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* A curious example in ''[[WebAnimation/RedVsBlueTheRecollection Red vs. Blue: Reconstruction]]'' - when an [=AI=] is implanted in a character, the effect is described as being "of the same mind", where the two entities share thoughts. Though the host is usually able to maintain his or her identity (even if free will is lost), Agent Maine (better known as [[TheJuggernaut the Meta]]) degenerated into a mindless husk after playing host to 7 different [=AI=]s ''at once'' and stayed that way even when the [=AI=]s were removed. Of particular note is the fact that all 7 [=AI=]s were {{Literal Split Personalit|y}}ies of another [=AI=], the Alpha.

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* A curious example in ''[[WebAnimation/RedVsBlueTheRecollection Red vs. Blue: Reconstruction]]'' - when an [=AI=] is implanted in a character, the effect is described as being "of the same mind", where the two entities share thoughts. Though the host is usually able to maintain his or her their identity (even if free will is lost), Agent Maine (better known as [[TheJuggernaut the Meta]]) degenerated into a mindless husk after playing host to 7 different [=AI=]s ''at once'' and stayed that way even when the [=AI=]s were removed. Of particular note is the fact that all 7 [=AI=]s were {{Literal Split Personalit|y}}ies of another [=AI=], the Alpha.
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* A positive example occurs in ''Series/TheTwilightZone1959''. In the episode "[[Recap/TheTwilightZoneS2E39NervousManInAFourDollarRoom Nervous Man in a Four Dollar Room]]", a small-time thug is ordered to kill someone for the first time in his life. His long-buried conscience, manifesting as [[TheManInTheMirrorTalksBack his reflection given a life of its own]], refuses to go along with committing murder and takes over as the dominant personality.

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* A positive example occurs in ''Series/TheTwilightZone1959''. In the episode "[[Recap/TheTwilightZoneS2E39NervousManInAFourDollarRoom "[[Recap/TheTwilightZone1959S2E3NervousManInAFourDollarRoom Nervous Man in a Four Dollar Room]]", a small-time thug is ordered to kill someone for the first time in his life. His long-buried conscience, manifesting as [[TheManInTheMirrorTalksBack his reflection given a life of its own]], refuses to go along with committing murder and takes over as the dominant personality.
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* ''WesternAnimation/TheSimpsons'': The "Treehouse Of Horror XXXIV" segment "[=Ei8ht=]" is set in an AlternateContinuity in which Sideshow Bob successfully murdered Bart in "Cape Feare". While the adult Lisa, now a criminal psychologist, assumed she overcame the trauma of watching Bart die, [[spoiler:she developed a second murderous personality that murdered many firstborn Springfielders. She eventually gets total control after Lisa is arrested, considering the original personality another of her victims.]] To Sideshow Bob however, he complains about how [[ClicheStorm cliche]] the SplitPersonality trope is, which doubles as a [[BreakingTheFourthWall Fourth Wall break]].
-->'''Sideshow Bob:''' Trope alert! Call the first thought police!
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* A positive example occurs in ''Series/TheTwilightZone1959''. In the episode "[[Recap/TheTwilightZoneS2E39NervousManInAFourDollarRoom Nervous Man in a Four Dollar Room]]", a small-time thug is ordered to kill someone for the first time in his life. His long-buried conscience refuses to go along with committing murder and takes over as the dominant personality.

to:

* A positive example occurs in ''Series/TheTwilightZone1959''. In the episode "[[Recap/TheTwilightZoneS2E39NervousManInAFourDollarRoom Nervous Man in a Four Dollar Room]]", a small-time thug is ordered to kill someone for the first time in his life. His long-buried conscience conscience, manifesting as [[TheManInTheMirrorTalksBack his reflection given a life of its own]], refuses to go along with committing murder and takes over as the dominant personality.
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* ''Literature/SkulduggeryPleasant'' has a couple:
** Valkyrie suffers this from [[spoiler: Darquesse]], her SuperpoweredEvilSide, as the latter gets more powerful. Ironically, she'd had her True Name sealed to try and ''prevent'' this or being compelled to become [[spoiler: Darquesse]] after seeing a BadFuture where [[spoiler: Darquesse]] killed her parents along with practically everyone else. Unfortunately, a brief case of possession opened the door for the personality in question to get loose, which she also did when something rummaged around in her head or when Valkyrie was near death (which Valkyrie once exploited to fight [[TheDreaded Lord Vile]]). After that, she started whispering in Valkyrie's head more and more, finally refusing to come out when Valkyrie was ''being literally ripped apart'' and [[MindRape mentally torturing]] her into giving in.
** [[spoiler: Skulduggery]] has to deal with this risk with Lord Vile, a split personality formed out of immense trauma and rage that bound itself to his latent talent for necromancy. While he buried Vile centuries ago and became TheAtoner, further trauma and proximity to the armour means the personality subconscious reanimates the armour (which nearly kills him). He is ultimately forced to become Vile again by putting on the armour as a GodzillaThreshold on more than one occasion, and while he manages to put him back in his box, he makes plain that every time he puts on the armour there is a very real chance that he may not come back and will have to be stopped by force. This isn't exactly easy, either: prior to the rise of Darquesse, Lord Vile was arguably the most feared sorcerer in history, even more so than his former master Mevolent (the Leibniz Universe implies that Vile was actually more powerful, and shows that Mevolent is surprisingly AffablyEvil with plenty of human qualities. Aside from the odd QuizzicalTilt, Vile has none whatsoever), and it takes a [[PhysicalGod True Name sorcerer]] or Mevolent himself to even have a prayer of beating him - and one of the two True Name sorcerers we see is a pacifist who makes sure to hide the armour, admitting that Vile's combination of sheer power, skill, and killer instinct could very possibly kill him, while [[spoiler: Leibniz Vile beats Mevolent when they fight]].
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* ''ComicBook/NewMutants:'' Legion often runs the risk of this. In his first full appearance, the team are dragged inside his mind, where there's a battle going on between two alters (rogue {{Jerkass}} Jack and volatile pyrokinetic Cyndi) and another person who got dragged inside David's mind years ago. It eventually turns out to be an inverted case; the alters are battling against being erased, while the guy is trying to heal David's shattered psyche. The next time David reappears, Jack violently seizes control, tries to murder Moira [=MacTaggert=] and Wolfsbane, and runs off to hit the nearest bar and get some action. Part of the problem the New Mutants have is they want to restore David, but have no idea on how to ''do'' that.
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-> ''"This, then, is the last time, short of a miracle, that Henry Jekyll can think his own thoughts or see his own face (now how sadly altered!) in the glass."''

