History Main / IdealIllnessImmunity

* In ''WesternAnimation/TheSimpsons'', Mr. Burns has every known disease and a few new ones.

Compare STDImmunity and WeWillHavePerfectHealthInTheFuture. May coexist with NighInvulnerable--in this trope's case, it's the immune system that is invulnerable to viruses and bacterial strains.

* Poison Ivy from ''ComicBook/{{Batman}}'' is said to be immune to all toxins and diseases. This becomes a plot point in ''Batman: Contagion'', in which Batman asks her help to deliver an experimental cure for the [[ThePlague Ebola Gulf-A]] into a quarantined area.
* The ComicBook/LegionOfSuperHeroes once fight a villain named Immune whose sole superpower is resistance to all forms of disease.
* In ''ComicBook/TeenTitans'', one of the side effects of Beast Boy's powers is that he's incapable of getting sick. This apparently didn't carry over to [[WesternAnimation/TeenTitans2003 the cartoon]], since one episode had him getting a cold.
* ComicBook/TheIncredibleHulk is immune to pretty much every disease on Earth, including AIDS. This becomes a plot point when his old friend Jim Wilson returns to his life having contracted AIDS, and has to deal with the dilemma whether to [[SuperhumanTransfusion give Jim a transfusion of his blood]] which could save his life, but condemn him to a life much like his. [[ReedRichardsIsUseless He doesn't go through with it]].

* ''ComicBook/{{PS238}}'': [[FlyingBrick F.I.S.S. metahumans]] have superpowered immune systems alongside everything else and are immune to most common forms of sickness. [[spoiler:Even an alien bio-weapon is defeatable in its early stages by a F.I.S.S. blood donation, although a PowerNullifier is needed to keep the blood from killing the patient afterwards.]] Guardian Angel is also immune to disease, but that's because her GuardianEntity prevents all harm from coming to her -- [[spoiler:when the same PowerNullifier is used on her, it turns out that she has no 'natural' immune system from birth at all and she is killed by a ''Rhinovirus'' infection]].
* In the Franchise/MarvelUniverse, whether it's being an [[ComicBook/TheEternals Eternal]], a god, or a Herald of [[Characters/MarvelComicsGalactus Galactus]], if a character has immortality then a total immunity to disease is also part of the package.

* Brandon Breyer from ''Film/BrightBurn'' has never been sick, owing to his extraterrestrial nature.
* Likewise Damian Thorn from the ''Film/TheOmen'' never gets ill with any common childhood illnesses, and is apparently also immune to dangerous chemicals.

* The elves in ''Franchise/TolkiensLegendarium'' are [[OurElvesAreDifferent utterly unaffected by diseases, along with other nifty talents]].
* The eponymous witchers of the ''Franchise/TheWitcher'' saga, including the protagonist Geralt, are immune to all known diseases (including plague, which is new to his world) as a result of their mutation. Which, incidentally, allows them to [[STDImmunity screw around without fear of STDs]].
* Most humans born on Earth in the ''Literature/NoonUniverse'' undergo the procedure called "fukamization", which renders them impervious to all diseases and even harmful radiation.
* In the ''Literature/{{Newsflesh}}'' series, a genetically modified virus means people are immune to the common cold and [[CureForCancer never get cancer]]. Instead they turn into zombies.

* This is one of the superhuman, vaguely-[[OurElvesAreDifferent elven]] characteristics popularly attributed to [[RoyalBlood the Targaryens]] in ''Literature/ASongOfIceAndFire'', with Daenerys being confident enough of this that she personally tends to people dying of the flux ([[CallARabbitASmeerp i.e. dysentery]]). As to the accuracy of this belief, there are multiple historical cases related in the books of Targaryens getting ill (Princesses Maegelle and Daenerys -- daughters of Jaehaerys I -- died of grayscale and what sounds like a flu, Aegon III of consumption, Viserys II of a unknown illness[[note]]which admittedly may have been poison[[/note]], Daeron II and his two immediate heirs of the Great Spring Sickness, Jaehaerys II -- Daenerys' own grandfather -- of another unknown illness, and Maester Aemon of pneumonia), [[spoiler:and Dany is displaying mysterious symptoms of ''something'' at the end of ''A Dance with Dragons'']].
* In ''Literature/{{Renegades}}'', an artifact called the Amulet of Vitality grants the wearer the immunity not only to all diseases, but also poisons and superpowers that mess with the body, such as PowerParasite. After Adrian tatooes its pattern on himself with his PowerOfCreation, he's similarly immune.

