the whole thing sloughed off''.
368* An unintentional example comes from ''[[VideoGame/SegaSuperstars Sonic & All-Stars Racing Transformed]]''. Switching to front view upon being [[XRaySparks electrocuted]] by something reveals that the characters' skulls are completely blank (there aren't any eye sockets, nose sockets, or teeth), they have no finger bones, and only three toes per foot. Granted, the characters' skeletons were obviously sloppily designed because the developers figured that they shouldn't waste hundreds to thousands of polygons on something you'll only see for a few frames, but ''still''!
369* In ''VideoGame/TheSexyBrutale'', the Bloody Girl has no skin, and her hair is a fountain of blood.
370* ''Franchise/ShinMegamiTensei''
371** Isamu in ''VideoGame/ShinMegamiTenseiIIINocturne'' starts of as being a completely normal fellow, but as he spends time in the Amala Network, the emotions of people who died in the Conception begin to cling to him, taking the form of screaming faces covering his upper body. The fact that he stops wearing his shirt afterwards does not help ''at all''. He keeps his hat, though. On the other hand, Chiaki replaces her missing arm with a roiling mass of tentacles roughly hewn in the shape of an arm. The problem is said tentacles are connected to her body all the way to her face. She eventually ditches the arm in favor of a nicer form. Hikawa instead is connected by several organic tubes from the waist down to his god.
372** From pretty much every game in the franchise, Fusion Errors are kicked in here by dint of FridgeHorror. How else do you call a ''failed'' FusionDance?
373** Speaking of failed fusions, in ''VideoGame/ShinMegamiTenseiIV'', [[spoiler:in a certain room in Camp Ichigaya in Infernal Tokyo, you see a couple of demons talking to each other and find out that one of them is a failed result of making a Demonoid, resulting in a low tier demon that is irreversible. Also, during the endgame, Walter fuses with Lucifer to help the later regain his full powers. In the Neutral and Law paths, during the second part of the fight with him, his left gauntlet breaks off revealing that Walter's body had not completely sublimated into Lucifer, leaving a twitching, fetus-like tumor]].
374* ''VideoGame/{{Shadowman}}'' takes place in Deadside, where all souls are sent upon death. It has plentiful examples of body horror.
375** The enemies demonstrate how a person's soul degrades after death. At best you turn into a moaning pale rendition of Fat Bastard post-lipo suction; at worst you grow an extra head and lose your legs, develop hooks for hands and grow a gas mask fused into your face; etcetera.
376** The most disturbing level in the game is the Playrooms, where the "playrooms" are dungeons with blood-soaked floors, piles of torn human flesh, and the hook-handed enemies mentioned above. Really made into nightmare fuel by the children's lullaby music that plays during the level.
377** Huts and bridges are made out of sewn together sheets of human flesh.
378** You follow the game's five serial killers by using schism traces- special portals leading to the land of the living. A schism trace is a human body crucified, missing its parts from the waist down, and with all internal organs removed. You open the trace by using an item called a retractor, which rips and holds the body's ribcage open. Jack's diary details the traces, and implies that each body is ''still alive''
379* ''Franchise/SilentHill'':
380** ''VideoGame/SilentHill1'': Doctors, Nurses and [[spoiler:Cybil, when you have to fight her in the Amusement Park]] have all been taken over by some manner of PuppeteerParasite, but the former two have hideous fleshy growths on their backs, resembling massive tumors. Oh, and unlike other monsters in the franchise, they are heavily implied to be real people dragged into the Otherworld and repurposed by Alessa, as opposed to apparitions or creations of Silent Hill made whole cloth.
381** ''VideoGame/SilentHill3'':
382*** Heather turns out to be [[spoiler:"pregnant" with a freakish demon which she is supposed to give birth to]].
383*** Many of the monsters, especially in 3 and ''Homecoming'', are quite body-horrific, e.g. the Bubble Head Nurses, the Abstract Daddy, the Pendulums, the Siam, and the centipede made of human torsoes.
384%% ** The scene where the demon is exorcised from Alessa in the good ending of ''[[VideoGame/SilentHill1 1]]''.
385* In the Nintendo 64 game ''VideoGame/SinAndPunishment'', the main character Saki is transformed into an enormous, mindless bioweapon looking like something out of ''Anime/NeonGenesisEvangelion''. It's apparently caused by a cascade of blood that inexplicably washes over Tokyo. Eventually he regains his human form, somewhat.