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-> --> ''"This, then, is the last time, short of a miracle, that Henry Jekyll can think his own thoughts or see his own face (now how sadly altered!) in the glass."''
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* ''Manga/{{Bleach}}'': Hollow transformations consist of the original personality of a Plus being largely destroyed in favour of something created from raw instinct. The effect is permanent; even if a Hollow can resist the effect (such as Sora), it's only a temporary measure at best. The effect ''does'' lessen as a Hollow goes through its stages of evolution and their personality reverts closer to their original as their never-ending hunger becomes sated (Adjuchas and Vasto Lorde level, as well as becoming an Arrancar), but that takes a long time and a ''lot'' of devoured creatures to get to. And when that happens, there's no guarantee that it'll be the original soul that will be in control. It's possible for any of the other souls that a Hollow has devoured to take over from the inside and become the dominant personality, if it's strong-willed enough.

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* ''Manga/{{Bleach}}'': Hollow transformations consist of the original personality of a Plus being largely destroyed in favour of something created from raw instinct. The effect is permanent; even if a Hollow can resist the effect (such as Sora), it's only a temporary measure at best. The effect ''does'' lessen as a Hollow goes through its stages of evolution as a Menos and their personality reverts closer to their original as their never-ending hunger becomes sated (Adjuchas and Vasto Lorde level, as well as becoming an Arrancar), but that takes a long time and a ''lot'' of devoured creatures to get to. And when that happens, there's no guarantee that it'll be the original soul that will be in control. control of the Menos. It's possible for any of the other souls that a Hollow Menos has devoured to take over from the inside and become the dominant personality, if it's strong-willed enough.
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** The reverse of Bruce's fear is actually realized in the next appearance after this, ''Film/AvengersEndgame'' he remains in Hulk form for the entire film, but retains Bruce's mind.

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** The reverse of Bruce's fear is actually realized in the next appearance after this, ''Film/AvengersEndgame'' he remains in Hulk form for the entire film, [[SplitPersonalityMerge but retains Bruce's mind.mind]], a state both are happy with.
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* ''Series/DoctorWho'': In "[[Recap/DoctorWhoS33E12NightmareInSilver Nightmare in Silver]]", the Doctor has to fend off the Cyber-Planner that calls itself [[EvilIsHammy Mr. Clever]] when it attempts to take over his mind. Seeing Creator/MattSmith ActingForTwo in a Sméagol/Gollum type fight is equal parts awesome and hilarious, with a touch of bone-chilling sinister thrown in by the [[Creator/NeilGaiman the episode's author]].

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* ''Series/DoctorWho'': In "[[Recap/DoctorWhoS33E12NightmareInSilver Nightmare in Silver]]", the Doctor has to fend off the Cyber-Planner that calls itself [[EvilIsHammy Mr. Clever]] when it attempts to take over his mind. Seeing Creator/MattSmith ActingForTwo in a Sméagol/Gollum type fight is equal parts awesome and hilarious, with a touch of bone-chilling sinister thrown in by the [[Creator/NeilGaiman the episode's author]].

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Alphabetizing.


