History Main / AcquiredPoisonImmunity

14th Oct '17 2:29:36 AM jormis29
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*** Played for laughs in a crossover with ''ComicBook/CaptainAmerica'', where the Joker and the ComicBook/RedSkull discover that their signature poisons are so alike that each is immune to the effects of the other.

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*** Played for laughs in a crossover with ''ComicBook/CaptainAmerica'', ''ComicBook/BatmanAndCaptainAmerica'', where the Joker and the ComicBook/RedSkull discover that their signature poisons are so alike that each is immune to the effects of the other.
1st Oct '17 1:10:49 PM Piterpicher
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For some (chiefly organic) poisons, the body produces antibodies to clear them from the system; so, with repeated exposure to small amounts, you can build up a level of circulating antibody that grants immunity to a typical dose. In the past ages, [[ScienceMarchesOn the few metallic poisons]] known were rare and expensive; therefore most poisons were plant-based alkaloids. However, there are plenty of other poisons (including nearly all heavy metals to which modern civilians and industrial workers are exposed, such as compounds of lead, radium, mercury and cadmium) that ''don't'' [[TelevisionIsTryingToKillUs get cleared from the system and simply build up in your tissues until you reach a lethal dose]].

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For some (chiefly organic) poisons, the body produces antibodies to clear them from the system; so, with repeated exposure to small amounts, you can build up a level of circulating antibody that grants immunity to a typical dose. In the past ages, [[ScienceMarchesOn the few metallic poisons]] known were rare and expensive; therefore most poisons were plant-based alkaloids. However, there are plenty of other poisons (including nearly all heavy metals to which modern civilians and industrial workers are exposed, such as compounds of lead, radium, mercury and cadmium) that ''don't'' [[TelevisionIsTryingToKillUs [[JustForFun/TelevisionIsTryingToKillUs get cleared from the system and simply build up in your tissues until you reach a lethal dose]].
25th Sep '17 1:08:35 PM SeptimusHeap
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* On ''Series/MyNameIsEarl'', Catalina has been given some tea spiked with sleeping pills by a vengeful "Crazy Witch Lady" (played by BettyWhite). She winds up in the woman's basement with Earl and company...but she ends up tying herself up, saying that because [[FridgeHorror her drinks have been spiked with so many date-rape drugs over the years]], she's developed a tolerance, but couldn't make a woman who reminded her of her aunt back home feel bad.

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* On ''Series/MyNameIsEarl'', Catalina has been given some tea spiked with sleeping pills by a vengeful "Crazy Witch Lady" (played by BettyWhite).Creator/BettyWhite). She winds up in the woman's basement with Earl and company...but she ends up tying herself up, saying that because [[FridgeHorror her drinks have been spiked with so many date-rape drugs over the years]], she's developed a tolerance, but couldn't make a woman who reminded her of her aunt back home feel bad.
19th Sep '17 12:27:09 AM Doug86
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* In Paizo's ''TabletopGame//{{Pathfinder}}'', the [[http://paizo.com/pathfinderRPG/prd/advanced/baseClasses/alchemist.html Alchemist class]] slowly gains resistance to poison over the first 9 levels of their career before finally becoming completely immune at level ten, presumably using this method.

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* In Paizo's ''TabletopGame//{{Pathfinder}}'', ''TabletopGame/{{Pathfinder}}'', the [[http://paizo.com/pathfinderRPG/prd/advanced/baseClasses/alchemist.html Alchemist class]] slowly gains resistance to poison over the first 9 levels of their career before finally becoming completely immune at level ten, presumably using this method.
8th Sep '17 11:19:36 PM ultimomant
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* In ''Fanfic/FateIngensCor'', Assassin picks up one of Archer's missed poisoned arrows and stabs herself. The poison weakens her a bit, but she quickly recovers and gloats that the poison will never affect her again.
22nd Aug '17 11:49:16 PM PaulA
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* ''[[Literature/ElementalMasters Phoenix and Ashes]]'': The aftermath of his World War I experiences has Reggie taking ''lots'' of sedatives in order to sleep at night (enough that he's getting concerned). Alison isn't aware of this, so when she injects him with opiates to keep him prisoner the dosage isn't nearly enough to do the job.