386%% * ''VideoGame/SirenGames'' is rife with examples of this.
387* ''VideoGame/{{Skullgirls}}'' has body horror in spades. Where do you even begin...?
388** Probably the most infamous example is Double: a seemingly normal nun who ''literally turns inside out'' to reveal her true form, a monster who has the appearance of a constantly-shifting mass of flesh and organs.
389** Then there's Painwheel, a girl who was kidnapped from a normal life and used as a subject in secretive and unethical living weapons experiments. Her blood was replaced with that of a Skullgirl, the game's titular monstrous entities. Her body was implanted with the Gae Bolga parasite, which manifest as spikes that burst through her skin, and the helicopter blade-like Buer Drive was installed in her back. She is constantly aching, and every attack she does causes her to scream in pain.
390** Next up is Peacock, a demented little cyborg girl who looks like she walked out of a twisted old cartoon. Peacock is a bit more subtle, in part due to the nature of her attacks and the humor of her character, but the body horror is definitely there. See those [[BlackBeadEyes cartoon eyes]]? Those are empty sockets. Her arms, legs, and teeth were all ripped out during the same incident, and were replaced with cyborg parts when a kindly scientist rescued her. She now sees through the eyes on her arms, the Argus system, which give her a decidedly creepy appearance.
391** Miss Fortune is a CatGirl bandit who swallowed an immortality-granting gem after a heist gone wrong and was cut into pieces by the group she stole it from. The gem kept her alive even still, allowing her to pull herself back together. At first glance she's not too bad if you ignore the fact that the bones at her joints and the tips of her toes are showing, but her fighting style revolves around tearing herself into pieces (her main gimmick even being keeping her head separated to pull off combos) and her combat involves copious amounts of HighPressureBlood and using her detached body part in bizarre ways, her grab even has her wrap the enemy in a yarn ball made out of her own muscle fiber.
392** Eliza, outwardly an impossibly beautiful woman, is just a consciousness and a human skin hiding a skeleton made out of the serpentine parasite Sehkmet. Several of her animations have her doing things that are just wrong. Her pushback animation is probably the worst, as Sehkmet bursts out of her skin entirely, and you can see that a pair of beetles are holding her eyes.
393* Dark Gaia's OneWingedAngel-form from ''Videogame/SonicUnleashed'' is probably the goriest thing ever shown in a ''Franchise/{{Sonic|TheHedgehog}}'' game. [[spoiler:Its jaw splits across its entire head as it roars loudly. It grows two extra pairs of arms, which burst out of its sides with audible cracks and ''lots'' of AlienBlood. It gains seven more eyes, [[EyesDoNotBelongThere which are all positioned in its mouth]] and surrounded by ''way'' too many tongues.]] All of this is shown in [[{{Squick}} very gross]] detail.
394* Despite ''VideoGame/SpaceQuest'' being a comedy series, ''VideoGame/{{Space Quest IV|Roger Wilco and the Time Rippers}}'' has a terrifying one with the "modified" survivor on Xenon's blighted surface. Wandering in a daze, yellowed skin, clothed in rags, headgear that forces the eyes to never shut, and only able to utter screams. ''VideoGame/{{Space Quest V|The Next Mutation}}'' also has the effects of the Primordial Soup -- victims literally erupting in pus-filled boils and their bodies melting into unrecognizable piles of goo if left untreated.
395* ''VisualNovel/SpiritHunter'':
396** All of the spirits in both ''VisualNovel/SpiritHunterDeathMark'' and ''VisualNovel/SpiritHunterNG'' have been hideously warped from their previous humas forms -- while most of them still look {{humanoid|Abomination}}, they often have warped, disproportionate limbs and/or non-human traits like arm whips, animal teeth, etc.
397** The only way to describe Yakumo's corpse once Akira finds it in ''NG''. Multiple arms are stitched onto his body, his jaw is torn nearly in two, and the whole thing is covered in rot and maggots, making the whole thing nearly impossible to register as a human body. The worst part is that the arms were stapled onto him ''by himself''.
398* The ''VideoGame/{{Splatterhouse}}'' series holds two examples, both using the same character: [[spoiler:Jennifer, Rick's girlfriend]]. In the first game in the series, [[spoiler:Jennifer]] turns into a monster when you least expect it -- right after [[spoiler:you believe you've saved her]]. In the third game, [[spoiler:Jennifer]] is infected by a Boreworm, and your performance in the first couple of levels determines [[spoiler:whether you save her or whether she becomes another monster you have to kill]].
