History Main / OneCurseLimit

** This [[GoodBadBugs can be exploited]] in ''VideoGame/TrialsOfMana'' to heal all status ailments on the party for free. Using the Minor Mallet will make your team miniature, replacing whatever status effect they have, and using it again will invert the miniature status effect turning them to normal.[[note]]This only works in the SNES version, both the original and in ''Collection of Mana''; the 2020 remake makes it into a key item and forbids its use outside the Koropokkur village.[[/note]] It's also [[SlidingScaleOfGameplayAndStoryIntegration integrated in the story]] in that there is an NPC who wears a cursed choker that can... choke her to death, but on the plus side, this makes her immune to MindControl.

* In the second season of the [[WebVideo/ImAMarvelAndImADC Randomverse]], Joker's attempt to turn all the heroes into brainwashed DarkerAndEdgier versions of themselves doesn't work on Franchise/SpiderMan because Mephisto has already altered his mind.

* In ''Franchise/{{Pokemon}}'', any given Pokémon can only be under one of the major status effects (Sleep, Paralysis, Burn, Freeze, Poison) at a time. They can still be affected by secondary status effects like Confusion or Attraction, but a burnt Pokémon can't be paralyzed, and a poisoned Pokémon can't be frozen. In fact, in competitive echelons, players often ''intentionally'' inflict their own Pokémon with a status that isn't much of a bother, purely to prevent more crippling ones: for instance, a Pokémon with the "Guts" ability may be given a Flame Orb (which burns the holder) to trigger the ability[[note]]Guts increases the Pokémon's attack power and ignores the Burn status's attack drop[[/note]] while also rendering them immune to Paralysis or Sleep.

* In ''Anime/DragonPink'' a magic sword obtained after defeating a monster had a death curse on it: Santa immediately falls sick and his lifeforce is slowly being drained away, but Pink (who's already cursed) is not affected.

* PlayedWith in ''Manga/BloodBlockadeBattlefront''. "[[IronicNickname Lucky]]" Blitz T. Abrams has been inflicted with so many curses that they canceled each other out--for him, at least. Everyone around him, however, suffers from egregious amounts of bad luck.
* In the ''Manga/DeathNote'' universe, once your name is written in a Death Note, you can't be affected by any other Death Note. Of course, since you're going to die within the next 23 days ''at most'', it's a rather cold comfort (but see the movie, below).

* In ''Manga/OnePiece'' eating a second [[CursedWithAwesome Devil's Fruit]] is supposedly fatal. [[spoiler: Stealing powers]] however is perfectly okay. Though there seems to be something unique about the character who is able to do that which allows it.

* ''TabletopGame/ArkhamHorror'': The StatusEffects "Blessed" and "Cursed" cancel each other out and can't stack with themselves, so if a Cursed character would get another Curse, they ignore it. All Curses are the same -- only rolls of 6 in the pool of six-sided dice count as successes, compared to 5-6 by default and 4-6 for a Blessed character.

--> -- ''VideoGame/WorldOfWarcraft''

* In ''TabletopGame/NewWorldOfDarkness'', no creature in existence may have more than one supernatural template. Vampires cannot Embrace werewolves, mages cannot undergo the First Change, supernatural creatures stolen away to Arcadia cannot become changelings, and using a supernatural being's body to make a Promethean only makes a new Promethean, with all previous powers and abilities lost. The only partial exception is that the ghosts of mages can still use the magic they knew in life... and even ''that'' is altered into a form befitting their new state.

* Averted in ''VideoGame/TheJackboxPartyPack'' game Monster Seeking Monster, anyone is capable of being turned into a werewolf, a zombie, a vampire, or obtaining the mummy's curse simultaneously.