* In Creator/FrankMiller's ''ComicBook/BatmanTheDarkKnightReturns'', Harvey Dent has received surgery to repair his face's damaged half, but it has the opposite effect on his mind - ComicBook/TwoFace is now entirely in control.
%%* Michael Moran does this to himself in Creator/AlanMoore's run of ''{{ComicBook/Miracleman}}''.
* There's a ''Franchise/SpiderMan'' arc involving Symbiote knockoffs. ComicBook/{{Venom}}, of course, always refers to himself as 'We' (as in, Eddie Brock and his Symbiote), so when one of the symbiotes stops talking in plural, Spidey knows that she's all gone - the Symbiote has taken over her mind. An interesting conclusion of this is that the very thing that makes Venom sound like a raving lunatic is actually an indication of his remaining sanity - or even a psychic crutch necessary for him to retain his identity.
* While it wasn't made as big a deal of as the animated version, it used to be that the Goblin Serum gave ComicBook/NormanOsborn a SplitPersonality, and would periodically forget he had a SuperpoweredEvilSide and go back to being an industrialist. Since he came BackFromTheDead, it seems to be accepted that he's the Goblin all the time. Though during his time on ''ComicBook/{{Thunderbolts}}'' and ''ComicBook/DarkReign'', it seems the split personality explanation is back. Subverted in that Osborn is still an evil jerk, the Goblin is just his darker side. At the end of "Goblin War", [[spoiler: the Goblin formula is flushed from his system, and he declares that Spider-Man has never faced a Green Goblin who's ''sane'' before..]].
* What caused Brainwave's initial FaceHeelTurn after the end of ''ComicBook/InfinityInc'' About fifteen years later, [[EnemyWithin the new personality]] got possessed by [[PuppeteerParasite a ''third'', also villainous, personality]]. Eventually, when the third personality was defeated, it was heavily implied that the third personality ''ate'' the second one. In any case, [[HeelFaceTurn he got better]].
%%* A horribly tragic case occurred to Dan Turpin during ''ComicBook/FinalCrisis''. To be fair it skirts between this and DemonicPossession, but after visiting Bludhaven in search for missing children, Danny starts getting blackouts and finds he can't control himself after a certain point. He then discovers with horror that he is being '''possessed and/or erased''' by [[GodOfEvil Darkseid]]. After he is completely possessed, he is poisoned by Batman, nearly killed by the Black Racer, and finally and utterly destroyed by Superman.
%%** The final issue implies, but never outright states, that it was only Darkseid who got destroyed and Turpin was ultimately freed. It's probably a moot point now that DC has reset the universe again.

to:

* In Creator/FrankMiller's ''ComicBook/BatmanTheDarkKnightReturns'', Harvey Dent has received surgery to repair [[TwoFaced his face's damaged half, half]], but it has the opposite effect on his mind - ComicBook/TwoFace -- Two-Face is now entirely in control.
%%* Michael Moran does * In ''ComicBook/BuffyTheVampireSlayer'', it's shown that [[OurWerewolvesAreDifferent Oz]] came very close to going down this road ''willingly''. He had been trying to himself in Creator/AlanMoore's run of ''{{ComicBook/Miracleman}}''.
* There's a ''Franchise/SpiderMan'' arc involving Symbiote knockoffs. ComicBook/{{Venom}}, of course, always refers to himself as 'We' (as in, Eddie Brock and his Symbiote), so when one of the symbiotes stops talking in plural, Spidey knows that she's all gone - the Symbiote has taken over her mind. An interesting conclusion of this is that the very thing that makes Venom sound like a raving lunatic is actually an indication of his remaining sanity - or even a psychic crutch necessary for him to retain his identity.
* While it wasn't made as big a
deal of as the animated version, it used to be that the Goblin Serum gave ComicBook/NormanOsborn a SplitPersonality, and would periodically forget he had a SuperpoweredEvilSide and go back to being an industrialist. Since he came BackFromTheDead, it seems to be accepted that he's the Goblin all the time. Though during his time on ''ComicBook/{{Thunderbolts}}'' and ''ComicBook/DarkReign'', it seems the split personality explanation is back. Subverted in that Osborn is still an evil jerk, the Goblin is just his darker side. At the end of "Goblin War", [[spoiler: the Goblin formula is flushed from his system, and he declares that Spider-Man has never faced a Green Goblin who's ''sane'' before..]].
* What caused Brainwave's initial FaceHeelTurn after the end of ''ComicBook/InfinityInc'' About fifteen years later,
with [[EnemyWithin the new personality]] got possessed by [[PuppeteerParasite his werewolf side]] for a ''third'', also villainous, personality]]. relatively long time, only to learn that whatever he tried was pointless and whatever ground he had gained before was lost. Eventually, when the third giving in and simply being ''done'' with it all started to look very tempting. It's never explicitly stated why he didn't go through with it, but [[TheStoic his words]] "But I didn't" are [[YouAreNotAlone coupled with an image of Bayarmaa]], [[spoiler:his future wife and mother of his son]].
* ''ComicBook/{{Daredevil}}'': This is Bloody Mary/Typhoid Mary's entire schtick. She has rather impressive psychic and telekinetic powers, but she also has a horrible case of disassociative identity disorder; namely, at least nine of them. Two of them (the aforementioned Bloody/Typhoid Marys) tend to take over more often than not, and there have been at least two instances where one or both have "permanently" taken over only for later events to unlock her original (non-powered)
personality was defeated, it was heavily implied that once more.
%%* ''ComicBook/{{Etrigan}}'': This has happened to Jason Blood from time to time, depending on who's writing
the third personality ''ate'' the second one. In any case, [[HeelFaceTurn he got better]].
%%*
Demon.
*
A horribly tragic case occurred occurs to Dan Turpin during ''ComicBook/FinalCrisis''. To be fair fair, it skirts between this and DemonicPossession, but after visiting Bludhaven in search for missing children, Danny starts getting blackouts and finds that he can't control himself after a certain point. He then discovers with horror that he is being '''possessed ''possessed and/or erased''' erased'' by [[GodOfEvil Darkseid]]. After he is completely possessed, he is poisoned by Batman, nearly killed by the Black Racer, and finally and utterly destroyed by Superman.
%%**
Superman. The final issue implies, but never outright states, that it was it's only Darkseid who got is destroyed and that Turpin was is ultimately freed. It's probably a moot point now that DC has reset the universe again.