399** [[spoiler:"Rick, I'M DYING!"/"Help...me..."]]
400** ''Splatterhouse'' in the remake is rife with this trope. Rick ShowsDamage by having his body mutilated; losing chunks of flesh and exposing bone and internal organs. Not to mention his LovecraftianSuperpower, or that he was practically split in half by the monster at the beginning of the game, resulting in the Terror Mask messily and painfully putting him back together.
401* ''VideoGame/Splatoon2'': In ''Octo Expansion'', test subjects who pass all the tests in the deepsea metro are souped up in a blender. Alive. Their remains are then applied to test subjects who have failed, causing them to become Sanitised -- in a [[ZombieInfectee zombie-like state]] and able to be mind-controlled, while having no memories.
402* ''Franchise/StarCraft'':
403** The Zerg can "infest" a Terran by infecting him or her with the hyper-evolutionary virus, which turns that Terran into [[http://starcraft.wikia.com/wiki/Infested_terran this]]. With the exception of Lieutenant Sarah Kerrigan and a few others, most infested terrans are deemed next to worthless by the Swarm, and as such are made to be ticking time bombs or cannon fodder. Infestation is generally considered a FateWorseThanDeath; an infested civilian is heard begging for a MercyKill in the ''Wings of Liberty'' mission "Outbreak", and [[ChaoticEvil Kerrigan]] threatens Raynor in "The Gates of Hell" with infestation instead of death.
404--->'''Kerrigan''': Do you think death is the worst thing that can happen to you here? Infestation is what's coming for you. Soon all will serve the Swarm!
405** In [[VideoGame/StarCraftI the first game]], the Zerg Queen can also produce Broodlings, spores that will consume any biological matter (read: living human or Protoss) before exploding out of their incubator, instantly killing said unit.
406* In ''VideoGame/StarFoxAssault'', Pigma undergoes [[spoiler:a horrific transformation at the hands of the Aparoids, in which he is assimilated into a spacecraft, turning his whole body into a giant, mutilated, vaguely cybernetic (but mostly organic-looking) pig's face, kept safe in a metallic cube which can open and close, hiding or revealing said face]]. He then later shows up in ''Command'' in an alternate, still pretty weird form -- but fortunately, it's much less creepy (and [[AntiClimaxBoss easier to defeat]]).
407* ''VideoGame/{{Strangeland}}'' is home to many horrific creatures that look Frankensteined together from other creatures. [[spoiler:The Streammaid is one such example, being a mermaid pieced together from other living humans.]]
408* ''VideoGame/{{Struggling}}'' is chock-full of this. For starters, the protagonist is a pair of conjoined heads with arms.
409* ''VideoGame/TheSuffering'' has quite a bit of this, especially as the enemies are all personifications of different methods of execution: The Festers, for example, represent those left to die aboard a beached slave ship, and are constantly being eaten from within by rats. Occasionally, these bloated corpses will ''open'' their bellies and let a swarm of live rats pour out to attack anyone in the area.
410** Mainliners (representing lethal injection) are in constant pain due to all the lethal chemicals in their veins- as if the stunted limbs and [[EyeScream syringed eyeballs]] weren't bad enough.
411** Torque's transformation into his [[SuperpoweredEvilSide monster form]] in which his head appears to briefly turn inside out and [[EyelessFace his eyes vanish behind skin]]. In the sequel, the transformations are more intense, depending on how far down the KarmaMeter Torque is. The worst involves Torque's skin hardening into bony plates covered in sharp spines.
412** At one point in the sequel, a guard is briefly heard screaming over the radio about being sliced in the stomach and that something is "pulling itself inside" him.
413** The Creeper's weapons of choice, namely the bodies of his prostitute victims, bonded to his stomach and made into CombatTentacles. Oh, and apparently, being absorbed by this guy is the [[FateWorseThanDeath fate of any woman in the game he doesn't decide to gut immediately]].
414** And the Festers? According to their entry in Clem's journal they might actually be [[spoiler:the spirit of the slave-traders as opposed to the slaves they left to die on the ship]].