* ''Literature/CityOfBones1995'': Krismen are bio-engineered to be highly resistant to the venom of various desert creatures, as well as immune to heatstroke and most diseases that afflict humans—and also can't be affected by [[spoiler:Wardens' soul reading or the Inhabitants' MindRape]]. However, they can contract infection from bad wounds or from forcing foreign objects into their pouch.

* ''Series/TheOuterLimits1995'': The episode "[[Recap/TheOuterLimits1995S1E15TheNewBreed The New Breed]]" involves prototype [[{{Nanomachines}} nanites]] developed to make this a reality. Basically, the nanites are designed to move through the body and look for any cellular abnormalities. The damaged or mutated cells would then be restored to their original state. And yes, someone even accuses the scientist who develops them of playing God. Unfortunately, a friend of his decides to inject himself with the nanites before they're fully tested. Given the nature of the series, things [[GoneHorriblyWrong go horribly wrong]].
* The Ferengi in ''Franchise/StarTrek'' are immune to almost all known diseases, but they can get infections.

* A variation with the [[HumanAliens Irathient]] in ''Series/{{Defiance}}''. They are immune to most diseases, but they can still be carriers. This is one of the reasons they are looked down upon by most races, especially since they are inherently distrustful of vaccines.
* Played with in ''Series/TheOfficeUS''. Dwight claims that he has never been sick in his life. Jim rightly points out that Dwight shouldn't have any immunities then.
* This is the plot of ''Series/TheImmortal1969''. The protagonist is immune to all known diseases, and a lot of people want to chase him down and get his blood because of it.

* In ''TabletopGame/DungeonsAndDragons'':

* One option for the "Life Support" power in ''TabletopGame/{{Champions}}'' is Immunity to All Terrestrial Diseases, 5 points. Or you can just buy Immunity to a specific disease, but if you want multiple immunities, it's cheaper to just buy the whole thing.

** The SpaceMarines of are all immune to illness by designs of their maker, the [[GodEmperor Emperor of Mankind]].

* ''TabletopGame/DarkHeresy'' and the other ''[=WH40K=]'' [=RPGs=] have a few traits that make a being immune to diseases (among other things), most notably "machine" (commonly found on machines, but also on techpriests and other heavily cyberneticized beings) and "stuff of nightmares" (usually associated with things like Daemons; gives the being, as stated by the rulebook, "an appalling list of immunities"). Dark Eldar Haemonculi and their fleshcrafted minions also have a trait that makes the immune to poisons and diseases.
* ''TabletopGame/{{GURPS}}'' 3E has the Advantage called Immunity to Disease, which gives complete immunity to all diseases. The Advantage called Immortality includes Immunity to Disease.
** The fourth edition has the Immunity to Disease advantage (along with lesser versions which give bonuses to resisting diseases). It does not come standard with any level of Unkillable (4e's version of the Immortality advantage).
* In ''TabletopGame/SeventhSea'', characters with Sidhe Blood can take a blessing which makes them age more slowly and makes them immune to illness.
* The ''TabletopGame/{{Exalted}}'' are highly resistant to disease, but not completely immune. Some magic, however, can grant such immunity, like the appropriately named Solar charm [[ExactlyWhatItSaysOnTheTin Immunity to Everything Technique]].
* In ''TabletopGame/{{Aberrant}}'', Novas are immune to all [[{{Muggles}} baseline]] diseases. However, some Nova specific diseases have begun to evolve (or been created).
* ''TabletopGame/ChroniclesOfDarkness'': A number of the game's splats (including [[TabletopGame/WerewolfTheForsaken werewolves]], [[TabletopGame/PrometheanTheCreated Prometheans]], and the fan-made [[TabletopGame/LeviathanTheTempest Leviathans]]) gain their Supernatural Potency as a bonus to resist poison or disease.