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* ''[[Literature/ElementalMasters Phoenix and Ashes]]'': ''Literature/PhoenixAndAshes'': The aftermath of his World War I experiences has Reggie taking ''lots'' of sedatives in order to sleep at night (enough that he's getting concerned). Alison isn't aware of this, so when she injects him with opiates to keep him prisoner the dosage isn't nearly enough to do the job.
5th Aug '17 10:03:20 AM Bissek
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* One ''Literature/SixteenThirtyTwo'' short story centered around a poisoning that was originally suspected to be murder until it was discovered to be an accidental suicide. The dead man had been dosing himself with arsenic regularly in an attempt to build up an immunity. Unfortunately, his regular supplier had been selling him adulterated drugs, so his immunity wasn't built up anywhere near as much as he thought. After buying a new supply from a different chemist, who sold him pure arsenic, he took what he thought was the appropriate dosage for his regimen, which was based on the weaker drugs of his first supplier. The massive dose of pure arsenic overpowered his limited immunity and killed him.
3rd Aug '17 11:21:43 AM Malady
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* The titular badger in ''TheUrthbloodSaga'', among his other powers, has built up an immunity to all but the strongest poisons from this method. One poor ferret who tried to poison him and take over his army learned this the [[CruelAndUnusualDeath hard way...]]

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* The titular badger in ''TheUrthbloodSaga'', ''Fanfic/TheUrthbloodSaga'', among his other powers, has built up an immunity to all but the strongest poisons from this method. One poor ferret who tried to poison him and take over his army learned this the [[CruelAndUnusualDeath hard way...]]
9th Jul '17 7:19:57 PM zarpaulus
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* [[http://www.webmd.com/allergies/allergy-shots Allergy immunotherapy]] is a process that gradually reduces immune responses through exposure to minute doses of the allergen. After a few months the patient only needs a booster shot a couple times a year to maintain it.
6th Jul '17 2:10:33 PM xcountryguy
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** [[spoiler: Sanji's estranged sister]] Vinsmoke [[RedBaron "Poison Pink"]] Reiju has this as well. At some point Luffy is ''very'' sick after being given a very powerful poison, but she went up to him and gave him a KissOfLife to absorb it and heal him. She has no physical side-effects afterwards.

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** [[spoiler: Sanji's [[spoiler:Sanji's estranged sister]] Vinsmoke [[RedBaron "Poison Pink"]] Reiju has this as well. At some point Luffy is ''very'' sick after being given a very powerful poison, but she went up to him and gave him a KissOfLife to absorb it and heal him. She has no physical side-effects afterwards.



* In ''Film/ThankYouForSmoking'', terrorists [[spoiler: try to kill the main character by covering him in nicotine patches, which would overwhelm any normal person, and leaving him naked on the lap of the Lincoln Memorial]]. He survives, and recovers fairly quickly, because he'd been chain smoking for years and had built up a [[BlessedWithSuck superhuman tolerance to nicotine.]] Unfortunately (fortunately?) it also means [[CursedWithAwesome he can never smoke again.]]

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* In ''Film/ThankYouForSmoking'', terrorists [[spoiler: try [[spoiler:try to kill the main character by covering him in nicotine patches, which would overwhelm any normal person, and leaving him naked on the lap of the Lincoln Memorial]]. He survives, and recovers fairly quickly, because he'd been chain smoking for years and had built up a [[BlessedWithSuck superhuman tolerance to nicotine.]] Unfortunately (fortunately?) it also means [[CursedWithAwesome he can never smoke again.]]