** Betty Ross was in constant risk of this when she was Red She-Hulk.
** The reason Doc Samson turned evil in ''ComicBook/Hulk2008''; he developed another set of personalities- his current persona, the identity of Doctor Leonard Samson [=PhD=], and the more ruthless 'Samson'- and a 'psychiatric evaluation' in his own mind organised by M.O.D.O.K. saw Samson kill the other two.

to:

** Betty Ross was is in constant risk of this when she was becomes Red She-Hulk.
** The This is the reason why Doc Samson turned turns evil in ''ComicBook/Hulk2008''; he ''ComicBook/Hulk2008''. He developed another set of personalities- personalities -- his current persona, the identity of Doctor Leonard Samson [=PhD=], and the more ruthless 'Samson'- 'Samson' -- and a 'psychiatric evaluation' in his own mind organised organized by M.O.D.O.K. saw Samson kill the other two.



** Has happened to the evil future version of the Hulk called the Maestro. There's no more Banner, no more Hulk, or Joe, or any of the others. It's just the Maestro now.
* During the ''ComicBook/SpiderMan'' storyline ''The Gauntlet'', [[spoiler: Curt Connors']] worst fears are realized when [[spoiler: he loses a battle of wills with the Lizard part of his psyche]]. [[spoiler: The Lizard kills and ''eats'' Curt's ''son'' Billy, and "Curt" essentially dies due to the trauma, leaving only The Lizard]]. A later story reverses this: [[spoiler: Spider-Man manages to bring Curt's body back, but doesn't realise it's still the Lizard's mind. Then the Lizard reverts to his usual form, but ''this'' restores Curt's mind. Curt keeps this quiet because he feels he ''deserves'' to be locked up]].
* This was Bloody Mary[=/=]Typhoid Mary's (a villainess most often found in ''ComicBook/{{Daredevil}}'') entire schtick. She had rather impressive psychic and telekinetic powers, but she also had a horrible case of multiple personality disorder; namely, at least nine of them. Two of them (the aforementioned Bloody/Typhoid Marys) tended to take over more often than not, and there have been at least two instances where one or both have "permanently" taken over only for later events to unlock her original (non-powered) personality once more.
* Happened to [[ComicBook/UltimateMarvel Ultimate]] Comicbook/MoonKnight. Doubles as a case of BecomingTheMask, since the personality that took over was created specifically to be more evil and violent.
%%* ''ComicBook/{{Etrigan}}'': This has happened to Jason Blood from time to time, depending on who's writing the Demon.
* In [[UsefulNotes/TheSilverAgeOfComicBooks Silver Age]] Creator/DCComics, Priscilla Rich's jealousy and envy of Franchise/WonderWoman caused her to spawn a second personality. As the ComicBook/{{Cheetah}}, she became a recurrent foe in the ''ComicBook/SensationComics'' and ''ComicBook/{{Wonder Woman|1942}}'' series.
* This happened to ComicBook/ProfessorX in ''ComicBook/{{Onslaught}}'' as the title villain is Xavier's dark side merged with the basest parts of ComicBook/{{Magneto}}'s and run amok.

to:

** Has This has happened to the evil future version of the Hulk called the Maestro.Maestro from ''ComicBook/TheIncredibleHulkFutureImperfect''. There's no more Banner, no more Hulk, or Joe, or any of the others. It's just the Maestro now.
* This is what causes Brainwave's initial FaceHeelTurn after the end of ''ComicBook/InfinityInc''. About fifteen years later, [[EnemyWithin the new personality]] is possessed by [[PuppeteerParasite a ''third'', also villainous, personality]]. Eventually, when the third personality is defeated, it's heavily implied that it ''ate'' the second one. In any case, [[HeelFaceTurn he gets better]].
%%* Michael Moran does this to himself in Creator/AlanMoore's run of ''ComicBook/{{Miracleman}}''.
* This happens to Professor X in ''ComicBook/{{Onslaught}}'' as the title villain is Xavier's dark side merged with the basest parts of Magneto's and run amok.
* ''ComicBook/SpiderMan'':
** While it wasn't made as big a deal of as the animated version, it used to be that the Goblin Serum gave Norman Osborn a SplitPersonality, and would periodically forget that he had a SuperpoweredEvilSide and go back to being an industrialist. Since he came BackFromTheDead, it seems to be accepted that he's the Goblin all the time. Though during his time on ''ComicBook/{{Thunderbolts}}'' and ''ComicBook/DarkReign'', it seems the split personality explanation is back. Subverted in that Osborn is still an evil jerk, the Goblin is just his darker side. At the end of "Goblin War", [[spoiler:the Goblin formula is flushed from his system, and he declares that Spider-Man has never faced a Green Goblin who's ''sane'' before]]...
** One story arc involves Symbiote knockoffs. ComicBook/{{Venom}}, of course, always refers to himself as 'We' (as in, Eddie Brock and his Symbiote), so when one of the symbiotes stops talking in plural, Spidey knows that she's all gone -- the Symbiote has taken over her mind. An interesting conclusion of this is that the very thing that makes Venom sound like a raving lunatic is actually an indication of his remaining sanity -- or even a psychic crutch necessary for him to retain his identity.
**
During the ''ComicBook/SpiderMan'' storyline ''The Gauntlet'', [[spoiler: Curt [[spoiler:Curt Connors']] worst fears are realized when [[spoiler: he [[spoiler:he loses a battle of wills with the Lizard part of his psyche]]. [[spoiler: psyche. The Lizard kills and ''eats'' Curt's ''son'' Billy, and "Curt" essentially dies due to the trauma, leaving only The the Lizard]]. A later story reverses this: [[spoiler: Spider-Man [[spoiler:Spider-Man manages to bring Curt's body back, back but doesn't realise realize that it's still the Lizard's mind. Then the Lizard reverts to his usual form, but ''this'' restores Curt's mind. Curt keeps this quiet because he feels he ''deserves'' to be locked up]].
up.]]
* This was Bloody Mary[=/=]Typhoid Mary's (a villainess most often found happens to Moon Knight in ''ComicBook/{{Daredevil}}'') entire schtick. She had rather impressive psychic and telekinetic powers, but she also had a horrible case of multiple personality disorder; namely, at least nine of them. Two of them (the aforementioned Bloody/Typhoid Marys) tended to take over more often than not, and there have been at least two instances where one or both have "permanently" taken over only for later events to unlock her original (non-powered) personality once more.
* Happened to [[ComicBook/UltimateMarvel Ultimate]] Comicbook/MoonKnight.
''ComicBook/UltimateSpiderMan''. Doubles as a case of BecomingTheMask, since the personality that took takes over was created specifically to be more evil and violent.
%%* ''ComicBook/{{Etrigan}}'': This has happened to Jason Blood from time to time, depending on who's writing the Demon.
* ''ComicBook/WonderWoman'': In [[UsefulNotes/TheSilverAgeOfComicBooks Silver Age]] Creator/DCComics, Priscilla Rich's jealousy and envy of Franchise/WonderWoman Wonder Woman caused her to spawn a second personality. As the ComicBook/{{Cheetah}}, Cheetah, she became a recurrent foe in the ''ComicBook/SensationComics'' and ''ComicBook/{{Wonder Woman|1942}}'' series.
* This happened to ComicBook/ProfessorX in ''ComicBook/{{Onslaught}}'' as the title villain is Xavier's dark side merged with the basest parts of ComicBook/{{Magneto}}'s and run amok.
''ComicBook/WonderWoman1942'' series.






* Basically what happened to Talia in ''Series/BabylonFive''. There was also a rogue telepath in one episode that goes through this.
* ''Franchise/{{Buffyverse}}'':
** In season 8, it's shown [[OurWerewolvesAreDifferent Oz]] came very close to going down this road ''willingly''. He had been trying to deal with [[EnemyWithin his werewolf side]] for a relatively long time, only to learn that whatever he tried was pointless and whatever ground he had gained before was lost. Eventually giving in and simply being ''done'' with it all started to look very tempting. It's never explicitly stated why he didn't go through with it, but [[TheStoic his words]] "But I didn't" are [[YouAreNotAlone coupled with an image of Bayarmaa]], [[spoiler: his future wife and mother of his son]].
** This happens to Angel whenever Angelus is unleashed.
* In an episode of ''Series/CriminalMinds'', a young man's murderous and until-then unknown alter ego permanently takes over his body, in an attempt to protect him. In a twist, the alter ego that took over was ''female''.
-->'''Dr. Reid:''' I am looking for Adam.
-->'''Amanda:''' Just because you caught me doesn't mean you'll find him. You're not that smart.

to:

* Basically ''Series/BabylonFive'': This is basically what happened happens to Talia [[ManchurianAgent Talia]] in ''Series/BabylonFive''. "[[Recap/BabylonFiveS02E19DividedLoyalties Divided Loyalties]]". There was is also a rogue telepath in one episode that who goes through this.
* ''Franchise/{{Buffyverse}}'':
** In season 8, it's shown [[OurWerewolvesAreDifferent Oz]] came very close to going down this road ''willingly''. He had been trying to deal with [[EnemyWithin his werewolf side]] for a relatively long time, only to learn that whatever he tried was pointless and whatever ground he had gained before was lost. Eventually giving in and simply being ''done'' with it all started to look very tempting. It's never explicitly stated why he didn't go through with it, but [[TheStoic his words]] "But I didn't" are [[YouAreNotAlone coupled with an image of Bayarmaa]], [[spoiler: his future wife and mother of his son]].
**
''Franchise/{{Buffyverse}}'': This happens to Angel whenever Angelus is unleashed.
* In an episode of ''Series/CriminalMinds'', a young man's murderous and until-then unknown alter ego permanently takes over his body, in an attempt to protect him. In a twist, the alter ego that took takes over was ''female''.
is ''[[MultiGenderedSplitPersonalities female]]''.
-->'''Dr. Reid:''' I am looking for Adam.
-->'''Amanda:'''
Adam.\\
'''Amanda:'''
Just because you caught me doesn't mean you'll find him. You're not that smart.