* The vorcha in ''Franchise/MassEffect'' are immune to all diseases, which allowed the mostly vorcha Blood Pack mercenaries to try to take over Omega's slums when the Collector plague hit in ''VideoGame/MassEffect2''. Presumably they evolved this to counter their incredibly violent lifestyles (infection would have rendered them extinct long ago without it); even ''with'' this immunity, their lifespan is still only about thirty years on the outside.
** However, it's worth mentioning that, according to the in-game codex, they are not immune to everything "at the same time". Basically, they have clusters of unassigned stem cells (which can turn into any type of cell possible but haven't) in their bodies even during adulthood. So, when they are faced with life-threatening situations, these cells change to counter that (krogan use this in Bloodpack by beating vorcha, making them get thicker skins). If a new disease is introduced, these cells make sure that vorcha are immune, but the number of these clusters is limited and when they are used up, they can't regrow. In other words, the vorcha immune to Omega plague would have probably died if exposed to a normal deadly disease.

** In ''[[VideoGame/TheElderScrollsVSkyrim Skyrim]]'', being a werewolf likewise makes you immune to all diseases. Also, with enough skills & materials you can enchant an equipment to fully protect you from diseases, or find such items through luck (which is the prerequisite to unlock disease immunity enchantment through destroying it).

* In ''VideoGame/{{Battleborn}}'', the Jennerit's Sustainment process makes those who've undergone it not only [[TheAgeless never aging]] immortals but also grants them immunity from natural illnesses.
* ''VideoGame/CastlevaniaLordsOfShadow2'': Being a vampire cursed with CompleteImmortality, Gabriel Belmont/Dracula is naturally immune to all poisons and diseases, such as when he is exposed to an [[SyntheticPlague artificially-engineered virus]] that turns humans into monsters instantly, he is completely unaffected. There are not even ill effects for drinking their corrupted blood.

* [[Franchise/SonicTheHedgehog Shadow the Hedgehog's]] status as the UltimateLifeform isn't solely due to sheer power, it's because he's TheAgeless and has a perfect immune system, and thus biologically immortal. [[spoiler:His creator was aiming for this to save his terminally ill daughter.]]
* [[spoiler:Rosalia Rosellini]] in ''[[VideoGame/TraumaCenter Trauma Team]]'' is miraculously able to exist in perfect symbiosis with a super-virus [[spoiler:and implied MysticalPlague]] that renders her immune to any other form of disease. Unfortunately this applies only to that character, and anyone else who contracts the virus falls victim to a deadly infection with amped-up symptoms of viral hemorrhagic fever (VHF) that kills in a matter of days.

* On ''WesternAnimation/TheSimpsons'', Mr. Burns has every known disease and a few new ones.

* Archie in ''WesternAnimation/ClassOfTheTitans'' is descended from Achilles. While he lacks his ancestor's invulnerability, he does exhibit this trope, extending to immunity to supernatural plagues like the ones in Pandora's Box.

* In ''WesternAnimation/XMenTheAnimatedSeries'', Wolverine's HealingFactor also grants him quick recovery from almost any disease. This becomes a major plot point in a two-part episode: Bishop and Cable both travel back in time to prevent a bioengineered plague from wiping out mutantkind; the former is trying to prevent the disease entirely to save billions of lives in the near future, the latter is from ''further'' in the future where the virus' effect stabilized aspects of the mutant gene preventing worldwide extinction of both humans and mutants. Cable solves the problem by allowing Wolverine to get infected with the plague. Wolverine recovers in minutes, and his immune system now has antibodies that can be used to manufacture a vaccine for the plague, preventing the deadly epidemic while passing along the beneficial aspects required to preserve Cable's timeline.

* This is the plot of ''Series/TheImmortal''. The protagonist is immune to all known diseases, and a lot of people want to chase him down and get his blood because of it.