* ''Series/TheCape'', a 2010-2011 series, used it when the titular character, learning he was dealing with a poisoner, took it upon himself to work up an immunity to everything the guy was likely to utilize. [[spoiler: We didn't get to see if the immunities actually HELD, [[SubvertedTrope because the guy just tried to run him through.]] ]]

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* ''Series/TheCape'', a 2010-2011 series, used it when the titular character, learning he was dealing with a poisoner, took it upon himself to work up an immunity to everything the guy was likely to utilize. [[spoiler: We [[spoiler:We didn't get to see if the immunities actually HELD, [[SubvertedTrope because the guy just tried to run him through.]] ]]



* In a sketch in ''Series/HumanGiant'' a contestant practices for a literal gas guzzling contest (as in ''drinking'' gallons of petrol and yes it shown to be as deadly as that sounds) by drinking various poisons including paint thinner to build up an an immunity. [[spoiler: he wins but doesn't have a car.]]

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* In a sketch in ''Series/HumanGiant'' a contestant practices for a literal gas guzzling contest (as in ''drinking'' gallons of petrol and yes it shown to be as deadly as that sounds) by drinking various poisons including paint thinner to build up an an immunity. [[spoiler: he [[spoiler:he wins but doesn't have a car.]]



* In the Halloween episode of ''Series/GameShakers'', "Scared Tripless, this was part of the prank Double G played on the kids, primarily his son. [[spoiler: Since the previous Halloween, he had been taking small amounts of venom so he can fake his death after being bitten by a snake.]] While it is successful, he forgets that [[spoiler: snake bites can become infected and the doctors have to give him a shot in his butt to prevent it.]]

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* In the Halloween episode of ''Series/GameShakers'', "Scared Tripless, this was part of the prank Double G played on the kids, primarily his son. [[spoiler: Since [[spoiler:Since the previous Halloween, he had been taking small amounts of venom so he can fake his death after being bitten by a snake.]] While it is successful, he forgets that [[spoiler: snake [[spoiler:snake bites can become infected and the doctors have to give him a shot in his butt to prevent it.]]



* In ''Franchise/FinalFantasyCrystalChronicles'', you meet the Selkie De Nam, who decides that the best way to deal with the deadly Miasma is to try to build up a resistance to it by drinking water with miasma mixed in. [[spoiler: It doesn't end well]].

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* In ''Franchise/FinalFantasyCrystalChronicles'', you meet the Selkie De Nam, who decides that the best way to deal with the deadly Miasma is to try to build up a resistance to it by drinking water with miasma mixed in. [[spoiler: It [[spoiler:It doesn't end well]].



* In ''VideoGame/MassEffect2'', failure to realise that without constant supervision, a sedated Shepard won't stay that way for long, ends up foiling [[spoiler: the [[BrainwashedAndCrazy Indoctrinated]] Alliance agents]] in ''The Arrival''. One medical report in ''The Arrival'' even mentions their frustration that it was necessary to ''increase'' every round of sedatives administered because Shepard's system simply grew immune to the previous dose, given only ''four'' hours earlier.

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* In ''VideoGame/MassEffect2'', failure to realise that without constant supervision, a sedated Shepard won't stay that way for long, ends up foiling [[spoiler: the [[spoiler:the [[BrainwashedAndCrazy Indoctrinated]] Alliance agents]] in ''The Arrival''. One medical report in ''The Arrival'' even mentions their frustration that it was necessary to ''increase'' every round of sedatives administered because Shepard's system simply grew immune to the previous dose, given only ''four'' hours earlier.



* In ''VideoGame/BatmanArkhamKnight'', Scarecrow has acquired partial immunity to his own fear toxin. However, [[spoiler: a large enough dose can overpower it, and like in the ''Blackest Night'' example, he still does fear Batman.]]

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* In ''VideoGame/BatmanArkhamKnight'', Scarecrow has acquired partial immunity to his own fear toxin. However, [[spoiler: a [[spoiler:a large enough dose can overpower it, and like in the ''Blackest Night'' example, he still does fear Batman.]]
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