* ''Series/DoctorWho'': The Eleventh Doctor has to fend off the Cyber Planner that calls itself [[EvilIsHammy Mr. Clever]] when it attempts to take over his mind. Seeing Creator/MattSmith ActingForTwo in a Sméagol/Gollum type fight is equal parts awesome and hilarious, with a touch of bone-chilling sinister thrown in by the [[Creator/NeilGaiman the episode's author.]]
* Played with in ''Series/{{Farscape}}''. Thanks to Scorpius' [[MoralityChip neuro chip]], Scorpius' "neural clone" gets stronger and stronger within Crichton over the course of the second season... until taking over completely in the finale. Even after surgery removes the chip itself, the neural clone, "[[NotSoImaginaryFriend Harvey]]", never really disappears.
** Once the chip is removed though Harvey loses any power he had and is basically trapped in John's head forever, with John able to shut him up whenever he wishes. The best Harvey can do to John is be mildly irritating - unless his life is in danger, in which case, Harvey can muster up ''just'' enough power to be dangerous. In the Peacekeeper Wars mini-series Harvey finally dies for good when the wormhole knowledge is deleted from John's brain.
* In ''Series/TheFlash2014'', this happens to [[spoiler: Caitlin Snow]], who gets taken over by her [[spoiler: Killer Frost]] personality if she uses her powers.
* This happened repeatedly to Nikki on ''{{Series/Heroes}}'' when her SuperpoweredEvilSide decided to start acting up.
* In the "One Last Prayer" episode of Creator/{{HBO}}'s 80s anthology ''The Hitchhiker'', a pretty and talented singer called Miranda invents an image for herself guaranteed to succeed, but finds it starting to take over. [[spoiler: She fights back, but [[TheBadGuyWins The Bad Girl Wins]].]]
* ''{{Series/Jekyll}}'': When [[EvilInc Klein & Utterson]] finally manage to capture Dr. Jackman, they put him into a device that deletes one of the two personalities. Unfortunately for Jackman's wife, Hyde is the surviving personality. [[spoiler: However, when Mrs Jackman and her children are captured due to Hyde's immaturity, he resurrects his dead alter-ego and [[SplitPersonalityMerge merges]] with him, mixing Hyde's incredible strength with Jackman's maturity.]]

to:

* ''Series/DoctorWho'': The Eleventh In "[[Recap/DoctorWhoS33E12NightmareInSilver Nightmare in Silver]]", the Doctor has to fend off the Cyber Planner Cyber-Planner that calls itself [[EvilIsHammy Mr. Clever]] when it attempts to take over his mind. Seeing Creator/MattSmith ActingForTwo in a Sméagol/Gollum type fight is equal parts awesome and hilarious, with a touch of bone-chilling sinister thrown in by the [[Creator/NeilGaiman the episode's author.]]
author]].
* Played with in ''Series/{{Farscape}}''. Thanks to Scorpius' [[MoralityChip neuro chip]], neurochip]], Scorpius' "neural clone" gets stronger and stronger within Crichton over the course of the second season... until taking over completely in the finale. Even after surgery removes the chip itself, the neural clone, "[[NotSoImaginaryFriend Harvey]]", never really disappears.
**
disappears. Once the chip is removed though removed, though, Harvey loses any power he had and is basically trapped in John's head forever, with John able to shut him up whenever he wishes. The best Harvey can do to John is be mildly irritating - -- unless his life is in danger, in which case, case Harvey can muster up ''just'' enough power to be dangerous. In the Peacekeeper Wars mini-series "Peacekeeper Wars" miniseries, Harvey finally dies for good when the wormhole knowledge is deleted from John's brain.
* In ''Series/TheFlash2014'', this happens to [[spoiler: Caitlin [[spoiler:Caitlin Snow]], who gets taken over by her [[spoiler: Killer [[spoiler:Killer Frost]] personality if she uses her powers.
* This happened happens repeatedly to Nikki on ''{{Series/Heroes}}'' in ''Series/{{Heroes}}'' when her SuperpoweredEvilSide decided decides to start acting up.
* In the "One Last Prayer" episode of Creator/{{HBO}}'s 80s 1980s anthology ''The Hitchhiker'', a pretty and talented singer called Miranda invents an image for herself guaranteed to succeed, but finds it starting to take over. [[spoiler: She fights back, but [[TheBadGuyWins The Bad Girl Wins]].]]
* ''{{Series/Jekyll}}'': ''Series/{{Jekyll}}'': When [[EvilInc Klein & Utterson]] finally manage to capture Dr. Jackman, they put him into a device that deletes one of the two personalities. Unfortunately for Jackman's wife, Hyde is the surviving personality. [[spoiler: However, [[spoiler:However, when Mrs Mrs. Jackman and her children are captured due to Hyde's immaturity, he resurrects his dead alter-ego and [[SplitPersonalityMerge merges]] with him, mixing Hyde's incredible strength with Jackman's maturity.]]