415* The true form of Mimi from ''VideoGame/SuperPaperMario'' deserves an honorable mention -- if she weren't done in a cartoony art-style loosely inspired by NES games, the appearance of a little girl with a bizarrely-warped, upside-down head with spider legs coming out of it, and her now limp and useless body dangling below her in a parody of ''Film/TheThing1982'' would be Grade-A horror itself, and it still manages to be creepy even with that art style. Her ''Film/TheExorcist''-esque transformation sequence, in which she breaks her own neck (with an audible CRACK), doesn't help much.
416* Some of the bosses of ''VideoGame/SurvivalCrisisZ'' are this, including a giant zombie covered in mutant maggots and an Infected with ''spider limbs for a head.''
417* The annelid Hybrids, and ''anything'' to do with [[TheVirus The Many]] from ''VideoGame/SystemShock2''. Imagine a mind-controlling alien parasitic worm that assimilates you into its HiveMind. Now imagine that worm '''''burrowed into your skull and chest''''', and that the infection can also mutate you into a monster that doesn't even ''vaguely'' resemble humanity anymore. Hearing the [[ApocalypticLog audio logs]] of the crew members that fell under the control of The Many, documenting their slow transformation (often without them even realizing what's happening to them) is one of the most terrifying parts of the game.
418* ''VideoGame/{{Thief}}'':
419** ''VideoGame/ThiefIITheMetalAge'' gives us the Servants. The look like cleverly built humanoid robots and are sold as such to the City's nobility. Underneath the masks and suits are mutilated vagrants, prostitutes, and others deemed as 'scum' by the villains, forced into servitude by their mechanical masks -- you can hear them sobbing and whimpering to themselves. Their existence is so horrific that some of them thank you as they die. Related is the necrotic mutox, also called Rust Gas. It reduces any organic material it touches to something resembling rust, and it will grow until it runs out of organic matter to consume. You never actually witness its effects on a living person... but you do hear them...
420** ''VideoGame/ThiefDeadlyShadows'':
421*** The game offers [[spoiler:the Hag]] as its BigBad. You learn fairly early on there's something acting as a bogeyman in the City, reputedly having murdered people (leaving variously mutilated corpses behind, sometimes only blood stains). Near the end of the game, you encounter the unusual ghost of one victim, a soul with no human appearance (only a bauble of light). When you lay her ghost to rest by restoring her human-shape, you inadvertently unmask the monster: [[spoiler:the Hag, an ancient woman who learned to lengthen her own lifespan by murdering people and ''wear the flayed skins of her victims as disguises''. Her real form is now a tumorous mass of faces, hands, teeth and flesh that move independent of her control.]]
422*** There are also the remains of the former inmates of the orphanage that was also an insane asylum (simultaneously). They're mummified corpses -- but when alive, their hands and heads were locked in wire cages to keep them from harming themselves or anyone else. Now that they're dead, the alien consciousness of the institution puppets them in a freakish, twitching parody of their old lives even as they rot.
423** The 2014 reboot of Thief has the Freaks, once human creatures corrupted by the Primal into grotesque abominations.
424* Used quite a bit in the ''Franchise/TombRaider'' series, but ''Tomb Raider III'' especially loves this.
425** The Damned, a group of hooded, masked men who lurk underground, have, thanks to Sophia's experiments, been left with their flesh constantly rotting -- [[AFateWorseThanDeath and immortal, as they discovered when none of their suicide attempts worked]].
426** The RX-Tech mine workers have mutated into hideous (and violent) creatures due to the energies from the meteorite. They are among the most unsettling enemies in the game. Then there's [[spoiler:Dr. Willard]]'s boss form...
427** ''The Angel of Darkness'' also features this in [[spoiler:Boaz]]'s case.
428** It is implied that this is the fate of some of the Monstrum's victims. In the case of [[spoiler:one of Bouchard's cronies]] we get to see the results first-hand. Half of his body is a giant, burnt, swollen mess. [[AndIMustScream And he's somehow still alive.]]
429* ''VideoGame/TraumaCenterAtlus'':
430** Every game in the series has an infection/virus/whatever ripping people's organs, draining them, digging through hearts, creating reproducing tumors that put bunnies in heat to shame, etc.
431** A subtle example, since it only becomes this when you do some outside research: the villain of ''New Blood'' has a condition he refers to as "malignant diencephalic sclerosis". "Malignant" means it's spreading, "diencephalic" means both halves of the brain, "sclerosis" is hardening of tissue... oh, dear God, ''his brain is petrifying!'' [[spoiler:The Cardia Stigma acts as an antagonist to the condition, but once you destroy it, he dies in under half an hour.]]