** An episode of ''Series/StargateSG1'' had Daniel controlled by several different personalities that got in his head.

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** An episode of ''Series/StargateSG1'' had has Daniel controlled by several different personalities that got get in his head.



* In one episode of ''Series/TalesFromTheCrypt'' a lonely man's only companion is his own split personality. When the man starts dating a therapist, said split personality is afraid that she will destroy him and tries to goad the man into killing her. When the guy refuses, his other half decides to "kill" him and take over his life. In the end, the more assertive personality has cowed his former boss and is on the fast track to becoming an executive and is married to the therapist.

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* In one episode of the ''Series/TalesFromTheCrypt'' episode "[[Recap/TalesFromTheCryptS6E4OperationFriendship Operation Friendship]]", a lonely man's only companion is his own split personality. When the man starts dating a therapist, said split personality is afraid that she will destroy him and tries to goad the man into killing her. When the guy refuses, his other half decides to "kill" him and take over his life. In the end, the more assertive personality has cowed his former boss and is on the fast track to becoming an executive and is married to the therapist.



* A positive example occurs on ''Series/TheTwilightZone1959''. In the episode "Nervous Man In A Four Dollar Room", a small-time thug (Joe Mantell) is ordered to kill someone for the first time in his life. His long buried conscience refuses to go along with committing murder and takes over as the dominant personality.

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* A positive example occurs on in ''Series/TheTwilightZone1959''. In the episode "Nervous "[[Recap/TheTwilightZoneS2E39NervousManInAFourDollarRoom Nervous Man In A in a Four Dollar Room", Room]]", a small-time thug (Joe Mantell) is ordered to kill someone for the first time in his life. His long buried long-buried conscience refuses to go along with committing murder and takes over as the dominant personality.
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* ''Film/CleoLeo'': [[spoiler: Initially 'Cleo' has an internal monologue in Leo's masculine voice indicating that the reincarnation is purely physical. As the film progresses and 'Cleo' adapts to life as a woman the 'Leo' mental voice begins to become fainter and interspersed with an internal voice in Cleo's feminine voice with 'Leo' expressing resentment, anger and reluctance to change while 'Cleo' expresses confusion but also acceptance and femininity including attraction to Bob. Eventually, half way through the movie the 'Leo' voice fades away completely leaving just 'Cleo' as ''she'' begins to think of herself as a woman.]]
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* In ''Literature/{{Dune}}'', the "preborn" (children exposed to the spice ''melange'' in the womb) are at high risk of having their minds swamped and erased by the ancestral personae and memories they are born with. And, in fact, this happens more than once:
** Alia Atreides ends up taken over by the mind of [[spoiler:her late grandfather]] Baron Harkonnen.
** In order to be sure of ruling competently and setting mankind onto the Golden Path, Paul's son Leto II consciously gives up his own mind, allowing his tyrannical but wily ancestor Harum to administer a virtual "council" of personalities in his head.
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* The third season of ''Series/StarTrekPicard'' introduces a new Soong-type android/golem whose mind contains the personalities of both Data and [[EvilTwin Lore]]. Its creator had hoped to merge the personalities but could not get them to harmonize and so he created a partition between the two minds. Desperate circumstances force the crew to remove the partition in the hopes that Data will emerge with complete control. Unfortunately, Data knows that he has no chance to overpower his brother and Lore ultimately takes over -- but because he seized Data's memories, he effectively ''becomes'' Data. Slightly spills into SplitPersonalityMerge as some aspects of Lore's personality (though not the evil ones) are assimilated into the re-emerged Data.
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* ''Film/{{Asylum}}'': In "Lucy Comes to Stay", Barbara has just been released from hospital and brought home by her brother George. She encounters her 'friend' Lucy, who appears (to the audience) to be an ImaginaryFriend. However, as Lucy commits a series of acts, culminating in the murder of George and Nurse Higgins, it seems that she might be a NotSoImaginaryFriend. But when Dr. Martin interviews her in the asylum and asks where Lucy is, Barbara points at the mirror, and when she looks into it, she sees Lucy's reflection looking back at her.

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* ''Film/{{Asylum}}'': ''Film/Asylum1972Horror'': In "Lucy Comes to Stay", Barbara has just been released from hospital and brought home by her brother George. She encounters her 'friend' Lucy, who appears (to the audience) to be an ImaginaryFriend. However, as Lucy commits a series of acts, culminating in the murder of George and Nurse Higgins, it seems that she might be a NotSoImaginaryFriend. But when Dr. Martin interviews her in the asylum and asks where Lucy is, Barbara points at the mirror, and when she looks into it, she sees Lucy's reflection looking back at her.
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* In ''Anime/DigimonGhostGame'', it's revealed that [[spoiler:[[SuperPoweredEvilSide the sadistic and merciless [=GulusGammamon=]]] was the original personality, and kind and childlike Gammamon that is seen throughout the series was a split personality that manifested and took over under unknown circumstances. [=GulusGammamon=] also attempts to pull this off in Episodes 66 and 67 to reclaim control of his own body, but due to the interference of Hiro, he fails and is absorbed into Gammamon fully.]]

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* In ''Anime/DigimonGhostGame'', it's revealed that [[spoiler:[[SuperPoweredEvilSide the sadistic and merciless [=GulusGammamon=]]] was the original personality, and kind and childlike Gammamon that is seen throughout the series was a split personality that manifested and took over under unknown circumstances. [=GulusGammamon=] also attempts to pull this off in Episodes 66 and 67 to reclaim control of his own body, control, but due to the interference of Hiro, he fails and is absorbed into Gammamon fully.]]
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* In ''Anime/DigimonGhostGame'', it's revealed that [[spoiler:[[SuperPoweredEvilSide the sadistic and merciless [=GulusGammamon=]]] was the original personality, and kind and childlike Gammamon that is seen throughout the series was a split personality that manifested and took over under unknown circumstances. [=GulusGammamon=] also attempts to pull this off in Episodes 66 and 67 to reclaim control of his own body, but due to the interference of Hiro, he fails and is absorbed into Gammamon fully.]]
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After months or years of suffering a SplitPersonality, EnemyWithin, or SuperPoweredEvilSide, the character is cured! ...by having the weaker, "sane" personality lose all control over the body to their inner evil. Like the slow erosion of a mountain, [[JekyllAndHyde Jekyll]] has succumbed to [[JekyllAndHyde Hyde]]'s [[ImplacableMan implacable]] [[PassionIsEvil id-like force]], leaving nothing but the shell of who they were.

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After months or years of suffering a SplitPersonality, EnemyWithin, or SuperPoweredEvilSide, [[ExactWords the character is cured! ...cured!]] [[GoneHorriblyRight ...by having the weaker, "sane" personality personality]] lose all control over the body to their inner evil. Like the slow erosion of a mountain, [[JekyllAndHyde Jekyll]] has succumbed to [[JekyllAndHyde Hyde]]'s [[ImplacableMan implacable]] [[PassionIsEvil id-like force]], leaving nothing but the shell of who they were.
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* This happens to the protagonist of Music/NineInchNails's Music/TheDownwardSpiral over the course of the album.

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* This happens to the protagonist of Music/NineInchNails's Music/TheDownwardSpiral ''Music/TheDownwardSpiral'' between the songs "The Becoming" and "I Do Not Want This", during which "the Machine" takes over the course of the album.his mind, culminating in him going on a rampage in "Big Man with a Gun".
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* A positive example occurs with Veyle in ''VideoGame/FireEmblemEngage''. Veyle has two personalities: Her normal personality is a kind and friendly person, but she has an evil personality [[spoiler:caused by Sombron's mind control channeled through a crown]], which enjoys killing and despises humanity, [[spoiler:Acting as TheDragon to Sombron. Eventually Veyle, spurred on by the words of her sibling Alear, rips the crown off, shattering it and leaving the evil personality unable to manifest any more, which the evil Veyle themselves [[DeathOfPersonality considers equivalent to death.]]]]

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* A positive example occurs with Veyle in ''VideoGame/FireEmblemEngage''. Veyle has two personalities: Her normal personality is a kind and friendly person, but she has an evil personality [[spoiler:caused by Sombron's mind control channeled through a crown]], which enjoys killing and despises humanity, [[spoiler:Acting [[spoiler:acting as TheDragon to Sombron. Eventually Veyle, spurred on by the words of her sibling Alear, rips the mind control crown off, shattering it and leaving the evil personality unable to manifest any more, which the evil Veyle themselves [[DeathOfPersonality considers equivalent to death.]]]]
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* A positive example occurs with Veyle in ''VideoGame/FireEmblemEngage''. Veyle has two personalities: Her normal personality is a kind and friendly person, but she has an evil personality [[spoiler:caused by Sombron's mind control channeled through a crown]], which enjoys killing and despises humanity, [[spoiler:Acting as TheDragon to Sombron. Eventually Veyle, spurred on by the words of her sibling Alear, rips the crown off, shattering it and leaving the evil personality unable to manifest any more, which the evil Veyle themselves [[DeathOfPersonality considers equivalent to death.]]]]
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* Near the end of ''VideoGame/PlanescapeTorment'' you get trapped in a place where you encounter three of your previous "incarnations". One wants to take you over so and another simply wants to destroy you. If you manage to forcibly take over the other two or get them to merge with you, you will gain their memories (and a ton of XP). If you fail, you have to destroy them and their memories are lost forever. The third takes no convincing to get him to merge with you and is more than happy to.

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* Near the end of ''VideoGame/PlanescapeTorment'' you get trapped in a place where you encounter three of your previous "incarnations". One The Practical Incarnation wants to take do this to you over so because he can't accept that he lost and another simply got killed despite his ruthlessness. You can't convince him out on it, but you can turn his attempt back on him to absorb him. The Paranoid Incarnation thinks you're a bodysnatcher/impostor and wants to destroy you. He'll submit to a SplitPersonalityMerge if you can convince him otherwise. If you can't manage to forcibly take over the other two or get them to merge with you, you will gain their memories (and a ton of XP). If you fail, you that, you'll have to destroy kill them and their memories are lost forever. lose the [=XP=] you could get from merging with them. The third takes final you, the Good Incarnation, has no convincing desire to get him to merge do anything like this and willingly merges with you and is more than happy to.without making you fight for it.

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