432* In ''VideoGame/TronTwoPointOh'', a User digitized without the necessary safety features or correction algorithms becomes ''horribly'' twisted. Thorne is more or less a living computer virus, and the trio of F-Con execs who decide to take matters into their own hands end up fused into a single, three-headed creature of mix and match parts.
433* ''VideoGame/{{Undertale}}'' has the Amalgamates, [[spoiler:which are Alphys' attempts at giving monsters human Determination, which made them melt and merge into each other]]. Such lovely examples include [[spoiler:a snowdrake with ''[[EyeScream vegetoid faces for eyes]]'' and a giant blob which are multiple dogs merged into one, with a gaping and leaking black hole where its face would be. The Amalgamates ''also'' count towards those spared towards the pacifist ending. Why? Because unlike 90% of the tropes in this page, they're not deranged, demented, bloodthirsty creatures, first-appearances notwithstanding. Give them a chance to try and communicate with you, and you'll see how friendly they can be. For example, the aforementioned dog blob still thinks like every other dog monster encountered so far, and simply wants to play with you.]]
434* In the surreal Russian game ''[[VideoGame/{{Turgor}} The Void]]'', the cast of beautiful, naked and uncensored "sisters" are complemented by the absolutely horrifying, disgusting flesh and metal abomination "brothers". 'Mantid', as one example, is a quadruple amputee who has various rusted metal protrusions sticking out of him haphazardly, two of which he uses to walk around on as giant, twisted stilts. It is far worse then it sounds.
435* In ''VideoGame/ValkyrieProfile'', a young princess is force-fed a poison called "Ghoul Powder", which transforms her into a demon and causes her to kill three soldiers. The worst part is that when she's killing one of the soldiers mid-transformation, her innocent, conscious mind is ''still aware''. [[https://www.youtube.com/watch?v=LMSOpe3aXUE Not for the easily squeamish]].
436* ''VideoGame/VampireTheMasqueradeBloodlines'':
437** The fleshcrafting Tzimisce vampire clan get their share of creeps. [[spoiler:First, you find a snuff film in which a woman is torn to pieces by what look like demonic heads with arms for legs. Then you find the house where it was filmed, only to find out the thing is wall-papered in flesh. Then you go into the basement, where you fight the Tzimisce responsible, who summons more of the head things and turns into blood. Then, you have to fight your way through the sewers, where an even worse Tzimisce experiment awaits -- giant spider-like ''things'' made from the torsos of three women]].
438** Ming Xiao, the head of the Los Angeles [[OurVampiresAreDifferent Kuei-Jin]], [[spoiler:turns into a huge red blob with tentacles and then proceeds to beat the shit out of you]].
439* ''VisualNovel/VirtuesLastReward'':
440** Throughout the game, [[spoiler:Sigma eventually learns that ''some'' part of his body is inhuman, with an appropriately horrified and startled reaction. It is later revealed that he lost both of his arms and his left eye during [[VisualNovel/ZeroTimeDilemma the Nevada test site incident]]... the results of which are seen in the game's epilogue. It's not pretty.]]
441** In Luna's ending, [[spoiler:Luna reveals that she is a RidiculouslyHumanRobot whose appearance is constructed with an artificial tissue called ABT. Due to Clover injecting her with tubocurarine (a muscle relaxant) some time earlier, as she hugs Sigma her ''entire face'' begins to melt off...]]
442* ''VideoGame/WarcraftIIIReignOfChaos'':
443** Everything associated with the Undead is horrible, one example that doesn't start to cover it is how Necromancers (and Rods of Necromancy) raise two Skeletal Warriors [[FridgeHorror from one body.]] The aptly-named Abominations, which are monstrosities made entirely out of random anonymous stitched-together body parts (who, by the way, get consciousnesses of their own), all have gaping holes in their chests, leaving their stomachs hanging wide open for everybody to see. Or, whatever else is in there, at least...
444** From ''The Frozen Throne'', the Crypt Lord can create, from just about any body, some kind of ''giant beetle''.
445* ''VideoGame/Waxworks1992'': One of the levels is a mineshaft overran with plant mutants. Getting killed by one of these will result in a [[NauseaFuel very nasty]] [[HaveANiceDeath game over screen]].
446* ''VisualNovel/WeKnowTheDevil'': Whoever is possessed by the devil becomes a HumanoidAbomination displaying their particular BodyMotif: Jupiter has countless arms, Venus is covered in feathers and eyes, and Neptune spews bile. Is present but downplayed in [[GoldenEnding the True Ending.]]
447* ''VideoGame/WerewolfTheApocalypseEarthblood'': Bane possession horrifically disfigures its victims -- the fomori that Cahal fights possess features such as distended throats and stomachs filled with bile, swollen heads covered in eyes, and spongy, hole-filled flesh capable of extruding tangled masses of spiny tendrils.
448* ''VideoGame/{{Wick}}'' features a boy who's contorted from polio.
449* ''VideoGame/WildStar'': The Eldan were very, very keen on doing all sorts of horrible things to organisms to advance their own purposes. A prime example would be Metal Maw, the "giant robot-fish thing with the laser" in Deradune.
450* ''VideoGame/{{Wobbledogs}}'': The genetic nightmares you can inflict on your Wobbledogs can be pretty intense for a game with such simple, cute graphics. Repeatedly mashing dogs together in the breeding simulator can lead, given enough iterations, to extra or missing legs, too many eyes, bodies warped into wedge shapes instead of rectangles, multi-headed creatures on long, spindly legs, and [[https://static.wikia.nocookie.net/wobbledogs/images/8/8d/AN_wobble_dog_with_alot_of_wings.png/revision/latest?cb=20220901004540 this thing]], with what even the wiki describes as what "might be too many wings". There are even achievements for successfully breeding a Wobbledog with no legs and raising it to adulthood despite its inability to walk, and for spawning Wobbledogs with specific deformities like a specific missing leg or only one wing (which somehow still allows it to fly).
451* ''VideoGame/WorldOfHorror'' has body horror in spades, wearing its inspiration from Creator/JunjiIto on its sleeve. Among the myriad examples you may encounter are a corpse reanimated by a mutant fungus, a mangle of human body parts from a school group who died at sea fused together, and a woman whose face is missing, leaving a gaping hole lined with rib-like bone protrusions. And your player character may suffer a number of dreadful conditions, ranging from gruesome but otherwise ordinary injuries like broken bones and flesh wounds to [[GlasgowGrin getting their mouth split open]] by a scissor-wielding ghost to suffering a curse that causes mysterious holes to appear in their flesh.
452* ''VideoGame/WorldOfWarcraft'':
453** In the in-game cinematic for ''The Wrathgate'', a glimpse of what the plague does is seen as an NPC is briefly seen on his knees clutching his head through his helmet because ''his face is melting''.
454** The Curse of Flesh is this from the perspective of everyone not already afflicted with it. Trustworthy, enduring metal being replaced with easily corruptible flesh by the will of an EldritchAbomination, an ever-dying, malfunctioning travesty of one's intended self. The horror tends to be lost on players, since it already turned them into, among others, humans. The Curse can be reversed, at least for limited numbers of people. ''They remember their former lives afterwards.''
455** The Worgen transformation sequence may constitute BodyHorror for some players (the character, starting as human, stares in apparent horror as his limbs turn wolflike, then screams and holds his head as the rest of him transforms).
456** The raid boss Razorscale may be considered this, although unless you did several quests in The Storm Peaks it may be lost on you. The [[OurDragonsAreDifferent Proto-Dragon]] Veranus was captured by Loken. Then Loken fused metal plates completely across her body and, judging from her model, completely replaced several parts of her body to create a [[NinjaPirateZombieRobot "Plated Dragon"]].
457** Similar to Razorscale, Deathwing has been artificially covered with metal plates while in hiding. In this case, however, it's to prevent his molten lava interior from just spraying out everywhere. Once you finally face him in battle, it quickly becomes clear that Deathwing is in no real way a dragon any longer. He's become a DraconicAbomination.
458** The Forsaken. We're talking about, essentially, intelligent zombies with free will. Since they ''are'' zombies, they can eat (certain types of) fallen enemies. Background lore reveals that Forsaken who utilize the Light extensively start to regain some of their lost senses. Some are driven to suicide because this results in them smelling their own rot, tasting their decaying flesh, and feeling the maggots in their body.
459* ''VideoGame/XCom'':
460** ''VideoGame/XCOMUFODefense'' had the infamous Chrysalids, insect-like humanoid aliens who could turn any X-Com soldier or civilian into a bulging, misshapen zombie with a single egg-injecting melee attack. The zombies are essentially still-living meat-suits for the juvenile Chrysalids, who erupt out of the zombies like someone popping out of a too-small shirt after the zombie takes too much damage.
461** ''VideoGame/XCOMTerrorFromTheDeep'':
462*** The Tentaculats essentially do the same thing as Chrysalids by transforming the human victims it captures into more alien Tentaculats.
463*** The things the Aliens are implied to visit upon capturing humans. The lucky ones are turned into alien food or dissected, while the unlucky ones...well, the Bio-Drone from ''Terror from the Deep'' is a brain in a vat with an anti-gravity base and a sonic weapon, controlled by implanted alien electronics. The Bio-Drone's sonic weapon was built out of the original human's vocal chords which it uses to scream its victims to death.
464*** ''[=TftD=]'' features a creature called the "Deep One", which is essentially a living human-turned-alien-incubator. The description of a device called alien implanter reads: ''"...this [removal/addition of organs and electronics] was thought to be done to unconscious subjects, but research suggests that the subject is conscious and painfully aware. The human physiology fits this device unfortunately well."''
465** Some of the critters from ''VideoGame/UFOAftermath'' look equally unpleasant, like Cudgels and Dangleflies. Car Crabs, on the other hand, are awesome.
466* In ''VideoGame/{{Xenonauts}}'', the game over screen tells you that what humans survived the alien attacks were modified into unrecognisable forms.
467* ''VideoGame/{{Xenogears}}'' has the moment when [[spoiler:Krelian turns ''half the human race'' into Wels, horribly mutated humans that act as spare parts for the BigBad of the game]]. Then the Gazel Ministry get in on the act and [[spoiler:activate the Gaetia Key, dooming most of what's left to the same fate.]]
468* In ''VideoGame/XenobladeChronicles1'', the [[spoiler:High Entia]] are subjected to a similar fate as the humans in ''VideoGame/{{Xenogears}}'' when [[spoiler:Zanza]] exposes them to high levels of ether, triggering the genes that cause them to degenerate back into their primordial form of [[spoiler:Telethia]].
469* In ''VideoGame/XenobladeChroniclesX'', the Chimera family of enemies all qualify, possessing additional (And often misplaced) eyes, tails, and/or heads of various animals, due to being the products of the malfunctioning Lifehold Core's security system. Their parts don't exactly function how one might expect, either, with the Soldier Chimeras for instance, appearing to have a fairly ordinary head reminiscent of a monitor lizard's...which proceeds to split open vertically all the way to the base of the neck once they're provoked, leaving their forked tongues hanging out. The FinalBoss is a much bigger humanoid Chimera, which has a head with no jaw, a big single eye on its right shoulder, and a bunch of animal heads all over its right arm.
470* In ''VideoGame/XenobladeChronicles2'', attempts at crossing humans with [[LivingWeapon Blades]] run the risk of this from both directions. The early Blade Eater prototypes, humans infused with the Core Crystals from Blades, mutated into demons with exposed muscles and NestedMouths, while the residents of the Land of Morytha that tried to replace their brain matter with Core Crystals wound up turning into even more grotesque monsters. It's implied that many of these mutant Blade Eaters were created before the process was perfected, with modern Blade Eaters suffering none of the body horror of the previous models. [[spoiler:Unless they gorge themselves on Core Crystals, which Amalthus does to assume his OneWingedAngel form, turning into a form that's far more elegant than the prototypes, but still a hulking monstrosity.]] Blades infused with human flesh, Flesh Eaters, run the risk of either losing their powers or elevating them to SuperpowerLottery levels: in the case of a Healer Blade who got the latter result, they can "heal" someone so much that it induces a fast-acting cancer which inflates the victim's limbs like balloons.
471* In ''VideoGame/XenobladeChronicles3'', Moebius O and P are quite proud of their Interlink combination, declaring it perfect despite how obviously flawed it is: their combined form has four arms, two heads, and tiny legs with a massive upper body.
472* In ''VideoGame/YumeNikki'', Madotsuki can stumble upon a little girl named Monoko wandering in a tunnel in the White Desert. Seems relatively normal, right? If Madotsuki flashes the Stoplight ability at her, however, Monoko instantly turns into a five-armed freak of nature (one of those arms is ''coming out of her head!'') with what appears to be a melting eye and some sort of ''vortex'' in her stomach.
473%% Please leave as last example!
474* On a related note, the texture maps for almost every 3D character are pretty grotesque when taken out of context. They're sort of...flattened out pieces of people, all stretched.

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